Searching for up to 100 curated homologs for 349909 FitnessBrowser__Btheta:349909 (349 a.a.)
Found high-coverage hits (≥70%) to 45 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
wbjB / Q9KID0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Pseudomonas aeruginosa (see 2 papers)
64% identity, 96% coverage of query (436 bits)
V5RBP5 UDP-glucose 4-epimerase (EC 5.1.3.2) from Acinetobacter baumannii (see paper)
62% identity, 98% coverage of query (430 bits)
CAPD_RICPR / Q9ZDJ5 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Rickettsia prowazekii (strain Madrid E) (see paper)
61% identity, 97% coverage of query (429 bits)
wbvB / Q8L348 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Vibrio cholerae O37 (see 3 papers)
61% identity, 98% coverage of query (429 bits)
A0A0H3JPH0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Staphylococcus aureus (see paper)
61% identity, 97% coverage of query (423 bits)
3w1vA / A0A0H3JPH0 Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with inihibitor (see paper)
61% identity, 97% coverage of query (421 bits)
4g5hA Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with by-product
61% identity, 97% coverage of query (421 bits)
3vvcA Crystal structure of capsular polysaccharide synthesizing enzyme cape , k126e, in apo form
60% identity, 97% coverage of query (400 bits)
4j2oC / P37362 Crystal structure of NADP-bound wbjb from a. Baumannii community strain d1279779 (see paper)
60% identity, 96% coverage of query (399 bits)
3vvbA / A0A0H3JPH0 Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in apo form (see paper)
53% identity, 97% coverage of query (328 bits)
BC_3750 / Q81A42 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.135) from Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) (see 5 papers)
Q81A42 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Bacillus cereus (see 2 papers)
45% identity, 77% coverage of query (231 bits)
6bwcC X-ray structure of pen from bacillus thuringiensis (see paper)
37% identity, 82% coverage of query (208 bits)
pseB / O25511 UDP-N-acetylglucosamine 4,6-dehydratase subunit (EC 4.2.1.115) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 4 papers)
PSEB_HELPY / O25511 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see 3 papers)
38% identity, 82% coverage of query (204 bits)
2gn4A / O25511 Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADPH and udp-glcnac (see paper)
38% identity, 82% coverage of query (204 bits)
Q6VYQ6 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Helicobacter pylori (see paper)
39% identity, 82% coverage of query (204 bits)
2gnaA Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-gal
38% identity, 82% coverage of query (204 bits)
2gn9A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-glc
38% identity, 82% coverage of query (204 bits)
2gn6A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-glcnac
38% identity, 82% coverage of query (204 bits)
2gn8A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp
39% identity, 80% coverage of query (204 bits)
Q6VYQ5 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Helicobacter pylori (see paper)
38% identity, 82% coverage of query (203 bits)
PSEB_CAMJJ / Q5QKR8 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176) (see 2 papers)
40% identity, 82% coverage of query (202 bits)
PSEB_CAMJE / Q0P8W4 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
39% identity, 86% coverage of query (199 bits)
G5CSR9 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Megavirus chiliensis (see paper)
35% identity, 88% coverage of query (179 bits)
4tqgA / G5CSR9 Crystal structure of megavirus udp-glcnac 4,6-dehydratase, 5-epimerase mg534 (see paper)
33% identity, 88% coverage of query (161 bits)
wbiI / GI|3135688 putative epimerase/dehydratase WbiI from Burkholderia pseudomallei (see paper)
35% identity, 79% coverage of query (156 bits)
P72145 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Pseudomonas aeruginosa (see paper)
34% identity, 78% coverage of query (155 bits)
wbpM / Q9KIC5 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Pseudomonas aeruginosa (see 6 papers)
35% identity, 77% coverage of query (155 bits)
cpsE polysaccharide capsule synthesis protein CpsE from Streptococcus iniae (see paper)
36% identity, 78% coverage of query (153 bits)
EPSC_BACSU / P71052 Probable polysaccharide biosynthesis protein EpsC from Bacillus subtilis (strain 168) (see paper)
37% identity, 78% coverage of query (147 bits)
wbgZ / Q9F736 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Shigella sonnei (see paper)
34% identity, 78% coverage of query (145 bits)
RfbU / CAA69127.1 mannosyl-transferase from Vibrio cholerae (see paper)
35% identity, 77% coverage of query (141 bits)
wbkD / Q2YMM0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Brucella abortus (strain 2308) (see 2 papers)
32% identity, 84% coverage of query (137 bits)
5bjuA / O86159 X-ray structure of the pglf dehydratase from campylobacter jejuni in complex with udp and NAD(h) (see paper)
33% identity, 87% coverage of query (134 bits)
pglF / Q0P9D4 UDP-N-acetylglucosamine C-6 dehydratase (EC 4.2.1.135) from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see 3 papers)
PGLF_CAMJE / Q0P9D4 UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase; UDP-GlcNAc C6 dehydratase; Protein glycosylation pathway protein F; UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining); EC 4.2.1.135 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
33% identity, 86% coverage of query (134 bits)
5bjvA X-ray structure of the pglf udp-n-acetylglucosamine 4,6-dehydratase from campylobacterjejuni, d396n/k397a variant in complex with udp-n- acrtylglucosamine
32% identity, 87% coverage of query (130 bits)
Build an alignment for 349909 and 35 homologs with ≥ 30% identity
Or download the sequences
3pvzB / Q5E8L1 Udp-n-acetylglucosamine 4,6-dehydratase from vibrio fischeri
26% identity, 72% coverage of query (84.0 bits)
tylA2 / Q54144 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces fradiae (see 2 papers)
25% identity, 79% coverage of query (61.6 bits)
Q9ZV36 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
25% identity, 71% coverage of query (52.4 bits)
Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
23% identity, 71% coverage of query (51.6 bits)
N0A8N8 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
24% identity, 72% coverage of query (51.2 bits)
8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
22% identity, 72% coverage of query (48.9 bits)
N0A422 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
24% identity, 71% coverage of query (48.1 bits)
Q9AV98 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Pisum sativum (see paper)
uxs1 / BAB40967.1 UDP-D-glucuronate carboxy-lyase from Pisum sativum (see paper)
24% identity, 72% coverage of query (47.8 bits)
3aw9A / A3MUJ4 Structure of udp-galactose 4-epimerase mutant
24% identity, 70% coverage of query (44.3 bits)
RHM1 / Q9SYM5 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM1 (EC 4.2.1.76) from Arabidopsis thaliana (see 3 papers)
RHM1_ARATH / Q9SYM5 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1; Protein REPRESSOR OF LRX1 1; Rhamnose biosynthetic enzyme 1; AtRHM1; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
25% identity, 75% coverage of query (43.1 bits)
Or start over
Lawrence Berkeley National Laboratory