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Searching for up to 100 curated homologs for 349939 FitnessBrowser__Btheta:349939 (268 a.a.)

Found high-coverage hits (≥70%) to 46 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Amt / b4214 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
cysQ / P22255 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) from Escherichia coli (strain K12) (see 7 papers)
CYSQ_ECOLI / P22255 3'(2'),5'-bisphosphate nucleotidase CysQ; 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase; EC 3.1.3.7 from Escherichia coli (strain K12) (see 5 papers)
    47% identity, 96% coverage of query (165 bits)

pssB / AAA81571.1 pssB from Rhizobium leguminosarum (see paper)
    41% identity, 98% coverage of query (162 bits)

Build an alignment

Build an alignment for 349939 and 2 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

Q5U789 L-galactose 1-phosphate phosphatase (EC 3.1.3.93) from Actinidia deliciosa (see paper)
    27% identity, 99% coverage of query (78.6 bits)

SUHB_SALT1 / A0A0F6B4W4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Salmonella typhimurium (strain 14028s / SGSC 2262) (see paper)
    28% identity, 87% coverage of query (77.0 bits)

hisN / Q8NS80 histidinol-phosphatase (EC 3.1.3.15) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 2 papers)
HISN_CORGL / Q8NS80 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
Q8NS80 histidinol-phosphatase (EC 3.1.3.15) from Corynebacterium glutamicum (see 2 papers)
    29% identity, 71% coverage of query (75.5 bits)

SsyA / b2533 Nus factor SuhB (EC 3.1.3.25; EC 3.1.3.19) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
suhB / P0ADG4 Nus factor SuhB (EC 3.1.3.25; EC 3.1.3.19) from Escherichia coli (strain K12) (see 16 papers)
SUHB_ECOLI / P0ADG4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Escherichia coli (strain K12) (see 14 papers)
    27% identity, 87% coverage of query (73.9 bits)

IMP1_SOLLC / P54926 Inositol monophosphatase 1; IMP 1; IMPase 1; LeIMP1; Inositol-1(or 4)-monophosphatase 1; EC 3.1.3.25 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
    26% identity, 96% coverage of query (73.6 bits)

6ib8B / P0ADG4 Structure of a complex of suhb and nusa ar2 domain (see paper)
    27% identity, 87% coverage of query (73.6 bits)

2qflA Structure of suhb: inositol monophosphatase and extragenic suppressor from e. Coli
    28% identity, 87% coverage of query (73.6 bits)

B3DFH0 inositol-phosphate phosphatase (EC 3.1.3.25) from Hordeum vulgare (see paper)
    28% identity, 91% coverage of query (70.9 bits)

IMP2_SOLLC / P54927 Inositol monophosphatase 2; IMP 2; IMPase 2; LeIMP2; Inositol-1(or 4)-monophosphatase 2; EC 3.1.3.25 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see 2 papers)
    29% identity, 92% coverage of query (69.7 bits)

B3GK03 L-galactose 1-phosphate phosphatase (EC 3.1.3.93) from Nicotiana tabacum (see paper)
    26% identity, 89% coverage of query (69.7 bits)

TM1415 / O33832 inositol monophosphatase subunit (EC 3.1.3.25) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
BSUHB_THEMA / O33832 Fructose-1,6-bisphosphatase/inositol-1-monophosphatase; FBPase/IMPase; Inositol-1-phosphatase; I-1-Pase; EC 3.1.3.11; EC 3.1.3.25 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 3 papers)
O33832 inositol-phosphate phosphatase (EC 3.1.3.25) from Thermotoga maritima (see paper)
2p3nA / O33832 Thermotoga maritima impase tm1415 (see paper)
    28% identity, 78% coverage of query (69.3 bits)

6tqoT Rrn anti-termination complex
    27% identity, 87% coverage of query (67.4 bits)

IMP3_SOLLC / P54928 Inositol monophosphatase 3; IMP 3; IMPase 3; LeIMP3; Inositol-1(or 4)-monophosphatase 3; EC 3.1.3.25 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
    27% identity, 91% coverage of query (67.0 bits)

5zonA / P95189 Histidinol phosphate phosphatase from mycobacterium tuberculosis (see paper)
    27% identity, 79% coverage of query (66.6 bits)

5yhtA Crystal structure of a phosphatase from mycobacterium tuberculosis in complex with its substrate
    27% identity, 79% coverage of query (66.6 bits)

HISN_MYCTU / P95189 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P95189 histidinol-phosphatase (EC 3.1.3.15) from Mycobacterium tuberculosis (see paper)
    28% identity, 79% coverage of query (66.2 bits)

SUHB_PSEAE / Q9HXI4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
    29% identity, 87% coverage of query (65.5 bits)

3lv0A / A0A0H3M6W8 Crystal structure of extragenic suppressor protein suhb from bartonella henselae, native
    27% identity, 87% coverage of query (65.1 bits)

SUHB_BACSU / Q45499 Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25; EC 3.1.3.5 from Bacillus subtilis (strain 168) (see paper)
    26% identity, 87% coverage of query (63.9 bits)

IMPA2_MOUSE / Q91UZ5 Inositol monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2; EC 3.1.3.25 from Mus musculus (Mouse) (see paper)
Q91UZ5 inositol-phosphate phosphatase (EC 3.1.3.25) from Mus musculus (see paper)
    28% identity, 87% coverage of query (63.5 bits)

A0A1I9GET0 inositol-phosphate phosphatase (EC 3.1.3.25) from Staphylococcus aureus (see 2 papers)
    27% identity, 83% coverage of query (62.8 bits)

2hhmA Structure of inositol monophosphatase, the putative target of lithium therapy
    29% identity, 87% coverage of query (62.8 bits)

1imbA Structural analysis of inositol monophosphatase complexes with substrates
    29% identity, 87% coverage of query (62.8 bits)

1awbA Human myo-inositol monophosphatase in complex with d-inositol-1- phosphate and calcium
    29% identity, 87% coverage of query (62.8 bits)

6giuA / P29218 Human impase with l-690330 (see paper)
    29% identity, 87% coverage of query (62.4 bits)

IMPA1 / P29218 inositol monophosphatase 1 monomer (EC 3.1.3.25) from Homo sapiens (see 5 papers)
IMPA1_HUMAN / P29218 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Homo sapiens (Human) (see 9 papers)
P29218 inositol-phosphate phosphatase (EC 3.1.3.25) from Homo sapiens (see 4 papers)
    29% identity, 87% coverage of query (62.4 bits)

1imdA Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis
    29% identity, 87% coverage of query (62.4 bits)

6zk0AAA human impase with ebselen
    29% identity, 87% coverage of query (62.4 bits)

4as4A Structure of human inositol monophosphatase 1
    29% identity, 87% coverage of query (62.4 bits)

IMPA2 / O14732 inositol monophosphatase 2 monomer (EC 3.1.3.25) from Homo sapiens (see 5 papers)
IMPA2_HUMAN / O14732 Inositol monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2; EC 3.1.3.25 from Homo sapiens (Human) (see 3 papers)
    29% identity, 88% coverage of query (61.6 bits)

4as5A / O55023 Structure of mouse inositol monophosphatase 1 (see paper)
    27% identity, 87% coverage of query (60.8 bits)

5dw8A Crystal structure of 2'amp bound saimpase-ii
    27% identity, 75% coverage of query (60.5 bits)

IMPA1_RAT / P97697 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Rattus norvegicus (Rat) (see 2 papers)
P97697 inositol-phosphate phosphatase (EC 3.1.3.25) from Rattus norvegicus (see 2 papers)
    28% identity, 87% coverage of query (60.5 bits)

2cziA / O14732 Crystal structure of human myo-inositol monophosphatase 2 (impa2) with calcium and phosphate ions (see paper)
    29% identity, 88% coverage of query (60.5 bits)

IMPA1_MOUSE / O55023 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Mus musculus (Mouse) (see 3 papers)
O55023 inositol-phosphate phosphatase (EC 3.1.3.25) from Mus musculus (see 2 papers)
    27% identity, 87% coverage of query (59.7 bits)

5j16A Crystal structure of inositol monophosphate bound saimpase-ii
    27% identity, 73% coverage of query (58.5 bits)

IMPA1_CAEEL / Q19420 Inositol monophosphatase ttx-7; IMP; IMPase; Abnormal thermotaxis protein 7; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase; EC 3.1.3.25; EC 3.1.3.94 from Caenorhabditis elegans (see 2 papers)
    24% identity, 87% coverage of query (55.8 bits)

IMPA1_BOVIN / P20456 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Bos taurus (Bovine) (see 2 papers)
    27% identity, 87% coverage of query (55.8 bits)

2bjiA / P20456 High resolution structure of myo-inositol monophosphatase, the target of lithium therapy (see paper)
    27% identity, 87% coverage of query (55.5 bits)

DPNP1_ARATH / Q42546 SAL1 phosphatase; 3'(2'),5'-bisphosphate nucleotidase 1; 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase 1; DPNPase 1; Inositol polyphosphate 1-phosphatase 1; IPPase 1; Inositol-1,4-bisphosphate 1-phosphatase 1; Protein FIERY 1; EC 3.1.3.7; EC 3.1.3.57 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q42546 inositol-1,4-bisphosphate 1-phosphatase (EC 3.1.3.57); 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) from Arabidopsis thaliana (see paper)
    23% identity, 87% coverage of query (51.2 bits)

8f9yA / Q42546 Sal1 from arabidopsis thaliana (see paper)
    23% identity, 87% coverage of query (51.2 bits)

Q3LS17 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) from Arthrospira platensis (see paper)
    24% identity, 88% coverage of query (48.1 bits)

IMPA_MYCTU / O53907 Probable inositol 1-monophosphatase ImpA; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    23% identity, 88% coverage of query (47.0 bits)

1jp4A Crystal structure of an enzyme displaying both inositol-polyphosphate 1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities
    27% identity, 94% coverage of query (44.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory