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Searching for up to 100 curated homologs for 349957 FitnessBrowser__Btheta:349957 (194 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

iorB / A0A5C0XRQ6 indolepyruvate ferredoxin oxidoreductase β subunit (EC 1.2.7.8) from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see paper)
    35% identity, 98% coverage of query (113 bits)

O07836 indolepyruvate ferredoxin oxidoreductase (subunit 1/2) (EC 1.2.7.8) from Thermococcus kodakarensis (see paper)
    33% identity, 98% coverage of query (108 bits)

IORB_METTM / P80911 Indolepyruvate oxidoreductase subunit IorB; IOR; Indolepyruvate ferredoxin oxidoreductase subunit beta; EC 1.2.7.8 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    34% identity, 96% coverage of query (107 bits)

Q6LZB5 indolepyruvate ferredoxin oxidoreductase (subunit 1/2) (EC 1.2.7.8) from Methanococcus maripaludis (see paper)
    31% identity, 95% coverage of query (87.0 bits)

Q6M0F6 indolepyruvate ferredoxin oxidoreductase (subunit 1/2) (EC 1.2.7.8) from Methanococcus maripaludis (see paper)
    34% identity, 99% coverage of query (82.8 bits)

Build an alignment

Build an alignment for 349957 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

VORA_METTM / P80907 Ketoisovalerate oxidoreductase subunit VorA; VOR; 2-oxoisovalerate oxidoreductase alpha chain; 2-oxoisovalerate-ferredoxin oxidoreductase subunit alpha; EC 1.-.-.- from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    28% identity, 98% coverage of query (65.9 bits)

korG / Q6LXN4 2-oxoglutarate ferredoxin oxidoreductase γ subunit (EC 1.2.7.3) from Methanococcus maripaludis (strain S2 / LL) (see 2 papers)
    34% identity, 79% coverage of query (60.1 bits)

KORC_METTM / P80906 2-oxoglutarate synthase subunit KorC; 2-ketoglutarate oxidoreductase gamma chain; KOR; 2-oxoglutarate-ferredoxin oxidoreductase subunit gamma; EC 1.2.7.3 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    29% identity, 97% coverage of query (60.1 bits)

D3DIA3 2-oxoglutarate synthase (subunit 3/5) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see 2 papers)
    27% identity, 86% coverage of query (53.5 bits)

salQ / B0L7F0 5-chloro-4-hydroxy-2-oxopentanoate decarboxylase (acylating) from Salinispora tropica (see paper)
    25% identity, 95% coverage of query (53.5 bits)

korA / Q9AJM0 2-oxoglutarate:ferredoxin oxidoreductase α subunit (EC 1.2.7.3) from Hydrogenobacter thermophilus (see paper)
Q9AJM0 2-oxoglutarate synthase (subunit 2/2) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see 3 papers)
    28% identity, 88% coverage of query (52.4 bits)

P80523 pyruvate synthase (subunit 2/4) (EC 1.2.7.1) from Methanosarcina barkeri (see paper)
    27% identity, 85% coverage of query (52.0 bits)

6n2oC 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound
    26% identity, 99% coverage of query (51.6 bits)

6n2oA 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound
    26% identity, 99% coverage of query (51.6 bits)

6n2nA / A0L8G4 Crystal structure of 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus (see paper)
    26% identity, 99% coverage of query (51.6 bits)

Q51799 pyruvate synthase (subunit 1/4) (EC 1.2.7.1) from Pyrococcus furiosus (see 2 papers)
    23% identity, 85% coverage of query (48.5 bits)

O87870 2-oxoglutarate synthase (subunit 2/2) (EC 1.2.7.3) from Thauera aromatica (see paper)
    23% identity, 97% coverage of query (48.1 bits)

Pfo / b1378 putative pyruvate-flavodoxin oxidoreductase (EC 1.2.7.1) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ydbK / P52647 putative pyruvate-flavodoxin oxidoreductase (EC 1.2.7.1) from Escherichia coli (strain K12) (see 6 papers)
    27% identity, 98% coverage of query (46.2 bits)

W8CQB1 pyruvate synthase (subunit 2/4) (EC 1.2.7.1); pyruvate decarboxylase (subunit 2/4) (EC 4.1.1.1) from Thermococcus guaymasensis (see paper)
    25% identity, 85% coverage of query (45.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory