Sites on a Tree

 

Searching for up to 100 curated homologs for 350016 BT0488 2-dehydro-3-deoxygluconokinase (NCBI ptt file) (341 a.a.)

Found high-coverage hits (≥70%) to 40 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

kdgK / Q9WXS2 2-keto-3-deoxygluconate kinase (EC 2.7.1.178) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9WXS2 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Thermotoga maritima (see paper)
    55% identity, 99% coverage of query (370 bits)

2afbA / Q9WXS2 Crystal structure of 2-dehydro-3- deoxygluconokinase (ec 2.7.1.45) (tm0067) from thermotoga maritima at 2.05 a resolution (see paper)
    54% identity, 97% coverage of query (353 bits)

A0A0B6VMB0 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Flavobacterium sp. UMI-01 (see paper)
    47% identity, 99% coverage of query (314 bits)

KDGK1_HALVD / D4GSE6 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxygluconate/2-keto-3-deoxygalactonate kinase; KDG kinase; KDGK-1; EC 2.7.1.178 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GSE6 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Haloferax volcanii (see paper)
    34% identity, 98% coverage of query (182 bits)

Build an alignment

Build an alignment for 350016 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

3ktnA / Q837J7 Crystal structure of a putative 2-keto-3-deoxygluconate kinase from enterococcus faecalis
    28% identity, 95% coverage of query (166 bits)

CA265_RS19865 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45) from Pedobacter sp. GW460-11-11-14-LB5
    30% identity, 96% coverage of query (162 bits)

KDGK2_HALVD / D4GR05 2-dehydro-3-deoxygalactonokinase; 2-keto-3-deoxygalactonate kinase; KDGal kinase; KDGK-2; EC 2.7.1.58 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GR05 6-phosphofructokinase (EC 2.7.1.11); 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178); 2-dehydro-3-deoxygalactonokinase (EC 2.7.1.58) from Haloferax volcanii (see 2 papers)
    34% identity, 98% coverage of query (152 bits)

2dcnA / Q96XN9 Crystal structure of 2-keto-3-deoxygluconate kinase from sulfolobus tokodaii complexed with 2-keto-6-phosphogluconate (alpha-furanose form)
    29% identity, 96% coverage of query (93.6 bits)

KDGK_SULTO / Q96XN9 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxy-D-gluconate kinase; KDG kinase; KDGK; EC 2.7.1.45 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
Q96XN9 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Sulfurisphaera tokodaii (see paper)
    29% identity, 96% coverage of query (93.6 bits)

KDGK_THETE / Q704D0 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermoproteus tenax (see paper)
kdgK / CAF18464.1 2-Keto-3-deoxy-gluconate kinase from Thermoproteus tenax (see paper)
    29% identity, 96% coverage of query (87.0 bits)

kdgK / Q97U29 2-dehydro-3-deoxyglucono/2-dehydro-3-deoxygalactonokinase monomer (EC 2.7.1.178) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see 3 papers)
KDGK_SACS2 / Q97U29 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxy-galactonokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; KDGal kinase; EC 2.7.1.178 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
Q97U29 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178) from Saccharolobus solfataricus (see 5 papers)
    27% identity, 94% coverage of query (84.7 bits)

2varA / Q97U29 Crystal structure of sulfolobus solfataricus 2-keto-3-deoxygluconate kinase complexed with 2-keto-3-deoxygluconate (see paper)
    27% identity, 94% coverage of query (84.7 bits)

PFKB_THETC / D9TT10 ATP-dependent 6-phosphofructokinase; ATP-PFK; Phosphofructokinase; EC 2.7.1.11 from Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032) (Clostridium thermosaccharolyticum) (see paper)
    22% identity, 90% coverage of query (75.1 bits)

KDGK_BACSU / P50845 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Bacillus subtilis (strain 168) (see paper)
    24% identity, 96% coverage of query (67.8 bits)

N515DRAFT_1919 Fructokinase (EC 2.7.1.4) from Dyella japonica UNC79MFTsu3.2
    27% identity, 98% coverage of query (65.5 bits)

Q0K080 dehydrogluconokinase (EC 2.7.1.13); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus necator (see paper)
    23% identity, 85% coverage of query (64.7 bits)

kdgK / P45416 2-dehydro-3-deoxy-D-gluconate kinase (EC 2.7.1.178) from Dickeya dadantii (strain 3937) (see 2 papers)
KDGK_DICD3 / P45416 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    24% identity, 89% coverage of query (61.6 bits)

Sama_0561 Fructokinase (EC 2.7.1.4) from Shewanella amazonensis SB2B
    25% identity, 97% coverage of query (61.6 bits)

Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    25% identity, 94% coverage of query (61.2 bits)

KDGK_ECOLW / E0J5J4 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / LMG 11080 / NBRC 13500 / NCIMB 8666 / NRRL B-766 / W) (see paper)
    25% identity, 86% coverage of query (60.8 bits)

YhjI / b3526 2-dehydro-3-deoxygluconokinase (EC 2.7.1.178; EC 2.7.1.45) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
kdgK / P37647 2-dehydro-3-deoxygluconokinase (EC 2.7.1.178) from Escherichia coli (strain K12) (see 4 papers)
KDGK_ECOLI / P37647 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Escherichia coli (strain K12) (see paper)
    24% identity, 86% coverage of query (60.8 bits)

Q9M1B9 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    25% identity, 97% coverage of query (60.8 bits)

SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
    25% identity, 96% coverage of query (60.8 bits)

Echvi_2804 Fructokinase (EC 2.7.1.4) from Echinicola vietnamensis KMM 6221, DSM 17526
    22% identity, 98% coverage of query (60.5 bits)

PGA1_c07240 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92) from Phaeobacter inhibens BS107
    25% identity, 91% coverage of query (60.5 bits)

iolC / P42414 5-dehydro-2-deoxy-D-gluconate kinase (EC 2.7.1.92) from Bacillus subtilis (strain 168) (see 2 papers)
IOLC_BACSU / P42414 5-dehydro-2-deoxygluconokinase; 2-deoxy-5-keto-D-gluconate kinase; DKG kinase; EC 2.7.1.92 from Bacillus subtilis (strain 168) (see paper)
    22% identity, 96% coverage of query (59.7 bits)

SCRK1_ORYSJ / Q0JGZ6 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
    25% identity, 96% coverage of query (59.3 bits)

Q9SID0 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    24% identity, 85% coverage of query (59.3 bits)

Q42896 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    24% identity, 84% coverage of query (58.9 bits)

O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    24% identity, 84% coverage of query (58.9 bits)

Q42645 fructokinase (EC 2.7.1.4) from Beta vulgaris (see paper)
    24% identity, 85% coverage of query (58.2 bits)

Q9LNE4 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    24% identity, 96% coverage of query (57.4 bits)

scrK / Q9ZHJ6 fructokinase (EC 2.7.1.4) from Clostridium beijerinckii (see paper)
    22% identity, 85% coverage of query (56.6 bits)

SCRK1_MAIZE / Q6XZ79 Fructokinase-1; ZmFRK1; EC 2.7.1.4 from Zea mays (Maize)
    24% identity, 92% coverage of query (56.6 bits)

RBSK_STAAC / A0A0H2WZY4 Ribokinase; RK; EC 2.7.1.15 from Staphylococcus aureus (strain COL) (see paper)
A0A0H2WZY4 ribokinase (EC 2.7.1.15) from Staphylococcus aureus (see paper)
    24% identity, 91% coverage of query (54.3 bits)

SCRK2_ORYSI / A2YQL4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
SCRK2_ORYSJ / Q0J8G4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
A2YQL4 fructokinase (EC 2.7.1.4) from Oryza sativa (see paper)
    25% identity, 84% coverage of query (52.8 bits)

Q9FLH8 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    23% identity, 84% coverage of query (49.7 bits)

8cqxA / A0A0B0SD75 Ribokinase from t.Sp mutant a92g
    24% identity, 93% coverage of query (49.3 bits)

3ih0A / O59128 Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with amp-pnp
    20% identity, 84% coverage of query (44.7 bits)

3gbuA Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with atp
    20% identity, 84% coverage of query (44.7 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory