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Searching for up to 100 curated homologs for 350353 FitnessBrowser__Btheta:350353 (479 a.a.)

Found high-coverage hits (≥70%) to 21 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

UxaB / b1521 tagaturonate reductase (EC 1.1.1.58) from Escherichia coli K-12 substr. MG1655 (see 11 papers)
uxaB / P0A6L7 tagaturonate reductase (EC 1.1.1.58) from Escherichia coli (strain K12) (see 10 papers)
    45% identity, 99% coverage of query (412 bits)

A9QSF6 tagaturonate reductase (EC 1.1.1.58) from Lactococcus lactis (see paper)
    44% identity, 100% coverage of query (389 bits)

CA265_RS19880 Altronate oxidoreductase (EC 1.1.1.58) from Pedobacter sp. GW460-11-11-14-LB5
    37% identity, 99% coverage of query (288 bits)

Build an alignment

Build an alignment for 350353 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

YeiQ / b2172 putative oxidoreductase YeiQ from Escherichia coli K-12 substr. MG1655 (see 2 papers)
    26% identity, 98% coverage of query (130 bits)

UxuB / b4323 D-mannonate oxidoreductase (EC 1.1.1.57) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
uxuB / P39160 D-mannonate oxidoreductase (EC 1.1.1.57) from Escherichia coli (strain K12) (see 4 papers)
    25% identity, 97% coverage of query (117 bits)

4im7A / A0A0H2V7F2 Crystal structure of fructuronate reductase (ydfi) from e. Coli cft073 (efi target efi-506389) complexed with nadh and d-mannonate
    25% identity, 90% coverage of query (112 bits)

YdfI / b1542 putative oxidoreductase YdfI from Escherichia coli K-12 substr. MG1655 (see 2 papers)
    25% identity, 90% coverage of query (112 bits)

R9UHL6 mannitol 2-dehydrogenase (EC 1.1.1.67) from Saccharina japonica (see paper)
    26% identity, 90% coverage of query (105 bits)

7rk5B / Q4WQY4 Mannitol-2-dehydrogenase bound to nadh from aspergillus fumigatus
    25% identity, 97% coverage of query (105 bits)

M2DH_ASPFU / Q4WQY4 Mannitol 2-dehydrogenase; M2DH; MDH; EC 1.1.1.67 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
Q4WQY4 mannitol 2-dehydrogenase (EC 1.1.1.67) from Aspergillus fumigatus (see 2 papers)
    25% identity, 97% coverage of query (104 bits)

DSF1_YEAST / P0CX08 Mannitol dehydrogenase DSF1; Deletion suppressor of MPT5 mutation protein 1; EC 1.1.1.67 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
MAN2_YEAST / P0CX09 Mannitol dehydrogenase 2; EC 1.1.1.67 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    24% identity, 99% coverage of query (94.0 bits)

1lj8A / O08355 Crystal structure of mannitol dehydrogenase in complex with NAD (see paper)
    23% identity, 99% coverage of query (80.5 bits)

1m2wA Pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with NAD and d-mannitol
    23% identity, 99% coverage of query (80.5 bits)

O08355 mannitol 2-dehydrogenase (EC 1.1.1.67) from Pseudomonas fluorescens (see 5 papers)
    23% identity, 99% coverage of query (80.1 bits)

I3E3X0 mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) from Bacillus methanolicus (see 2 papers)
    24% identity, 79% coverage of query (79.0 bits)

sr / BAB83933.1 L-sorbose reductase from Gluconobacter oxydans (see paper)
    23% identity, 80% coverage of query (74.7 bits)

Q9KWR5 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Gluconobacter oxydans (see paper)
    23% identity, 80% coverage of query (72.0 bits)

A8YYC5 mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) from Staphylococcus aureus (see paper)
    23% identity, 80% coverage of query (63.5 bits)

MTLD_ASPFU / Q4X1A4 Mannitol-1-phosphate 5-dehydrogenase; M1PDH; MPD; MPDH; EC 1.1.1.17 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 2 papers)
Q4X1A4 mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) from Aspergillus fumigatus (see paper)
    23% identity, 88% coverage of query (58.9 bits)

MtlD / b3600 mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
mtlD / P09424 mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) from Escherichia coli (strain K12) (see 9 papers)
MTLD_ECOLI / P09424 Mannitol-1-phosphate 5-dehydrogenase; EC 1.1.1.17 from Escherichia coli (strain K12) (see paper)
P09424 mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) from Escherichia coli (see paper)
    22% identity, 80% coverage of query (58.5 bits)

MTLD_ASPNG / Q8NJJ1 Mannitol-1-phosphate 5-dehydrogenase; M1PDH; MPD; MPDH; EC 1.1.1.17 from Aspergillus niger (see 2 papers)
    21% identity, 88% coverage of query (55.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory