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Searching for up to 100 curated homologs for 351279 FitnessBrowser__Btheta:351279 (408 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

GBUA_LISM4 / Q9RR46 Glycine betaine/carnitine transport ATP-binding protein GbuA; EC 7.6.2.9 from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
    53% identity, 99% coverage of query (425 bits)

TC 3.A.1.12.9 / Q8U4S5 OtaA, component of The salt-induced glycine betaine OtaABC transporter from Methanosarcina mazei (see 2 papers)
    55% identity, 93% coverage of query (419 bits)

TC 3.A.1.12.5 / Q9RQ06 BusAA, component of Uptake system for glycine-betaine (high affinity) and proline (low affinity) (OpuAA-OpuABC) or BusAA-ABC of Lactococcus lactis). BusAA, the ATPase subunit, has a C-terminal tandem cystathionine β-synthase (CBS) domain which is the cytoplasmic K+ sensor for osmotic stress (osmotic strength)while the BusABC subunit has the membrane and receptor domains fused to each other (Biemans-Oldehinkel et al., 2006; Mahmood et al., 2006; Gul et al. 2012). An N-terminal amphipathic α-helix of OpuA is necessary for high activity but is not critical for biogenesis or the ionic regulation of transport from Lactococcus lactis (see paper)
    52% identity, 93% coverage of query (399 bits)

OPUAA_BACSU / P46920 Glycine betaine transport ATP-binding protein OpuAA; Quaternary-amine-transporting ATPase; EC 7.6.2.9 from Bacillus subtilis (strain 168) (see 2 papers)
P46920 ABC-type quaternary amine transporter (EC 7.6.2.9) from Bacillus subtilis (see paper)
TC 3.A.1.12.2 / P46920 OPAA aka OpuAA, component of Glycine betaine OpuAA/AB/AC porter (also transports dimethylsulfonioacetate and dimethylsulfoniopropionate) from Bacillus subtilis (see 4 papers)
    52% identity, 97% coverage of query (398 bits)

7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
    50% identity, 94% coverage of query (380 bits)

7ahhC Opua inhibited inward-facing, sbd docked
    50% identity, 94% coverage of query (380 bits)

ProU / b2677 glycine betaine ABC transporter ATP binding subunit ProV (EC 7.6.2.9) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
proV / P14175 glycine betaine ABC transporter ATP binding subunit ProV (EC 7.6.2.9) from Escherichia coli (strain K12) (see 6 papers)
PROV_ECOLI / P14175 Glycine betaine/proline betaine transport system ATP-binding protein ProV from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.12.1 / P14175 ProV aka B2677, component of Glycine betaine/proline porter, ProU or ProVWX (also transports proline betaine, carnitine, dimethyl proline, homobetaine, γ-butyrobetaine and choline with low affinity) from Escherichia coli (see 6 papers)
proV / GB|AAC75724.1 glycine betaine/l-proline transport atp-binding protein prov from Escherichia coli K12 (see 6 papers)
    47% identity, 97% coverage of query (375 bits)

PROV_SALTY / P17328 Glycine betaine/proline betaine transport system ATP-binding protein ProV from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    49% identity, 93% coverage of query (374 bits)

OUSV_DICD3 / E0SCY1 Glycine betaine/choline transport system ATP-binding protein OusV from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    48% identity, 93% coverage of query (369 bits)

A0A077T7Z1 ABC-type quaternary amine transporter (subunit 1/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
    48% identity, 94% coverage of query (361 bits)

TMOW_PELUB / Q4FL37 Trimethylamine N-oxide transport system ATP-binding protein TmoW; TMAO transport system ATP-binding protein TmoW; EC 7.6.2.9 from Pelagibacter ubique (strain HTCC1062) (see paper)
    48% identity, 78% coverage of query (297 bits)

OPUBA_BACSU / Q45460 Choline transport ATP-binding protein OpuBA from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.12.3 / Q45460 OPBA aka OpuBA aka PROV, component of Choline porter from Bacillus subtilis (see 3 papers)
    38% identity, 86% coverage of query (227 bits)

OPUCA_BACSU / O34992 Glycine betaine/carnitine/choline transport ATP-binding protein OpuCA from Bacillus subtilis (strain 168) (see 4 papers)
TC 3.A.1.12.4 / O34992 OPCA aka OpuCA, component of Uptake system for choline, L-carnitine, D-carnitine, glycine betaine, proline betaine, crotonobetaine, γ-butyrobetaine, dimethylsulfonioacetate, dimethylsulfoniopropionate, ectoine and choline-O-sulfate from Bacillus subtilis (see 2 papers)
    38% identity, 86% coverage of query (219 bits)

OPUCA_LISM4 / G2JZ44 Carnitine transport ATP-binding protein OpuCA; EC 7.6.2.9 from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCA_LISMN / Q9KHT9 Carnitine transport ATP-binding protein OpuCA; EC 7.6.2.9 from Listeria monocytogenes (see paper)
    37% identity, 86% coverage of query (218 bits)

TC 3.A.1.12.11 / Q8Q041 Glycine betaine transporter, ATP-binding protein, component of The glycine betaine uptake porter, GbpABCD from Methanosarcina mazei (see paper)
    40% identity, 84% coverage of query (218 bits)

OSMV_SALTY / Q8ZPK4 Osmoprotectant import ATP-binding protein OsmV; EC 7.6.2.- from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.12.14 / Q8ZPK4 ABC-type proline/glycine betaine transport system, component of OsmU (OsmVWXY) transporter for glycine betaine and choline-O-sulfate uptake. Induced by osmotic stress (0.3M NaCl) (Frossard et al., 2012). Also called OpuCA/CB1/CB2/CC from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    38% identity, 73% coverage of query (197 bits)

YehX / b2129 glycine betaine ABC transporter ATP binding subunit YehX from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yehX / P33360 glycine betaine ABC transporter ATP binding subunit YehX from Escherichia coli (strain K12) (see 3 papers)
YEHX_ECOLI / P33360 Glycine betaine uptake system ATP-binding protein YehX; EC 7.4.2.- from Escherichia coli (strain K12) (see 2 papers)
    38% identity, 73% coverage of query (187 bits)

Build an alignment

Build an alignment for 351279 and 17 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

SapD / b1291 putrescine ABC exporter ATP binding protein SapD (EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
SapD / P0AAH4 putrescine ABC exporter ATP binding protein SapD (EC 7.6.2.16) from Escherichia coli (strain K12) (see 5 papers)
SAPD_ECOLI / P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see 2 papers)
    28% identity, 73% coverage of query (100 bits)

ABCA2_HUMAN / Q9BZC7 ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette 2; EC 7.6.2.- from Homo sapiens (Human) (see 10 papers)
    24% identity, 70% coverage of query (82.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory