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Searching for up to 100 curated homologs for 351285 FitnessBrowser__Btheta:351285 (295 a.a.)

Found high-coverage hits (≥70%) to 68 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

C4M2I2 fructokinase (EC 2.7.1.4) from Entamoeba histolytica (see paper)
    46% identity, 96% coverage of query (245 bits)

Echvi_2804 Fructokinase (EC 2.7.1.4) from Echinicola vietnamensis KMM 6221, DSM 17526
    31% identity, 96% coverage of query (139 bits)

G4T023 fructokinase (EC 2.7.1.4) from Methylotuvimicrobium alcaliphilum (see paper)
    30% identity, 98% coverage of query (105 bits)

PFKB_THETC / D9TT10 ATP-dependent 6-phosphofructokinase; ATP-PFK; Phosphofructokinase; EC 2.7.1.11 from Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032) (Clostridium thermosaccharolyticum) (see paper)
    30% identity, 92% coverage of query (100 bits)

scrK / GB|AAA08602.1 fructokinase; EC 2.7.1.4 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
scrK / CAA43323.1 fructokinase from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    30% identity, 97% coverage of query (95.5 bits)

Build an alignment

Build an alignment for 351285 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q8NQR0 ribokinase (EC 2.7.1.15) from Corynebacterium glutamicum (see paper)
    27% identity, 92% coverage of query (94.7 bits)

Q9LNE4 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    27% identity, 97% coverage of query (90.9 bits)

Q9M1B9 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    27% identity, 97% coverage of query (88.6 bits)

Q9SID0 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    28% identity, 96% coverage of query (87.0 bits)

scrK / P26420 fructokinase (EC 2.7.1.4) from Klebsiella pneumoniae (see paper)
SCRK_KLEPN / P26420 Fructokinase; EC 2.7.1.4 from Klebsiella pneumoniae (see paper)
scrK / GB|CAA43322.1 fructokinase; EC 2.7.1.4 from Klebsiella pneumoniae (see paper)
scrK / CAA43322.1 fructokinase from Klebsiella pneumoniae (see paper)
    29% identity, 97% coverage of query (86.7 bits)

Q42645 fructokinase (EC 2.7.1.4) from Beta vulgaris (see paper)
    27% identity, 97% coverage of query (85.9 bits)

O82616 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    27% identity, 97% coverage of query (85.1 bits)

A0A0H3AER7 fructokinase (EC 2.7.1.4) from Vibrio cholerae (see paper)
    26% identity, 95% coverage of query (83.2 bits)

5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
    26% identity, 95% coverage of query (83.2 bits)

Q42896 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    27% identity, 97% coverage of query (82.0 bits)

O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    27% identity, 97% coverage of query (80.9 bits)

SCRK2_MAIZE / Q6XZ78 Fructokinase-2; ZmFRK2; EC 2.7.1.4 from Zea mays (Maize)
    26% identity, 98% coverage of query (80.1 bits)

Q9FLH8 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    27% identity, 96% coverage of query (80.1 bits)

P37829 fructokinase (EC 2.7.1.4) from Solanum tuberosum (see 2 papers)
    27% identity, 97% coverage of query (79.7 bits)

3ih0A / O59128 Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with amp-pnp
    27% identity, 86% coverage of query (79.3 bits)

5yggA / A0A0H3AER7 Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
    26% identity, 95% coverage of query (79.0 bits)

3gbuA Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with atp
    28% identity, 86% coverage of query (79.0 bits)

SCRK1_MAIZE / Q6XZ79 Fructokinase-1; ZmFRK1; EC 2.7.1.4 from Zea mays (Maize)
    27% identity, 97% coverage of query (78.2 bits)

SCRK1_ORYSJ / Q0JGZ6 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
    26% identity, 97% coverage of query (77.0 bits)

SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
    26% identity, 97% coverage of query (77.0 bits)

cscK / GB|CAA57218.2 fructokinase; EC 2.7.1.4 from Escherichia coli (see paper)
    28% identity, 97% coverage of query (77.0 bits)

AO353_25910 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2E3
    25% identity, 95% coverage of query (76.6 bits)

Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    27% identity, 96% coverage of query (72.8 bits)

SCRK2_ORYSI / A2YQL4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
SCRK2_ORYSJ / Q0J8G4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
A2YQL4 fructokinase (EC 2.7.1.4) from Oryza sativa (see paper)
    26% identity, 97% coverage of query (72.4 bits)

Shewana3_0069 Fructokinase (EC 2.7.1.4) from Shewanella sp. ANA-3
    24% identity, 97% coverage of query (71.6 bits)

Pf6N2E2_1965 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2E2
    27% identity, 94% coverage of query (69.3 bits)

AO356_00035 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2C3
    27% identity, 94% coverage of query (68.6 bits)

6ilsB / A1A6H3 Structure of arabidopsis thaliana ribokinase complexed with ribose and atp (see paper)
    27% identity, 90% coverage of query (67.4 bits)

PfGW456L13_3036 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens GW456-L13
    26% identity, 95% coverage of query (67.4 bits)

scrK / Q9ZHJ6 fructokinase (EC 2.7.1.4) from Clostridium beijerinckii (see paper)
    25% identity, 98% coverage of query (66.6 bits)

RBSK / A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see 2 papers)
RBSK_ARATH / A1A6H3 Ribokinase; AtRBSK; RK; EC 2.7.1.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see paper)
    27% identity, 90% coverage of query (66.2 bits)

FRLD_BACSU / O32153 Fructosamine kinase FrlD; EC 2.7.1.- from Bacillus subtilis (strain 168) (see paper)
O32153 fructoselysine 6-kinase (EC 2.7.1.218) from Bacillus subtilis (see paper)
    26% identity, 92% coverage of query (64.7 bits)

STM4066 / Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
AIRSK_SALTY / Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
    25% identity, 97% coverage of query (63.5 bits)

RR42_RS28860 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus basilensis FW507-4G11
    25% identity, 98% coverage of query (62.4 bits)

4wjmA / Q2YNY7 Crystal structure of fructokinase from brucella abortus 2308 with bound amppnp
    24% identity, 95% coverage of query (59.7 bits)

Dshi_2797 Fructokinase (EC 2.7.1.4) from Dinoroseobacter shibae DFL-12
    25% identity, 96% coverage of query (59.7 bits)

1tz3A / Q8ZKR2 Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
    24% identity, 97% coverage of query (59.7 bits)

1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog
    24% identity, 97% coverage of query (59.7 bits)

KDGK1_HALVD / D4GSE6 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxygluconate/2-keto-3-deoxygalactonate kinase; KDG kinase; KDGK-1; EC 2.7.1.178 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GSE6 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Haloferax volcanii (see paper)
    24% identity, 88% coverage of query (59.3 bits)

KDGK_THETE / Q704D0 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermoproteus tenax (see paper)
kdgK / CAF18464.1 2-Keto-3-deoxy-gluconate kinase from Thermoproteus tenax (see paper)
    26% identity, 91% coverage of query (57.8 bits)

frk / GB|AAB52373.1 fructokinase; EC 2.7.1.4 from Rhizobium leguminosarum bv. trifolii (see paper)
    25% identity, 86% coverage of query (57.4 bits)

2varA / Q97U29 Crystal structure of sulfolobus solfataricus 2-keto-3-deoxygluconate kinase complexed with 2-keto-3-deoxygluconate (see paper)
    23% identity, 89% coverage of query (56.6 bits)

kdgK / Q97U29 2-dehydro-3-deoxyglucono/2-dehydro-3-deoxygalactonokinase monomer (EC 2.7.1.178) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see 3 papers)
KDGK_SACS2 / Q97U29 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxy-galactonokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; KDGal kinase; EC 2.7.1.178 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
Q97U29 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178) from Saccharolobus solfataricus (see 5 papers)
    23% identity, 89% coverage of query (56.6 bits)

5c41A / Q9H477 Crystal structure of human ribokinase in complex with amppcp in p21 spacegroup and with 4 protomers
    27% identity, 78% coverage of query (53.1 bits)

7fcaD / B2HEF4 Pfkb(mycobacterium marinum) (see paper)
    26% identity, 83% coverage of query (53.1 bits)

2fv7A Crystal structure of human ribokinase
    27% identity, 78% coverage of query (53.1 bits)

6wk0B Crystal structure of human ribokinase in complex with amppcp and ribose
    27% identity, 78% coverage of query (53.1 bits)

5c3yA Structure of human ribokinase crystallized with amppnp
    27% identity, 78% coverage of query (53.1 bits)

RBSK_HUMAN / Q9H477 Ribokinase; RK; EC 2.7.1.15 from Homo sapiens (Human) (see paper)
Q9H477 ribokinase (EC 2.7.1.15) from Homo sapiens (see paper)
    27% identity, 78% coverage of query (52.8 bits)

5byfA Crystal structure of human ribokinase in complex with amp
    27% identity, 78% coverage of query (52.8 bits)

6wjzA Crystal structure of human ribokinase in complex with ampcp
    27% identity, 78% coverage of query (52.8 bits)

BPHYT_RS13910 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Burkholderia phytofirmans PsJN
    24% identity, 95% coverage of query (52.4 bits)

6xk2A / J9VQ51 Crystal structure of ribokinase from cryptococcus neoformans var. Grubii serotype a in complex with adp
    27% identity, 93% coverage of query (52.4 bits)

kdgK / P45416 2-dehydro-3-deoxy-D-gluconate kinase (EC 2.7.1.178) from Dickeya dadantii (strain 3937) (see 2 papers)
KDGK_DICD3 / P45416 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    25% identity, 97% coverage of query (51.2 bits)

Q5DKU6 adenosine kinase (EC 2.7.1.20) from Nicotiana tabacum (see paper)
    25% identity, 90% coverage of query (50.4 bits)

AO356_00950 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2C3
    24% identity, 91% coverage of query (50.1 bits)

Q5DKU8 adenosine kinase (EC 2.7.1.20) from Nicotiana tabacum (see paper)
    24% identity, 90% coverage of query (49.7 bits)

Q5DKU9 adenosine kinase (EC 2.7.1.20) from Nicotiana tabacum (see paper)
    24% identity, 90% coverage of query (49.3 bits)

2c49A / Q57849 Crystal structure of methanocaldococcus jannaschii nucleoside kinase - an archaeal member of the ribokinase family (see paper)
    23% identity, 93% coverage of query (48.5 bits)

NK_METJA / Q57849 Nucleoside kinase; NK; ATP-dependent nucleoside monophosphokinase; Cytidine kinase; Guanosine-inosine kinase; EC 2.7.1.213; EC 2.7.1.73 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
    23% identity, 93% coverage of query (48.5 bits)

Q5DKV0 adenosine kinase (EC 2.7.1.20) from Nicotiana tabacum (see paper)
    24% identity, 90% coverage of query (46.2 bits)

Q9YG89 6-phosphofructokinase (EC 2.7.1.11) from Aeropyrum pernix (see 2 papers)
    22% identity, 90% coverage of query (46.2 bits)

3in1A / P77493 Crystal structure of a putative ribokinase in complex with adp from e.Coli
    22% identity, 88% coverage of query (44.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory