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Searching for up to 100 curated homologs for 351507 FitnessBrowser__Btheta:351507 (299 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DAPDH_BACFN / Q5L9Q6 Meso-diaminopimelate D-dehydrogenase; DAPDH; Meso-DAP dehydrogenase; EC 1.4.1.16 from Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) (see paper)
    95% identity, 100% coverage of query (584 bits)

Q64PZ8 diaminopimelate dehydrogenase (EC 1.4.1.16) from Bacteroides fragilis (see paper)
    95% identity, 100% coverage of query (583 bits)

8hp3A / A0A2K0XCZ3 Crystal structure of meso-diaminopimelate dehydrogenase from prevotella timonensis (see paper)
    71% identity, 100% coverage of query (443 bits)

Q7MW40 diaminopimelate dehydrogenase (EC 1.4.1.16) from Porphyromonas gingivalis (see 3 papers)
    70% identity, 99% coverage of query (433 bits)

A0A1M5M5H3 diaminopimelate dehydrogenase (EC 1.4.1.16) from Thermosyntropha lipolytica (see paper)
    67% identity, 100% coverage of query (420 bits)

Q67PI3 diaminopimelate dehydrogenase (EC 1.4.1.16) from Symbiobacterium thermophilum (see 7 papers)
    66% identity, 100% coverage of query (413 bits)

3wbbA / Q67PI3 Crystal structures of meso-diaminopimelate dehydrogenase from symbiobacterium thermophilum (see paper)
    66% identity, 99% coverage of query (411 bits)

3wbfA Crystal structure of meso-diaminopimelate dehydrogenase from symbiobacterium thermophilum co-crystallized with NADP+ and dap
    66% identity, 99% coverage of query (411 bits)

8i7hA Meso-diaminopimelate dehydrogenase
    65% identity, 99% coverage of query (409 bits)

F7YTT4 diaminopimelate dehydrogenase (EC 1.4.1.16) from Pseudothermotoga thermarum (see paper)
    56% identity, 100% coverage of query (344 bits)

dapdh / Q9KWR0 meso-diaminopimelate dehydrogenase subunit (EC 1.4.1.16) from Lysinibacillus sphaericus (see 2 papers)
DAPDH_LYSSH / Q9KWR0 Meso-diaminopimelate D-dehydrogenase; DAPDH; Meso-DAP dehydrogenase; Meso-alpha,epsilon-diaminopimelate D-dehydrogenase; EC 1.4.1.16 from Lysinibacillus sphaericus (Bacillus sphaericus) (see 2 papers)
Q9KWR0 diaminopimelate dehydrogenase (EC 1.4.1.16) from Lysinibacillus sphaericus (see paper)
    34% identity, 96% coverage of query (150 bits)

DAPDH_URETH / G1UII1 Meso-diaminopimelate D-dehydrogenase; DAPDH; Meso-DAP dehydrogenase; EC 1.4.1.16 from Ureibacillus thermosphaericus (see paper)
G1UII1 diaminopimelate dehydrogenase (EC 1.4.1.16) from Ureibacillus thermosphaericus (see 3 papers)
    33% identity, 98% coverage of query (147 bits)

3wycA / G1UII1 Structure of a meso-diaminopimelate dehydrogenase in complex with nadp (see paper)
    33% identity, 97% coverage of query (144 bits)

DAPDH_ACET2 / A3DDX7 Meso-diaminopimelate D-dehydrogenase; DAPDH; Meso-DAP dehydrogenase; EC 1.4.1.16 from Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Clostridium thermocellum) (see paper)
A3DDX7 diaminopimelate dehydrogenase (EC 1.4.1.16) from Acetivibrio thermocellus (see paper)
    31% identity, 98% coverage of query (136 bits)

Q890V3 diaminopimelate dehydrogenase (EC 1.4.1.16) from Clostridium tetani (see paper)
    32% identity, 97% coverage of query (135 bits)

3wgyB / Q890V3 Crystal structure of meso-dapdh q154l/t173i/r199m/p248s/h249n/n276s mutant with 4-methyl-2-oxovalerate of from clostridium tetani e88
    31% identity, 97% coverage of query (129 bits)

3wgqA Crystal structure of meso-dapdh q154l/t173i/r199m/p248s/h249n/n276s mutant with dap of from clostridium tetani e88
    31% identity, 97% coverage of query (129 bits)

3wgzB Crystal structure of meso-dapdh q154l/t173i/r199m/p248s/h249n/n276s mutant with d-leucine of from clostridium tetani e88
    31% identity, 97% coverage of query (129 bits)

ddh / P04964 meso-diaminopimelate D-dehydrogenase subunit (EC 1.4.1.16) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 4 papers)
DAPDH_CORGL / P04964 Meso-diaminopimelate D-dehydrogenase; DAPDH; Meso-DAP dehydrogenase; EC 1.4.1.16 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 4 papers)
1dapA / P04964 C. Glutamicum dap dehydrogenase in complex with NADP+ (see paper)
    30% identity, 99% coverage of query (122 bits)

3dapB C. Glutamicum dap dehydrogenase in complex with NADP+ and the inhibitor 5s-isoxazoline
    30% identity, 99% coverage of query (122 bits)

2dapA C. Glutamicum dap dehydrogenase in complex with dap
    30% identity, 99% coverage of query (122 bits)

1f06B Three dimensional structure of the ternary complex of corynebacterium glutamicum diaminopimelate dehydrogenase NADPH-l-2-amino-6-methylene- pimelate
    30% identity, 99% coverage of query (122 bits)

1dapB C. Glutamicum dap dehydrogenase in complex with NADP+
    30% identity, 99% coverage of query (122 bits)

5gz6A Structure of d-amino acid dehydrogenase in complex with NADPH and 2- keto-6-aminocapronic acid
    31% identity, 97% coverage of query (120 bits)

Build an alignment

Build an alignment for 351507 and 24 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

5loaA Crystal structure of the engineered d-amino acid dehydrogenase (daadh) bound to NADP+
    28% identity, 98% coverage of query (113 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory