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Searching for up to 100 curated homologs for 351619 FitnessBrowser__Btheta:351619 (633 a.a.)

Found high-coverage hits (≥70%) to 16 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Caur_2509 / A9WI24 methylmalonyl-CoA mutase small subunit (EC 5.4.99.2) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
    32% identity, 98% coverage of query (296 bits)

mutA / AAA03040.1 methylmalonyl-CoA small subunit from Streptomyces cinnamonensis (see paper)
    32% identity, 93% coverage of query (260 bits)

Q6TMA2 methylmalonyl-CoA mutase (EC 5.4.99.2) from Methylorubrum extorquens (see paper)
    31% identity, 97% coverage of query (226 bits)

Build an alignment

Build an alignment for 351619 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

mcmA / Q3J4D7 methylmalonyl-CoA mutase (EC 5.4.99.2) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see paper)
MCM_CERS4 / Q3J4D7 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter sphaeroides) (see 2 papers)
    29% identity, 72% coverage of query (218 bits)

7reqD / P11652 Methylmalonyl-coa mutase, 2-carboxypropyl-coa inhibitor complex (see paper)
    29% identity, 91% coverage of query (206 bits)

6reqB Methylmalonyl-coa mutase, 3-carboxypropyl-coa inhibitor complex
    29% identity, 91% coverage of query (206 bits)

5reqD Methylmalonyl-coa mutase, y89f mutant, substrate complex
    29% identity, 91% coverage of query (206 bits)

1e1cB Methylmalonyl-coa mutase h244a mutant
    29% identity, 91% coverage of query (206 bits)

mutA / P11652 methylmalonyl-CoA mutase small subunit (EC 5.4.99.2) from Propionibacterium freudenreichii subsp. shermanii (see 8 papers)
P11652 methylmalonyl-CoA mutase (EC 5.4.99.2) from Propionibacterium freudenreichii subsp. shermanii (see paper)
    29% identity, 91% coverage of query (205 bits)

Caur_2508 / A9WI23 methylmalonyl-CoA mutase large subunit (EC 5.4.99.2) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
    29% identity, 73% coverage of query (201 bits)

MUTA_MOUSE / P16332 Methylmalonyl-CoA mutase, mitochondrial; MCM; Methylmalonyl-CoA isomerase; EC 5.4.99.2 from Mus musculus (Mouse) (see paper)
    28% identity, 72% coverage of query (181 bits)

Q23381 methylmalonyl-CoA mutase (EC 5.4.99.2) from Caenorhabditis elegans (see paper)
    27% identity, 70% coverage of query (180 bits)

Q8MI68 methylmalonyl-CoA mutase (EC 5.4.99.2) from Sus scrofa (see paper)
    28% identity, 71% coverage of query (180 bits)

MUT / P22033 Methylmalonyl-CoA mutase, mitochondrial (EC 5.4.99.2) from Homo sapiens (see 4 papers)
MUTA_HUMAN / P22033 Methylmalonyl-CoA mutase, mitochondrial; MCM; Methylmalonyl-CoA isomerase; EC 5.4.99.2 from Homo sapiens (Human) (see 31 papers)
P22033 methylmalonyl-CoA mutase (EC 5.4.99.2) from Homo sapiens (see 6 papers)
    28% identity, 71% coverage of query (176 bits)

O74009 methylmalonyl-CoA mutase (subunit 2/2) (EC 5.4.99.2) from Pyrococcus horikoshii (see paper)
    25% identity, 75% coverage of query (154 bits)

D5WTR7 2-hydroxyisobutanoyl-CoA mutase (subunit 2/2) (EC 5.4.99.64) from Kyrpidia tusciae DSM 2912 (see paper)
    25% identity, 72% coverage of query (121 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory