Searching for up to 100 curated homologs for 352888 FitnessBrowser__Btheta:352888 (348 a.a.)
Found high-coverage hits (≥70%) to 63 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
3oetH / P60802 D-erythronate-4-phosphate dehydrogenase complexed with NAD
38% identity, 97% coverage of query (243 bits)
5dt9A / Q9KQ92 Crystal structure of a putative d-erythronate-4-phosphate dehydrogenase from vibrio cholerae
35% identity, 99% coverage of query (231 bits)
PdxB / b2320 erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
pdxB / P05459 erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) from Escherichia coli (strain K12) (see 20 papers)
PDXB_ECOLI / P05459 Erythronate-4-phosphate dehydrogenase; EC 1.1.1.290 from Escherichia coli (strain K12) (see 2 papers)
P05459 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) from Escherichia coli (see 3 papers)
37% identity, 99% coverage of query (224 bits)
Q7N2B2 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) from Photorhabdus luminescens (see paper)
39% identity, 99% coverage of query (221 bits)
PDXB_PSEAE / Q9I3W9 Erythronate-4-phosphate dehydrogenase; EC 1.1.1.290 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
Q9I3W9 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) from Pseudomonas aeruginosa (see paper)
2o4cA / Q9I3W9 Crystal structure of d-erythronate-4-phosphate dehydrogenase complexed with NAD (see paper)
33% identity, 97% coverage of query (195 bits)
1wwkA / O50095 Crystal structure of phosphoglycerate dehydrogenase from pyrococcus horikoshii ot3
37% identity, 71% coverage of query (136 bits)
HPR_THEMA / Q9X1C1 Hydroxypyruvate reductase; HPR; EC 1.1.1.81 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
31% identity, 72% coverage of query (132 bits)
GYAR_THELN / Q9C4M5 Glyoxylate reductase; EC 1.1.1.26 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see paper)
Q9C4M5 glyoxylate reductase (EC 1.1.1.26) from Thermococcus litoralis (see paper)
30% identity, 76% coverage of query (126 bits)
O66939 D-lactate dehydrogenase (EC 1.1.1.28) from Aquifex aeolicus (see paper)
3kb6B / O66939 Crystal structure of d-lactate dehydrogenase from aquifex aeolicus complexed with NAD and lactic acid (see paper)
30% identity, 72% coverage of query (121 bits)
Build an alignment for 352888 and 9 homologs with ≥ 30% identity
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Echvi_2777 fused D-3-phosphoglycerate dehydrogenase / phosphoserine phosphatase (EC 1.1.1.95; EC 3.1.3.3) from Echinicola vietnamensis KMM 6221, DSM 17526
27% identity, 77% coverage of query (118 bits)
6biiA / F8AEA4 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) (see paper)
29% identity, 70% coverage of query (114 bits)
F8AEA4 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Pyrococcus yayanosii (see paper)
29% identity, 70% coverage of query (114 bits)
Q972A9 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Sulfurisphaera tokodaii (see paper)
31% identity, 72% coverage of query (110 bits)
2eklA / Q972A9 Structure of st1218 protein from sulfolobus tokodaii
31% identity, 72% coverage of query (110 bits)
5aovA / Q8U3Y2 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate (see paper)
27% identity, 70% coverage of query (109 bits)
Q8U3Y2 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Pyrococcus furiosus (see paper)
27% identity, 70% coverage of query (109 bits)
FLDH_CLOS1 / J7SHB8 Aromatic 2-oxoacid reductase; Indolelactate dehydrogenase; EC 1.1.1.110 from Clostridium sporogenes (strain ATCC 15579) (see 2 papers)
29% identity, 70% coverage of query (107 bits)
fldH / G9EZR6 aromatic 2-oxoacid reductase (EC 1.1.1.110) from Clostridium sporogenes (strain ATCC 7955 / DSM 767 / NBRC 16411 / NCIMB 8053 / NCTC 8594 / PA 3679) (see 6 papers)
FLDH_CLOS3 / G9EZR6 Aromatic 2-oxoacid reductase; Phenyllactate dehydrogenase; EC 1.1.1.110 from Clostridium sporogenes (strain ATCC 7955 / DSM 767 / NBRC 16411 / NCIMB 8053 / NCTC 8594 / PA 3679) (see paper)
29% identity, 70% coverage of query (107 bits)
Q76KF5 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Entamoeba histolytica (see 2 papers)
EhPGDH D-phosphoglycerate dehydrogenase; EC 1.1.1.95 from Entamoeba histolytica HM-1:IMSS (see paper)
29% identity, 80% coverage of query (105 bits)
4njmA / Q76KF5 Crystal structure of phosphoglycerate bound 3-phosphoglycerate dehydrogenase in entamoeba histolytica (see paper)
29% identity, 80% coverage of query (105 bits)
4njoA Crystal structure of cofactor(NAD+) bound 3-phosphoglycerate dehydrogenase in entamoeba histolytica
29% identity, 80% coverage of query (105 bits)
SERA3_ARATH / Q9LT69 D-3-phosphoglycerate dehydrogenase 3, chloroplastic; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LT69 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 4 papers)
27% identity, 75% coverage of query (103 bits)
Q9Z564 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Streptomyces coelicolor (see paper)
26% identity, 74% coverage of query (102 bits)
LDHD_PEDAC / Q59642 D-lactate/D-glycerate dehydrogenase; D-LDH/GDH; D-specific 2-hydroxyacid dehydrogenase; EC 1.1.1.28; EC 1.1.1.29 from Pediococcus acidilactici (see paper)
ldhD / GI|897794 D-lactate dehydrogenase; EC 1.1.1.28; EC 1.1.1.81 from Pediococcus acidilactici (see paper)
24% identity, 79% coverage of query (100 bits)
E0NDE9 D-lactate dehydrogenase (EC 1.1.1.28) from Pediococcus acidilactici (see paper)
24% identity, 79% coverage of query (100 bits)
A0A2R6X868 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Marchantia polymorpha (see paper)
27% identity, 74% coverage of query (100 bits)
PGDH1 / A2DLU8 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Trichomonas vaginalis (strain ATCC PRA-98 / G3) (see paper)
28% identity, 75% coverage of query (100 bits)
2dbqA / O58320 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) (see paper)
27% identity, 80% coverage of query (100 bits)
O58320 Glyoxylate reductase; EC 1.1.1.26 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
27% identity, 80% coverage of query (100 bits)
A0A1Z4EAX4 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Beta vulgaris (see paper)
26% identity, 75% coverage of query (98.2 bits)
HGDH_ACIFV / D2RJU7 (R)-2-hydroxyglutarate dehydrogenase; HGDH; EC 1.1.1.399 from Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) (see paper)
27% identity, 70% coverage of query (97.8 bits)
4xkjA / A0A0M3KL04 A novel d-lactate dehydrogenase from sporolactobacillus sp
29% identity, 71% coverage of query (96.3 bits)
A0A0M3KL04 D-lactate dehydrogenase (EC 1.1.1.28) from Sporolactobacillus inulinus (see paper)
29% identity, 71% coverage of query (95.9 bits)
hprA / P36234 hydroxypyruvate reductase subunit (EC 1.1.1.81) from Hyphomicrobium methylovorum (see paper)
28% identity, 71% coverage of query (95.5 bits)
O83080 D-lactate dehydrogenase (EC 1.1.1.28) from Treponema pallidum (see paper)
24% identity, 77% coverage of query (95.1 bits)
P87228 Putative D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
28% identity, 71% coverage of query (93.6 bits)
kguD / Q5TM04 2-dehydro-6-phosphogluconate reductase (EC 1.1.1.43) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see 2 papers)
26% identity, 76% coverage of query (93.2 bits)
BPHYT_RS11290 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) from Burkholderia phytofirmans PsJN
28% identity, 73% coverage of query (93.2 bits)
P9WNX3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Mycobacterium tuberculosis (see 5 papers)
27% identity, 76% coverage of query (91.7 bits)
O58256 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pyrococcus horikoshii (see paper)
26% identity, 76% coverage of query (91.7 bits)
3dc2A / P9WNX3 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis (see paper)
27% identity, 76% coverage of query (91.3 bits)
3ddnB Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis
27% identity, 76% coverage of query (91.3 bits)
HPR_BLAHS / C0CMQ8 Hydroxypyruvate reductase; EC 1.1.1.81 from Blautia hydrogenotrophica (strain DSM 10507 / JCM 14656 / S5a33) (Ruminococcus hydrogenotrophicus) (see paper)
27% identity, 70% coverage of query (90.5 bits)
ldhA / Q188H7 4-methyl-2-oxopentanoate reductase (EC 1.1.1.345) from Clostridioides difficile (strain 630) (see 2 papers)
ldhA / GI|115249400 (R)-2-hydroxyisocaproate dehydrogenase from Clostridium difficile 630 (see paper)
28% identity, 79% coverage of query (89.4 bits)
3wr5A / Q76EB7 Structural basis on the efficient co2 reduction of acidophilic formate dehydrogenase
26% identity, 73% coverage of query (87.0 bits)
2gcgA / Q9UBQ7 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase (see paper)
28% identity, 74% coverage of query (86.7 bits)
GRHPR / Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.81; EC 1.1.1.79) from Homo sapiens (see 2 papers)
GRHPR_HUMAN / Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) (see 4 papers)
Q9UBQ7 glyoxylate reductase (EC 1.1.1.26); glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Homo sapiens (see 2 papers)
28% identity, 74% coverage of query (86.7 bits)
LDHD_LACDA / P26297 D-lactate dehydrogenase; D-LDH; D-specific 2-hydroxyacid dehydrogenase; EC 1.1.1.28 from Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 / WDCM 00102 / Lb 14) (see paper)
ldhA / OMNI|NTL01LD0096 D-lactate dehydrogenase; EC 1.1.1.28 from Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 (see 3 papers)
23% identity, 78% coverage of query (84.7 bits)
2yq5C / Q1GAA2 Crystal structure of d-isomer specific 2-hydroxyacid dehydrogenase from lactobacillus delbrueckii ssp. Bulgaricus: NAD complexed form (see paper)
25% identity, 76% coverage of query (83.2 bits)
1j49A / P26297 Insights into domain closure, substrate specificity and catalysis of d-lactate dehydrogenase from lactobacillus bulgaricus (see paper)
23% identity, 78% coverage of query (83.2 bits)
6jujA Crystal structure of formate dehydrogenase mutant v198i/c256i/p260s/e261p/s381n/s383f from pseudomonas sp. 101in complex with non-natural cofactor nicotinamide cytosine dinucleotide
26% identity, 73% coverage of query (81.6 bits)
FDH_PSESR / P33160 Formate dehydrogenase; FDH; NAD-dependent formate dehydrogenase; EC 1.17.1.9 from Pseudomonas sp. (strain 101) (Achromobacter parvulus T1) (see 2 papers)
P33160 formate dehydrogenase (EC 1.17.1.9) from Pseudomonas sp. 101 (see paper)
26% identity, 73% coverage of query (81.6 bits)
2nadA High resolution structures of holo and apo formate dehydrogenase
26% identity, 73% coverage of query (81.3 bits)
P30901 D-lactate dehydrogenase (EC 1.1.1.28) from Lactobacillus helveticus (see paper)
2dldA / P30901 D-lactate dehydrogenase complexed with nadh and oxamate
GB|CAA47255.1 D-lactate dehydrogenase; EC 1.1.1.28 from Lactobacillus helveticus (see 2 papers)
21% identity, 85% coverage of query (80.1 bits)
P30901 D-lactate dehydrogenase; D-LDH; D-specific 2-hydroxyacid dehydrogenase; EC 1.1.1.28 from Lactobacillus helveticus (Lactobacillus suntoryeus)
21% identity, 85% coverage of query (80.1 bits)
7arzA / A9SQZ2 Ternary complex of NAD-dependent formate dehydrogenase from physcomitrium patens
25% identity, 73% coverage of query (75.9 bits)
FDH1 / O13437 formate dehydrogenase (EC 1.17.1.9) from Candida boidinii (see 3 papers)
FDH_CANBO / O13437 Formate dehydrogenase; FDH; NAD-dependent formate dehydrogenase; EC 1.17.1.9 from Candida boidinii (Yeast) (see 6 papers)
O13437 formate dehydrogenase (EC 1.17.1.9) from [Candida] boidinii (see 12 papers)
fdh3 / CAB54834.1 formate dehydrogenase from [Candida] boidinii (see paper)
26% identity, 70% coverage of query (73.2 bits)
6t8zAAA Formate dehydrogenase
27% identity, 75% coverage of query (72.4 bits)
6t8yBBB / G0SGU4 6t8yBBB (see paper)
27% identity, 75% coverage of query (72.4 bits)
6d4bA / A0A0A1EQY0 Crystal structure of candida boidinii formate dehydrogenase v123a mutant complexed with NAD+ and azide
25% identity, 72% coverage of query (71.2 bits)
8j3oA Formate dehydrogenase wild-type enzyme from candida dubliniensis complexed with nadh
24% identity, 72% coverage of query (58.5 bits)
8j3oB Formate dehydrogenase wild-type enzyme from candida dubliniensis complexed with nadh
24% identity, 72% coverage of query (58.5 bits)
6p2iA Acyclic imino acid reductase (bsp5) in complex with NADPH and d-arg (see paper)
27% identity, 76% coverage of query (48.5 bits)
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