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Searching for up to 100 curated homologs for 3607127 Dshi_0549 binding-protein-dependent transport systems inner membrane component (RefSeq) (272 a.a.)

Found high-coverage hits (≥70%) to 54 curated proteins.

Removed hits that are identical to the query, leaving 53

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

mtlG / Q4KC55 polyol ABC-type transporter permease component MtlG from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    44% identity, 92% coverage of query (205 bits)

TC 3.A.1.1.49 / O30493 MtlG, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
    43% identity, 92% coverage of query (203 bits)

PS417_12705 ABC transporter for D-Mannitol and D-Sorbitol, permease component 1 from Pseudomonas simiae WCS417
    43% identity, 92% coverage of query (202 bits)

AO356_00015 ABC transporter for D-Sorbitol, permease component 1 from Pseudomonas fluorescens FW300-N2C3
    41% identity, 92% coverage of query (196 bits)

Pf6N2E2_1961 ABC transporter for D-sorbitol, permease component 2 from Pseudomonas fluorescens FW300-N2E2
    41% identity, 92% coverage of query (195 bits)

SM_b21105 ABC transporter for L-Fucose, permease component 2 from Sinorhizobium meliloti 1021
    34% identity, 97% coverage of query (171 bits)

TC 3.A.1.1.5 / O30833 SmoG, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) (see paper)
    37% identity, 92% coverage of query (167 bits)

PGA1_c13190 ABC transporter for D-Sorbitol, permease component 1 from Phaeobacter inhibens BS107
    35% identity, 92% coverage of query (164 bits)

Pf1N1B4_5114 sucrose ABC transporter, permease component 2 from Pseudomonas fluorescens FW300-N1B4
    34% identity, 96% coverage of query (162 bits)

HSERO_RS17010 ABC transporter for D-sorbitol/xylitol, permease component 2 from Herbaspirillum seropedicae SmR1
    36% identity, 91% coverage of query (161 bits)

TC 3.A.1.1.12 / Q9AI66 PalG, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
    35% identity, 97% coverage of query (161 bits)

Ac3H11_2942 ABC transporter for D-Sorbitol, permease component 1 from Acidovorax sp. GW101-3H11
    35% identity, 92% coverage of query (160 bits)

TC 3.A.1.1.25 / Q72H66 Maltose transport system permease protein malG aka TT_C1629, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    38% identity, 92% coverage of query (160 bits)

BPHYT_RS16105 ABC transporter for D-Sorbitol, permease component 1 from Burkholderia phytofirmans PsJN
    35% identity, 94% coverage of query (160 bits)

TC 3.A.1.1.41 / G4FGN6 ABC-type transporter, integral membrane subunit, component of Trehalose porter. Also binds sucrose (Boucher and Noll, 2011). Induced by glucose and trehalose. Directly regulated by trehalose-responsive regulator TreR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    33% identity, 99% coverage of query (155 bits)

sugB / P9WG01 ABC-type trehalose transporter integral membrane protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGB_MYCTU / P9WG01 Trehalose transport system permease protein SugB from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
TC 3.A.1.1.31 / O50453 PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGB, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 3 papers)
    38% identity, 96% coverage of query (152 bits)

Ac3H11_794 ABC transporter for Glycerol, permease component 2 from Acidovorax sp. GW101-3H11
    33% identity, 98% coverage of query (150 bits)

SM_b20327 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 2 (ThuG) from Sinorhizobium meliloti 1021
TC 3.A.1.1.17 / Q9R9Q5 ThuG aka RB0313 aka SMB20327, component of Trehalose/maltose/sucrose porter (trehalose inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 3 papers)
    34% identity, 96% coverage of query (147 bits)

DASC_STRCO / Q9K489 Diacetylchitobiose uptake system permease protein DasC from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    31% identity, 99% coverage of query (139 bits)

TC 3.A.1.1.35 / G3LHZ1 GlpQ, component of Glycerol uptake porter, GlpSTPQV from Rhizobium leguminosarum bv. viciae
    34% identity, 92% coverage of query (137 bits)

MALG_THELN / Q7LYX6 Trehalose/maltose transport system permease protein MalG from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 3 papers)
TC 3.A.1.1.7 / O51925 MalG aka PF1741, component of Maltose/trehalose porter (see paper)
    34% identity, 95% coverage of query (137 bits)

TC 3.A.1.1.33 / Q8KN17 Putative sugar transporter integral membrane protein, component of The N,N'-diacetylchitobiose uptake transporter, DasABC/MsiK (MsiK energizes several ABC transporters (see 3.A.1.1.23)) from Streptomyces sp. 139 (see 2 papers)
    30% identity, 99% coverage of query (134 bits)

TC 3.A.1.1.18 / Q8RJU8 NgcG, component of N-Acetylglucosamine/N,N'-diacetyl chitobiose porter (NgcK (C) not identified) from Streptomyces olivaceoviridis (Streptomyces corchorusii) (see paper)
    33% identity, 98% coverage of query (133 bits)

TC 3.A.1.1.44 / Q9KZ08 Putative maltose permease, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    31% identity, 96% coverage of query (128 bits)

smoH / Q7CS31 ABC-type 3-(6-sulfo-α-D-quinovosyl)-sn-glycerol transporter permease subunit from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
    31% identity, 92% coverage of query (122 bits)

NGCG_STRCO / O50501 Diacetylchitobiose uptake system permease protein NgcG from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    32% identity, 85% coverage of query (121 bits)

PGA1_c27950 N-Acetyl-D-glucosamine ABC transport system, permease component 2 from Phaeobacter inhibens BS107
    30% identity, 93% coverage of query (117 bits)

TC 3.A.1.1.24 / Q72KX4 Sugar transport system permease protein aka TT_C0326, component of The glucose/mannose porter TTC0326-8 plus MalK1 (ABC protein, shared with 3.A.1.1.25) from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    30% identity, 96% coverage of query (117 bits)

SMc02871 ABC transporter for N-Acetyl-D-glucosamine, permease protein 2 from Sinorhizobium meliloti 1021
    31% identity, 100% coverage of query (116 bits)

G9MB86 ABC-type glycerol 3-phosphate transporter (subunit 1/3) (EC 7.6.2.10) from Thermus thermophilus (see paper)
    32% identity, 86% coverage of query (114 bits)

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Build an alignment for 3607127 and 30 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

YcjP / b1312 putative ABC transporter membrane subunit YcjP from Escherichia coli K-12 substr. MG1655 (see 2 papers)
TC 3.A.1.1.46 / P77716 Inner membrane ABC transporter permease protein YcjP, component of Probable glucoside uptake porter, YcjNOPV from Escherichia coli (strain K12)
    29% identity, 100% coverage of query (112 bits)

TC 3.A.1.1.6 / Q48397 CymG, component of Cyclodextrin porter from Klebsiella oxytoca (see paper)
    29% identity, 93% coverage of query (108 bits)

SM_b21219 ABC transporter for D-Glucosamine, permease component 1 from Sinorhizobium meliloti 1021
    31% identity, 95% coverage of query (107 bits)

SMc04257 ABC transporter for D-Cellobiose and D-Salicin, permease component 1 from Sinorhizobium meliloti 1021
    29% identity, 95% coverage of query (106 bits)

TC 3.A.1.1.39 / Q9WYR1 Alpha-1,4-digalacturonate porter (Nanavati et al., 2006). Regulated by pectin utilization regulon UxaR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    29% identity, 95% coverage of query (103 bits)

TC 3.A.1.1.38 / Q9WYQ1 Sugar ABC transporter, permease protein, component of Inositol phosphate porter (Rodionova et al. 2013). Binds inositol phosphate with low Kd and inositol with a lower affinity from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    28% identity, 91% coverage of query (102 bits)

TC 3.A.1.1.16 / Q8TZQ0 MalG, component of Maltooligosaccharide porter (Maltose is not a substrate, but maltotriose is.) from Pyrococcus furiosus
    32% identity, 76% coverage of query (99.4 bits)

MELC_BACSU / O34518 Melibiose/raffinose/stachyose import permease protein MelC from Bacillus subtilis (strain 168) (see paper)
    29% identity, 100% coverage of query (97.4 bits)

TC 3.A.1.1.20 / Q7WWQ8 Transmembrane permease MsmG, component of The fructooligosaccharide porter, MsmEFGK from Lactobacillus acidophilus (see 2 papers)
msmG / GI|33149340 transmembrane permease MsmG from Lactobacillus acidophilus (see paper)
    29% identity, 97% coverage of query (97.4 bits)

TC 3.A.1.1.27 / Q8DT26 MalG, component of Maltose/Maltotriose/maltodextrin (up to 7 glucose units) transporters MalXFGK (MsmK (3.A.1.1.28) can probably substitute for MalK; Webb et al., 2008) from Streptococcus mutans (see paper)
    28% identity, 96% coverage of query (97.1 bits)

TC 3.A.1.1.26 / O06991 MalG aka yvdI, component of The maltose porter, MdxEFG and MsmX from Bacillus subtilis (see 2 papers)
    28% identity, 82% coverage of query (97.1 bits)

ARAQ_BACSU / P94530 Arabinooligosaccharides transport system permease protein AraQ from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.1.34 / P94530 L-arabinose transport system permease protein AraQ, component of The arabinosaccharide transporter AraNPQMsmX. Transports α-1,5-arabinooligosaccharides, at least up to four L-arabinosyl units; the key transporter for α-1,5-arabinotriose and α-1,5-arabinotetraose, but not for α-1,5-arabinobiose which is transported by AraE. MsmX is also used by the MdxEFG-MsmX system (3.A.1.1.36) (Ferreira and Sá-Nogueira, 2010). Involved in the uptake of pectin oligosaccharides with either MsmX or YurJ as the ATPase from Bacillus subtilis (see 5 papers)
    28% identity, 92% coverage of query (96.3 bits)

GGTD_SYNY3 / Q55473 Osmoprotective compounds uptake permease protein GgtD from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
TC 3.A.1.1.32 / Q55473 Membrane bound sugar transport protein, component of The glucosylglycerol uptake transporter (functions in osmoprotection and also transports sucrose and trehalose (Mikkat and Hagemann, 2000) (most similar to 3.A.1.1.8) from Synechocystis sp. (strain PCC 6803) (see paper)
    28% identity, 84% coverage of query (94.0 bits)

TC 3.A.1.1.23 / Q9X9R5 CBP protein aka CebG, component of The cellobiose/cellotriose (and possibly higher cellooligosaccharides), CebEFGMsiK [MsiK functions to energize several ABC transporters including those for maltose/maltotriose and trehalose] from Streptomyces reticuli (see paper)
    30% identity, 93% coverage of query (91.7 bits)

GANQ_BACSU / O07011 Galactooligosaccharides transport system permease protein GanQ from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.1.2 / O07011 Putative arabinogalactan oligomer transport system permease protein ganQ, component of The galactooligosaccharide (transports the di, tri and tetrasaccharides) uptake porter GanOPQ (GanSPQ; MalEFG) functioning with the energizing ATPase MsmX (see 3.A.1.1.26) from Bacillus subtilis (see 2 papers)
    29% identity, 99% coverage of query (91.7 bits)

Dshi_1650 glucose/maltose/trehalose/sucrose ABC transporter, permease component 2 from Dinoroseobacter shibae DFL-12
    31% identity, 86% coverage of query (91.3 bits)

Ac3H11_2065 glucose ABC transporter, permease component 2 from Acidovorax sp. GW101-3H11
    28% identity, 96% coverage of query (90.5 bits)

YTCP_BACSU / P53561 Polygalacturonan/rhamnogalacturonan transport system permease protein YtcP from Bacillus subtilis (strain 168) (see paper)
    27% identity, 96% coverage of query (85.9 bits)

PotC / b1124 spermidine preferential ABC transporter membrane subunit PotC (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
PotC / P0AFK6 spermidine preferential ABC transporter membrane subunit PotC (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
POTC_ECOLI / P0AFK6 Spermidine/putrescine transport system permease protein PotC from Escherichia coli (strain K12) (see paper)
TC 3.A.1.11.1 / P0AFK6 Spermidine/putrescine transport system permease protein PotC aka B1124, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 5 papers)
potC spermidine/putrescine ABC transporter, permease protein PotC from Escherichia coli K12 (see paper)
    32% identity, 79% coverage of query (85.9 bits)

TC 3.A.1.1.30 / Q88P36 GtsC (GLcG), component of Glucose porter, GtsABCD from Pseudomonas putida (strain KT2440) (see paper)
    30% identity, 75% coverage of query (85.5 bits)

XACI_HALVD / D4GP37 Xylose/arabinose import permease protein XacI from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    28% identity, 95% coverage of query (85.1 bits)

SMc03063 ABC transporter for D-maltose/D-trehalose/sucrose, permease component 2 (AglG) from Sinorhizobium meliloti 1021
TC 3.A.1.1.8 / Q9Z3R7 AglG aka R00697 aka SMC03063, component of Sucrose/maltose/trehalose porter (sucrose-inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
    30% identity, 82% coverage of query (83.2 bits)

MalG / b4032 maltose ABC transporter membrane subunit MalG (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
MalG / P68183 maltose ABC transporter membrane subunit MalG (EC 7.5.2.1) from Escherichia coli (strain K12) (see 6 papers)
MALG_ECOLI / P68183 Maltose/maltodextrin transport system permease protein MalG from Escherichia coli (strain K12) (see 5 papers)
P68183 ABC-type maltose transporter (subunit 2/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68183 Maltose transport system permease protein MalG aka B4032, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 13 papers)
malG / RF|NP_418456 maltose transport system permease protein malG from Escherichia coli K12 (see 15 papers)
    29% identity, 77% coverage of query (74.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory