Searching for up to 100 curated homologs for 3607861 FitnessBrowser__Dino:3607861 (621 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PGA1_c07250 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Phaeobacter inhibens BS107
78% identity, 99% coverage of query (967 bits)
SMc01166 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Sinorhizobium meliloti 1021
50% identity, 100% coverage of query (554 bits)
HSERO_RS12130 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Herbaspirillum seropedicae SmR1
49% identity, 99% coverage of query (550 bits)
Q9L3I0 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening) (EC 3.7.1.22) from Rhizobium leguminosarum (see paper)
48% identity, 100% coverage of query (537 bits)
iolD / P42415 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase (EC 3.7.1.22) from Bacillus subtilis (strain 168) (see 2 papers)
IOLD_BACSU / P42415 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; THcHDO hydrolase; EC 3.7.1.22 from Bacillus subtilis (strain 168) (see paper)
P42415 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening) (EC 3.7.1.22) from Bacillus subtilis (see paper)
38% identity, 99% coverage of query (434 bits)
Pf6N2E2_517 Epi-inositol hydrolase (EC 3.7.1.-) from Pseudomonas fluorescens FW300-N2E2
39% identity, 99% coverage of query (426 bits)
PS417_11870 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas simiae WCS417
39% identity, 99% coverage of query (425 bits)
Pf1N1B4_4279 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas fluorescens FW300-N1B4
39% identity, 99% coverage of query (425 bits)
AO356_23185 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas fluorescens FW300-N2C3
39% identity, 99% coverage of query (423 bits)
AO353_21360 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas fluorescens FW300-N2E3
39% identity, 99% coverage of query (418 bits)
BWI76_RS03090 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Klebsiella michiganensis M5al
37% identity, 99% coverage of query (413 bits)
Build an alignment for 3607861 and 11 homologs with ≥ 30% identity
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Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
26% identity, 93% coverage of query (164 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
25% identity, 92% coverage of query (154 bits)
P42463 acetolactate synthase (EC 2.2.1.6) from Corynebacterium glutamicum (see paper)
26% identity, 91% coverage of query (149 bits)
Q5S3P7 acetolactate synthase (EC 2.2.1.6) from Streptomyces cinnamonensis (see 2 papers)
ilvB / AAV52901.1 acetohydroxy acid synthase large subunit from Streptomyces cinnamonensis (see paper)
27% identity, 91% coverage of query (143 bits)
thzk0150 / BAO66169.1 2-hydroxy-4-methyl-2-(2-phenylacetyl)pentanoic acid synthase from Thermosporothrix hazakensis (see paper)
26% identity, 87% coverage of query (140 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
28% identity, 91% coverage of query (139 bits)
ilvB / AAB38426.1 acetolactate synthase from Mycobacterium avium (see paper)
27% identity, 92% coverage of query (136 bits)
Q5SJ01 acetolactate synthase (EC 2.2.1.6); pyruvate decarboxylase (EC 4.1.1.1) from Thermus thermophilus (see paper)
27% identity, 92% coverage of query (134 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
25% identity, 92% coverage of query (129 bits)
ilvB / AAA93098.1 acetolactate synthase from Streptomyces avermitilis (see paper)
27% identity, 82% coverage of query (129 bits)
P37251 acetolactate synthase (EC 2.2.1.6) from Bacillus subtilis (see paper)
24% identity, 87% coverage of query (127 bits)
xsc / Q93PS3 sulfoacetaldehyde acetyltransferase subunit (EC 2.3.3.15) from Desulfonispora thiosulfatigenes (see 2 papers)
26% identity, 85% coverage of query (126 bits)
SYNPCC7002_A2770 / B1XMM5 2-oxoglutarate decarboxylase monomer (EC 4.1.1.71) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see 2 papers)
B1XMM5 oxoglutarate dehydrogenase (succinyl-transferring) (EC 1.2.4.2) from Synechococcus sp. PCC 7002 (see paper)
24% identity, 92% coverage of query (123 bits)
A5X300 acetolactate synthase (EC 2.2.1.6) from Oryza sativa Indica Group (see paper)
25% identity, 80% coverage of query (116 bits)
Q6K2E8 acetolactate synthase (EC 2.2.1.6) from Oryza sativa (see paper)
25% identity, 80% coverage of query (115 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
24% identity, 81% coverage of query (114 bits)
IlvB / b3671 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ilvB / P08142 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli (strain K12) (see 4 papers)
P08142 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
24% identity, 81% coverage of query (112 bits)
A0A1X9M8K4 sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) from Alkalihalobacillus krulwichiae (see paper)
24% identity, 85% coverage of query (108 bits)
K7TWQ8 acetolactate synthase (EC 2.2.1.6) from Zea mays (see paper)
24% identity, 80% coverage of query (107 bits)
7tzzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase p197t mutant in complex with bispyribac-sodium
23% identity, 81% coverage of query (107 bits)
Q8RL88 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvB / AAL99356.1 acetohydroxy acid synthase large subunit from Geobacillus stearothermophilus (see paper)
22% identity, 83% coverage of query (106 bits)
5k2oA / P17597 Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, pyrithiobac (see paper)
23% identity, 81% coverage of query (106 bits)
xsc / Q84H44 sulfoacetaldehyde acetyltransferase monomer (EC 2.3.3.15) from Castellaniella defragrans (see paper)
XSC_CASDE / Q84H44 Sulfoacetaldehyde acetyltransferase; EC 2.3.3.15 from Castellaniella defragrans (Alcaligenes defragrans) (see paper)
Q84H44 sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) from Castellaniella defragrans (see paper)
26% identity, 77% coverage of query (106 bits)
5k3sA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, bispyribac-sodium
23% identity, 81% coverage of query (106 bits)
8et4A Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
23% identity, 81% coverage of query (106 bits)
5wj1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam
23% identity, 81% coverage of query (106 bits)
5k6tA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, propoxycarbazone-sodium
23% identity, 81% coverage of query (106 bits)
5k6rA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl
23% identity, 81% coverage of query (106 bits)
1z8nA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with an imidazolinone herbicide, imazaquin
23% identity, 81% coverage of query (106 bits)
1yi1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
23% identity, 81% coverage of query (106 bits)
1yi0A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
23% identity, 81% coverage of query (106 bits)
1yhzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
23% identity, 81% coverage of query (106 bits)
1yhyA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
23% identity, 81% coverage of query (106 bits)
1ybhA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide chlorimuron ethyl
23% identity, 81% coverage of query (106 bits)
3ea4A Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron-ester
23% identity, 81% coverage of query (106 bits)
3e9yA Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron
23% identity, 81% coverage of query (106 bits)
ILVB_ARATH / P17597 Acetolactate synthase, chloroplastic; AtALS; Acetohydroxy-acid synthase; Protein CHLORSULFURON RESISTANT 1; EC 2.2.1.6 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
P17597 acetolactate synthase (EC 2.2.1.6) from Arabidopsis thaliana (see 8 papers)
23% identity, 81% coverage of query (105 bits)
A0A0M4NDK0 acetolactate synthase (EC 2.2.1.6) from Poa annua (see paper)
24% identity, 80% coverage of query (105 bits)
A0A0M3TGF7 acetolactate synthase (EC 2.2.1.6) from Poa annua (see paper)
24% identity, 80% coverage of query (104 bits)
als / CAA66718.1 acetolactate synthase from Synechocystis sp (see paper)
24% identity, 87% coverage of query (103 bits)
ilv1 / RF|NP_595382.1 acetolactate synthase catalytic subunit; EC 2.2.1.6 from Schizosaccharomyces pombe (see 2 papers)
23% identity, 80% coverage of query (102 bits)
AT5G17380 / Q9LF46 oxalyl-CoA decarboxylase (EC 4.1.1.8) from Arabidopsis thaliana (see 5 papers)
25% identity, 83% coverage of query (100 bits)
Q0K022 sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) from Cupriavidus necator (see paper)
25% identity, 82% coverage of query (100 bits)
Psest_1181 Glyoxylate carboligase (EC 4.1.1.47) from Pseudomonas stutzeri RCH2
24% identity, 77% coverage of query (99.8 bits)
1t9bA / P07342 Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron (see paper)
22% identity, 87% coverage of query (99.8 bits)
1t9dB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
22% identity, 87% coverage of query (99.4 bits)
1t9bB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
22% identity, 87% coverage of query (98.2 bits)
8beoB Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
25% identity, 77% coverage of query (97.8 bits)
8beoA Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
25% identity, 77% coverage of query (97.8 bits)
5wkcA Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam
22% identity, 87% coverage of query (97.4 bits)
6u9dB / P07342 Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
22% identity, 87% coverage of query (97.1 bits)
ILVB_YEAST / P07342 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; EC 2.2.1.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P07342 acetolactate synthase (EC 2.2.1.6) from Saccharomyces cerevisiae (see 5 papers)
22% identity, 87% coverage of query (96.7 bits)
1t9cA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
22% identity, 87% coverage of query (96.7 bits)
1t9aA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
22% identity, 87% coverage of query (96.7 bits)
1t9dA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
22% identity, 87% coverage of query (96.3 bits)
8i01A / P0AEP7 Crystal structure of escherichia coli glyoxylate carboligase
24% identity, 77% coverage of query (96.3 bits)
1n0hA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorimuron ethyl
22% identity, 87% coverage of query (96.3 bits)
8i07D Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
24% identity, 77% coverage of query (95.5 bits)
8i07A Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
24% identity, 77% coverage of query (95.5 bits)
1powA The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from lactobacillus plantarum
24% identity, 85% coverage of query (93.6 bits)
4feeA High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal b (see paper)
24% identity, 85% coverage of query (93.2 bits)
7egvA / A0A2N1LPC4 Acetolactate synthase from trichoderma harzianum with inhibitor harzianic acid (see paper)
23% identity, 84% coverage of query (93.2 bits)
2ezuA Pyruvate oxidase variant f479w in complex with reaction intermediate 2-acetyl-thiamin diphosphate
24% identity, 85% coverage of query (92.8 bits)
2ez9A Pyruvate oxidase variant f479w in complex with reaction intermediate analogue 2-phosphonolactyl-thiamin diphosphate
24% identity, 85% coverage of query (92.8 bits)
2ez8A Pyruvate oxidase variant f479w in complex with reaction intermediate 2-lactyl-thiamin diphosphate
24% identity, 85% coverage of query (92.8 bits)
2ez4B Pyruvate oxidase variant f479w
24% identity, 85% coverage of query (92.8 bits)
6bd3A Saccharomyces cerevisiae acetohydroxyacid synthase
22% identity, 87% coverage of query (92.4 bits)
1jscA Crystal structure of the catalytic subunit of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors
22% identity, 87% coverage of query (91.7 bits)
6bd9A Saccharomyces cerevisiae acetohydroxyacid synthase
22% identity, 87% coverage of query (90.9 bits)
3ey9A / P07003 Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from escherichia coli (see paper)
23% identity, 79% coverage of query (90.5 bits)
PoxB / b0871 pyruvate oxidase (EC 1.2.5.1) from Escherichia coli K-12 substr. MG1655 (see 70 papers)
poxB / P07003 pyruvate oxidase (EC 1.2.5.1) from Escherichia coli (strain K12) (see 69 papers)
POXB_ECOLI / P07003 Pyruvate dehydrogenase [ubiquinone]; Pyruvate oxidase; POX; Pyruvate:ubiquinone-8 oxidoreductase; EC 1.2.5.1 from Escherichia coli (strain K12) (see 13 papers)
P07003 pyruvate dehydrogenase (quinone) (EC 1.2.5.1) from Escherichia coli (see paper)
23% identity, 79% coverage of query (90.5 bits)
5imsA Saccharomyces cerevisiae acetohydroxyacid synthase
22% identity, 87% coverage of query (90.1 bits)
P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
22% identity, 81% coverage of query (89.7 bits)
6desA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide propoxycarbazone
21% identity, 84% coverage of query (89.7 bits)
6depA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide sulfometuron methyl
21% identity, 84% coverage of query (89.7 bits)
6demA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide bensulfuron methyl
21% identity, 84% coverage of query (89.4 bits)
6delA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide chlorimuron ethyl
21% identity, 84% coverage of query (89.4 bits)
6deoA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron methyl
22% identity, 84% coverage of query (89.4 bits)
6derA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide metosulam
21% identity, 84% coverage of query (89.4 bits)
7pt4A Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with a covalently bound reaction intermediate as well as products formyl-coa and acetone
25% identity, 81% coverage of query (89.0 bits)
7pt4B / P0DUV9 Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with a covalently bound reaction intermediate as well as products formyl-coa and acetone (see paper)
25% identity, 81% coverage of query (89.0 bits)
7pt1A Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with substrate 2-hib-coa and inactive cofactor 3-deaza-thdp
25% identity, 81% coverage of query (88.6 bits)
HACL_ACTC0 / P0DUV9 2-hydroxyacyl-CoA lyase; AcHACL; HACL; 2-hydroxyisobutyryl-CoA lyase; EC 4.1.-.- from Actinomycetospora chiangmaiensis (strain DSM 45062 / JCM 15998 / CCTCC AA 205017 / NBRC 104400 / YIM 0006) (see 2 papers)
25% identity, 81% coverage of query (88.6 bits)
6denA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron ethyl
21% identity, 84% coverage of query (88.6 bits)
P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
23% identity, 81% coverage of query (87.8 bits)
6deqA / A0A1D8PJF9 Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide penoxsulam (see paper)
21% identity, 84% coverage of query (87.4 bits)
6dekA Crystal structure of candida albicans acetohydroxyacid synthase catalytic subunit
21% identity, 84% coverage of query (86.7 bits)
6vz8D / P17597 Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
23% identity, 81% coverage of query (86.3 bits)
2q28A / P0AFI0 Crystal structure of oxalyl-coa decarboxylase from escherichia coli in complex with adenosine-5`-diphosphate (see paper)
24% identity, 81% coverage of query (85.5 bits)
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