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Searching for up to 100 curated homologs for 3608216 Dshi_1621 PfkB domain protein (RefSeq) (316 a.a.)

Found high-coverage hits (≥70%) to 27 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PfkB / b1723 6-phosphofructokinase 2 (EC 2.7.1.11; EC 2.7.1.144) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
pfkB / P06999 6-phosphofructokinase 2 (EC 2.7.1.11; EC 2.7.1.144) from Escherichia coli (strain K12) (see 40 papers)
PFKB_ECOLI / P06999 ATP-dependent 6-phosphofructokinase isozyme 2; ATP-PFK 2; Phosphofructokinase 2; 6-phosphofructokinase isozyme II; Phosphohexokinase 2; EC 2.7.1.11 from Escherichia coli (strain K12) (see 4 papers)
P06999 6-phosphofructokinase (EC 2.7.1.11) from Escherichia coli (see 2 papers)
3n1cA / P06999 Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with fructose-6-phosphate (see paper)
    41% identity, 98% coverage of query (194 bits)

3uqdB Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with substrates and products
    41% identity, 98% coverage of query (194 bits)

3uqdA Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with substrates and products
    41% identity, 98% coverage of query (194 bits)

3uqeA Crystal structure of the phosphofructokinase-2 mutant y23d from escherichia coli
    41% identity, 98% coverage of query (192 bits)

3cqdA Structure of the tetrameric inhibited form of phosphofructokinase-2 from escherichia coli
    41% identity, 98% coverage of query (189 bits)

PFKB_MYCTO / P9WID2 ATP-dependent 6-phosphofructokinase isozyme 2; ATP-PFK 2; Phosphofructokinase 2; Phosphofructokinase B; Phosphohexokinase 2; Tagatose-6-phosphate kinase; EC 2.7.1.11; EC 2.7.1.144 from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) (see paper)
PFKB_MYCTU / P9WID3 ATP-dependent 6-phosphofructokinase isozyme 2; ATP-PFK 2; Phosphofructokinase 2; Phosphofructokinase B; Phosphohexokinase 2; Tagatose-6-phosphate kinase; EC 2.7.1.11; EC 2.7.1.144 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 6 papers)
    35% identity, 98% coverage of query (166 bits)

Psest_3354 1-phosphofructokinase (EC 2.7.1.56) from Pseudomonas stutzeri RCH2
    35% identity, 98% coverage of query (116 bits)

K1PF_VIBCH / Q9KM71 1-phosphofructokinase; Fructose 1-phosphate kinase; Fru1PK; EC 2.7.1.56 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
    30% identity, 85% coverage of query (107 bits)

AO356_07330 1-phosphofructokinase (EC 2.7.1.56) from Pseudomonas fluorescens FW300-N2C3
    34% identity, 92% coverage of query (105 bits)

Build an alignment

Build an alignment for 3608216 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

2f02A / Q833W9 Crystal structure of lacc from enterococcus faecalis in complex with atp
    27% identity, 99% coverage of query (102 bits)

K1PF_XANCP / P23354 1-phosphofructokinase; Fructose 1-phosphate kinase; Fru1PK; EC 2.7.1.56 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
    32% identity, 88% coverage of query (100 bits)

Fpk / b2168 1-phosphofructokinase (EC 2.7.1.56) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
fruK / P0AEW9 1-phosphofructokinase (EC 2.7.1.56) from Escherichia coli (strain K12) (see 8 papers)
K1PF_ECOLI / P0AEW9 1-phosphofructokinase; Fructose 1-phosphate kinase; Fru1PK; EC 2.7.1.56 from Escherichia coli (strain K12) (see paper)
fruK / RF|NP_416673 1-phosphofructokinase from Escherichia coli K12 (see 2 papers)
    31% identity, 89% coverage of query (91.3 bits)

2ajrA / Q9WZT5 Crystal structure of possible 1-phosphofructokinase (ec 2.7.1.56) (tm0828) from thermotoga maritima at 2.46 a resolution
    28% identity, 94% coverage of query (89.7 bits)

lacC / P0A0B8 D-tagatose-6-phosphate kinase subunit (EC 2.7.1.144) from Staphylococcus aureus (strain MW2) (see 2 papers)
P0A0B9 tagatose-6-phosphate kinase (EC 2.7.1.144) from Staphylococcus aureus (see paper)
    28% identity, 86% coverage of query (82.8 bits)

2jg1A / P0A0B9 Structure of staphylococcus aureus d-tagatose-6-phosphate kinase with cofactor and substrate (see paper)
    27% identity, 86% coverage of query (82.8 bits)

LACC_LACLL / P23391 Tagatose-6-phosphate kinase; Phosphotagatokinase; EC 2.7.1.144 from Lactococcus lactis subsp. lactis (Streptococcus lactis) (see paper)
    29% identity, 86% coverage of query (82.8 bits)

2jgvB Structure of staphylococcus aureus d-tagatose-6-phosphate kinase in complex with adp
    28% identity, 86% coverage of query (82.8 bits)

2jg1C Structure of staphylococcus aureus d-tagatose-6-phosphate kinase with cofactor and substrate
    27% identity, 86% coverage of query (82.8 bits)

K1PF_HALVD / D4GYE6 1-phosphofructokinase; Fructose 1-phosphate kinase; Fru1PK; EC 2.7.1.56 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GYE6 1-phosphofructokinase (EC 2.7.1.56) from Haloferax volcanii (see paper)
    31% identity, 98% coverage of query (77.0 bits)

G4SW45 diphosphate-fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90) from Methylotuvimicrobium alcaliphilum (see paper)
    28% identity, 93% coverage of query (76.3 bits)

3ie7A / Q929S5 The crystal structure of phosphofructokinase (lin2199) from listeria innocua in complex with atp at 1.6a
    26% identity, 99% coverage of query (75.9 bits)

3julA Crystal structure of listeria innocua d-tagatose-6-phosphate kinase bound with substrate
    27% identity, 91% coverage of query (65.1 bits)

Q8VS15 D-tagatose-1-phosphate kinase (EC 2.7.1.234) from Klebsiella oxytoca (see paper)
    28% identity, 83% coverage of query (64.7 bits)

tagK / Q65EY9 D-tagatose-1-phosphate kinase (EC 2.7.1.234) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) (see 3 papers)
Q65EY9 D-tagatose-1-phosphate kinase (EC 2.7.1.234) from Bacillus licheniformis (see paper)
    25% identity, 99% coverage of query (62.4 bits)

6wb7A / Q8RMD4 Acarbose kinase acbk as a complex with acarbose and amp-pnp (see paper)
    29% identity, 84% coverage of query (47.4 bits)

ACBK_ACTS5 / Q8RMD4 Acarbose 7(IV)-phosphotransferase; Acarbose 7-kinase; EC 2.7.1.187 from Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110) (see paper)
Q8RMD4 acarbose 7IV-phosphotransferase (EC 2.7.1.187) from Actinoplanes sp. (see 2 papers)
acbK / CAD29481.2 acarbose 7-kinase AcbK from Actinoplanes sp. SE50/110 (see 5 papers)
    29% identity, 84% coverage of query (47.4 bits)

6wb7C Acarbose kinase acbk as a complex with acarbose and amp-pnp
    29% identity, 84% coverage of query (47.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory