Searching for up to 100 curated homologs for 3608577 FitnessBrowser__Dino:3608577 (325 a.a.)
Found high-coverage hits (≥70%) to 33 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TMBP_NOSS1 / Q8YSQ6 Monocarboxylate 2-oxoacid-binding periplasmic protein all3028; Extracellular solute-binding protein; Extracytoplasmic solute receptor protein all3028; TRAP transporter monocarboxylate 2-oxoacid-binding subunit P from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) (see paper)
TC 2.A.56.3.3 / Q8YSQ6 Extracellular solute-binding protein, component of The 2-oxo monocarboxylate transporter (Pernil et al., 2010). Transports pyruvate which is inhibited by various 2-ketoacids from Nostoc sp. (strain PCC 7120 / UTEX 2576) (see paper)
36% identity, 95% coverage of query (201 bits)
7ug8B / Q0I6F8 Crystal structure of a solute receptor from synechococcus cc9311 in complex with alpha-ketovaleric and calcium
34% identity, 99% coverage of query (192 bits)
2hzlB / Q3J1R2 Crystal structures of a sodium-alpha-keto acid binding subunit from a trap transporter in its closed forms (see paper)
34% identity, 92% coverage of query (190 bits)
TAKP_CERS4 / Q3J1R2 Alpha-keto acid-binding periplasmic protein TakP; Extracytoplasmic solute receptor protein TakP; TRAP transporter alpha-keto acid-binding subunit P; TRAP-T family sorbitol/mannitol transporter, periplasmic binding protein, SmoM from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter sphaeroides) (see paper)
34% identity, 92% coverage of query (190 bits)
4petA / Q48AL6 Crystal structure of a trap periplasmic solute binding protein from colwellia psychrerythraea (cps_0129, target efi-510097) with bound calcium and pyruvate (see paper)
34% identity, 94% coverage of query (190 bits)
TC 2.A.56.3.4 / D5ALT6 TRAP dicarboxylate transporter, DctP-2 subunit, component of The 2-ketomonocarboxylate transporter (presented in order of affinity - 2-oxovalerate [highest affinity, KD=0.1 μM], 2-oxoisovalerate, 2-oxobutyrate, 2-oxoisocaproate, 2-oxo-3-methylvalerate, pyruvate [lowest affinity, KD=3 μM]) from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
37% identity, 89% coverage of query (190 bits)
5cm6A Crystal structure of a trap periplasmic solute binding protein from pseudoalteromonas atlantica t6c(patl_2292, target efi-510180) with bound sodium and pyruvate
34% identity, 95% coverage of query (184 bits)
4yicA / A0A0J9X284 Crystal structure of a trap transporter solute binding protein (ipr025997) from bordetella bronchiseptica rb50 (bb0280, target efi- 500035) with bound picolinic acid
31% identity, 96% coverage of query (159 bits)
Build an alignment for 3608577 and 8 homologs with ≥ 30% identity
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2zzvA / Q5SK82 Crystal structure of a periplasmic substrate binding protein in complex with calcium and lactate (see paper)
28% identity, 88% coverage of query (107 bits)
TLBP_THET8 / Q5SK82 Lactate-binding periplasmic protein TTHA0766; ABC transporter, solute-binding protein; Extracytoplasmic solute receptor protein TTHA0766; TRAP transporter lactate-binding subunit P from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
28% identity, 88% coverage of query (107 bits)
2zzwA Crystal structure of a periplasmic substrate binding protein in complex with zinc and lactate
28% identity, 88% coverage of query (107 bits)
4pe3A / A3PQU4 Crystal structure of a trap periplasmic solute binding protein from rhodobacter sphaeroides (rsph17029_3620, target efi-510199), apo open structure (see paper)
25% identity, 88% coverage of query (81.3 bits)
TC 2.A.56.3.2 / Q9RBR1 FcbT1, component of Tripartite 4-chlorobenzoate symporter (also binds and may transport 4-bromo-, 4-iodo-, and 4-fluorobenzoate and with a lower affinity, 3-chlorobenzoate, 2-chlorobenzoate, 4-hydroxybenzoate, 3-hydroxybenzoate, and benzoate) (see paper)
23% identity, 81% coverage of query (68.6 bits)
PP_1169 D-glucuronate / D-galacturonate TRAP transporter, solute receptor component from Pseudomonas putida KT2440
23% identity, 83% coverage of query (54.3 bits)
4napD / Q315G1 Crystal structure of a trap periplasmic solute binding protein from desulfovibrio alaskensis g20 (dde_0634), target efi-510102, with bound d-tryptophan (see paper)
21% identity, 86% coverage of query (51.2 bits)
4pgpA Crystal structure of a trap periplasmic solute binding protein from desulfovibrio alaskensis g20 (dde_0634, target efi-510120) with bound 3-indole acetic acid
21% identity, 86% coverage of query (51.2 bits)
4pgnA Crystal structure of a trap periplasmic solute binding protein from desulfovibrio alaskensis g20 (dde_0634, target efi-510120) with bound indole pyruvate
21% identity, 86% coverage of query (51.2 bits)
DCTP2_OLEA2 / Q315G1 Solute-binding protein Dde_0634 from Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20) (Desulfovibrio alaskensis) (see paper)
21% identity, 86% coverage of query (50.8 bits)
4xfeA / I3UZ52 Crystal structure of a trap periplasmic solute binding protein from pseudomonas putida f1 (pput_1203), target efi-500184, with bound d- glucuronate
23% identity, 75% coverage of query (49.7 bits)
4ovrA / A7IKQ4 Crystal structure of a trap periplasmic solute binding protein from xanthobacter autotrophicus py2, target efi-510329, with bound beta-d- galacturonate (see paper)
25% identity, 77% coverage of query (49.7 bits)
TEAA_HALED / E1VBK1 Ectoine-binding periplasmic protein TeaA from Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9) (see 3 papers)
24% identity, 80% coverage of query (48.5 bits)
3gyyD / E1VBK1 The ectoine binding protein of the teaabc trap transporter teaa in the apo-state (see paper)
24% identity, 80% coverage of query (48.5 bits)
2vpnB High-resolution structure of the periplasmic ectoine- binding protein from teaabc trap-transporter of halomonas elongata
24% identity, 80% coverage of query (48.5 bits)
4magA Crystal structure of the periplasmic sialic acid binding protein from vibrio cholerea (see paper)
23% identity, 76% coverage of query (47.8 bits)
7a5qB Crystal structure of vcsiap bound to sialic acid
23% identity, 76% coverage of query (47.8 bits)
7a5qA Crystal structure of vcsiap bound to sialic acid
23% identity, 76% coverage of query (47.8 bits)
DCTP1_POLSJ / Q128M1 Solute-binding protein Bpro_3107 from Polaromonas sp. (strain JS666 / ATCC BAA-500) (see paper)
24% identity, 75% coverage of query (47.4 bits)
4mijA / Q128M1 Crystal structure of a trap periplasmic solute binding protein from polaromonas sp. Js666 (bpro_3107), target efi-510173, with bound alpha/beta d-galacturonate, space group p21 (see paper)
24% identity, 75% coverage of query (47.0 bits)
SIAP_VIBCH / Q9KR64 Sialic acid-binding periplasmic protein SiaP from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
TC 2.A.56.1.6 / Q9KR64 C4-dicarboxylate-binding periplasmic protein, component of The Na+-dependent sialic acid uptake porter, SiaPQM. SiaQ and SiaM form a 1:1 stoichiometric complex from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see paper)
23% identity, 76% coverage of query (47.0 bits)
4mhfA Crystal structure of a trap periplasmic solute binding protein from polaromonas sp. Js666 (bpro_3107), target efi-510173, with bound alpha/beta d-glucuronate, space group p21
24% identity, 75% coverage of query (47.0 bits)
2vpnA High-resolution structure of the periplasmic ectoine- binding protein from teaabc trap-transporter of halomonas elongata
24% identity, 80% coverage of query (45.4 bits)
2vpoA High resolution structure of the periplasmic binding protein teaa from teaabc trap transporter of halomonas elongata in complex with hydroxyectoine
24% identity, 80% coverage of query (45.1 bits)
4p8bA / Q0KC03 Crystal structure of a trap periplasmic solute binding protein from ralstonia eutropha h16 (h16_a1328), target efi-510189, with bound (s)-2-hydroxy-2-methyl-3-oxobutanoate ((s)-2-acetolactate) (see paper)
23% identity, 91% coverage of query (43.9 bits)
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Lawrence Berkeley National Laboratory