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Searching for up to 100 curated homologs for 3608582 Dshi_1976 PfkB domain protein (RefSeq) (305 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

H281DRAFT_01116 deoxyribose kinase (EC 2.7.1.15) from Paraburkholderia bryophila 376MFSha3.1
    60% identity, 99% coverage of query (314 bits)

BPHYT_RS25805 deoxyribose kinase (EC 2.7.1.15) from Burkholderia phytofirmans PsJN
    59% identity, 98% coverage of query (310 bits)

8cqxA / A0A0B0SD75 Ribokinase from t.Sp mutant a92g
    46% identity, 98% coverage of query (213 bits)

BWI76_RS00290 Ribokinase (EC 2.7.1.15) from Klebsiella michiganensis M5al
    43% identity, 99% coverage of query (190 bits)

BT2803 ribokinase (EC 2.7.1.15) from Bacteroides thetaiotaomicron VPI-5482
    39% identity, 97% coverage of query (190 bits)

A0A0H2UL04 ribokinase (EC 2.7.1.15) from Vibrio cholerae (see paper)
    41% identity, 100% coverage of query (183 bits)

4xckA / A0A0H2UL04 Vibrio cholerae o395 ribokinase complexed with adp, ribose and cesium ion. (see paper)
    41% identity, 100% coverage of query (183 bits)

RbsK / b3752 ribokinase (EC 2.7.1.15) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
rbsK / P0A9J6 ribokinase (EC 2.7.1.15) from Escherichia coli (strain K12) (see 19 papers)
RBSK_ECOLI / P0A9J6 Ribokinase; RK; EC 2.7.1.15 from Escherichia coli (strain K12) (see 5 papers)
rbsK / RF|NP_418208 ribokinase from Escherichia coli K12 (see 4 papers)
    42% identity, 98% coverage of query (181 bits)

1gqtB / P0A9J6 Activation of ribokinase by monovalent cations (see paper)
    42% identity, 98% coverage of query (181 bits)

1rk2A E. Coli ribokinase complexed with ribose and adp, solved in space group p212121
    42% identity, 98% coverage of query (181 bits)

deoK / Q8XGW5 deoxyribokinase monomer (EC 2.7.1.229) from Salmonella typhi (see 4 papers)
    35% identity, 99% coverage of query (180 bits)

RBSK_STAAC / A0A0H2WZY4 Ribokinase; RK; EC 2.7.1.15 from Staphylococcus aureus (strain COL) (see paper)
A0A0H2WZY4 ribokinase (EC 2.7.1.15) from Staphylococcus aureus (see paper)
    38% identity, 99% coverage of query (180 bits)

AO356_00950 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2C3
    41% identity, 99% coverage of query (172 bits)

RBSKI_FRUSL / P83534 Bifunctional ribokinase/ribose-5-phosphate isomerase A; EC 2.7.1.15; EC 5.3.1.6 from Fructilactobacillus sanfranciscensis (strain ATCC 27651 / DSM 20451 / JCM 5668 / CCUG 30143 / KCTC 3205 / NCIMB 702811 / NRRL B-3934 / L-12) (Lactobacillus sanfranciscensis) (see paper)
    38% identity, 98% coverage of query (170 bits)

6znxC / A0A0B0SD75 Ribokinase from thermus species
    43% identity, 91% coverage of query (167 bits)

AO353_20835 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2E3
    40% identity, 100% coverage of query (167 bits)

Pf1N1B4_6031 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N1B4
    41% identity, 100% coverage of query (166 bits)

BT2804 ribokinase (EC 2.7.1.15) from Bacteroides thetaiotaomicron VPI-5482
    35% identity, 99% coverage of query (157 bits)

RBSK_SCHPO / O60116 Ribokinase; RK; EC 2.7.1.15 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    35% identity, 97% coverage of query (153 bits)

6wjzA Crystal structure of human ribokinase in complex with ampcp
    36% identity, 97% coverage of query (152 bits)

2fv7A Crystal structure of human ribokinase
    37% identity, 97% coverage of query (152 bits)

5c41A / Q9H477 Crystal structure of human ribokinase in complex with amppcp in p21 spacegroup and with 4 protomers
    37% identity, 97% coverage of query (151 bits)

6wk0B Crystal structure of human ribokinase in complex with amppcp and ribose
    37% identity, 97% coverage of query (151 bits)

5c3yA Structure of human ribokinase crystallized with amppnp
    37% identity, 97% coverage of query (151 bits)

RBSK_HUMAN / Q9H477 Ribokinase; RK; EC 2.7.1.15 from Homo sapiens (Human) (see paper)
Q9H477 ribokinase (EC 2.7.1.15) from Homo sapiens (see paper)
    37% identity, 96% coverage of query (147 bits)

5byfA Crystal structure of human ribokinase in complex with amp
    37% identity, 96% coverage of query (147 bits)

SMc01103 Ribokinase (EC 2.7.1.15) from Sinorhizobium meliloti 1021
    37% identity, 98% coverage of query (140 bits)

6ilsB / A1A6H3 Structure of arabidopsis thaliana ribokinase complexed with ribose and atp (see paper)
    35% identity, 100% coverage of query (139 bits)

RBSK / A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see 2 papers)
RBSK_ARATH / A1A6H3 Ribokinase; AtRBSK; RK; EC 2.7.1.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see paper)
    35% identity, 99% coverage of query (138 bits)

HSERO_RS11500 Ribokinase (EC 2.7.1.15) from Herbaspirillum seropedicae SmR1
    38% identity, 97% coverage of query (137 bits)

RBSK_LEIMA / E9AD19 Ribokinase; RK; EC 2.7.1.15 from Leishmania major (see paper)
    32% identity, 98% coverage of query (130 bits)

6a8aA / A0A3S7X0F5 Ribokinase from leishmania donovani with atp (see paper)
    32% identity, 98% coverage of query (125 bits)

6a8cA Ribokinase from leishmania donovani with adp
    32% identity, 98% coverage of query (125 bits)

6a8bA Ribokinase from leishmania donovani with amppcp
    32% identity, 98% coverage of query (125 bits)

Q8NQR0 ribokinase (EC 2.7.1.15) from Corynebacterium glutamicum (see paper)
    34% identity, 97% coverage of query (124 bits)

Q42896 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    31% identity, 89% coverage of query (98.2 bits)

Build an alignment

Build an alignment for 3608582 and 36 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

RBSK_YEAST / P25332 Ribokinase; RK; EC 2.7.1.15 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    28% identity, 97% coverage of query (97.4 bits)

P37829 fructokinase (EC 2.7.1.4) from Solanum tuberosum (see 2 papers)
    31% identity, 89% coverage of query (95.5 bits)

Q9SID0 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    30% identity, 89% coverage of query (94.0 bits)

SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
    32% identity, 89% coverage of query (94.0 bits)

SCRK1_ORYSJ / Q0JGZ6 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
    32% identity, 89% coverage of query (94.0 bits)

SCRK1_MAIZE / Q6XZ79 Fructokinase-1; ZmFRK1; EC 2.7.1.4 from Zea mays (Maize)
    32% identity, 89% coverage of query (91.7 bits)

Q9LNE4 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    30% identity, 87% coverage of query (89.4 bits)

Q9M1B9 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    29% identity, 89% coverage of query (88.6 bits)

Q42645 fructokinase (EC 2.7.1.4) from Beta vulgaris (see paper)
    29% identity, 87% coverage of query (87.8 bits)

3ikhA / A6T989 Crystal structure of ribokinase in complex with atp and glycerol in the active site from klebsiella pneumoniae
    27% identity, 98% coverage of query (82.0 bits)

3i3yD Crystal structure of ribokinase in complex with d-ribose from klebsiella pneumoniae
    27% identity, 98% coverage of query (82.0 bits)

Q9YG89 6-phosphofructokinase (EC 2.7.1.11) from Aeropyrum pernix (see 2 papers)
    27% identity, 97% coverage of query (80.5 bits)

P71913 ribokinase (EC 2.7.1.15) from Mycobacterium tuberculosis (see paper)
    33% identity, 95% coverage of query (77.8 bits)

3in1A / P77493 Crystal structure of a putative ribokinase in complex with adp from e.Coli
    25% identity, 90% coverage of query (77.8 bits)

YdjH / b1772 L-glycero-L-galacto-octuluronate kinase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
ydjH / P77493 L-glycero-L-galacto-octuluronate kinase from Escherichia coli (strain K12) (see 2 papers)
    25% identity, 90% coverage of query (77.8 bits)

7aghA Crystal structure of sf kinase yihv from e. Coli in complex with amppnp-mg
    32% identity, 99% coverage of query (77.8 bits)

3go6A / P71913 Crystal structure of m. Tuberculosis ribokinase (rv2436) in complex with ribose and amp-pnp
    33% identity, 94% coverage of query (77.4 bits)

7ag6A / P32143 Crystal structure of sf kinase yihv from e. Coli in complex with sulfofructose (sf), adp-mg (see paper)
    31% identity, 99% coverage of query (77.4 bits)

O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    28% identity, 89% coverage of query (77.4 bits)

3go6B Crystal structure of m. Tuberculosis ribokinase (rv2436) in complex with ribose and amp-pnp
    33% identity, 94% coverage of query (77.4 bits)

SquV / b3883 6-deoxy-6-sulfofructose kinase (EC 2.7.1.184) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yihV / P32143 6-deoxy-6-sulfofructose kinase (EC 2.7.1.184) from Escherichia coli (strain K12) (see 2 papers)
SQUV_ECOLI / P32143 Sulfofructose kinase; SF kinase; EC 2.7.1.184 from Escherichia coli (strain K12) (see 2 papers)
    31% identity, 99% coverage of query (77.0 bits)

Q9FLH8 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    28% identity, 89% coverage of query (77.0 bits)

7agkA Crystal structure of e. Coli sf kinase (yihv) in complex with product sulfofructose phosphate (sfp)
    31% identity, 99% coverage of query (77.0 bits)

SCRK2_ORYSI / A2YQL4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
SCRK2_ORYSJ / Q0J8G4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
A2YQL4 fructokinase (EC 2.7.1.4) from Oryza sativa (see paper)
    28% identity, 89% coverage of query (76.3 bits)

Dshi_2797 Fructokinase (EC 2.7.1.4) from Dinoroseobacter shibae DFL-12
    31% identity, 88% coverage of query (76.3 bits)

Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    29% identity, 89% coverage of query (72.4 bits)

Q0K080 dehydrogluconokinase (EC 2.7.1.13); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus necator (see paper)
    29% identity, 89% coverage of query (70.1 bits)

6xk2A / J9VQ51 Crystal structure of ribokinase from cryptococcus neoformans var. Grubii serotype a in complex with adp
    28% identity, 93% coverage of query (69.7 bits)

O82616 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    27% identity, 89% coverage of query (68.9 bits)

kdgK / Q97U29 2-dehydro-3-deoxyglucono/2-dehydro-3-deoxygalactonokinase monomer (EC 2.7.1.178) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see 3 papers)
KDGK_SACS2 / Q97U29 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxy-galactonokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; KDGal kinase; EC 2.7.1.178 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
Q97U29 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178) from Saccharolobus solfataricus (see 5 papers)
    22% identity, 90% coverage of query (67.8 bits)

PGA1_c07240 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92) from Phaeobacter inhibens BS107
    27% identity, 88% coverage of query (67.8 bits)

2varA / Q97U29 Crystal structure of sulfolobus solfataricus 2-keto-3-deoxygluconate kinase complexed with 2-keto-3-deoxygluconate (see paper)
    22% identity, 90% coverage of query (67.4 bits)

N515DRAFT_1919 Fructokinase (EC 2.7.1.4) from Dyella japonica UNC79MFTsu3.2
    30% identity, 89% coverage of query (65.9 bits)

3iq0B / A0A0H2VDX9 Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
    27% identity, 81% coverage of query (64.7 bits)

PfkB / b1723 6-phosphofructokinase 2 (EC 2.7.1.11; EC 2.7.1.144) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
pfkB / P06999 6-phosphofructokinase 2 (EC 2.7.1.11; EC 2.7.1.144) from Escherichia coli (strain K12) (see 40 papers)
PFKB_ECOLI / P06999 ATP-dependent 6-phosphofructokinase isozyme 2; ATP-PFK 2; Phosphofructokinase 2; 6-phosphofructokinase isozyme II; Phosphohexokinase 2; EC 2.7.1.11 from Escherichia coli (strain K12) (see 4 papers)
P06999 6-phosphofructokinase (EC 2.7.1.11) from Escherichia coli (see 2 papers)
3n1cA / P06999 Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with fructose-6-phosphate (see paper)
    29% identity, 83% coverage of query (64.7 bits)

3uqdB Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with substrates and products
    29% identity, 83% coverage of query (64.7 bits)

3uqdA Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with substrates and products
    29% identity, 83% coverage of query (64.7 bits)

3uqeA Crystal structure of the phosphofructokinase-2 mutant y23d from escherichia coli
    31% identity, 81% coverage of query (64.7 bits)

STM4066 / Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
AIRSK_SALTY / Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
    27% identity, 90% coverage of query (64.3 bits)

SCRK2_MAIZE / Q6XZ78 Fructokinase-2; ZmFRK2; EC 2.7.1.4 from Zea mays (Maize)
    28% identity, 89% coverage of query (64.3 bits)

3cqdA Structure of the tetrameric inhibited form of phosphofructokinase-2 from escherichia coli
    30% identity, 81% coverage of query (64.3 bits)

yeiC / Q1R9Q6 pseudouridine kinase (EC 2.7.1.83) from Escherichia coli (strain UTI89 / UPEC) (see 2 papers)
    25% identity, 91% coverage of query (63.5 bits)

cscK / GB|CAA57218.2 fructokinase; EC 2.7.1.4 from Escherichia coli (see paper)
    26% identity, 87% coverage of query (63.2 bits)

RR42_RS28860 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus basilensis FW507-4G11
    30% identity, 88% coverage of query (62.4 bits)

7w93A / A0A140N873 Crystal structure of e.Coli pseudouridine kinase psuk complexed with n1-methyl-pseudouridine (see paper)
    27% identity, 81% coverage of query (62.4 bits)

1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog
    28% identity, 90% coverage of query (62.4 bits)

1tz3A / Q8ZKR2 Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
    28% identity, 90% coverage of query (62.4 bits)

7vtfA Cytidine bound structure of pseudouridine kinase (puki) from escherichia coli strain b
    26% identity, 81% coverage of query (61.6 bits)

7vteA Uridine bound structure of pseudouridine kinase (puki) from escherichia coli strain b
    26% identity, 81% coverage of query (61.6 bits)

PsuK / b2166 putative pseudouridine kinase (EC 2.7.1.83) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PSUK_ECOLI / P30235 Pseudouridine kinase; EC 2.7.1.83 from Escherichia coli (strain K12) (see paper)
P30235 pseudouridine kinase (EC 2.7.1.83) from Escherichia coli (see paper)
    26% identity, 81% coverage of query (61.2 bits)

KDGK_SULTO / Q96XN9 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxy-D-gluconate kinase; KDG kinase; KDGK; EC 2.7.1.45 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
Q96XN9 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Sulfurisphaera tokodaii (see paper)
    22% identity, 89% coverage of query (59.7 bits)

2dcnA / Q96XN9 Crystal structure of 2-keto-3-deoxygluconate kinase from sulfolobus tokodaii complexed with 2-keto-6-phosphogluconate (alpha-furanose form)
    22% identity, 89% coverage of query (59.7 bits)

3b1rA Structure of burkholderia thailandensis nucleoside kinase (bthnk) in complex with amp-mg-amp
    29% identity, 87% coverage of query (58.9 bits)

3b1pA Structure of burkholderia thailandensis nucleoside kinase (bthnk) in complex with adp-inosine
    29% identity, 87% coverage of query (58.9 bits)

3b1nB / Q2SZE4 Structure of burkholderia thailandensis nucleoside kinase (bthnk) in complex with adp-mizoribine (see paper)
    29% identity, 87% coverage of query (58.9 bits)

5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
    25% identity, 88% coverage of query (55.1 bits)

5yggA / A0A0H3AER7 Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
    25% identity, 88% coverage of query (53.1 bits)

8omdA / P97328 Crystal structure of mkhk in complex with compound-4 (see paper)
    24% identity, 91% coverage of query (51.2 bits)

6p2dA Structure of mouse ketohexokinasE-C in complex with fructose and adp
    24% identity, 91% coverage of query (51.2 bits)

4lc4A Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with guanosine
    25% identity, 86% coverage of query (49.7 bits)

4kbeA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with benzoguanamine
    25% identity, 86% coverage of query (49.7 bits)

4kanA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 2-(2,5-dimethyl-1,3-thiazol-4-yl)acetic acid
    25% identity, 86% coverage of query (49.7 bits)

4kalA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with quinoline-3-carboxylic acid
    25% identity, 86% coverage of query (49.7 bits)

4kahA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 4-bromo-1h-pyrazole
    25% identity, 86% coverage of query (49.7 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory