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Searching for up to 100 curated homologs for 3608636 FitnessBrowser__Dino:3608636 (352 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

RbsR / VIMSS3585769 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Thermotoga petrophila RKU-1
    34% identity, 93% coverage of query (184 bits)

IolR2 / VIMSS853979 IolR2 regulator of Inositol utilization (repressor) from Geobacillus kaustophilus HTA426
    33% identity, 93% coverage of query (179 bits)

RbsR / VIMSS2089734 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Acidovorax avenae subsp. citrulli AAC00-1
    35% identity, 94% coverage of query (174 bits)

ManR2 / VIMSS6936097 ManR2 regulator of Mannose utilization; Mannosides utilization, effector Mannose (repressor) from Shewanella amazonensis SB2B
    33% identity, 94% coverage of query (172 bits)

DegA / VIMSS727211 DegA regulator of Inositol utilization (repressor) from Bacillus licheniformis DSM 13
    35% identity, 86% coverage of query (170 bits)

RbsR / VIMSS3647698 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Petrotoga mobilis SJ95
    32% identity, 93% coverage of query (167 bits)

IolR2 / VIMSS64894 IolR2 regulator of Inositol utilization (repressor) from Bacillus halodurans C-125
    32% identity, 93% coverage of query (167 bits)

1jftA / P0ACP7 Purine repressor mutant-hypoxanthine-purf operator complex (see paper)
    32% identity, 94% coverage of query (167 bits)

2puaA Crystal structure of the laci family member, purr, bound to dna: minor groove binding by alpha helices
    32% identity, 94% coverage of query (166 bits)

2pubA Crystal structure of the laci family member, purr, bound to dna: minor groove binding by alpha helices
    32% identity, 94% coverage of query (166 bits)

PurR / b1658 DNA-binding transcriptional repressor PurR from Escherichia coli K-12 substr. MG1655 (see 7 papers)
PurR / P0ACP7 DNA-binding transcriptional repressor PurR from Escherichia coli (strain K12) (see 3 papers)
PURR_ECOLI / P0ACP7 HTH-type transcriptional repressor PurR; Pur regulon repressor; Purine nucleotide synthesis repressor from Escherichia coli (strain K12) (see 8 papers)
PurR / P0ACP7 Transcription factor PurR (repressor) from Escherichia coli K12 MG1655 (see 5 papers)
    32% identity, 94% coverage of query (165 bits)

1wetA Structure of the purr-guanine-purf operator complex
    32% identity, 94% coverage of query (165 bits)

PurR / VIMSS3403341 PurR regulator of Purine metabolism, effector Hypoxanthine; Guanine (repressor) from Citrobacter koseri ATCC BAA-895
    33% identity, 86% coverage of query (164 bits)

DegA / VIMSS37616 DegA regulator of Inositol utilization (repressor) from Bacillus subtilis subsp. subtilis str. 168
    31% identity, 94% coverage of query (163 bits)

GalR / VIMSS7272257 GalR regulator of Galactosides utilization, effector Galactose (repressor) from Thermotoga sp. RQ2
    32% identity, 86% coverage of query (163 bits)

RbsR / VIMSS3487054 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Actinobacillus succinogenes 130Z
    32% identity, 93% coverage of query (162 bits)

RbsR / VIMSS776892 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Photobacterium profundum SS9
    33% identity, 86% coverage of query (162 bits)

Build an alignment

Build an alignment for 3608636 and 17 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

CcpA / VIMSS5975895 CcpA regulator of Carbohydrate metabolism, effector HPr, phosphocarrier protein (activator/repressor) from Clostridium butyricum 5521
    29% identity, 93% coverage of query (161 bits)

PurR / VIMSS5790377 PurR regulator of Purine metabolism, effector Hypoxanthine; Guanine (repressor) from Actinobacillus pleuropneumoniae serovar 7 str. AP76
    32% identity, 86% coverage of query (161 bits)

RbsR / VIMSS3565790 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Aeromonas salmonicida subsp. salmonicida A449
    31% identity, 86% coverage of query (159 bits)

RbsR / VIMSS547489 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Photorhabdus luminescens TTO1
    31% identity, 93% coverage of query (159 bits)

DegA / VIMSS6923706 DegA regulator of Inositol utilization (repressor) from Paenibacillus sp. JDR-2
    31% identity, 88% coverage of query (159 bits)

RbsR / VIMSS218141 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Pseudomonas putida KT2440
    34% identity, 86% coverage of query (158 bits)

CytR / b3934 DNA-binding transcriptional repressor CytR from Escherichia coli K-12 substr. MG1655 (see 8 papers)
CytR / P0ACN7 Transcription factor CytR (repressor) from Escherichia coli K12 MG1655 (see 7 papers)
cytR / GB|AAN45445.2 HTH-type transcriptional repressor cytR from Shigella flexneri (see 5 papers)
    31% identity, 90% coverage of query (158 bits)

RbsR / VIMSS8507552 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Desulfovibrio salexigens DSM 2638
    32% identity, 87% coverage of query (157 bits)

RbsR / VIMSS10257457 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Edwardsiella tarda EIB202
    32% identity, 93% coverage of query (157 bits)

CcpA / VIMSS279005 CcpA regulator of Carbon catabolism, effector HPr, phosphocarrier protein from Oceanobacillus iheyensis HTE831
    30% identity, 87% coverage of query (156 bits)

RbsR / VIMSS3677555 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Thermotoga lettingae TMO
    29% identity, 95% coverage of query (155 bits)

RbsR / VIMSS5475947 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Thermotoga neapolitana DSM 4359
    31% identity, 93% coverage of query (155 bits)

PurR / VIMSS3482290 PurR regulator of Purine metabolism, effector Hypoxanthine; Guanine (repressor) from Vibrio harveyi ATCC BAA-1116
    31% identity, 86% coverage of query (155 bits)

CcpA / P46828 Transcription factor CcpA (repressor) from Bacillus megaterium (see 3 papers)
1rzrG / P46828 Crystal structure of transcriptional regulator- phosphoprotein-DNA complex (see paper)
ccpA / AAA22295.1 catabolite control protein from Bacillus megaterium (see paper)
    30% identity, 87% coverage of query (154 bits)

GntR / VIMSS10479324 GntR regulator of Gluconate utilization, effector Gluconate (repressor) from Erwinia amylovora ATCC 49946
    32% identity, 87% coverage of query (154 bits)

PurR / VIMSS5493862 PurR regulator of Purine metabolism, effector Hypoxanthine; Guanine (repressor) from Vibrio salmonicida LFI1238
    30% identity, 86% coverage of query (154 bits)

RbsR / VIMSS1972790 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Psychromonas ingrahamii 37
    32% identity, 94% coverage of query (154 bits)

RbsR / VIMSS6797332 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Haemophilus somnus 2336
    31% identity, 93% coverage of query (154 bits)

1rzrA Crystal structure of transcriptional regulator- phosphoprotein-DNA complex
    30% identity, 87% coverage of query (154 bits)

DegA / VIMSS853765 DegA regulator of Inositol utilization (repressor) from Geobacillus kaustophilus HTA426
    32% identity, 86% coverage of query (153 bits)

RbsR / VIMSS5693478 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Thermosipho africanus TCF52B
    31% identity, 93% coverage of query (153 bits)

GntR / b3438 DNA-binding transcriptional repressor GntR from Escherichia coli K-12 substr. MG1655 (see 14 papers)
GntR / P0ACP5 Transcription factor GntR (repressor) from Escherichia coli K12 MG1655 (see 2 papers)
    32% identity, 87% coverage of query (153 bits)

BglR / VIMSS6932414 BglR regulator of Beta-glucosides utilization, effector Beta-glucoside (repressor) from Shewanella baltica OS155
    32% identity, 85% coverage of query (153 bits)

3oqoA / P25144 Ccpa-hpr-ser46p-syn cre (see paper)
    28% identity, 87% coverage of query (152 bits)

GNTR_PSEAE / Q9I1F6 HTH-type transcriptional regulator GntR from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    32% identity, 92% coverage of query (152 bits)

CCPA_BACSU / P25144 Catabolite control protein A; Glucose-resistance amylase regulator from Bacillus subtilis (strain 168) (see 7 papers)
CcpA / P25144 Transcription factor CcpA (activator/repressor) from Bacillus subtilis 168 (see 12 papers)
CcpA / VIMSS39510 CcpA regulator of Carbon catabolism, effector HPr, phosphocarrier protein from Bacillus subtilis subsp. subtilis str. 168
    28% identity, 87% coverage of query (152 bits)

PurR / VIMSS760563 PurR regulator of Purine metabolism, effector Hypoxanthine; Guanine (repressor) from Mannheimia succiniciproducens MBEL55E
    30% identity, 86% coverage of query (152 bits)

RbsR / b3753 DNA-binding transcriptional dual regulator RbsR from Escherichia coli K-12 substr. MG1655 (see 7 papers)
rbsR ribose operon repressor from Escherichia coli K12 (see 5 papers)
    34% identity, 86% coverage of query (152 bits)

GntR / VIMSS3627014 GntR regulator of Gluconate utilization, effector Gluconate (repressor) from Enterobacter sp. 638
    31% identity, 87% coverage of query (152 bits)

BglR / VIMSS6937230 BglR regulator of Beta-glucosides utilization, effector Beta-glucoside (repressor) from Shewanella amazonensis SB2B
    33% identity, 85% coverage of query (151 bits)

CcpA / A0A125V3V0_CLODI Transcription factor CcpA (activator/repressor) from Clostridioides difficile 630 (see paper)
CcpA / VIMSS3373464 CcpA regulator of Carbon catabolism; Carbohydrate metabolism, effector HPr, phosphocarrier protein (activator/repressor) from Clostridium difficile 630
    31% identity, 87% coverage of query (151 bits)

CcpA / VIMSS824262 CcpA regulator of Carbon catabolism, effector HPr, phosphocarrier protein from Bacillus clausii KSM-K16
    29% identity, 88% coverage of query (151 bits)

GloR / VIMSS3676221 GloR regulator of Fucose-glucose oligosaccharide utilization (repressor) from Thermotoga lettingae TMO
    28% identity, 94% coverage of query (150 bits)

CelR / VIMSS3585527 CelR regulator of Cellobiose utilization, effector Cellobiose (repressor) from Thermotoga petrophila RKU-1
    30% identity, 93% coverage of query (149 bits)

RbsR / VIMSS3485850 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Vibrio harveyi ATCC BAA-1116
    29% identity, 94% coverage of query (149 bits)

GntR / VIMSS6935472 GntR regulator of Gluconate utilization, effector Gluconate (repressor) from Shewanella baltica OS155
    30% identity, 88% coverage of query (149 bits)

RbsR / VIMSS6853 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Haemophilus influenzae Rd KW20
    31% identity, 86% coverage of query (149 bits)

RbsR / VIMSS2058498 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Lactobacillus brevis ATCC 367
    31% identity, 94% coverage of query (148 bits)

CcpA / VIMSS6925557 CcpA regulator of Carbon catabolism, effector HPr, phosphocarrier protein from Paenibacillus sp. JDR-2
    30% identity, 93% coverage of query (148 bits)

RbsR / VIMSS7512041 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Thermotogales bacterium TBF 19.5.1
    31% identity, 93% coverage of query (147 bits)

NtdR / VIMSS3425151 NtdR regulator of Neotrehalosadiamine biosynthesis, effector 3,3'-neotrehalosadiamine (activator) from Bacillus pumilus SAFR-032
    29% identity, 93% coverage of query (147 bits)

GalR / VIMSS5694380 GalR regulator of Galactosides utilization, effector Galactose (repressor) from Thermosipho africanus TCF52B
    28% identity, 93% coverage of query (147 bits)

RbsR / VIMSS5701545 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Anoxybacillus flavithermus WK1
    31% identity, 93% coverage of query (146 bits)

CcpA / VIMSS2056397 CcpA regulator of Carbohydrate metabolism, effector HPr, phosphocarrier protein (activator/repressor) from Clostridium novyi NT
    29% identity, 93% coverage of query (145 bits)

RbsR / VIMSS7180207 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Ralstonia pickettii 12J
    30% identity, 88% coverage of query (145 bits)

RbsR / VIMSS5824580 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Haemophilus parasuis SH0165
    31% identity, 82% coverage of query (144 bits)

RbsR / VIMSS5503837 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Lactobacillus fermentum IFO 3956
    31% identity, 94% coverage of query (144 bits)

RbsR / VIMSS5236429 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Vibrio splendidus LGP32
    28% identity, 94% coverage of query (144 bits)

RbsR / VIMSS3401761 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Citrobacter koseri ATCC BAA-895
    32% identity, 86% coverage of query (143 bits)

RbsR / VIMSS1059131 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Burkholderia sp. 383
    32% identity, 89% coverage of query (143 bits)

GalR / VIMSS3562401 GalR regulator of Galactosides utilization, effector Galactose (repressor) from Fervidobacterium nodosum Rt17-B1
    28% identity, 93% coverage of query (142 bits)

ccpA / CAA64713.1 ccpA from Staphylococcus xylosus (see paper)
    30% identity, 87% coverage of query (142 bits)

IdnR / VIMSS3621298 IdnR regulator of Idonate utilization, effector L-idonate; 5-dehydro-D-gluconate (activator/repressor) from Serratia proteamaculans 568
    33% identity, 93% coverage of query (142 bits)

GalR / VIMSS3647608 GalR regulator of Galactosides utilization, effector Galactose (repressor) from Petrotoga mobilis SJ95
    28% identity, 89% coverage of query (141 bits)

AscG / VIMSS3405739 AscG regulator of Beta-glucosides utilization; Cellobiose utilization, effector Cellobiose-6-phosphate; Beta-glucoside-6-phosphate (repressor) from Citrobacter koseri ATCC BAA-895
    31% identity, 94% coverage of query (141 bits)

NtdR / VIMSS729913 NtdR regulator of Neotrehalosadiamine biosynthesis, effector 3,3'-neotrehalosadiamine (activator) from Bacillus licheniformis DSM 13
    28% identity, 88% coverage of query (140 bits)

CcpA / VIMSS1789095 CcpA regulator of Global catabolite repression, effector Fructose-1,6-bisphosphate; HPr, phosphocarrier protein from Lactococcus lactis cremoris SK11
    29% identity, 93% coverage of query (140 bits)

RbsR / VIMSS58399 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Pseudomonas aeruginosa PAO1
    31% identity, 86% coverage of query (140 bits)

CcpA / VIMSS1099376 CcpA regulator of Carbon catabolism, effector HPr, phosphocarrier protein; Fructose-1,6-bisphosphate from Lactobacillus sakei subsp. sakei 23K
    30% identity, 93% coverage of query (139 bits)

ExuR / VIMSS3427925 ExuR regulator of Glucuronate utilization; Galacturonate utilization, effector Glucuronate; Galacturonate (repressor) from Bacillus pumilus SAFR-032
    26% identity, 94% coverage of query (139 bits)

reg1 / CAA66898.1 regulatory protein from Streptomyces lividans (see paper)
    34% identity, 92% coverage of query (138 bits)

AscG / b2714 DNA-binding transcriptional repressor AscG from Escherichia coli K-12 substr. MG1655 (see 4 papers)
    30% identity, 93% coverage of query (138 bits)

DegA / VIMSS64800 DegA regulator of Inositol utilization (repressor) from Bacillus halodurans C-125
    29% identity, 86% coverage of query (137 bits)

GloR / VIMSS7271239 GloR regulator of Fucose-glucose oligosaccharide utilization (repressor) from Thermotoga sp. RQ2
    28% identity, 93% coverage of query (137 bits)

EXUR_BACSU / Q9JMQ1 Probable HTH-type transcriptional repressor ExuR; Probable galacturonate locus repressor from Bacillus subtilis (strain 168) (see paper)
    29% identity, 93% coverage of query (137 bits)

GntR / VIMSS5784772 GntR regulator of Gluconate utilization, effector Gluconate (repressor) from Proteus mirabilis HI4320
    28% identity, 88% coverage of query (137 bits)

ExuR / VIMSS1099082 ExuR regulator of Glucuronate utilization; Galacturonate utilization, effector Galacturonate; Glucuronate (repressor) from Lactobacillus sakei subsp. sakei 23K
    30% identity, 86% coverage of query (137 bits)

2jcgA Apo form of the catabolite control protein a (ccpa) from bacillus megaterium, with the DNA binding domain
    28% identity, 87% coverage of query (137 bits)

RbsR / VIMSS2859848 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Psychromonas sp. CNPT3
    30% identity, 93% coverage of query (136 bits)

IdnR / VIMSS3404460 IdnR regulator of Idonate utilization, effector L-idonate; 5-dehydro-D-gluconate (activator/repressor) from Citrobacter koseri ATCC BAA-895
    30% identity, 88% coverage of query (136 bits)

CcpA / VIMSS3672556 CcpA regulator of Carbohydrate metabolism, effector HPr, phosphocarrier protein (activator/repressor) from Clostridium botulinum A str. ATCC 3502
    26% identity, 93% coverage of query (135 bits)

CelR / VIMSS3563589 CelR regulator of Cellobiose utilization, effector Cellobiose (repressor) from Fervidobacterium nodosum Rt17-B1
    30% identity, 94% coverage of query (135 bits)

CcpA / VIMSS530762 CcpA regulator of Carbon catabolism, effector HPr, phosphocarrier protein; Fructose-1,6-bisphosphate from Lactobacillus johnsonii NCC 533
    31% identity, 87% coverage of query (134 bits)

NTDR_BACSU / O07567 NTD biosynthesis operon regulator NtdR from Bacillus subtilis (strain 168) (see paper)
NtdR / VIMSS37589 NtdR regulator of Neotrehalosadiamine biosynthesis, effector 3,3'-neotrehalosadiamine (activator) from Bacillus subtilis subsp. subtilis str. 168
    27% identity, 88% coverage of query (134 bits)

RbsR / VIMSS2181734 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Oenococcus oeni PSU-1
    28% identity, 87% coverage of query (134 bits)

CcpA / VIMSS2180080 CcpA regulator of Carbon catabolism, effector HPr, phosphocarrier protein; Fructose-1,6-bisphosphate from Leuconostoc mesenteroides mesent. 8293
    29% identity, 88% coverage of query (134 bits)

ExuR / VIMSS729492 ExuR regulator of Glucuronate utilization; Galacturonate utilization, effector Glucuronate; Galacturonate (repressor) from Bacillus licheniformis DSM 13
    28% identity, 93% coverage of query (134 bits)

CcpA / VIMSS6431941 CcpA regulator of Carbon catabolism, effector HPr, phosphocarrier protein; Fructose-1,6-diphosphate (activator/repressor) from Staphylococcus capitis SK14
    29% identity, 87% coverage of query (134 bits)

RbsR / VIMSS2180326 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Leuconostoc mesenteroides mesent. 8293
    30% identity, 95% coverage of query (134 bits)

CcpA / VIMSS331101 CcpA regulator of Carbon catabolism, effector HPr, phosphocarrier protein; Fructose-1,6-bisphosphate from Lactobacillus plantarum WCFS1
    28% identity, 87% coverage of query (134 bits)

ExuR / VIMSS3455617 ExuR regulator of Glucuronate utilization; Galacturonate utilization, effector Glucuronate; Galacturonate (repressor) from Bacillus amyloliquefaciens FZB42
    27% identity, 94% coverage of query (133 bits)

AscG / VIMSS3618543 AscG regulator of Beta-glucosides utilization; Cellobiose utilization, effector Cellobiose-6-phosphate; Beta-glucoside-6-phosphate (repressor) from Serratia proteamaculans 568
    32% identity, 88% coverage of query (133 bits)

GalR / b2837 DNA-binding transcriptional dual regulator GalR from Escherichia coli K-12 substr. MG1655 (see 15 papers)
GalR / P03024 Transcription factor GalR (repressor) from Escherichia coli K12 MG1655 (see paper)
galR / GB|AAC75876.1 HTH-type transcriptional regulator galR from Escherichia coli K12 (see 6 papers)
    33% identity, 82% coverage of query (133 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory