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Searching for up to 100 curated homologs for 3608752 FitnessBrowser__Dino:3608752 (344 a.a.)

Found high-coverage hits (≥70%) to 24 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ltaA / O07051 L-allo-threonine aldolase subunit (EC 4.1.2.48) from Aeromonas jandaei (see paper)
LTAA_AERJA / O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see 2 papers)
O07051 L-allo-threonine aldolase (EC 4.1.2.49) from Aeromonas jandaei (see 4 papers)
ltaA / GB|BAA20404.1 L-allo-threonine aldolase; EC 4.1.2.- from Aeromonas jandaei (see 2 papers)
    49% identity, 96% coverage of query (298 bits)

3wgcB / O07051 Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
    49% identity, 96% coverage of query (296 bits)

3wgbD Crystal structure of aeromonas jandaei l-allo-threonine aldolase
    49% identity, 96% coverage of query (284 bits)

LtaA / b0870 low-specificity L-threonine aldolase (EC 4.1.2.48; EC 4.1.2.5; EC 4.1.2.26; EC 4.1.2.49) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ltaE / P75823 low-specificity L-threonine aldolase (EC 4.1.2.48; EC 4.1.2.26) from Escherichia coli (strain K12) (see 4 papers)
LTAE_ECOLI / P75823 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Escherichia coli (strain K12) (see paper)
P75823 low-specificity L-threonine aldolase (EC 4.1.2.48) from Escherichia coli (see 2 papers)
itaE / GB|BAA20882.1 threonine aldolase; EC 4.1.2.5 from Escherichia coli K12 (see 4 papers)
    46% identity, 96% coverage of query (280 bits)

3wlxA Crystal structure of low-specificity l-threonine aldolase from escherichia coli
    46% identity, 96% coverage of query (280 bits)

4lnjA Structure of escherichia coli threonine aldolase in unliganded form (see paper)
    46% identity, 96% coverage of query (278 bits)

4lnmA Structure of escherichia coli threonine aldolase in complex with serine
    46% identity, 96% coverage of query (278 bits)

4rjyA Crystal structure of e. Coli l-threonine aldolase in complex with a non-covalently uncleaved bound l-serine substrate
    46% identity, 96% coverage of query (278 bits)

4lnlA Structure of escherichia coli threonine aldolase in complex with allo- thr
    46% identity, 96% coverage of query (278 bits)

1jg8D / Q9X266 Crystal structure of threonine aldolase (low-specificity)
    44% identity, 96% coverage of query (267 bits)

Q9X266 L-threonine aldolase (EC 4.1.2.5) from Thermotoga maritima (see paper)
    44% identity, 96% coverage of query (267 bits)

1lw5B X-ray structure of l-threonine aldolase (low-specificity) in complex with glycine
    44% identity, 96% coverage of query (267 bits)

1lw4B X-ray structure of l-threonine aldolase (low-specificity) in complex with l-allo-threonine
    44% identity, 96% coverage of query (267 bits)

THA2_ARATH / Q9FPH3 Probable low-specificity L-threonine aldolase 2; Threonine aldolase 2; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    41% identity, 96% coverage of query (243 bits)

THA1_ARATH / Q8RXU4 Low-specificity L-threonine aldolase 1; Threonine aldolase 1; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    40% identity, 96% coverage of query (236 bits)

GLY1 / GB|AAA72430.1 threonine aldolase; EC 4.1.2.5 from Saccharomyces cerevisiae (see paper)
    35% identity, 95% coverage of query (164 bits)

GLY1 / P37303 L-threonine aldolase subunit (EC 4.1.2.48) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
GLY1_YEAST / P37303 Low specificity L-threonine aldolase; Low specificity L-TA; TA; EC 4.1.2.48 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P37303 low-specificity L-threonine aldolase (EC 4.1.2.48) from Saccharomyces cerevisiae (see paper)
    35% identity, 95% coverage of query (163 bits)

orf19.6305 hydroxytrimethyllysine aldolase from Candida albicans (see paper)
    36% identity, 80% coverage of query (162 bits)

GLY1 L-threonine aldolase from Candida albicans (see paper)
    37% identity, 76% coverage of query (160 bits)

O13427 low-specificity L-threonine aldolase (EC 4.1.2.48) from Candida albicans (see paper)
    36% identity, 76% coverage of query (157 bits)

GLY1 / CAA06545.1 threonine aldolase from Eremothecium gossypii (see paper)
    35% identity, 80% coverage of query (145 bits)

VRTJ_PENAE / D7PHZ0 Aldolase vrtJ; Viridicatumtoxin synthesis protein J; EC 4.1.2.- from Penicillium aethiopicum (see 4 papers)
    37% identity, 92% coverage of query (139 bits)

TOXG_COCCA / Q9UW18 Alanine racemase TOXG; TOX2 HC-toxin biosynthesis cluster protein TOXG; EC 5.1.1.1 from Cochliobolus carbonum (Maize leaf spot fungus) (Bipolaris zeicola) (see 2 papers)
    32% identity, 96% coverage of query (127 bits)

Build an alignment

Build an alignment for 3608752 and 23 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

AO353_07670 L-threonine aldolase (EC 4.1.2.5) from Pseudomonas fluorescens FW300-N2E3
    29% identity, 90% coverage of query (82.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory