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Searching for up to 100 curated homologs for 3609057 FitnessBrowser__Dino:3609057 (303 a.a.)

Found high-coverage hits (≥70%) to 29 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Ac3H11_603 L-2-keto-3-deoxyarabonate dehydratase (EC 4.2.1.43) from Acidovorax sp. GW101-3H11
    59% identity, 96% coverage of query (337 bits)

BPHYT_RS22715 L-2-keto-3-deoxyarabonate dehydratase (EC 4.2.1.43) from Burkholderia phytofirmans PsJN
    55% identity, 98% coverage of query (316 bits)

HSERO_RS06870 L-2-keto-3-deoxyarabonate dehydratase (EC 4.2.1.43) from Herbaspirillum seropedicae SmR1
    54% identity, 99% coverage of query (312 bits)

KDADA_AZOBR / Q1JUQ0 L-2-keto-3-deoxyarabonate dehydratase; L-KDA dehydratase; 2-dehydro-3-deoxy-L-arabinonate dehydratase; L-2-keto-3-deoxyarabinonate dehydratase; EC 4.2.1.43 from Azospirillum brasilense (see 2 papers)
Q1JUQ0 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43) from Azospirillum brasilense (see 2 papers)
    57% identity, 99% coverage of query (307 bits)

Q7D313 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
    33% identity, 71% coverage of query (89.0 bits)

Build an alignment

Build an alignment for 3609057 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

dapA / Q65JG7 dihydrodipicolinate synthase subunit (EC 4.3.3.7) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) (see paper)
    25% identity, 93% coverage of query (83.2 bits)

dapA / Q04796 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacillus subtilis (strain 168) (see paper)
    27% identity, 94% coverage of query (78.2 bits)

O67216 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Aquifex aeolicus (see paper)
    25% identity, 93% coverage of query (77.8 bits)

dapA2 dihydrodipicolinate synthase; EC 4.2.1.52 from Bacillus anthracis (see paper)
    27% identity, 75% coverage of query (74.3 bits)

Q8RBI5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
    24% identity, 73% coverage of query (69.7 bits)

3qfeA Crystal structures of a putative dihydrodipicolinate synthase family protein from coccidioides immitis
    26% identity, 83% coverage of query (69.3 bits)

1o5kA / Q9X1K9 Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
    24% identity, 95% coverage of query (67.8 bits)

DAPA_THEMA / Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
    24% identity, 95% coverage of query (67.8 bits)

8u8wA / A0A0H3FJT8 Crystal structure of n-acetylneuraminate lyase (nana) from klebsiella aerogenes (pyruvate and halides bound)
    24% identity, 95% coverage of query (67.4 bits)

3l21B The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis - dhdps- a204r
    28% identity, 73% coverage of query (64.3 bits)

5j5dA / P9WP25 Crystal structure of dihydrodipicolinate synthase from mycobacterium tuberculosis in complex with alpha-ketopimelic acid (see paper)
    28% identity, 73% coverage of query (63.9 bits)

DAPA_MYCTU / P9WP25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
    28% identity, 73% coverage of query (63.9 bits)

1xxxA Crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis
    28% identity, 73% coverage of query (63.9 bits)

nanA sialic acid lyase from Clostridium perfringens (see paper)
    22% identity, 90% coverage of query (62.4 bits)

nanA / Q9S4K9 N-acetylneuraminate lyase (EC 4.1.3.3) from Clostridium perfringens (strain 13 / Type A) (see 6 papers)
nanA / GB|CAA73375.1 N-acetylneuraminate lyase; EC 4.1.3.3 from Clostridium perfringens (see 4 papers)
    22% identity, 90% coverage of query (61.6 bits)

Q9S4K9 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Clostridium perfringens (strain 13 / Type A)
    22% identity, 90% coverage of query (61.6 bits)

2wpbA / P0A6L4 Crystal structure of the e192n mutant of e. Coli n-acetylneuraminic acid lyase in complex with pyruvate and the inhibitor (2r,3r)-2,3,4- trihydroxy-n,n-dipropylbutanamide in space group p21 crystal form i (see paper)
    23% identity, 90% coverage of query (61.2 bits)

dapA / P19808 dihydropicolinate synthase subunit (EC 4.3.3.7) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
P19808 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Corynebacterium glutamicum (see paper)
dapA / CAA79714.1 dihydrodipicolinate synthase from Corynebacterium glutamicum (see paper)
    26% identity, 82% coverage of query (55.1 bits)

Q9FVC8 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Arabidopsis thaliana (see paper)
    23% identity, 93% coverage of query (51.6 bits)

5ktlA / Q3M723 Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria anabaena variabilis. (see paper)
    22% identity, 76% coverage of query (49.3 bits)

Q3M723 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Trichormus variabilis (see paper)
    22% identity, 76% coverage of query (49.3 bits)

7mdsA Crystal structure of atdhdps1 in complex with mbdta-2
    24% identity, 70% coverage of query (47.0 bits)

6vvhBBB / Q9LZX6 thaliana dihydrodipicolinate synthase isoform 1 (dhdps1) in complex with lysine (see paper)
    24% identity, 70% coverage of query (46.6 bits)

4hnnF / D7U7T8 Dihydrodipicolinate synthase from the common grapevine with pyruvate and lysine (see paper)
    22% identity, 93% coverage of query (43.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory