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Searching for up to 100 curated homologs for 3609389 FitnessBrowser__Dino:3609389 (273 a.a.)

Found high-coverage hits (≥70%) to 56 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PGA1_c21860 Histidinol-phosphatase [alternative form] (EC 3.1.3.15) from Phaeobacter inhibens BS107
    65% identity, 85% coverage of query (290 bits)

AZOBR_RS03845 Histidinol-phosphatase [alternative form] (EC 3.1.3.15) from Azospirillum brasilense Sp245
    44% identity, 93% coverage of query (191 bits)

Ga0059261_2035 Histidinol-phosphatase [alternative form] (EC 3.1.3.15) from Sphingomonas koreensis DSMZ 15582
    47% identity, 87% coverage of query (184 bits)

G7J7Q5 histidinol-phosphatase (EC 3.1.3.15); inositol-phosphate phosphatase (EC 3.1.3.25) from Medicago truncatula (see paper)
    38% identity, 92% coverage of query (175 bits)

HISN7 / Q6NPM8 histidinol phosphate phosphatase (EC 3.1.3.15; EC 3.1.3.93; EC 3.1.3.25) from Arabidopsis thaliana (see 2 papers)
HIS7_ARATH / Q6NPM8 Bifunctional phosphatase IMPL2, chloroplastic; Histidinol-phosphatase; Histidinol-phosphate phosphatase; HPP; Inositol-phosphate phosphatase; L-galactose 1-phosphate phosphatase; Protein HISTIDINE BIOSYNTHESIS 7; Protein MYO-INOSITOL MONOPHOSPHATASE-LIKE 2; EC 3.1.3.15; EC 3.1.3.25; EC 3.1.3.93 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q6NPM8 histidinol-phosphatase (EC 3.1.3.15); inositol-phosphate phosphatase (EC 3.1.3.25) from Arabidopsis thaliana (see 4 papers)
    38% identity, 94% coverage of query (174 bits)

5eq9B / G7J7Q5 Crystal structure of medicago truncatula histidinol-phosphate phosphatase (mthpp) in complex with l-histidinol phosphate and mg2+ (see paper)
    38% identity, 92% coverage of query (169 bits)

5t3jA Histidinol phosphate phosphatase(hpp) soaked with selenourea for 10 min
    39% identity, 86% coverage of query (169 bits)

5eq8A Crystal structure of medicago truncatula histidinol-phosphate phosphatase (mthpp) in complex with l-histidinol
    38% identity, 92% coverage of query (169 bits)

hisN / Q8NS80 histidinol-phosphatase (EC 3.1.3.15) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 2 papers)
HISN_CORGL / Q8NS80 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
Q8NS80 histidinol-phosphatase (EC 3.1.3.15) from Corynebacterium glutamicum (see 2 papers)
    33% identity, 88% coverage of query (119 bits)

HISN_STRCO / Q9K4B1 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    33% identity, 93% coverage of query (108 bits)

5zonA / P95189 Histidinol phosphate phosphatase from mycobacterium tuberculosis (see paper)
    33% identity, 88% coverage of query (107 bits)

HISN_MYCTU / P95189 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P95189 histidinol-phosphatase (EC 3.1.3.15) from Mycobacterium tuberculosis (see paper)
    33% identity, 88% coverage of query (107 bits)

5yhtA Crystal structure of a phosphatase from mycobacterium tuberculosis in complex with its substrate
    33% identity, 88% coverage of query (107 bits)

SUHB_BURCJ / B4ED80 Putative Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) (see paper)
    31% identity, 81% coverage of query (90.9 bits)

Build an alignment

Build an alignment for 3609389 and 14 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

Q5U789 L-galactose 1-phosphate phosphatase (EC 3.1.3.93) from Actinidia deliciosa (see paper)
    29% identity, 84% coverage of query (89.0 bits)

IMPA_MYCS2 / A0QX86 Inositol-1-monophosphatase ImpA; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
A0QX86 fructose-bisphosphatase (EC 3.1.3.11); inositol-phosphate phosphatase (EC 3.1.3.25) from Mycolicibacterium smegmatis (see paper)
    32% identity, 81% coverage of query (84.3 bits)

SUHB_SALT1 / A0A0F6B4W4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Salmonella typhimurium (strain 14028s / SGSC 2262) (see paper)
    30% identity, 80% coverage of query (84.3 bits)

6ib8B / P0ADG4 Structure of a complex of suhb and nusa ar2 domain (see paper)
    30% identity, 80% coverage of query (83.2 bits)

SsyA / b2533 Nus factor SuhB (EC 3.1.3.25; EC 3.1.3.19) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
suhB / P0ADG4 Nus factor SuhB (EC 3.1.3.25; EC 3.1.3.19) from Escherichia coli (strain K12) (see 16 papers)
SUHB_ECOLI / P0ADG4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Escherichia coli (strain K12) (see 14 papers)
    30% identity, 80% coverage of query (83.2 bits)

6tqoT Rrn anti-termination complex
    30% identity, 81% coverage of query (83.2 bits)

B3GK03 L-galactose 1-phosphate phosphatase (EC 3.1.3.93) from Nicotiana tabacum (see paper)
    29% identity, 81% coverage of query (82.8 bits)

2qflA Structure of suhb: inositol monophosphatase and extragenic suppressor from e. Coli
    31% identity, 80% coverage of query (82.4 bits)

IMPA_MYCTU / O53907 Probable inositol 1-monophosphatase ImpA; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    34% identity, 81% coverage of query (81.6 bits)

Q8NS79 histidinol-phosphatase (EC 3.1.3.15) from Corynebacterium glutamicum (see paper)
    31% identity, 81% coverage of query (80.9 bits)

VTC4 / Q9M8S8 L-galactose-1-phosphate phosphatase//inositol or phosphatidylinositol phosphatase (EC 3.1.3.25; EC 3.1.3.93) from Arabidopsis thaliana (see 3 papers)
VTC4_ARATH / Q9M8S8 Inositol-phosphate phosphatase; L-galactose 1-phosphate phosphatase; Myo-inositol monophosphatase; EC 3.1.3.25; EC 3.1.3.93 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9M8S8 inositol-phosphate phosphatase (EC 3.1.3.25); L-galactose 1-phosphate phosphatase (EC 3.1.3.93) from Arabidopsis thaliana (see 5 papers)
    29% identity, 84% coverage of query (79.7 bits)

TM1415 / O33832 inositol monophosphatase subunit (EC 3.1.3.25) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
BSUHB_THEMA / O33832 Fructose-1,6-bisphosphatase/inositol-1-monophosphatase; FBPase/IMPase; Inositol-1-phosphatase; I-1-Pase; EC 3.1.3.11; EC 3.1.3.25 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 3 papers)
O33832 inositol-phosphate phosphatase (EC 3.1.3.25) from Thermotoga maritima (see paper)
2p3nA / O33832 Thermotoga maritima impase tm1415 (see paper)
    26% identity, 81% coverage of query (79.3 bits)

3lv0A / A0A0H3M6W8 Crystal structure of extragenic suppressor protein suhb from bartonella henselae, native
    31% identity, 81% coverage of query (79.0 bits)

IMP1_SOLLC / P54926 Inositol monophosphatase 1; IMP 1; IMPase 1; LeIMP1; Inositol-1(or 4)-monophosphatase 1; EC 3.1.3.25 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
    28% identity, 80% coverage of query (78.2 bits)

3luzA Crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacement
    29% identity, 81% coverage of query (78.2 bits)

B3DFH0 inositol-phosphate phosphatase (EC 3.1.3.25) from Hordeum vulgare (see paper)
    31% identity, 75% coverage of query (77.0 bits)

3luzB / A0A0H3M6W8 Crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacement (see paper)
    28% identity, 81% coverage of query (75.9 bits)

IMP3_SOLLC / P54928 Inositol monophosphatase 3; IMP 3; IMPase 3; LeIMP3; Inositol-1(or 4)-monophosphatase 3; EC 3.1.3.25 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
    28% identity, 84% coverage of query (75.5 bits)

IMP2_SOLLC / P54927 Inositol monophosphatase 2; IMP 2; IMPase 2; LeIMP2; Inositol-1(or 4)-monophosphatase 2; EC 3.1.3.25 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see 2 papers)
    30% identity, 84% coverage of query (75.1 bits)

IMPA1_CAEEL / Q19420 Inositol monophosphatase ttx-7; IMP; IMPase; Abnormal thermotaxis protein 7; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase; EC 3.1.3.25; EC 3.1.3.94 from Caenorhabditis elegans (see 2 papers)
    27% identity, 77% coverage of query (74.3 bits)

SUHB_PSEAE / Q9HXI4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
    29% identity, 81% coverage of query (73.2 bits)

IMPA2_MOUSE / Q91UZ5 Inositol monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2; EC 3.1.3.25 from Mus musculus (Mouse) (see paper)
Q91UZ5 inositol-phosphate phosphatase (EC 3.1.3.25) from Mus musculus (see paper)
    30% identity, 92% coverage of query (69.3 bits)

2cziA / O14732 Crystal structure of human myo-inositol monophosphatase 2 (impa2) with calcium and phosphate ions (see paper)
    30% identity, 92% coverage of query (68.6 bits)

IMPA2 / O14732 inositol monophosphatase 2 monomer (EC 3.1.3.25) from Homo sapiens (see 5 papers)
IMPA2_HUMAN / O14732 Inositol monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2; EC 3.1.3.25 from Homo sapiens (Human) (see 3 papers)
    30% identity, 78% coverage of query (68.2 bits)

SUHB_BACSU / Q45499 Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25; EC 3.1.3.5 from Bacillus subtilis (strain 168) (see paper)
    26% identity, 88% coverage of query (67.8 bits)

A0A1I9GET0 inositol-phosphate phosphatase (EC 3.1.3.25) from Staphylococcus aureus (see 2 papers)
    27% identity, 85% coverage of query (63.5 bits)

QAX_NEUCR / P11634 Quinic acid degradation cluster protein x from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 6 papers)
    27% identity, 70% coverage of query (58.5 bits)

IMPL1_ARATH / Q94F00 Phosphatase IMPL1, chloroplastic; Protein MYO-INOSITOL MONOPHOSPHATASE-LIKE 1; EC 3.1.3.25 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q94F00 inositol-phosphate phosphatase (EC 3.1.3.25) from Arabidopsis thaliana (see 3 papers)
    26% identity, 79% coverage of query (57.4 bits)

2bjiA / P20456 High resolution structure of myo-inositol monophosphatase, the target of lithium therapy (see paper)
    25% identity, 71% coverage of query (56.6 bits)

IMPA1_BOVIN / P20456 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Bos taurus (Bovine) (see 2 papers)
    25% identity, 71% coverage of query (56.2 bits)

5dw8A Crystal structure of 2'amp bound saimpase-ii
    26% identity, 71% coverage of query (55.5 bits)

IMPA1_RAT / P97697 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Rattus norvegicus (Rat) (see 2 papers)
P97697 inositol-phosphate phosphatase (EC 3.1.3.25) from Rattus norvegicus (see 2 papers)
    27% identity, 80% coverage of query (54.3 bits)

5j16A Crystal structure of inositol monophosphate bound saimpase-ii
    25% identity, 70% coverage of query (52.4 bits)

4as5A / O55023 Structure of mouse inositol monophosphatase 1 (see paper)
    24% identity, 76% coverage of query (52.0 bits)

pssB / AAA81571.1 pssB from Rhizobium leguminosarum (see paper)
    28% identity, 71% coverage of query (52.0 bits)

IMPA1_MOUSE / O55023 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Mus musculus (Mouse) (see 3 papers)
O55023 inositol-phosphate phosphatase (EC 3.1.3.25) from Mus musculus (see 2 papers)
    23% identity, 76% coverage of query (51.2 bits)

6b63A Impase (af2372) with 25 mm asp
    23% identity, 80% coverage of query (43.1 bits)

6b60A Impase (af2372) with 25 mm glutamate
    23% identity, 80% coverage of query (43.1 bits)

imp / O30298 fructose-1,6-bisphosphatase/inositol-1-monophosphatase (EC 3.1.3.11; EC 3.1.3.25) from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see 5 papers)
BSUHB_ARCFU / O30298 Fructose-1,6-bisphosphatase/inositol-1-monophosphatase; FBPase/IMPase; Inositol-1-phosphatase; I-1-Pase; EC 3.1.3.11; EC 3.1.3.25 from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see 3 papers)
O30298 nocturnin (EC 3.1.3.108); fructose-bisphosphatase (EC 3.1.3.11); inositol-phosphate phosphatase (EC 3.1.3.25) from Archaeoglobus fulgidus (see 4 papers)
6b5zA / O30298 Impase (af2372) with 25 mm asp
    23% identity, 80% coverage of query (43.1 bits)

1lbzA Crystal structure of a complex (p32 crystal form) of dual activity fbpase/impase (af2372) from archaeoglobus fulgidus with 3 calcium ions and fructose-1,6 bisphosphate
    23% identity, 80% coverage of query (43.1 bits)

1lbyA Crystal structure of a complex (p32 crystal form) of dual activity fbpase/impase (af2372) from archaeoglobus fulgidus with 3 manganese ions, fructose-6-phosphate, and phosphate ion
    23% identity, 80% coverage of query (43.1 bits)

1lbxA Crystal structure of a ternary complex of dual activity fbpase/impase (af2372) from archaeoglobus fulgidus with calcium ions and d-myo- inositol-1-phosphate
    23% identity, 80% coverage of query (43.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory