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Searching for up to 100 curated homologs for 3609747 FitnessBrowser__Dino:3609747 (287 a.a.)

Found high-coverage hits (≥70%) to 48 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.1.35 / G3LHZ0 GlpP, component of Glycerol uptake porter, GlpSTPQV from Rhizobium leguminosarum bv. viciae
    73% identity, 100% coverage of query (399 bits)

Ac3H11_793 ABC transporter for Glycerol, permease component 1 from Acidovorax sp. GW101-3H11
    59% identity, 98% coverage of query (320 bits)

Dshi_0548 ABC transporter for Xylitol, permease component 1 from Dinoroseobacter shibae DFL-12
    32% identity, 75% coverage of query (114 bits)

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Build an alignment for 3609747 and 3 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 3.A.1.1.37 / Q9WYB4 Predicted arabinoside porter. Regulated by arabinose-responsive regulator AraR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    29% identity, 95% coverage of query (100 bits)

TC 3.A.1.1.15 / Q97ZC2 TreT, component of Trehalose porter from Sulfolobus solfataricus (see paper)
    28% identity, 90% coverage of query (93.6 bits)

SM_b20326 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 1 (ThuF) from Sinorhizobium meliloti 1021
TC 3.A.1.1.17 / Q9R9Q6 ThuF aka RB0312 aka SMB20326, component of Trehalose/maltose/sucrose porter (trehalose inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 3 papers)
    29% identity, 94% coverage of query (88.2 bits)

TC 3.A.1.1.20 / Q7WWQ9 Transmembrane permease MsmF, component of The fructooligosaccharide porter, MsmEFGK from Lactobacillus acidophilus (see 2 papers)
msmF / GI|33149339 transmembrane permease MsmF from Lactobacillus acidophilus (see paper)
    25% identity, 91% coverage of query (88.2 bits)

SMc02872 ABC transporter for N-Acetyl-D-glucosamine, permease protein 1 from Sinorhizobium meliloti 1021
    30% identity, 91% coverage of query (85.1 bits)

TC 3.A.1.1.11 / Q93KC0 TogM, component of Saturated and unsaturated oligogalacturonide transporter, TogMNAB (transports di- to tetrasaccharide pectin degradation products which consist of D-galacuronate, sometimes with 4-deoxy-L-threo-5-hexosulose uronate at the reducing end of the oligosaccharide) (Hugouvieux-Cotte-Pattat et al. 2001). Regulated by pectin utilization regulator KdgR from Erwinia chrysanthemi (see paper)
    27% identity, 82% coverage of query (84.3 bits)

TC 3.A.1.1.19 / Q8L125 PalF, component of Platinose (isomaltulose) (6-O-α-D-glucopyranosyl-D-fructofuranose) porter from Agrobacterium tumefaciens (see 3 papers)
    26% identity, 96% coverage of query (83.6 bits)

TC 3.A.1.1.25 / Q72H67 Maltose transport system permease protein malF aka TT_C1628, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    29% identity, 78% coverage of query (82.0 bits)

SM_b21104 ABC transporter for L-Fucose, permease component 1 from Sinorhizobium meliloti 1021
    29% identity, 80% coverage of query (81.6 bits)

HSERO_RS17005 ABC transporter for D-sorbitol/xylitol, permease component 1 from Herbaspirillum seropedicae SmR1
    24% identity, 85% coverage of query (79.7 bits)

mtlF / Q4KC56 polyol ABC-type transporter permease component MtlF from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    25% identity, 97% coverage of query (79.7 bits)

TC 3.A.1.1.41 / G4FGN7 ABC-type transporter, integral membrane subunit, component of Trehalose porter. Also binds sucrose (Boucher and Noll, 2011). Induced by glucose and trehalose. Directly regulated by trehalose-responsive regulator TreR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    27% identity, 83% coverage of query (79.7 bits)

MALF_THELN / O51924 Trehalose/maltose transport system permease protein MalF from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 3 papers)
    28% identity, 93% coverage of query (78.6 bits)

sugA / P9WG03 ABC-type trehalose transporter integral membrane protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGA_MYCTU / P9WG03 Trehalose transport system permease protein SugA from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
TC 3.A.1.1.31 / O50452 PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGA, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
    29% identity, 99% coverage of query (77.0 bits)

TC 3.A.1.1.50 / Q5SLB6 Sugar ABC transporter, permease protein, component of Probable glycerophosphocholine (GPC) uptake porter (Chandravanshi et al. 2016). The system may include a receptor and three membrane proteins (of 378 aas and 6 TMSs, 299 aas and 7 TMSs, and 113 aas and 3 TMSs (?). The ATPase has not been identified from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
    25% identity, 83% coverage of query (75.5 bits)

Q6MNM0 ABC-type maltose transporter (EC 7.5.2.1) from Bdellovibrio bacteriovorus (see paper)
TC 3.A.1.1.51 / Q6MNM0 Maltose - maltoheptose transporter, MalEFGK from Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100)
    26% identity, 82% coverage of query (75.1 bits)

DASB_STRCO / Q9K490 Diacetylchitobiose uptake system permease protein DasB from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    25% identity, 76% coverage of query (75.1 bits)

TC 3.A.1.1.49 / O30492 MtlF, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
    24% identity, 97% coverage of query (74.7 bits)

Ac3H11_2943 ABC transporter for D-Sorbitol, permease component 2 from Acidovorax sp. GW101-3H11
    28% identity, 79% coverage of query (74.3 bits)

TC 3.A.1.1.33 / Q8KN18 Putative sugar transporter integral membrane protein, component of The N,N'-diacetylchitobiose uptake transporter, DasABC/MsiK (MsiK energizes several ABC transporters (see 3.A.1.1.23)) from Streptomyces sp. 139 (see 2 papers)
    25% identity, 84% coverage of query (74.3 bits)

PS417_12710 ABC transporter for D-Mannitol and D-Sorbitol, permease component 2 from Pseudomonas simiae WCS417
    24% identity, 97% coverage of query (73.6 bits)

TC 3.A.1.1.27 / Q8DT27 MalF, component of Maltose/Maltotriose/maltodextrin (up to 7 glucose units) transporters MalXFGK (MsmK (3.A.1.1.28) can probably substitute for MalK; Webb et al., 2008) from Streptococcus mutans (see paper)
    23% identity, 94% coverage of query (73.6 bits)

PS417_22140 glucose/xylose ABC transporter, permease component 2 from Pseudomonas simiae WCS417
    26% identity, 86% coverage of query (73.6 bits)

SM_b21220 ABC transporter for D-Glucosamine, permease component 2 from Sinorhizobium meliloti 1021
    31% identity, 77% coverage of query (72.0 bits)

TC 3.A.1.1.30 / Q88P37 GtsB (GLcF), component of Glucose porter, GtsABCD from Pseudomonas putida (strain KT2440) (see paper)
    25% identity, 84% coverage of query (72.0 bits)

AO356_00020 ABC transporter for D-Sorbitol, permease component 2 from Pseudomonas fluorescens FW300-N2C3
    25% identity, 97% coverage of query (71.6 bits)

PfGW456L13_1895 ABC transporter for D-Galactose and D-Glucose, permease component 1 from Pseudomonas fluorescens GW456-L13
    26% identity, 86% coverage of query (71.6 bits)

NGCF_STRCO / O50500 Diacetylchitobiose uptake system permease protein NgcF from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    28% identity, 78% coverage of query (71.2 bits)

7cagA / A0R2C2 Mycobacterium smegmatis lpqy-sugabc complex in the catalytic intermediate state (see paper)
    26% identity, 99% coverage of query (71.2 bits)

BPHYT_RS16110 ABC transporter for D-Sorbitol, permease component 2 from Burkholderia phytofirmans PsJN
    25% identity, 99% coverage of query (71.2 bits)

TC 3.A.1.1.22 / Q9X0T0 MalF1; aka Maltose ABC transporter, permease protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
    28% identity, 86% coverage of query (70.9 bits)

TC 3.A.1.1.28 / Q00750 MsmF aka SMU.879, component of The raffinose/stachyose transporter, MsmEFGK (MalK (3.A.1.1.27) can probably substitute for MsmK; Webb et al., 2008). This system may also transport melibiose, isomaltotriose and sucrose as well as isomaltosaccharides from Streptococcus mutans (see 2 papers)
    26% identity, 87% coverage of query (69.7 bits)

TC 3.A.1.1.48 / D6ZW63 MalF-type ABC sugar transport systems permease component, component of The lacto-N-biose I (LNB; Gal β-1,3-GlcNAc)/galacto-N-biose (GNB; Gal β-1,3-GalNAc) transporter from Bifidobacterium longum subsp. longum (strain JDM301)
    25% identity, 99% coverage of query (69.3 bits)

YcjO / b1311 putative ABC transporter membrane subunit YcjO from Escherichia coli K-12 substr. MG1655 (see 2 papers)
TC 3.A.1.1.46 / P0AFR7 Inner membrane ABC transporter permease protein YcjO, component of Probable glucoside uptake porter, YcjNOPV from Escherichia coli (strain K12)
    26% identity, 79% coverage of query (69.3 bits)

TC 3.A.1.1.14 / Q97UF4 AraT, component of Arabinose, fructose, xylose porter from Sulfolobus solfataricus (see paper)
    26% identity, 82% coverage of query (67.4 bits)

TC 3.A.1.1.44 / Q9KZ07 Putative maltose permease, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    24% identity, 100% coverage of query (67.0 bits)

PGA1_c13200 ABC transporter for D-Sorbitol, permease component 2 from Phaeobacter inhibens BS107
    24% identity, 83% coverage of query (66.2 bits)

TC 3.A.1.1.7 / O51924 MalF, component of Maltose/trehalose porter from Thermococcus litoralis (see paper)
    29% identity, 93% coverage of query (65.9 bits)

TC 3.A.1.1.45 / Q8NMV4 ABC-type sugar transport system, permease component, component of Maltose transporter, MusEFGKI from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
    24% identity, 87% coverage of query (65.5 bits)

PGA1_c27940 N-Acetyl-D-glucosamine ABC transport system, permease component 1 from Phaeobacter inhibens BS107
    27% identity, 75% coverage of query (65.1 bits)

MELD_BACSU / O34706 Melibiose/raffinose/stachyose import permease protein MelD from Bacillus subtilis (strain 168) (see paper)
    24% identity, 96% coverage of query (64.7 bits)

BWI76_RS01825 maltose ABC transporter, permease component 1 (MalF) from Klebsiella michiganensis M5al
    25% identity, 80% coverage of query (64.7 bits)

Ac3H11_2064 glucose ABC transporter, permease component 1 from Acidovorax sp. GW101-3H11
    23% identity, 85% coverage of query (64.3 bits)

TC 3.A.1.1.4 / P29823 LacF, component of Lactose porter from Agrobacterium radiobacter (see paper)
    25% identity, 83% coverage of query (62.4 bits)

Dshi_1651 glucose/maltose/trehalose/sucrose ABC transporter, permease component 1 from Dinoroseobacter shibae DFL-12
    21% identity, 81% coverage of query (61.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory