Sites on a Tree

 

Searching for up to 100 curated homologs for 3610288 FitnessBrowser__Dino:3610288 (244 a.a.)

Found high-coverage hits (≥70%) to 3 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YbhL / b0786 Bax1-I family protein YbhL from Escherichia coli K-12 substr. MG1655 (see 5 papers)
TC 1.A.14.2.2 / P0AAC4 The YbhL (AceP) protein. Possibly a pmf-dependent acetate uptake transporter. [14C]Acetate uptake was inhibited by CCCP as well as cold acetate, serine, α-ketoglutarate, lactate, and succinate (M. Inouye, personal communication) from Escherichia coli (see 4 papers)
    44% identity, 99% coverage of query (170 bits)

TC 1.A.14.2.3 / O31539 The 7 TMS proton-sensitive Ca2+ leak channel, YetJ.  The activity and high resolution 3-d structure have been determined from Bacillus subtilis (see paper)
    31% identity, 72% coverage of query (51.6 bits)

Build an alignment

Build an alignment for 3610288 and 2 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

YccA / b0970 modulator of FtsH protease from Escherichia coli K-12 substr. MG1655 (see 8 papers)
YCCA_ECOLI / P0AAC6 Modulator of FtsH protease YccA from Escherichia coli (strain K12) (see 4 papers)
TC 1.A.14.2.1 / P0AAC6 The YccA protein, an inhibitor of FtsH. May share a similar mechanism of action as BI-1 in regulation apoptsis upon prolonged secretion stress from Escherichia coli (see 9 papers)
    26% identity, 83% coverage of query (45.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory