Searching for up to 100 curated homologs for 5208200 FitnessBrowser__PV4:5208200 (324 a.a.)
Found high-coverage hits (≥70%) to 66 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
FhuC / b0151 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FhuC / P07821 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see paper)
FHUC_ECOLI / P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.3 / P07821 FhuC aka B0151, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 6 papers)
fhuC / GB|BAB96727.2 ferrichrome transport ATP-binding protein FhuC; EC 3.6.3.34 from Escherichia coli K12 (see 8 papers)
41% identity, 77% coverage of query (192 bits)
FepC / b0588 ferric enterobactin ABC transporter ATP binding subunit (EC 7.2.2.17) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
FepC / P23878 ferric enterobactin ABC transporter ATP binding subunit (EC 7.2.2.17) from Escherichia coli (strain K12) (see 3 papers)
FEPC_ECOLI / P23878 Ferric enterobactin transport ATP-binding protein FepC; EC 7.2.2.17 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.2 / P23878 FepC aka B0588, component of Iron (Fe3+)-enterobactin porter from Escherichia coli (see 3 papers)
38% identity, 73% coverage of query (182 bits)
TC 3.A.1.14.8 / Q8GRB0 PvuE, component of The iron-vibrioferrin uptake porter from Vibrio parahaemolyticus (see paper)
36% identity, 76% coverage of query (176 bits)
FecE / b4287 ferric citrate ABC transporter ATP binding subunit (EC 7.2.2.18) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
FecE / P15031 ferric citrate ABC transporter ATP binding subunit (EC 7.2.2.18) from Escherichia coli (strain K12) (see 2 papers)
FECE_ECOLI / P15031 Fe(3+) dicitrate transport ATP-binding protein FecE; Iron(III) dicitrate transport ATP-binding protein FecE; EC 7.2.2.18 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.1 / P15031 Fe(3+) dicitrate transport ATP-binding protein FecE, component of Iron (Fe3+) or ferric-dicitrate porter from Escherichia coli (strain K12) (see 4 papers)
fecE / GB|AAC77243.1 iron(III) dicitrate transport ATP-binding protein FecE from Escherichia coli K12 (see 6 papers)
37% identity, 76% coverage of query (172 bits)
FPUD_BACAN / Q81V82 Petrobactin import ATP-binding protein FpuD; EC 7.2.2.- from Bacillus anthracis (see paper)
37% identity, 76% coverage of query (171 bits)
TC 3.A.1.14.7 / Q9X665 FhuC aka FhuA, component of Iron (Fe3+)-hydroxamate porter (transports Fe3+-ferrichrome and Fe3+-ferrioxamine B with FhuD1, and these compounds plus aerobactin and coprogen with FhuD2) (see 2 papers)
37% identity, 73% coverage of query (170 bits)
YUSV_BACSU / O32188 Probable siderophore transport system ATP-binding protein YusV from Bacillus subtilis (strain 168) (see 2 papers)
37% identity, 76% coverage of query (166 bits)
TC 3.A.1.14.19 / Q93SS1 Hemin import ATP-binding protein hmuV, component of Heme uptake porter, HugBCD (Villarreal et al., 2008); also called HmuTUV from Plesiomonas shigelloides (see paper)
38% identity, 76% coverage of query (166 bits)
TC 3.A.1.14.10 / Q99YA4 Putative ABC transporter aka SiaC, component of The heme porter, Shp/SiaABC (HtsABC). Shp is a cell surface heme binding protein that transfers the heme directly to HstA (Nygaard et al., 2006). The crystal structure of the heme binding domain of Shp has been solved (Aranda et al., 2007). HtsABC is required for the uptake of staphyloferrin A (Beasley et al. 2009). The Shp cell surface heme receptor feeds iron-heme to the transporter in preparation for uptake from Streptococcus pyogenes serotype M1 (see 2 papers)
38% identity, 72% coverage of query (164 bits)
fhuC / GI|2832798 ferrichrome transport ATP-binding protein FhuC from Bacillus subtilis (see paper)
34% identity, 76% coverage of query (162 bits)
TC 3.A.1.14.14 / Q9A197 Putative ferrichrome ABC transporter aka SiuA aka Spy0386, component of The Fe3+ /Fe3+ferrichrome/Fe3+heme uptake porter; SiuABDG (FTSABCD) from Streptococcus pyogenes serotype M1 (see 2 papers)
36% identity, 77% coverage of query (162 bits)
TC 3.A.1.14.6 / Q9RCF3 ViuC, component of The iron-vibriobactin/enterobactin uptake porter from Vibrio cholerae (see 2 papers)
37% identity, 73% coverage of query (162 bits)
TC 3.A.1.14.4 / Q47087 CbrD, component of Iron-chrysobactine porter from Erwinia chrysanthemi (see paper)
cbrD / GB|CAA60669.1 achromobactin ABC transporter, ATP-binding protein CbrD from Erwinia chrysanthemi str. 3937 (see paper)
37% identity, 74% coverage of query (162 bits)
FPUC_BACAN / Q81LM1 Petrobactin import ATP-binding protein FpuC; EC 7.2.2.- from Bacillus anthracis (see paper)
35% identity, 73% coverage of query (159 bits)
TC 3.A.1.14.5 / Q56993 HmuV aka YPO0279 aka Y0539, component of Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle from Yersinia pestis (see 4 papers)
hmuV hemin import ATP-binding protein hmuV; EC 3.6.3.- from Yersinia pestis KIM (see paper)
37% identity, 76% coverage of query (157 bits)
BTUDA_HALSA / Q9HQ18 Cobalamin import ATP-binding protein BtuD; Vitamin B12-transporting ATPase; EC 7.6.2.8 from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) (see paper)
37% identity, 76% coverage of query (155 bits)
YCLP_BACSU / P94420 Petrobactin import ATP-binding protein YclP; EC 7.2.2.- from Bacillus subtilis (strain 168) (see paper)
34% identity, 71% coverage of query (152 bits)
TC 3.A.1.14.16 / A8GDS6 HemV, component of The heme-specific uptake porter, HemTUV from Serratia proteamaculans (strain 568)
38% identity, 77% coverage of query (148 bits)
TC 3.A.1.14.18 / Q32AY3 Hemin import ATP-binding protein hmuV, component of The heme uptake porter, ShuTUV (Burkhard and Wilks, 2008). Transports a single heme per reaction cycle (Mattle et al., 2010). (3-d structure of ShuT is known (2RG7) from Shigella dysenteriae serotype 1 (strain Sd197) (see paper)
34% identity, 76% coverage of query (146 bits)
TC 3.A.1.14.20 / Q7W025 Hemin import ATP-binding protein HmuV, component of Heme-iron (hemin) utilization transporter BhuTUV from Bordetella pertussis (see paper)
38% identity, 74% coverage of query (142 bits)
TC 3.A.1.14.21 / O68877 Hemin import ATP-binding protein HmuV, component of The heme uptake porter, PhuTUV (transports one heme per reaction cycle) from Pseudomonas aeruginosa (see 2 papers)
37% identity, 76% coverage of query (142 bits)
TC 3.A.1.14.12 / Q9L177 DesC, component of Desferrioxamine B uptake porter, DesABC from Streptomyces coelicolor (see paper)
33% identity, 74% coverage of query (139 bits)
TC 3.A.1.14.13 / Q9RK11 CchE, component of Ferric iron-coelichelin uptake porter, CchCDEF from Streptomyces coelicolor (see paper)
36% identity, 81% coverage of query (134 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
33% identity, 70% coverage of query (129 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
32% identity, 73% coverage of query (128 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
32% identity, 73% coverage of query (119 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
32% identity, 73% coverage of query (119 bits)
2olkA Abc protein artp in complex with adp-beta-s
32% identity, 73% coverage of query (119 bits)
2oljA Abc protein artp in complex with adp/mg2+
32% identity, 73% coverage of query (119 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
31% identity, 75% coverage of query (113 bits)
7sgrE / Q8FDZ8 Structure of hemolysin a secretion system hlyb/d complex (see paper)
30% identity, 77% coverage of query (107 bits)
8dckA Structure of hemolysin a secretion system hlyb/d complex, atp-bound
30% identity, 77% coverage of query (106 bits)
ABCB7_HUMAN / O75027 Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette transporter 7; ABC transporter 7 protein from Homo sapiens (Human) (see 8 papers)
TC 3.A.1.210.4 / O75027 ABC7 or ABCB7 iron transporter (X-linked sideroblastis anemia protein, XLSA/A (Fujiwara and Harigae 2013)) from Homo sapiens (Human) (see 9 papers)
31% identity, 72% coverage of query (103 bits)
7ch8I Cryo-em structure of p.Aeruginosa mlafebd with adp-v
30% identity, 75% coverage of query (103 bits)
ABC1_MYCTU / O65934 ABC transporter ATP-binding/permease protein Rv1747; EC 7.-.-.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
32% identity, 73% coverage of query (101 bits)
7qkrA / F2QQK6 Cryo-em structure of abc transporter ste6-2p from pichia pastoris with verapamil at 3.2 a resolution (see paper)
32% identity, 73% coverage of query (100 bits)
1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
33% identity, 71% coverage of query (99.0 bits)
HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
33% identity, 71% coverage of query (99.0 bits)
Build an alignment for 5208200 and 38 homologs with ≥ 30% identity
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4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
27% identity, 73% coverage of query (95.9 bits)
8hf7B Cryo-em structure of coma bound to its mature substrate csp peptide
30% identity, 72% coverage of query (94.7 bits)
8hf4A / A0A0H2ZPI8 Cryo-em structure of nucleotide-bound coma at outward-facing state with ec gate closed conformation (see paper)
29% identity, 72% coverage of query (94.4 bits)
sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
29% identity, 75% coverage of query (94.4 bits)
8k7aA Cryo-em structure of nucleotide-bound coma e647q mutant with mg2+
29% identity, 72% coverage of query (92.8 bits)
8hf6A Cryo-em structure of nucleotide-bound coma e647q mutant
29% identity, 72% coverage of query (92.8 bits)
6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
25% identity, 71% coverage of query (92.4 bits)
6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
28% identity, 71% coverage of query (92.0 bits)
6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
28% identity, 71% coverage of query (92.0 bits)
6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
28% identity, 71% coverage of query (92.0 bits)
6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
28% identity, 71% coverage of query (91.7 bits)
6b89A E. Coli lptb in complex with adp and novobiocin
28% identity, 71% coverage of query (91.7 bits)
4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
28% identity, 71% coverage of query (91.7 bits)
8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
28% identity, 77% coverage of query (90.5 bits)
6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
27% identity, 72% coverage of query (90.5 bits)
8hprC Lpqy-sugabc in state 4
28% identity, 73% coverage of query (89.7 bits)
8hprD Lpqy-sugabc in state 4
28% identity, 73% coverage of query (89.7 bits)
8t1pD Heterodimeric abc transporter bmrcd in the occluded conformation bound to adpvi: bmrcd_oc-adpvi
30% identity, 76% coverage of query (88.2 bits)
8fpfD / O07549 Heterodimeric abc transporter bmrcd in the inward-facing conformation bound to atp: bmrcd_if-atp (see paper)
29% identity, 76% coverage of query (87.0 bits)
8fmvD Heterodimeric abc transporter bmrcd in the inward-facing conformation bound to substrate and atp: bmrcd_if-2ht/atp
29% identity, 76% coverage of query (87.0 bits)
ABCB6_MOUSE / Q9DC29 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; EC 7.6.2.5 from Mus musculus (Mouse) (see 7 papers)
30% identity, 71% coverage of query (86.3 bits)
6tejB / A0A100XE85 Structure of apo irtab devoid sid in complex with sybody syb_nl5 (see paper)
32% identity, 71% coverage of query (85.1 bits)
ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
29% identity, 74% coverage of query (84.3 bits)
IRTA_MYCT3 / G7CBF5 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile) (see paper)
30% identity, 80% coverage of query (79.0 bits)
1g6hA / Q58663 Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
27% identity, 71% coverage of query (79.0 bits)
1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter
27% identity, 71% coverage of query (78.6 bits)
4q4aA / Q9WYC3 Improved model of amp-pnp bound tm287/288 (see paper)
27% identity, 75% coverage of query (77.4 bits)
6qv0A Structure of atp-bound outward-facing tm287/288 in complex with sybody sb_tm35
27% identity, 75% coverage of query (77.0 bits)
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Lawrence Berkeley National Laboratory