Searching for up to 100 curated homologs for 5208351 Shew_0863 ABC transporter-related protein (RefSeq) (342 a.a.)
Found high-coverage hits (≥70%) to 57 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.10.4 / Q82VN5 Putative iron transport system ATP-binding protein, component of The Fe-hydroxamate-type siderophore uptake porter (transports Fe+3 bound to ferrioxamine, ferrichrome or pyoverdine siderophores) from Nitrosomonas europaea (see paper)
40% identity, 100% coverage of query (263 bits)
TC 3.A.1.10.2 / P74127 FutC aka SLL1878, component of Ferric iron (Fe3+) porter (see paper)
41% identity, 99% coverage of query (256 bits)
TC 3.A.1.11.6 / Q1M7Q1 Putative ABC transporter component, component of The γ-aminobutyrate (GABA) uptake system, GtsABCD from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
40% identity, 99% coverage of query (233 bits)
TC 3.A.1.20.1 / O54370 BitD, component of The iron transporter, BitABCDEF from Treponema hyodysenteriae (Serpulina hyodysenteriae) (see paper)
39% identity, 89% coverage of query (229 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
40% identity, 82% coverage of query (225 bits)
PotG / b0855 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PotG / P31134 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
POTG_ECOLI / P31134 Putrescine transport ATP-binding protein PotG; EC 7.6.2.16 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.11.2 / P31134 PotG aka B0855, component of Putrescine porter from Escherichia coli (see 4 papers)
40% identity, 89% coverage of query (220 bits)
TC 3.A.1.10.5 / A1JLH0 Iron(III)-transport ATP-binding protein, component of Siderophore-independent iron uptake system, AfuABC from Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081)
42% identity, 83% coverage of query (216 bits)
TC 3.A.1.10.3 / P44513 FbpC, component of Ferric iron (Fe3+) porter, FbpABC or HitABC (selective for trivalent cations, Fe3+, Ga3+ and Al3+) from Haemophilus influenzae (see 3 papers)
fbpC / OMNI|HI_0099 Fe(3+)-transporting ATPase; EC 3.6.3.30 from Haemophilus influenzae (see paper)
40% identity, 82% coverage of query (214 bits)
Q8YM92 ABC-type polyamine transporter (subunit 3/3) (EC 7.6.2.11) from Nostoc sp. PCC 7120 = FACHB-418 (see paper)
37% identity, 89% coverage of query (210 bits)
PHNT_SALTY / P96063 Putative 2-aminoethylphosphonate import ATP-binding protein PhnT from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.11.5 / P96063 PhnT aka STM0428, component of 2-aminoethyl phosphonate porter from Salmonella typhimurium (see 2 papers)
36% identity, 100% coverage of query (209 bits)
YagC / b0262 CP4-6 prophage; ABC transporter ATP-binding protein AfuC from Escherichia coli K-12 substr. MG1655 (see 4 papers)
41% identity, 71% coverage of query (209 bits)
TC 3.A.1.10.1 / P21410 SfuC aka FBPC, component of Ferric iron (Fe3+) porter, SfuABC (Angerer et al. 1990). These iron uptake systems have been reviewed (Angerer et al. 1992). Delepelaire 2019 reviewed structural and functional aspects of iron ABC transporters with emphasis on their substrate binding proteins from Serratia marcescens (see paper)
40% identity, 83% coverage of query (205 bits)
Pf1N1B4_5115 sucrose ABC transporter, ATPase component from Pseudomonas fluorescens FW300-N1B4
39% identity, 91% coverage of query (204 bits)
Dshi_0546 ABC transporter for Xylitol, ATPase component from Dinoroseobacter shibae DFL-12
39% identity, 87% coverage of query (204 bits)
yfuC / CAA87396.1 YfuC protein from Yersinia enterocolitica (see paper)
41% identity, 83% coverage of query (204 bits)
A0A142UTH4 ABC-type polyamine transporter (subunit 4/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
37% identity, 97% coverage of query (204 bits)
YdcT / b1441 putative ABC transporter ATP-binding protein YdcT from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ydcT / P77795 putative ABC transporter ATP-binding protein YdcT from Escherichia coli (strain K12) (see 3 papers)
YDCT_ECOLI / P77795 Uncharacterized ABC transporter ATP-binding protein YdcT from Escherichia coli (strain K12) (see paper)
37% identity, 92% coverage of query (203 bits)
TC 3.A.1.1.16 / Q8TZQ3 MalK aka PF1933, component of Maltooligosaccharide porter (Maltose is not a substrate, but maltotriose is.) from Pyrococcus furiosus
36% identity, 94% coverage of query (202 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
40% identity, 73% coverage of query (201 bits)
TC 3.A.1.20.2 / Q9KLQ5 Fe(3+) ions import ATP-binding protein FbpC, component of Hexose-phosphate transporter from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
33% identity, 99% coverage of query (200 bits)
SM_b20002 ABC transporter for Lactose, ATPase component from Sinorhizobium meliloti 1021
39% identity, 84% coverage of query (200 bits)
PS417_12700 ABC transporter for D-Mannitol and D-Sorbitol, ATPase component from Pseudomonas simiae WCS417
36% identity, 92% coverage of query (200 bits)
1g291 / Q9YGA6 Malk (see paper)
42% identity, 73% coverage of query (200 bits)
MALK_THELN / Q9YGA6 Trehalose/maltose import ATP-binding protein MalK; EC 7.5.2.1 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 5 papers)
42% identity, 73% coverage of query (199 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
39% identity, 78% coverage of query (196 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
40% identity, 73% coverage of query (195 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
39% identity, 78% coverage of query (194 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
39% identity, 78% coverage of query (194 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
39% identity, 78% coverage of query (194 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
39% identity, 78% coverage of query (194 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
39% identity, 78% coverage of query (194 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
39% identity, 77% coverage of query (193 bits)
3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
42% identity, 83% coverage of query (190 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
34% identity, 96% coverage of query (186 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
35% identity, 84% coverage of query (181 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
35% identity, 84% coverage of query (181 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
35% identity, 84% coverage of query (181 bits)
2awnC / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
39% identity, 74% coverage of query (179 bits)
8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
35% identity, 72% coverage of query (166 bits)
8hprD Lpqy-sugabc in state 4
35% identity, 72% coverage of query (166 bits)
8hprC Lpqy-sugabc in state 4
35% identity, 72% coverage of query (166 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
32% identity, 82% coverage of query (154 bits)
2awnA / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
32% identity, 78% coverage of query (132 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
31% identity, 70% coverage of query (120 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
30% identity, 70% coverage of query (119 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
30% identity, 70% coverage of query (119 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
30% identity, 70% coverage of query (119 bits)
7lkzA Structure of atp-bound human abca4
32% identity, 73% coverage of query (102 bits)
ABCAD_MOUSE / Q5SSE9 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Mus musculus (Mouse) (see 3 papers)
30% identity, 73% coverage of query (91.3 bits)
Build an alignment for 5208351 and 49 homologs with ≥ 30% identity
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DPPD_CALS4 / Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
28% identity, 73% coverage of query (87.8 bits)
4myhB Structure of the glutathione bound mitochondrial abc transporter, atm1
27% identity, 73% coverage of query (86.7 bits)
7pslA / P40416 S. Cerevisiae atm1 in msp1d1 nanodiscs in nucleotide-free state (see paper)
27% identity, 73% coverage of query (86.7 bits)
ATM1_YEAST / P40416 Iron-sulfur clusters transporter ATM1, mitochondrial; EC 7.-.-.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
TC 3.A.1.210.1 / P40416 The mitochondrial iron transporter, ATM1 from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
ATM1 / RF|NP_014030.1 iron-sulfur clusters transporter ATM1, mitochondrial from Saccharomyces cerevisiae
27% identity, 73% coverage of query (86.3 bits)
ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
28% identity, 70% coverage of query (84.7 bits)
ABCA6_HUMAN / Q8N139 ATP-binding cassette sub-family A member 6; EC 7.6.2.- from Homo sapiens (Human) (see 3 papers)
TC 3.A.1.211.15 / Q8N139 ATP-binding cassette sub-family A member 6, ABCA6 of 1617 aas. This transporter may play a role in macrophage lipid homeostasis. It is up-regulated during monocyte differentiation into macrophages but down-regulated by cholesterol loading of macrophages from Homo sapiens
25% identity, 77% coverage of query (80.1 bits)
STE6_YEAST / P12866 Alpha-factor-transporting ATPase; Mating factor A secretion protein STE6; Multiple drug resistance protein homolog; P-glycoprotein; EC 7.4.2.7 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P12866 ABC-type alpha-factor-pheromone transporter (EC 7.4.2.7) from Saccharomyces cerevisiae (see paper)
TC 3.A.1.206.1 / P12866 a-Factor sex pheromone (a hydrophobic isoprenylated (farnesylated) carboxymethylated peptide) exporter, Ste6 from Saccharomyces cerevisiae (Baker's yeast) (see 9 papers)
STE6 / RF|NP_012713.1 alpha-factor-transporting ATPase from Saccharomyces cerevisiae
30% identity, 70% coverage of query (80.1 bits)
ABCA9_HUMAN / Q8IUA7 ATP-binding cassette sub-family A member 9; EC 7.6.2.- from Homo sapiens (Human) (see paper)
TC 3.A.1.211.16 / Q8IUA7 ATP-binding cassette sub-family A member 9, ABCA9 of 1624 aas. May play a role in monocyte differentiation and lipid homeostasis. Expressed in fetal tissues with highest expression in fetal heart and kidney. Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages from Homo sapiens
26% identity, 70% coverage of query (76.3 bits)
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Lawrence Berkeley National Laboratory