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Searching for up to 100 curated homologs for 5208391 FitnessBrowser__PV4:5208391 (173 a.a.)

Found high-coverage hits (≥70%) to 31 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YhhY / b3441 N-acetyltransferase YhhY from Escherichia coli K-12 substr. MG1655 (see 4 papers)
AAAT_ECOLI / P46854 L-amino acid N-acetyltransferase AaaT; L-methionine N-acetyltransferase; L-phenylalanine N-acetyltransferase; EC 2.3.1.-; EC 2.3.1.53 from Escherichia coli (strain K12) (see 2 papers)
    47% identity, 92% coverage of query (151 bits)

Q9I3W7 amino-acid N-acetyltransferase (EC 2.3.1.1) from Pseudomonas aeruginosa (see paper)
    41% identity, 95% coverage of query (144 bits)

2vi7C / Q9I3W7 Structure of a putative acetyltransferase (pa1377)from pseudomonas aeruginosa (see paper)
    42% identity, 94% coverage of query (143 bits)

2ge3A / A9CI25 Crystal structure of probable acetyltransferase from agrobacterium tumefaciens
    32% identity, 80% coverage of query (73.9 bits)

Build an alignment

Build an alignment for 5208391 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

4jwpA / Q2YRK4 Crystal structure of ribosomal-protein-alanine n-acetyltransferase from brucella melitensis in complex with acetyl coa
    28% identity, 91% coverage of query (56.6 bits)

4pv6G / Q97CT7 Crystal structure analysis of ard1 from thermoplasma volcanium (see paper)
    31% identity, 92% coverage of query (50.8 bits)

4pv6A Crystal structure analysis of ard1 from thermoplasma volcanium
    31% identity, 92% coverage of query (50.8 bits)

ATDA_VIBCH / Q9KL03 Spermidine N(1)-acetyltransferase; SAT; Spermidine/spermine N(1)-acetyltransferase; SSAT; EC 2.3.1.57 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 3 papers)
Q9KL03 diamine N-acetyltransferase (EC 2.3.1.57) from Vibrio cholerae (see 2 papers)
    25% identity, 87% coverage of query (50.4 bits)

6e1xC / Q9KL03 Crystal structure of product-bound complex of spermidine/spermine n- acetyltransferase speg
    25% identity, 87% coverage of query (50.4 bits)

6e1xA Crystal structure of product-bound complex of spermidine/spermine n- acetyltransferase speg
    25% identity, 87% coverage of query (50.4 bits)

4r87A Crystal structure of spermidine n-acetyltransferase from vibrio cholerae in complex with coa and spermine
    25% identity, 87% coverage of query (50.4 bits)

4r57A Crystal structure of spermidine n-acetyltransferase from vibrio cholerae in complex with acetyl-coa
    25% identity, 87% coverage of query (50.4 bits)

4nczA Spermidine n-acetyltransferase from vibrio cholerae in complex with 2- [n-cyclohexylamino]ethane sulfonate.
    25% identity, 87% coverage of query (50.4 bits)

4mi4A Crystal structure of spermidine n-acetyltransferase from vibrio cholerae in complex with spermine
    25% identity, 87% coverage of query (50.4 bits)

4mhdA Crystal structure of spermidine n-acetyltransferase from vibrio cholerae in complex with spermidine
    25% identity, 87% coverage of query (50.4 bits)

5cnpB X-ray crystal structure of spermidine n1-acetyltransferase from vibrio cholerae.
    25% identity, 87% coverage of query (50.4 bits)

6cx8A Crystal structure of spermidine/spermine n-acetyltransferase speg from vibrio cholerae in complex with manganese ions.
    25% identity, 87% coverage of query (50.4 bits)

6vfnA Crystal structure of speg allosteric polyamine acetyltransferase from bacillus thuringiensis in complex with spermine (see paper)
    25% identity, 91% coverage of query (50.1 bits)

A0A0H2XGJ0 diamine N-acetyltransferase (EC 2.3.1.57) from Staphylococcus aureus (see paper)
    25% identity, 86% coverage of query (50.1 bits)

SpeG / b1584 spermidine N-acetyltransferase (EC 2.3.1.57) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
speG / P0A951 spermidine N-acetyltransferase (EC 2.3.1.57) from Escherichia coli (strain K12) (see 8 papers)
ATDA_ECOLI / P0A951 Spermidine N(1)-acetyltransferase; SAT; Spermidine/spermine N(1)-acetyltransferase; SSAT; EC 2.3.1.57 from Escherichia coli (strain K12) (see 10 papers)
P0A951 diamine N-acetyltransferase (EC 2.3.1.57) from Escherichia coli (see 3 papers)
    23% identity, 93% coverage of query (48.5 bits)

4jxrB / Q92L60 Crystal structure of a gnat superfamily phosphinothricin acetyltransferase (pat) from sinorhizobium meliloti in complex with accoa
    27% identity, 91% coverage of query (48.1 bits)

RIMI_MYCTU / I6YG32 N-alpha-acetyltransferase RimI; EC 2.3.1.255; EC 2.3.1.258 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
I6YG32 N-terminal amino-acid Nalpha-acetyltransferase NatA (EC 2.3.1.255); N-terminal methionine Nalpha-acetyltransferase NatC (EC 2.3.1.256); N-terminal methionine Nalpha-acetyltransferase NatE (EC 2.3.1.258) from Mycobacterium tuberculosis (see 2 papers)
    33% identity, 74% coverage of query (46.2 bits)

5dwnA / A0A0H3AQB6 Crystal structure of phosphinothricin n-acetyltransferase from brucella ovis in complex with acetylcoa
    29% identity, 89% coverage of query (45.8 bits)

4r9mA Crystal structure of spermidine n-acetyltransferase from escherichia coli
    23% identity, 93% coverage of query (45.1 bits)

A0A0M3KKU5 diamine N-acetyltransferase (EC 2.3.1.57) from Escherichia coli (see paper)
3wr7A / A0A0M3KKU5 Crystal structure of spermidine acetyltransferase from escherichia coli (see paper)
    23% identity, 90% coverage of query (44.7 bits)

5c88A / Q980R9 Crystal structure of ard1 n-terminal acetyltransferase from sulfolobus solfataricus in monoclinic form (see paper)
    29% identity, 92% coverage of query (43.9 bits)

4r3lA Crystal structure of ard1 n-terminal acetyltransferase from sulfolobus solfataricus bound to substrate peptide fragment and coa
    29% identity, 92% coverage of query (43.9 bits)

4r3kA Crystal structure of ard1 n-terminal acetyltransferase from sulfolobus solfataricus bound to coa
    29% identity, 92% coverage of query (43.9 bits)

4lx9A Archaeal amino-terminal acetyltransferase (nat) bound to acetyl coenzyme a
    29% identity, 92% coverage of query (43.9 bits)

NAT_SACS2 / Q980R9 N-alpha-acetyltransferase; NAT; Amino-terminal acetyltransferase; N-terminal acetyltransferase; EC 2.3.1.255; EC 2.3.1.258 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 4 papers)
Q980R9 N-terminal amino-acid Nalpha-acetyltransferase NatA (EC 2.3.1.255) from Saccharolobus solfataricus (see paper)
    29% identity, 92% coverage of query (43.9 bits)

6d72B / A0A5P8YIA2 Crystal structure of spermidine/spermine n-acetyltransferase speg from yersinia pestis in complex with calcium ions.
    24% identity, 75% coverage of query (43.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory