Sites on a Tree

 

Searching for up to 100 curated homologs for 5208646 FitnessBrowser__PV4:5208646 (335 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

LtaA / b0870 low-specificity L-threonine aldolase (EC 4.1.2.48; EC 4.1.2.5; EC 4.1.2.26; EC 4.1.2.49) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ltaE / P75823 low-specificity L-threonine aldolase (EC 4.1.2.48; EC 4.1.2.26) from Escherichia coli (strain K12) (see 4 papers)
LTAE_ECOLI / P75823 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Escherichia coli (strain K12) (see paper)
P75823 low-specificity L-threonine aldolase (EC 4.1.2.48) from Escherichia coli (see 2 papers)
itaE / GB|BAA20882.1 threonine aldolase; EC 4.1.2.5 from Escherichia coli K12 (see 4 papers)
    57% identity, 97% coverage of query (358 bits)

3wlxA Crystal structure of low-specificity l-threonine aldolase from escherichia coli
    57% identity, 97% coverage of query (358 bits)

4lnjA Structure of escherichia coli threonine aldolase in unliganded form (see paper)
    57% identity, 95% coverage of query (357 bits)

4rjyA Crystal structure of e. Coli l-threonine aldolase in complex with a non-covalently uncleaved bound l-serine substrate
    57% identity, 95% coverage of query (357 bits)

4lnmA Structure of escherichia coli threonine aldolase in complex with serine
    57% identity, 95% coverage of query (357 bits)

4lnlA Structure of escherichia coli threonine aldolase in complex with allo- thr
    57% identity, 95% coverage of query (357 bits)

ltaA / O07051 L-allo-threonine aldolase subunit (EC 4.1.2.48) from Aeromonas jandaei (see paper)
LTAA_AERJA / O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see 2 papers)
O07051 L-allo-threonine aldolase (EC 4.1.2.49) from Aeromonas jandaei (see 4 papers)
ltaA / GB|BAA20404.1 L-allo-threonine aldolase; EC 4.1.2.- from Aeromonas jandaei (see 2 papers)
    55% identity, 100% coverage of query (345 bits)

3wgcB / O07051 Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
    55% identity, 100% coverage of query (338 bits)

3wgbD Crystal structure of aeromonas jandaei l-allo-threonine aldolase
    54% identity, 100% coverage of query (325 bits)

Q9X266 L-threonine aldolase (EC 4.1.2.5) from Thermotoga maritima (see paper)
    45% identity, 100% coverage of query (296 bits)

1jg8D / Q9X266 Crystal structure of threonine aldolase (low-specificity)
    45% identity, 100% coverage of query (296 bits)

1lw5B X-ray structure of l-threonine aldolase (low-specificity) in complex with glycine
    45% identity, 100% coverage of query (296 bits)

1lw4B X-ray structure of l-threonine aldolase (low-specificity) in complex with l-allo-threonine
    45% identity, 100% coverage of query (296 bits)

THA2_ARATH / Q9FPH3 Probable low-specificity L-threonine aldolase 2; Threonine aldolase 2; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    42% identity, 100% coverage of query (275 bits)

THA1_ARATH / Q8RXU4 Low-specificity L-threonine aldolase 1; Threonine aldolase 1; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    42% identity, 96% coverage of query (259 bits)

GLY1 / P37303 L-threonine aldolase subunit (EC 4.1.2.48) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
GLY1_YEAST / P37303 Low specificity L-threonine aldolase; Low specificity L-TA; TA; EC 4.1.2.48 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P37303 low-specificity L-threonine aldolase (EC 4.1.2.48) from Saccharomyces cerevisiae (see paper)
    41% identity, 77% coverage of query (184 bits)

GLY1 / GB|AAA72430.1 threonine aldolase; EC 4.1.2.5 from Saccharomyces cerevisiae (see paper)
    41% identity, 77% coverage of query (184 bits)

orf19.6305 hydroxytrimethyllysine aldolase from Candida albicans (see paper)
    38% identity, 84% coverage of query (178 bits)

GLY1 L-threonine aldolase from Candida albicans (see paper)
    38% identity, 77% coverage of query (178 bits)

O13427 low-specificity L-threonine aldolase (EC 4.1.2.48) from Candida albicans (see paper)
    38% identity, 77% coverage of query (176 bits)

GLY1 / CAA06545.1 threonine aldolase from Eremothecium gossypii (see paper)
    37% identity, 78% coverage of query (173 bits)

TOXG_COCCA / Q9UW18 Alanine racemase TOXG; TOX2 HC-toxin biosynthesis cluster protein TOXG; EC 5.1.1.1 from Cochliobolus carbonum (Maize leaf spot fungus) (Bipolaris zeicola) (see 2 papers)
    31% identity, 99% coverage of query (133 bits)

Build an alignment

Build an alignment for 5208646 and 22 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

No additional hits (below 30% identity) were found

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory