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Searching for up to 100 curated homologs for 5209405 FitnessBrowser__PV4:5209405 (707 a.a.)

Found high-coverage hits (≥70%) to 13 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5hq4A / A0A0Y0DFX2 A glycoside hydrolase family 97 enzyme from pseudoalteromonas sp. Strain k8 (see paper)
    66% identity, 93% coverage of query (921 bits)

5hqaA A glycoside hydrolase family 97 enzyme in complex with acarbose from pseudoalteromonas sp. Strain k8
    66% identity, 93% coverage of query (921 bits)

AEW20125.1 α-glucosidase (SusB;Aglu;BFO_2272) (EC 3.2.1.20) (see protein)
    41% identity, 92% coverage of query (509 bits)

2jkpA Structure of a family 97 alpha-glucosidase from bacteroides thetaiotaomicron in complex with castanospermine
    39% identity, 93% coverage of query (478 bits)

2jkeA Structure of a family 97 alpha-glucosidase from bacteroides thetaiotaomicron in complex with deoxynojirimycin
    39% identity, 93% coverage of query (478 bits)

3wfaA Catalytic role of the calcium ion in gh97 inverting glycoside hydrolase
    39% identity, 93% coverage of query (477 bits)

2zq0A Crystal structure of susb complexed with acarbose
    38% identity, 93% coverage of query (476 bits)

SUSB_BACTN / G8JZS4 Glucan 1,4-alpha-glucosidase SusB; Alpha-glucosidase SusB; Glucoamylase SusB; Starch-utilization system protein B; EC 3.2.1.3 from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) (see 2 papers)
AAC44671.1 α-glucosidase / glucoamylase (SusB;BtGH97a;BT3703;BT_3703) (EC 3.2.1.3) (see protein)
    38% identity, 93% coverage of query (474 bits)

2d73A / G8JZS4 Crystal structure analysis of susb (see paper)
    38% identity, 93% coverage of query (474 bits)

Build an alignment

Build an alignment for 5209405 and 9 homologs with ≥ 30% identity

Select sequences

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Additional hits (identity < 30%)

AGAL_BACTN / Q8A6L0 Retaining alpha-galactosidase; BtGH97b; Melibiase; EC 3.2.1.22 from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) (see 2 papers)
AAO76978.1 α-galactosidase (BtGH97b;BT1871;BT_1871) (EC 3.2.1.22) (see protein)
    26% identity, 96% coverage of query (229 bits)

5e1qB / Q8A6L0 Mutant (d415g) gh97 alpha-galactosidase in complex with gal-lac (see paper)
    26% identity, 92% coverage of query (228 bits)

AAO77727.1 α-mannan α-galactosidase (BT2620) (EC 3.2.1.22) (see protein)
    25% identity, 92% coverage of query (167 bits)

5xfmA / Q8A1K0 Crystal structure of beta-arabinopyranosidase (see paper)
    23% identity, 92% coverage of query (121 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory