Searching for up to 100 curated homologs for 5209856 FitnessBrowser__PV4:5209856 (376 a.a.)

Found high-coverage hits (≥70%) to 26 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5dt9A / Q9KQ92 Crystal structure of a putative d-erythronate-4-phosphate dehydrogenase from vibrio cholerae
    50% identity, 99% coverage of query (348 bits)

3oetH / P60802 D-erythronate-4-phosphate dehydrogenase complexed with NAD
    46% identity, 99% coverage of query (306 bits)

PdxB / b2320 erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
pdxB / P05459 erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) from Escherichia coli (strain K12) (see 20 papers)
PDXB_ECOLI / P05459 Erythronate-4-phosphate dehydrogenase; EC 1.1.1.290 from Escherichia coli (strain K12) (see 2 papers)
P05459 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) from Escherichia coli (see 3 papers)
    48% identity, 99% coverage of query (297 bits)

PDXB_PSEAE / Q9I3W9 Erythronate-4-phosphate dehydrogenase; EC 1.1.1.290 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
Q9I3W9 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) from Pseudomonas aeruginosa (see paper)
2o4cA / Q9I3W9 Crystal structure of d-erythronate-4-phosphate dehydrogenase complexed with NAD (see paper)
    47% identity, 95% coverage of query (289 bits)

Q7N2B2 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) from Photorhabdus luminescens (see paper)
    45% identity, 99% coverage of query (277 bits)

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Build an alignment for 5209856 and 5 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

O58256 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pyrococcus horikoshii (see paper)
    28% identity, 73% coverage of query (114 bits)

P9WNX3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Mycobacterium tuberculosis (see 5 papers)
    31% identity, 70% coverage of query (112 bits)

3ddnB Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis
    31% identity, 70% coverage of query (112 bits)

3dc2A / P9WNX3 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis (see paper)
    31% identity, 70% coverage of query (111 bits)

PHGDH / O43175 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) from Homo sapiens (see 3 papers)
SERA_HUMAN / O43175 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) (see 7 papers)
O43175 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Homo sapiens (see 8 papers)
    26% identity, 70% coverage of query (106 bits)

Phgdh / O08651 3-phosphoglycerate dehydrogenase subunit (EC 1.1.1.95) from Rattus norvegicus (see paper)
SERA_RAT / O08651 D-3-phosphoglycerate dehydrogenase; 3-PGDH; EC 1.1.1.95 from Rattus norvegicus (Rat) (see paper)
O08651 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Rattus norvegicus (see paper)
    26% identity, 70% coverage of query (105 bits)

SERA_MOUSE / Q61753 D-3-phosphoglycerate dehydrogenase; 3-PGDH; A10; EC 1.1.1.95 from Mus musculus (Mouse) (see paper)
Q61753 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Mus musculus (see 2 papers)
    26% identity, 70% coverage of query (105 bits)

7dkmA / O43175 Phgdh covalently linked to oridonin (see paper)
    26% identity, 70% coverage of query (105 bits)

6cwaA Crystal structure phgdh in complex with nadh and 3-phosphoglycerate at 1.77 a resolution
    26% identity, 70% coverage of query (105 bits)

6rj3A Crystal structure of phgdh in complex with compound 15
    26% identity, 70% coverage of query (105 bits)

6rj5A Crystal structure of phgdh in complex with compound 39
    26% identity, 70% coverage of query (105 bits)

7ewhA Crystal structure of human phgdh in complex with homoharringtonine
    26% identity, 70% coverage of query (105 bits)

6rihA Crystal structure of phgdh in complex with compound 9
    26% identity, 70% coverage of query (105 bits)

6plgA Crystal structure of human phgdh complexed with compound 15
    26% identity, 70% coverage of query (105 bits)

6plfA Crystal structure of human phgdh complexed with compound 1
    26% identity, 70% coverage of query (105 bits)

6rj2A Crystal structure of phgdh in complex with compound 40
    26% identity, 70% coverage of query (105 bits)

SERA2_ARATH / O04130 D-3-phosphoglycerate dehydrogenase 2, chloroplastic; PGDH; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O04130 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 3 papers)
    27% identity, 74% coverage of query (101 bits)

A0A2R6X868 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Marchantia polymorpha (see paper)
    27% identity, 72% coverage of query (100 bits)

6plfB Crystal structure of human phgdh complexed with compound 1
    26% identity, 70% coverage of query (98.6 bits)

SERA3_ARATH / Q9LT69 D-3-phosphoglycerate dehydrogenase 3, chloroplastic; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LT69 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 4 papers)
    27% identity, 74% coverage of query (95.1 bits)

CTBP2_HUMAN / P56545 C-terminal-binding protein 2; CtBP2 from Homo sapiens (Human) (see 5 papers)
    23% identity, 79% coverage of query (74.7 bits)

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