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Searching for up to 100 curated homologs for 5210055 FitnessBrowser__PV4:5210055 (261 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SapF / b1290 putrescine ABC exporter ATP binding protein SapF (EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
SapF / P0AAH8 putrescine ABC exporter ATP binding protein SapF (EC 7.6.2.16) from Escherichia coli (strain K12) (see 2 papers)
SAPF_ECOLI / P0AAH8 Putrescine export system ATP-binding protein SapF from Escherichia coli (strain K12) (see 2 papers)
sapF / MB|P0AAH8 peptide transport system ATP-binding protein sapF from Escherichia coli K12 (see 4 papers)
    51% identity, 96% coverage of query (275 bits)

SAPF_SALTY / P36638 Peptide transport system ATP-binding protein SapF from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.5.5 / P36638 SapF aka STM1696, component of Probable cationic peptide porter (may also take up peptide antibiotics and protamine; implicated in K+ homeostasis) [SapD can stimulate the K+ uptake activities of TrkH and TrkG (TC #2.A.38.1.1) in the presence of ATP] from Salmonella typhimurium (see 2 papers)
    51% identity, 96% coverage of query (272 bits)

DppF / b3540 dipeptide ABC transporter ATP binding subunit DppF (EC 7.4.2.9) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
DppF / P37313 dipeptide ABC transporter ATP binding subunit DppF (EC 7.4.2.9) from Escherichia coli (strain K12) (see 2 papers)
DPPF_ECOLI / P37313 Dipeptide transport ATP-binding protein DppF; EC 7.4.2.9 from Escherichia coli (strain K12) (see 3 papers)
    47% identity, 96% coverage of query (246 bits)

TC 3.A.1.5.44 / O86191 SapF protein, component of Peptide transporter, SapABCDF. Mutants are more sensitive than the wild type to wheat alpha-thionin and to snakin-1, which is the most abundant antimicrobial peptide from potato tubers. They were also less virulent than was the wild-type strain in potato tubers: lesion areas were 37% that of the control, and the growth rate was two orders of magnitude lower. Thus, the interaction of antimicrobial peptides from the host with the sapA-F operon from the pathogen plays a similar role in animal and in plant bacterial pathogenesis from Dickeya chrysanthemi
    47% identity, 96% coverage of query (243 bits)

TC 3.A.1.5.27 / P45094 Dipeptide transport ATP-binding protein DppF, component of The glutathione uptake porter, DppBCDF with the glutathione binding protein, DppA (GbpA; HbpA). Takes up reduced (GSH) and oxidized (GSSG) but not bulky glutathione S conjugates or glutathione derivatives with C-terminal modifications from Haemophilus influenzae (see 2 papers)
    45% identity, 98% coverage of query (241 bits)

TC 3.A.1.5.37 / B1W1L8 Putative peptide ABC transporter ATP-binding protein, component of The ABC BldKA-E (SGR_2418-2414) oligopeptide transport system. It controls aerial mycelium formation on glucose media. Probably involved in extracellular peptide signalling (Akanuma et al. 2011).  Probably orthologous to 3.A.1.5.35 from Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
    46% identity, 95% coverage of query (226 bits)

TC 3.A.1.5.39 / W0WLZ8 Dipeptide transport ATP-binding protein DppF, component of Di- and tri-peptide transporter, DppBCDF with periplasmic substrate binding receptors, A1, A3, A5, A7 and A9, each with differing specificities for peptides from Pseudomonas aeruginosa MH38
    43% identity, 92% coverage of query (222 bits)

DPPF_PSEAB / A0A0H2ZH52 Di/tripeptide transport ATP-binding protein DppF; EC 7.4.2.9 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
    43% identity, 92% coverage of query (222 bits)

GsiA / b0829 glutathione ABC transporter ATP binding subunit GsiA (EC 7.4.2.10) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
gsiA / P75796 glutathione ABC transporter ATP binding subunit GsiA (EC 7.4.2.10) from Escherichia coli (strain K12) (see 3 papers)
GSIA_ECOLI / P75796 Glutathione import ATP-binding protein GsiA; EC 7.4.2.10 from Escherichia coli (strain K12) (see paper)
P75796 ABC-type glutathione transporter (EC 7.4.2.10) from Escherichia coli (see paper)
TC 3.A.1.5.11 / P75796 Hypothetical ABC transporter ATP-binding protein yliA, component of Glutathione porter, YliABCD or GsiABCD from Escherichia coli (see 4 papers)
    45% identity, 95% coverage of query (220 bits)

Q8ZQM4 ABC-type glutathione transporter (EC 7.4.2.10) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    47% identity, 95% coverage of query (219 bits)

TC 3.A.1.5.12 / Q9X0F3 TM1063, component of Probable rhamnose oligosaccharide porter. Induced by rhamnose (see paper)
    42% identity, 95% coverage of query (216 bits)

TC 3.A.1.5.36 / Q8CJS2 Putative peptide transport system ATP-binding subunit, component of Peptide transporter encoded adjacent to the putative transport system with TC#3.A.1.5.35 (Akanuma et al. 2011). Induced by exogenous S-adenosylmethionine (SAM) at a concentration of 2muM which also enhanced antibiotic production and inhibited morphological development (Park et al. 2005). SAM can be imported into cells. Mutants in the bldK genes confer resistance to the toxic tripeptide, bialaphos from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    43% identity, 95% coverage of query (214 bits)

TC 3.A.1.5.29 / Q9WXR3 Oligopeptide ABC transporter, ATP-binding protein, component of Probable xylan oligosaccharide porter (Conners et al. 2005). Induced by cylan and xylose. Regulated by xylose-responsive regulator XylR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    41% identity, 95% coverage of query (213 bits)

Q5V9R8 ABC-type oligopeptide transporter (EC 7.4.2.6) from Vibrio fluvialis (see paper)
TC 3.A.1.5.22 / Q5V9R8 OppF, component of The peptide transporter OppA,B,C,D,F (influences biofilm formation; Lee et al., 2004). Similar to 3.A.1.5.1, OppA is similar to the Vibrio furnissii OppA that provides several functions: hemolysis, antibiotic resistance, and virulence from Vibrio fluvialis (see paper)
    43% identity, 90% coverage of query (213 bits)

TC 3.A.1.5.19 / Q2FZR4 OppF, component of The major oligopeptide uptake porter, Opp-3 (of four paralogues, this is the only one that mediates nitrogen nutrition from Staphylococcus aureus (strain NCTC 8325)
    43% identity, 95% coverage of query (211 bits)

OPPF_BACSU / P24137 Oligopeptide transport ATP-binding protein OppF; Stage 0 sporulation protein KE from Bacillus subtilis (strain 168) (see paper)
    41% identity, 96% coverage of query (207 bits)

TC 3.A.1.5.1 / P08007 OppF aka STM1742, component of Oligopeptide porter (also takes up amino glycoside antibiotics such as kanamycin, streptomycin and neomycin as well as cell wall-derived peptides such as murein tripeptide). It transports substrate peptides of 2-5 amino acids with highest affinity for tripeptides. Also transports δ-aminolevulinic acid (ALA). [May be regulated by PTS Enzyme INtr-aspartokinase.] ATP-binding to OppDF may result in donation of peptide to OppBC and simultaneous release of OppA from Salmonella typhimurium (see 2 papers)
    44% identity, 85% coverage of query (206 bits)

OppF / b1247 murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppF (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
oppF / P77737 murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppF (EC 7.4.2.6) from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.5.41 / P77737 Oligopeptide transport ATP-binding protein OppF, component of Oligopeptide transporter, OppABCDF/MppA/YgiS from Escherichia coli (strain K12)
    43% identity, 85% coverage of query (205 bits)

TC 3.A.1.5.20 / P42065 AppF, component of 5-6 amino acyl oligopeptide transporter AppA-F from Bacillus subtilis (see 3 papers)
    42% identity, 92% coverage of query (204 bits)

DdpF / b1483 putative D,D-dipeptide ABC transporter ATP-binding subunit DdpF from Escherichia coli K-12 substr. MG1655 (see 2 papers)
DDPF_ECOLI / P77622 Probable D,D-dipeptide transport ATP-binding protein DdpF from Escherichia coli (strain K12) (see paper)
    41% identity, 96% coverage of query (202 bits)

TC 3.A.1.5.10 / P0A2V4 OppF, component of Oligopeptide porter (transports peptides of 4-35) amino acyl residues; di- and tripeptides are not transported; hydrophobic basic peptides are preferred). OppA determines the specificity of the system (Doeven et al., 2004). A large cavity in OppA binds proline-rich peptides preferentially (Berntsson et al., 2009). Two crystal structures of OppA with different nonapeptides show binding in different registers from Lactococcus lactis subsp. lactis (Streptococcus lactis) (see 2 papers)
    39% identity, 85% coverage of query (201 bits)

TC 3.A.1.5.15 / Q9X272 TM1750, component of Probable mannose/mannoside porter. Induced by beta-mannan (Conners et al., 2005). Regulated by mannose-responsive regulator manR (see paper)
    41% identity, 95% coverage of query (199 bits)

DPPF_LACLM / A2RI78 Dipeptide transport ATP-binding protein DppF; EC 7.4.2.9 from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    39% identity, 95% coverage of query (192 bits)

TC 3.A.1.5.24 / Q8ZNJ8 YejF, component of The antimicrobial peptide (protamine, melittin, polymyxin B, human defensin (HBD)-1 and HBD-2 exporter, YejABEF (Eswarappa et al., 2008). Prefers N-formyl methionine peptides, such as Microcin C (of prokaryotic origin) to non formylated peptides (of eukaryotic origin) from Salmonella typhimurium (see paper)
    42% identity, 96% coverage of query (191 bits)

TC 3.A.1.5.25 / Q9CIK8 Oligopeptide ABC trasporter ATP binding protein, component of The ABC peptide/signalling peptide transporter. OptA binds peptides of 3-6 aas; OptS binds dipeptides. OptB,C,D are most similar to 3.A.1.5.19 from Lactococcus lactis subsp. lactis (see paper)
    39% identity, 95% coverage of query (191 bits)

TC 3.A.1.5.32 / F0TFS9 Oligopeptide ABC transporter ATP-binding protein, component of ABC α-galactoside uptake porter from Lactobacillus acidophilus (strain 30SC)
    36% identity, 92% coverage of query (189 bits)

YejF / b2180 putative oligopeptide ABC transporter ATP binding subunit YejF (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
YejF / P33916 putative oligopeptide ABC transporter ATP binding subunit YejF (EC 7.4.2.6) from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.5.21 / P33916 YejF, component of The Microcin C/peptide uptake porter, YejABEF from Escherichia coli (strain K12) (see 3 papers)
yejF / RF|NP_416685 uncharacterized ABC transporter ATP-binding protein yejF from Escherichia coli K12 (see paper)
    41% identity, 95% coverage of query (187 bits)

TC 3.A.1.5.23 / Q9F9T4 EppD, component of The Ethylene diamine tetraacetate (EDTA) uptake porter, EppABCD (see 2 papers)
    37% identity, 96% coverage of query (184 bits)

TC 3.A.1.5.26 / P63395 Uncharacterized ABC transporter ATP-binding protein Rv1281c/MT1318, component of The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis from Mycobacterium tuberculosis (see 2 papers)
    43% identity, 95% coverage of query (183 bits)

Q73NS6 ABC-type dipeptide transporter (EC 7.4.2.9) from Treponema denticola (see paper)
    34% identity, 92% coverage of query (182 bits)

SM_b21644 ABC transporter for D-Raffinose, ATPase component from Sinorhizobium meliloti 1021
    38% identity, 96% coverage of query (181 bits)

TC 3.A.1.5.8 / Q97UG5 MalK, component of Maltose and maltooligosaccharide porter from Sulfolobus solfataricus (see paper)
    37% identity, 95% coverage of query (181 bits)

MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
    35% identity, 95% coverage of query (139 bits)

3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
    35% identity, 95% coverage of query (138 bits)

3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
    35% identity, 95% coverage of query (138 bits)

6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
    35% identity, 95% coverage of query (138 bits)

7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp
    33% identity, 95% coverage of query (135 bits)

7z15I / P16678 E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
    33% identity, 95% coverage of query (135 bits)

7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation
    33% identity, 95% coverage of query (134 bits)

4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
    33% identity, 95% coverage of query (128 bits)

SapD / b1291 putrescine ABC exporter ATP binding protein SapD (EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
SapD / P0AAH4 putrescine ABC exporter ATP binding protein SapD (EC 7.6.2.16) from Escherichia coli (strain K12) (see 5 papers)
SAPD_ECOLI / P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see 2 papers)
    31% identity, 95% coverage of query (126 bits)

4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
    33% identity, 90% coverage of query (124 bits)

7ahhC Opua inhibited inward-facing, sbd docked
    34% identity, 84% coverage of query (121 bits)

7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
    34% identity, 84% coverage of query (121 bits)

3c4jA Abc protein artp in complex with atp-gamma-s
    33% identity, 86% coverage of query (121 bits)

3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
    33% identity, 86% coverage of query (121 bits)

2olkA Abc protein artp in complex with adp-beta-s
    33% identity, 86% coverage of query (121 bits)

2oljA Abc protein artp in complex with adp/mg2+
    33% identity, 86% coverage of query (121 bits)

7ahdC Opua (e190q) occluded
    34% identity, 82% coverage of query (118 bits)

Build an alignment

Build an alignment for 5210055 and 49 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
    29% identity, 98% coverage of query (117 bits)

ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
    30% identity, 85% coverage of query (111 bits)

4fwiB / Q8RDH4 Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
    33% identity, 85% coverage of query (108 bits)

DPPD_CALS4 / Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
    33% identity, 85% coverage of query (108 bits)

1f3oA / Q58206 Crystal structure of mj0796 atp-binding cassette (see paper)
    32% identity, 86% coverage of query (107 bits)

1l2tA Dimeric structure of mj0796, a bacterial abc transporter cassette
    32% identity, 86% coverage of query (106 bits)

1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    30% identity, 90% coverage of query (105 bits)

1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    30% identity, 90% coverage of query (105 bits)

GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
    30% identity, 90% coverage of query (105 bits)

3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
    33% identity, 97% coverage of query (103 bits)

8hprC Lpqy-sugabc in state 4
    29% identity, 87% coverage of query (103 bits)

8hprD Lpqy-sugabc in state 4
    29% identity, 87% coverage of query (103 bits)

8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
    29% identity, 87% coverage of query (102 bits)

2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
    29% identity, 87% coverage of query (102 bits)

sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
    29% identity, 87% coverage of query (101 bits)

5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
    29% identity, 85% coverage of query (100 bits)

8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
    29% identity, 85% coverage of query (100 bits)

8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
    28% identity, 88% coverage of query (99.0 bits)

P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
    30% identity, 86% coverage of query (99.0 bits)

Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
    31% identity, 84% coverage of query (99.0 bits)

1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
    29% identity, 87% coverage of query (98.2 bits)

4hluA / Q9WY65 Structure of the ecfa-a' heterodimer bound to adp (see paper)
    32% identity, 79% coverage of query (97.8 bits)

8g4cB / O34697 Bceabs atpgs high res tm (see paper)
    32% identity, 86% coverage of query (97.8 bits)

3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
    31% identity, 86% coverage of query (96.7 bits)

3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
    31% identity, 86% coverage of query (96.7 bits)

3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
    31% identity, 86% coverage of query (96.7 bits)

3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
    31% identity, 86% coverage of query (96.7 bits)

MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
    31% identity, 86% coverage of query (96.7 bits)

1q12A Crystal structure of the atp-bound e. Coli malk
    31% identity, 86% coverage of query (96.7 bits)

7tchB Bceab e169q variant atp-bound conformation
    31% identity, 86% coverage of query (96.7 bits)

2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    31% identity, 86% coverage of query (96.7 bits)

MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    30% identity, 86% coverage of query (96.7 bits)

6hrcB Outward-facing pglk with atpgammas bound
    31% identity, 87% coverage of query (95.9 bits)

6hrcA / O86150 Outward-facing pglk with atpgammas bound (see paper)
    31% identity, 87% coverage of query (95.9 bits)

5nbdA Pglk flippase in complex with inhibitory nanobody
    31% identity, 87% coverage of query (95.9 bits)

4zirA Crystal structure of ecfaa' heterodimer bound to amppnp
    33% identity, 79% coverage of query (95.9 bits)

LolD / b1117 lipoprotein release complex - ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 2 papers)
LolD / P75957 lipoprotein release complex - ATP binding subunit from Escherichia coli (strain K12) (see paper)
LOLD_ECOLI / P75957 Lipoprotein-releasing system ATP-binding protein LolD; EC 7.6.2.- from Escherichia coli (strain K12) (see paper)
TC 3.A.1.125.1 / P75957 LolD aka B1117, component of Lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope) (see 1.B.46; Narita et al., 2003; Ito et al., 2006; Watanabe et al., 2007). The structure of ligand-bound LolCDE has been solved (Ito et al., 2006). LolC and LolE each have 4 TMSs (1+3). Unlike most ATP binding cassette transporters mediating the transmembrane flux of substrates, the LolCDE complex catalyzes the extrusion of lipoproteins anchored to the outer leaflet of the inner membrane. The LolCDE complex is unusual in that it can be purified as a liganded form, which is an intermediate of the lipoprotein release reaction (Taniguchi and Tokuda, 2008). LolCDE has been reconstituted from separated subunits from Escherichia coli (see 5 papers)
lolD / GB|BAA35937.2 lipoprotein releasing system, ATP-binding protein; EC 3.6.3.- from Escherichia coli K12 (see 5 papers)
    32% identity, 85% coverage of query (95.9 bits)

pglK / Q0P9C4 ABC-type undecaprenyldiphosphate-linked heptasaccharide transporter monomer from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see 2 papers)
PGLK_CAMJE / Q0P9C4 Protein glycosylation K; EC 7.5.2.5 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see 3 papers)
TC 3.A.1.106.15 / Q0P9C4 Lipid flippase, PglK or WlaB, of 564 aas and 6 N-terminal TMSs with a C-terminal ATPase domain from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
    31% identity, 87% coverage of query (95.5 bits)

7mdyC Lolcde nucleotide-bound
    32% identity, 83% coverage of query (95.1 bits)

7arlD Lolcde in complex with lipoprotein and adp
    32% identity, 83% coverage of query (95.1 bits)

1g291 / Q9YGA6 Malk (see paper)
    28% identity, 87% coverage of query (94.7 bits)

7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
    31% identity, 83% coverage of query (94.4 bits)

7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
    31% identity, 83% coverage of query (94.4 bits)

2pmkA Crystal structures of an isolated abc-atpase in complex with tnp-adp
    30% identity, 84% coverage of query (94.4 bits)

2ff7A The abc-atpase of the abc-transporter hlyb in the adp bound state
    30% identity, 84% coverage of query (94.4 bits)

5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
    27% identity, 91% coverage of query (94.4 bits)

6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
    31% identity, 83% coverage of query (94.0 bits)

7v8iD / P75957 Lolcd(e171q)e with bound amppnp in nanodiscs (see paper)
    31% identity, 83% coverage of query (94.0 bits)

7t55A / A3DCU1 Cryo-em structure of pcat1 in the inward-facing wide conformation under atp turnover condition (see paper)
    32% identity, 80% coverage of query (93.6 bits)

5xu1B / Q8DQF8 Structure of a non-canonical abc transporter from streptococcus pneumoniae r6 (see paper)
    35% identity, 81% coverage of query (93.6 bits)

3b5jA Crystal structures of the s504a mutant of an isolated abc-atpase in complex with tnp-adp
    30% identity, 84% coverage of query (93.6 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory