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Searching for up to 100 curated homologs for 5210610 FitnessBrowser__PV4:5210610 (590 a.a.)

Found high-coverage hits (≥70%) to 38 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

asnO / Q92W82 N-acetylglutaminylglutamine amide synthase from Rhizobium meliloti (strain 1021) (see paper)
    53% identity, 99% coverage of query (609 bits)

ddaH / E2JA33 N-3-fumaroyl-(S)-2,3-diaminopropanoate aminotransferase from Enterobacter agglomerans (see 2 papers)
    33% identity, 100% coverage of query (298 bits)

asnB / GB|CAB15032.1 asparagine synthase (glutamine-hydrolysing) 1; EC 6.3.5.4 from Bacillus subtilis (see 4 papers)
    31% identity, 99% coverage of query (279 bits)

oxyD / L8EVF2 malonamoyl-CoA synthetase from Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234) (see 3 papers)
    33% identity, 88% coverage of query (264 bits)

asnO / GI|1934835 asparagine synthase (glutamine-hydrolysing) 3; EC 6.3.5.4 from Bacillus subtilis (see 3 papers)
    32% identity, 88% coverage of query (256 bits)

Build an alignment

Build an alignment for 5210610 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

asnH / Q9CDJ2 peptidoglycan asparagine synthase from Lactococcus lactis subsp. lactis (strain IL1403) (see paper)
    28% identity, 99% coverage of query (251 bits)

ltsA / BAD83576.1 glutamine amidotransferase from Rhodococcus erythropolis (see paper)
    32% identity, 96% coverage of query (250 bits)

ASNH_MYCBO / P64248 Putative asparagine synthetase [glutamine-hydrolyzing]; EC 6.3.5.4 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
    30% identity, 95% coverage of query (227 bits)

CHRY2_GIBZE / I1S3K8 Amidase chry2; Chrysogine biosynthesis cluster protein 2; EC 3.-.-.- from Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) (see paper)
    26% identity, 96% coverage of query (188 bits)

CHYD_PENRW / B6HLP8 Amidase chyE; Chrysogine biosynthesis cluster protein D; EC 3.-.-.- from Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum) (see paper)
    26% identity, 94% coverage of query (182 bits)

1ct9A / P22106 Crystal structure of asparagine synthetase b from escherichia coli (see paper)
    30% identity, 83% coverage of query (172 bits)

ASNS_SCHPO / P78753 Probable asparagine synthetase [glutamine-hydrolyzing]; Glutamine-dependent asparagine synthetase; EC 6.3.5.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
asn1 / RF|NP_595291.1 asparagine synthetase; EC 6.3.5.4 from Schizosaccharomyces pombe (see 2 papers)
    28% identity, 85% coverage of query (155 bits)

Q14SM9 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Glycine max (see paper)
    27% identity, 83% coverage of query (148 bits)

B3KYI2 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Phaseolus vulgaris (see paper)
    27% identity, 88% coverage of query (145 bits)

F2CQ60 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare subsp. vulgare (see paper)
    27% identity, 88% coverage of query (143 bits)

ASNS2_ORYSJ / Q43011 Asparagine synthetase [glutamine-hydrolyzing] 2; Glutamine-dependent asparagine synthetase 2; EC 6.3.5.4 from Oryza sativa subsp. japonica (Rice) (see paper)
Q43011 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Oryza sativa Japonica Group (see paper)
    27% identity, 88% coverage of query (142 bits)

F2DJ31 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare (see paper)
    27% identity, 88% coverage of query (142 bits)

D9IXC8 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Pinus pinaster (see paper)
    27% identity, 89% coverage of query (142 bits)

ASNS_MOUSE / Q61024 Asparagine synthetase [glutamine-hydrolyzing]; Glutamine-dependent asparagine synthetase; EC 6.3.5.4 from Mus musculus (Mouse) (see paper)
    27% identity, 88% coverage of query (140 bits)

Q6HA26 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Pinus sylvestris (see paper)
    27% identity, 88% coverage of query (140 bits)

Q9SP19 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Helianthus annuus (see paper)
    27% identity, 92% coverage of query (140 bits)

A0A1D5YL35 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Triticum aestivum (see paper)
    27% identity, 83% coverage of query (140 bits)

ASNS1_ARATH / P49078 Asparagine synthetase [glutamine-hydrolyzing] 1; Glutamine-dependent asparagine synthetase 1; Protein DARK INDUCIBLE 6; EC 6.3.5.4 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    27% identity, 89% coverage of query (139 bits)

Q93XP9 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare subsp. vulgare (see paper)
    27% identity, 83% coverage of query (138 bits)

E7EAQ2 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Pinus pinaster (see paper)
    27% identity, 89% coverage of query (138 bits)

ASNS2_YEAST / P49090 Asparagine synthetase [glutamine-hydrolyzing] 2; Glutamine-dependent asparagine synthetase 2; EC 6.3.5.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    27% identity, 92% coverage of query (138 bits)

ASNS_HUMAN / P08243 Asparagine synthetase [glutamine-hydrolyzing]; Cell cycle control protein TS11; Glutamine-dependent asparagine synthetase; EC 6.3.5.4 from Homo sapiens (Human) (see 2 papers)
P08243 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Homo sapiens (see 4 papers)
    26% identity, 91% coverage of query (137 bits)

Asns / P49088 asparagine synthetase subunit (EC 6.3.5.4) from Rattus norvegicus (see paper)
    26% identity, 88% coverage of query (136 bits)

ASN1 asparagine synthetase from Candida albicans (see paper)
    26% identity, 92% coverage of query (136 bits)

Q10MX3 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Oryza sativa Japonica Group (see paper)
    25% identity, 96% coverage of query (135 bits)

A0A1D5VHV8 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Triticum aestivum (see paper)
    26% identity, 89% coverage of query (134 bits)

A9XS73 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Phaseolus vulgaris (see paper)
    25% identity, 89% coverage of query (132 bits)

6gq3A / P08243 Human asparagine synthetase (asns) in complex with 6-diazo-5-oxo-l- norleucine (don) at 1.85 a resolution (see paper)
    26% identity, 87% coverage of query (132 bits)

Q9SM55 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Phaseolus vulgaris (see paper)
    26% identity, 88% coverage of query (131 bits)

F2CWZ7 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare subsp. vulgare (see paper)
    26% identity, 89% coverage of query (127 bits)

Q84LA5 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare (see paper)
    26% identity, 89% coverage of query (126 bits)

F2DDF6 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare subsp. vulgare (see paper)
    24% identity, 89% coverage of query (119 bits)

Q2L9S5 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Bombyx mori (see paper)
    24% identity, 91% coverage of query (119 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory