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Searching for up to 100 curated homologs for 5210635 FitnessBrowser__PV4:5210635 (129 a.a.)

Found high-coverage hits (≥70%) to 26 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Gcv / b2904 glycine cleavage system H protein from Escherichia coli K-12 substr. MG1655 (see 11 papers)
gcvH / P0A6T9 glycine cleavage system H protein from Escherichia coli (strain K12) (see 9 papers)
GCSH_ECOLI / P0A6T9 Glycine cleavage system H protein from Escherichia coli (strain K12) (see paper)
P0A6T9 glycine cleavage system (subunit 2/3) (EC 1.4.1.27) from Escherichia coli (see paper)
    74% identity, 100% coverage of query (201 bits)

3ab9A / P0A6T9 Crystal structure of lipoylated e. Coli h-protein (reduced form) (see paper)
    73% identity, 98% coverage of query (197 bits)

GCSH_THET8 / Q5SKW9 Glycine cleavage system H protein from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    57% identity, 98% coverage of query (147 bits)

PfGW456L13_1869 glycine cleavage system H protein (EC 1.4.1.27) from Pseudomonas fluorescens GW456-L13
    54% identity, 94% coverage of query (132 bits)

GCSH_STAAM / P64213 Glycine cleavage system H protein; Octanoyl/lipoyl carrier protein from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
    51% identity, 97% coverage of query (128 bits)

GCSH_ORYSJ / A3C6G9 Glycine cleavage system H protein, mitochondrial from Oryza sativa subsp. japonica (Rice) (see paper)
    54% identity, 95% coverage of query (127 bits)

GCSH_FLATR / P46485 Glycine cleavage system H protein, mitochondrial; Lipoyl-bearing H protein from Flaveria trinervia (Clustered yellowtops) (Oedera trinervia) (see 2 papers)
    50% identity, 95% coverage of query (126 bits)

P16048 glycine cleavage system (subunit 2/4) (EC 1.4.1.27) from Pisum sativum (see paper)
    50% identity, 100% coverage of query (125 bits)

1dxmA / P16048 Reduced form of the h protein from glycine decarboxylase complex (see paper)
    50% identity, 99% coverage of query (125 bits)

P16048 Glycine cleavage system H protein, mitochondrial from Pisum sativum (Garden pea) (Lathyrus oleraceus)
    50% identity, 100% coverage of query (125 bits)

1htpA Refined structures at 2 angstroms and 2.2 angstroms of the two forms of the h-protein, a lipoamide-containing protein of the glycine decarboxylase complex
    50% identity, 99% coverage of query (125 bits)

1hpcB Refined structures at 2 angstroms and 2.2 angstroms of the two forms of the h-protein, a lipoamide-containing protein of the glycine decarboxylase
    50% identity, 99% coverage of query (125 bits)

1hpcA Refined structures at 2 angstroms and 2.2 angstroms of the two forms of the h-protein, a lipoamide-containing protein of the glycine decarboxylase
    50% identity, 99% coverage of query (125 bits)

GCSH / A8HYD5 glycine cleavage system H protein (EC 1.4.1.27) from Chlamydomonas reinhardtii (see 3 papers)
    54% identity, 88% coverage of query (121 bits)

GCSH3_ARATH / Q9LQL0 Glycine cleavage system H protein 3, mitochondrial from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LQL0 glycine cleavage system (subunit 2/5) (EC 1.4.1.27) from Arabidopsis thaliana (see paper)
    50% identity, 95% coverage of query (121 bits)

GDH1 / P25855 glycine cleavage system H protein 1 (EC 1.4.1.27) from Arabidopsis thaliana (see 4 papers)
GCSH1_ARATH / P25855 Glycine cleavage system H protein 1, mitochondrial from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
P25855 glycine cleavage system (subunit 3/5) (EC 1.4.1.27); glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) from Arabidopsis thaliana (see 2 papers)
AAA87942.1 glycine decarboxylase complex H-protein precursor from Arabidopsis thaliana (see paper)
    49% identity, 95% coverage of query (120 bits)

GCSH_BACSU / O32174 Glycine cleavage system H protein; Octanoyl/lipoyl carrier protein from Bacillus subtilis (strain 168) (see paper)
    46% identity, 98% coverage of query (118 bits)

GCSH / P23434 glycine cleavage system H protein, mitochondrial (EC 1.4.1.27) from Homo sapiens (see 2 papers)
GCSH_HUMAN / P23434 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Homo sapiens (Human) (see 3 papers)
P23434 glycine cleavage system (subunit 3/4) (EC 1.4.1.27); glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) from Homo sapiens (see 3 papers)
    49% identity, 92% coverage of query (117 bits)

GCSH_BOVIN / P20821 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Bos taurus (Bovine) (see 3 papers)
P20821 glycine cleavage system (EC 1.4.1.27) from Bos taurus (see paper)
    47% identity, 92% coverage of query (114 bits)

P11183 H-protein-(lipoyl)lysine (EC 1.4.1.27) from Gallus gallus (see 3 papers)
GCSH_CHICK / P11183 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Gallus gallus (Chicken) (see 2 papers)
P11183 glycine cleavage system (subunit 2/3) (EC 1.4.1.27) from Gallus gallus (see paper)
    46% identity, 91% coverage of query (109 bits)

B0F467 glycine cleavage system (subunit 5/5) (EC 1.4.1.27) from Paratrimastix pyriformis (see paper)
    44% identity, 95% coverage of query (104 bits)

GCSH_SCHPO / Q9HDV9 Putative glycine cleavage system H protein, mitochondrial; Glycine decarboxylase complex subunit H from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    46% identity, 93% coverage of query (103 bits)

GCSH_YEAST / P39726 Glycine cleavage system H protein, mitochondrial; Glycine decarboxylase complex subunit H from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
    38% identity, 95% coverage of query (101 bits)

gcvH / P73560 glycine cleavage system H-protein (EC 1.4.1.27) from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
    47% identity, 95% coverage of query (101 bits)

Build an alignment

Build an alignment for 5210635 and 24 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

GCVHL_STAAM / A0A0H3JT43 Glycine cleavage system H-like protein; GcvH-L from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
    24% identity, 76% coverage of query (45.4 bits)

GCVHL_STRPG / P0DN69 Glycine cleavage system H-like protein; GcvH-L from Streptococcus pyogenes serotype M5 (strain Manfredo) (see paper)
    26% identity, 87% coverage of query (43.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory