Searching for up to 100 curated homologs for 5210659 FitnessBrowser__PV4:5210659 (620 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
hcuC / BAC81752.1 hydrophobic compound transport factor from Pseudomonas aeruginosa (see paper)
52% identity, 93% coverage of query (531 bits)
MITOS_RAT / Q5RKI8 Mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ABCB8; Mitochondrial sulfonylurea-receptor; MITOSUR from Rattus norvegicus (Rat) (see paper)
36% identity, 97% coverage of query (337 bits)
MITOS_HUMAN / Q9NUT2 Mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ABCB8; Mitochondrial ATP-binding cassette 1; M-ABC1; Mitochondrial sulfonylurea-receptor; MITOSUR from Homo sapiens (Human) (see 5 papers)
Q9NUT2 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
TC 3.A.1.201.22 / Q9NUT2 Mitochondrial ATP-binding cassette 1, ABCB8 from Homo sapiens
38% identity, 87% coverage of query (334 bits)
5ochE / Q9NUT2 The crystal structure of human abcb8 in an outward-facing state
38% identity, 86% coverage of query (333 bits)
ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
36% identity, 95% coverage of query (332 bits)
MITOS_MOUSE / Q9CXJ4 Mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ABCB8; Mitochondrial sulfonylurea-receptor; MITOSUR from Mus musculus (Mouse) (see paper)
36% identity, 97% coverage of query (328 bits)
ABCBA_HUMAN / Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2 from Homo sapiens (Human) (see 7 papers)
Q9NRK6 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
36% identity, 93% coverage of query (326 bits)
AB25B_ORYSJ / Q9FNU2 ABC transporter B family member 25; ABC transporter ABCB.25; OsABCB25; Protein ALS1 homolog; Protein ALUMINUM SENSITIVE 1; OsALS1 from Oryza sativa subsp. japonica (Rice) (see paper)
34% identity, 94% coverage of query (321 bits)
4ayxA / Q9NRK6 Structure of the human mitochondrial abc transporter, abcb10 (rod form b) (see paper)
36% identity, 91% coverage of query (321 bits)
Y1866_STAAM / Q99T13 Putative multidrug export ATP-binding/permease protein SAV1866; EC 7.6.2.- from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
Q99T13 ABC-type xenobiotic transporter (EC 7.6.2.2) from Staphylococcus aureus (see paper)
TC 3.A.1.106.2 / Q2G2M9 The homodimeric Sav1866 multidrug exporter (transports doxorubicin, verapamil, ethidium, tetraphenylphosphonium, vinblastine and the fluorescent dye, Hoechst 33342; 3-D structure known at 3 Å resolution; Dawson and Locher, 2006; Velamakanni et al., 2008) The empty site opens by rotation of the nucleotide-binding domain whereas the ATP-bound site remains occluded (Jones and George, 2011). Conformational changes induced by ATP-binding and hydrolysis have been proposed (Becker et al. 2010; Oliveira et al., 2011). The alternating access mechanism and the flippase activity of this ABC exporter has been shown to be lipid-dependent (Becker et al. 2010; Oliveira et al., 2011). The alternating access mechanism and the flippase activity of this ABC exporter has been shown to be lipid-dependent from Staphylococcus aureus (strain NCTC 8325)
2hydA / Q99T13 Multidrug abc transporter sav1866 (see paper)
32% identity, 93% coverage of query (311 bits)
2onjA Structure of the multidrug abc transporter sav1866 from s. Aureus in complex with amp-pnp
32% identity, 93% coverage of query (311 bits)
7y48B Cryo-em structure of biliverdin-bound mitochondrial abc transporter abcb10 from biortus
35% identity, 91% coverage of query (309 bits)
MDL1_SCHPO / Q9Y7M7 ATP-dependent permease MDL1, mitochondrial; ABC transporter mdl1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
mdl1 mitochondrial peptide-transporting ATPase from Schizosaccharomyces pombe (see 2 papers)
36% identity, 85% coverage of query (308 bits)
4aywA Structure of the human mitochondrial abc transporter, abcb10 (plate form)
35% identity, 91% coverage of query (304 bits)
MDR2_ASPFU / Q4WPP6 ABC multidrug transporter mdr2 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 4 papers)
37% identity, 82% coverage of query (303 bits)
TC 3.A.1.135.5 / Q9WYC4 Uncharacterized ABC transporter ATP-binding protein TM_0288, component of The hetrodimeric ABC transporter, TM287/TM288 from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
31% identity, 97% coverage of query (303 bits)
7ehlA Cryo-em structure of human abcb8 transporter in nucleotide binding state
37% identity, 85% coverage of query (303 bits)
5ochC / Q9NUT2 The crystal structure of human abcb8 in an outward-facing state
36% identity, 87% coverage of query (296 bits)
AB27B_ARATH / Q0WML0 ABC transporter B family member 27; ABC transporter ABCB.27; AtABCB27; Aluminum tolerance-related ATP-binding cassette transporter; Antigen peptide transporter-like 2; Transporter associated with antigen processing-like protein 2; AtTAP2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 3.A.1.201.8 / Q0WML0 The aluminum chelate (aluminum sensitivity (ALS1)) protein; expressed in root vacuoles half-type ABC transporter from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
TAP2 / RF|NP_198720.2 antigen peptide transporter-like 2 from Arabidopsis thaliana (see paper)
37% identity, 83% coverage of query (296 bits)
6quzD / Q9WYC4 Structure of atpgs-bound outward-facing tm287/288 in complex with sybody sb_tm35 (see paper)
31% identity, 93% coverage of query (296 bits)
TC 3.A.1.201.12 / B2WTH9 California mussel ABCB/MDR multixenobiotic resistance efflux pump from Mytilus californianus (see paper)
32% identity, 86% coverage of query (295 bits)
6qv0B Structure of atp-bound outward-facing tm287/288 in complex with sybody sb_tm35
31% identity, 93% coverage of query (293 bits)
TC 3.A.1.201.24 / Q00449 Multidrug exporter, MDR49 or Pgp of 1302 aas and 12 TMSs from Drosophila melanogaster
34% identity, 84% coverage of query (291 bits)
ABCB9_HUMAN / Q9NP78 ABC-type oligopeptide transporter ABCB9; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ABC transporter 9 protein; hABCB9; TAP-like protein; TAPL; EC 7.4.2.6 from Homo sapiens (Human) (see 16 papers)
Q9NP78 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see 2 papers)
TC 3.A.1.209.2 / Q9NP78 Homodimeric transporter ABCB9 or TAPL. Transports a broad spectrum of peptides (low affinity) from the cytosol to the lysosomal lumen. It exists in two forms (812 aas and 1257 aas). The latter full length protein confers resistance to taxanes and anthracyclines (Kawanobe et al., 2012). Resistance and transport were demonstrated for paclitaxel and docetaxel. TapL transports a broad range of peptides of 6-60aas (23aas optimal). It has also been detected in the ER. It is stabilized by interaction with LAMP-1 and LAMP-2 (see 9.A.16) from Homo sapiens (see 18 papers)
31% identity, 98% coverage of query (290 bits)
8gk7A / A0A6F8TGG1 Msba bound to cerastecin c
33% identity, 92% coverage of query (290 bits)
7metA A. Baumannii msba in complex with tbt1 decoupler
33% identity, 92% coverage of query (290 bits)
TC 3.A.1.201.23 / Q8T9W4 The cyclic AMP efflux pump of 1432 aas, ABCB3 from Dictyostelium discoideum
33% identity, 83% coverage of query (287 bits)
TAGA_DICDI / Q9GTN7 Serine protease/ABC transporter B family protein tagA; EC 3.4.21.- from Dictyostelium discoideum (Social amoeba) (see 3 papers)
33% identity, 85% coverage of query (285 bits)
6q81A Structure of p-glycoprotein(abcb1) in the post-hydrolytic state
36% identity, 81% coverage of query (285 bits)
3g61A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
36% identity, 81% coverage of query (285 bits)
3g60A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
36% identity, 81% coverage of query (285 bits)
ABCB9_MOUSE / Q9JJ59 ABC-type oligopeptide transporter ABCB9; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ABC transporter 9 protein; mABCB9; TAP-like protein; TAPL; EC 7.4.2.6 from Mus musculus (Mouse) (see paper)
31% identity, 95% coverage of query (284 bits)
7v5cA / Q9JJ59 Cryo-em structure of the mouse abcb9 (adp.Bef3-bound) (see paper)
31% identity, 95% coverage of query (284 bits)
MDR1_CRIGR / P21448 ATP-dependent translocase ABCB1; ATP-binding cassette sub-family B member 1; Multidrug resistance protein 1; P-glycoprotein 1; Phospholipid transporter ABCB1; CD243 antigen; EC 7.6.2.2; EC 7.6.2.1 from Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (see paper)
35% identity, 81% coverage of query (283 bits)
MDR1A_MOUSE / P21447 ATP-dependent translocase ABCB1; ATP-binding cassette sub-family B member 1A; MDR1A; Multidrug resistance protein 1A; Multidrug resistance protein 3; P-glycoprotein 3; Phospholipid transporter ABCB1; EC 7.6.2.2; EC 7.6.2.1 from Mus musculus (Mouse) (see paper)
P21447 ABC-type xenobiotic transporter (EC 7.6.2.2) from Mus musculus (see paper)
35% identity, 81% coverage of query (282 bits)
ABCB9_RAT / Q9QYJ4 ABC-type oligopeptide transporter ABCB9; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ABC transporter 9 protein; TAP-like protein; TAPL; EC 7.4.2.6 from Rattus norvegicus (Rat) (see 3 papers)
31% identity, 95% coverage of query (282 bits)
7vfiA Cryo-em structure of the mouse tapl (9mer-peptide bound)
31% identity, 93% coverage of query (282 bits)
8womA / Q9LJX0 Structure of the wild-type arabidopsis abcb19 in the brassinolide- bound state (see paper)
33% identity, 82% coverage of query (281 bits)
AB19B_ARATH / Q9LJX0 ABC transporter B family member 19; ABC transporter ABCB.19; AtABCB19; Multidrug resistance protein 11; P-glycoprotein 19 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
TC 3.A.1.201.6 / Q9LJX0 Auxin efflux pump Pgp19 (MDR11; ABCB19; ABCB21) (regulated by Twd1, an FK506-binding protein immunophilin prolyl/peptidyl isomerase (TC# 8.A.11.1.1) from Arabidopsis thaliana (Mouse-ear cress) (see 9 papers)
MDR11 / RF|NP_189528.1 multidrug resistance protein 11 from Arabidopsis thaliana (see paper)
33% identity, 82% coverage of query (281 bits)
At3g28860 / AAN28720.2 MDR-like p-glycoprotein from Arabidopsis thaliana (see paper)
33% identity, 82% coverage of query (281 bits)
TC 3.A.1.201.16 / I0DHH7 MDR efflux pump, ABCB4a from Strongylocentrotus purpuratus
33% identity, 87% coverage of query (281 bits)
4m1mA / P21447 Corrected structure of mouse p-glycoprotein (see paper)
36% identity, 80% coverage of query (281 bits)
msbA / Q2YJN8 lipid A-core oligosaccharide flippase (EC 7.5.2.6) from Brucella abortus (strain 2308) (see 2 papers)
32% identity, 93% coverage of query (281 bits)
6fn1A Zosuquidar and uic2 fab complex of human-mouse chimeric abcb1 (abcb1hm)
35% identity, 87% coverage of query (281 bits)
4q9iA P-glycoprotein cocrystallised with qz-ala
36% identity, 80% coverage of query (281 bits)
8wooA Structure of the wild-type arabidopsis abcb19 in the brassinolide and amp-pnp bound state
33% identity, 82% coverage of query (281 bits)
7zk4A The abcb1 l335c mutant (mabcb1) in the outward facing state
36% identity, 80% coverage of query (281 bits)
7otgA Structure of abcb1/p-glycoprotein in the presence of the cftr potentiator ivacaftor
36% identity, 80% coverage of query (281 bits)
7zkaA Abcb1 v978c mutant (mabcb1) in the outward facing state bound to aac
36% identity, 80% coverage of query (281 bits)
7zk6A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to 2 molecules of aac
36% identity, 80% coverage of query (281 bits)
7zk5A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to aac
36% identity, 80% coverage of query (281 bits)
4xwkA P-glycoprotein co-crystallized with bde-100
36% identity, 80% coverage of query (281 bits)
5koyA Mouse pgp 34 linker deleted bound with atp
35% identity, 80% coverage of query (280 bits)
8wp0A Structure of the arabidopsis e529q/e1174q abcb19 in the atp bound state
33% identity, 82% coverage of query (280 bits)
Build an alignment for 5210659 and 54 homologs with ≥ 30% identity
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MSBA_VIBCH / Q9KQW9 ATP-dependent lipid A-core flippase; Lipid A export ATP-binding/permease protein MsbA; EC 7.5.2.6 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see paper)
Q9KQW9 ABC-type lipopolysaccharide transporter (EC 7.5.2.5) from Vibrio cholerae (see paper)
29% identity, 93% coverage of query (279 bits)
6qeeA Nanodisc reconstituted human-mouse chimeric abcb1 (abcb1hm)-eq mutant in complex with uic2 fab and zosuquidar.
34% identity, 87% coverage of query (279 bits)
TC 3.A.1.201.15 / Q3T7C8 MDR efflux pump, ABCB1a from Strongylocentrotus purpuratus
34% identity, 84% coverage of query (276 bits)
ABCB1 / P08183 ATP-dependent translocase ABCB1 (EC 7.6.2.2) from Homo sapiens (see 39 papers)
MDR1_HUMAN / P08183 ATP-dependent translocase ABCB1; ATP-binding cassette sub-family B member 1; Multidrug resistance protein 1; P-glycoprotein 1; Phospholipid transporter ABCB1; CD243 antigen; EC 7.6.2.2; EC 7.6.2.1 from Homo sapiens (Human) (see 8 papers)
P08183 ABC-type xenobiotic transporter (EC 7.6.2.2); ABC-type glutathione-S-conjugate transporter (EC 7.6.2.3) from Homo sapiens (see 10 papers)
TC 3.A.1.201.1 / P08183 Broad specificity multidrug resistance (MDR1; MDR-1; Pgp; P-gp; ABCB1; P-glycoprotein) efflux pump. It exports organic cations and amphiphilic compounds of unrelated chemical structure from Homo sapiens (Human) (see 19 papers)
33% identity, 88% coverage of query (276 bits)
ABCB1 / RF|NP_000918.2 multidrug resistance protein 1 from Homo sapiens
33% identity, 88% coverage of query (276 bits)
TC 3.A.1.123.2 / Q93GF4 Aureocin A70 multipeptide bacteriocin (AurA, AurB, AurC, AurD) exporter, AurT from Staphylococcus aureus (see 2 papers)
30% identity, 86% coverage of query (276 bits)
MDR3_HUMAN / P21439 Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3; EC 7.6.2.1 from Homo sapiens (Human) (see 28 papers)
TC 3.A.1.201.3 / P21439 Short chain fatty acid phosphatidylcholine translocase (phospholipid flippase), MDR3; AbcB4; Pgy3 from Homo sapiens (Human) (see 15 papers)
34% identity, 80% coverage of query (276 bits)
TC 3.A.1.106.3 / Q8G7R7 Probable permease protein of ABC transporter system, component of The dimeric multidrug resistance exporter, ABC1/2 (exports the peptide antimicrobials, nisin and polymyxin; (Margolles et al., 2006) (both ABC1 and ABC2 also show striking similarity to family 3.A.1.117) from Bifidobacterium longum (see paper)
29% identity, 92% coverage of query (276 bits)
6qexA / P08183 Nanodisc reconstituted human abcb1 in complex with uic2 fab and taxol (see paper)
33% identity, 87% coverage of query (275 bits)
TC 3.A.1.117.1 / P97046 The multidrug exporter, LmrA from Lactococcus lactis (see 2 papers)
32% identity, 92% coverage of query (275 bits)
6c0vA Molecular structure of human p-glycoprotein in the atp-bound, outward- facing conformation
33% identity, 91% coverage of query (275 bits)
AB1B_ARATH / Q9ZR72 ABC transporter B family member 1; ABC transporter ABCB.1; AtABCB1; Multidrug resistance protein 1; P-glycoprotein 1; AtPgp1 from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
TC 3.A.1.201.5 / Q9ZR72 Auxin efflux pump Pgp1 (MDR1; ABCB1) (Carraro et al. 2012). Regulated by Twd1, an FK506-binding protein immunophilin prolyl/peptidyl isomerase; 8.A.11.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 14 papers)
MDR1 / RF|NP_181228.1 multidrug resistance protein 1 from Arabidopsis thaliana (see paper)
34% identity, 87% coverage of query (274 bits)
BMRA_BACSU / O06967 Multidrug resistance ABC transporter ATP-binding/permease protein BmrA; EC 7.6.2.- from Bacillus subtilis (strain 168) (see 7 papers)
TC 3.A.1.117.3 / O06967 Multidrug resistance homodimeric efflux pump, BmrA (YvcC) of 589 aas from Bacillus subtilis (strain 168)
33% identity, 93% coverage of query (274 bits)
7a6fA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and zosuquidar
34% identity, 84% coverage of query (274 bits)
7a6eA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and tariquidar
34% identity, 84% coverage of query (274 bits)
7a6cA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and elacridar
34% identity, 84% coverage of query (274 bits)
7a69A Nanodisc reconstituted human abcb1 in complex with mrk16 fab and vincristine
34% identity, 84% coverage of query (274 bits)
7o9wA Encequidar-bound human p-glycoprotein in complex with uic2-fab
34% identity, 84% coverage of query (274 bits)
MDR3_MOUSE / P21440 Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 2; Multidrug resistance protein 3; P-glycoprotein 2; P-glycoprotein 3; EC 7.6.2.1 from Mus musculus (Mouse) (see 14 papers)
31% identity, 94% coverage of query (273 bits)
AB4B_ARATH / O80725 ABC transporter B family member 4; ABC transporter ABCB.4; AtABCB4; Multidrug resistance protein 4; P-glycoprotein 4 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 3.A.1.201.7 / O80725 Auxin efflux pump Pgp4; AbcB4; MDR4; PGP4 (Lefèvre and Boutry 2018) of 1286 aas and 12 TMSs in a MCMC domain arrangement from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
MDR4 / RF|NP_182223.1 multidrug resistance protein 4; EC 3.6.3.44 from Arabidopsis thaliana (see paper)
33% identity, 85% coverage of query (273 bits)
MDR3_RAT / Q08201 Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 2; Multidrug resistance protein 3; P-glycoprotein 2; P-glycoprotein 3; EC 7.6.2.1 from Rattus norvegicus (Rat) (see 3 papers)
Q08201 ABC-type xenobiotic transporter (EC 7.6.2.2) from Rattus norvegicus (see paper)
34% identity, 81% coverage of query (272 bits)
7niwA / P21439 Nanodisc reconstituted human abcb4 in complex with 4b1-fab (posaconazole-bound, inward-open conformation) (see paper)
34% identity, 79% coverage of query (271 bits)
7ow8A / O06967 Cryoem structure of the abc transporter bmra e504a mutant in complex with atp-mg (see paper)
33% identity, 93% coverage of query (271 bits)
6s7pA Nucleotide bound abcb4
34% identity, 79% coverage of query (271 bits)
YWJA_BACSU / P45861 Uncharacterized ABC transporter ATP-binding protein YwjA from Bacillus subtilis (strain 168) (see 2 papers)
32% identity, 85% coverage of query (270 bits)
MDR1_CRYNH / J9VF33 ABC multidrug transporter MDR1 from Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) (see 2 papers)
TC 3.A.1.201.11 / O43140 Mdr1 azole resistance efflux pump from Cryptococcus neoformans (see paper)
34% identity, 84% coverage of query (270 bits)
TC 3.A.1.135.8 / Q837P4 ABC transporter, ATP-binding/permease protein, component of Multidrug efflux pump, EfrCD from Enterococcus faecalis (strain ATCC 700802 / V583)
31% identity, 84% coverage of query (270 bits)
TC 3.A.1.201.25 / A5X7X7 MDR transporter, Crmdr1 of 1266 aas and 12 TMSs from Catharanthus roseus
33% identity, 91% coverage of query (269 bits)
MsbA / b0914 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli K-12 substr. MG1655 (see 54 papers)
msbA / P60752 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli (strain K12) (see 57 papers)
MSBA_ECOLI / P60752 ATP-dependent lipid A-core flippase; Lipid A export ATP-binding/permease protein MsbA; Lipid flippase; EC 7.5.2.6 from Escherichia coli (strain K12) (see 17 papers)
P60752 ABC-type lipid A-core oligosaccharide transporter (EC 7.5.2.6); P-type phospholipid transporter (EC 7.6.2.1) from Escherichia coli (see 13 papers)
TC 3.A.1.106.1 / P60752 Phospholipid, LPS, lipid A and drug exporter, MsbA, which flips the substrate from the inner leaflet of the cytoplasmic membrane to the outer leaflet (Eckford and Sharom, 2010). MsbA also confers drug resistance to azidopine, daunomycin, vinblastine, Hoechst 33342 and ethidium (Reuter et al., 2003). Four x-ray structures, trapped in different conformations, two with and two without nucleotide, have been solved (Ward et al., 2007). They suggest an alternating accessibility mode of transport with major conformational changes from Escherichia coli (see 11 papers)
msbA / MB|P60752 lipid A export ATP-binding/permease protein msbA; EC 3.6.3.- from Escherichia coli K12 (see 24 papers)
28% identity, 93% coverage of query (268 bits)
6bppA E. Coli msba in complex with lps and inhibitor g092
28% identity, 92% coverage of query (268 bits)
6bplA E. Coli msba in complex with lps and inhibitor g907
28% identity, 92% coverage of query (268 bits)
8dmmA Structure of the vanadate-trapped msba bound to kdl
28% identity, 93% coverage of query (268 bits)
7ph2A Nanodisc reconstituted msba in complex with nanobodies, spin-labeled at position a60c
28% identity, 93% coverage of query (268 bits)
7mewA E. Coli msba in complex with g247
28% identity, 92% coverage of query (268 bits)
7ph3A / P60752 Amp-pnp bound nanodisc reconstituted msba with nanobodies, spin- labeled at position a60c (see paper)
28% identity, 92% coverage of query (268 bits)
7bcwA Structure of msba in salipro with adp vanadate
28% identity, 92% coverage of query (268 bits)
6rajA Heterodimeric abc exporter tmrab in vanadate trapped outward-facing open conformation
33% identity, 87% coverage of query (267 bits)
6rafA / Q72J05 Heterodimeric abc exporter tmrab in inward-facing narrow conformation under turnover conditions (see paper)
33% identity, 87% coverage of query (267 bits)
6ragA Heterodimeric abc exporter tmrab in inward-facing wide conformation under turnover conditions
33% identity, 87% coverage of query (267 bits)
7t55A / A3DCU1 Cryo-em structure of pcat1 in the inward-facing wide conformation under atp turnover condition (see paper)
29% identity, 93% coverage of query (265 bits)
7bg4A Multidrug resistance transporter bmra mutant e504a bound with atp, mg, and rhodamine 6g solved by cryo-em
33% identity, 93% coverage of query (264 bits)
6quzA Structure of atpgs-bound outward-facing tm287/288 in complex with sybody sb_tm35
29% identity, 93% coverage of query (262 bits)
4q4aA / Q9WYC3 Improved model of amp-pnp bound tm287/288 (see paper)
29% identity, 93% coverage of query (262 bits)
4s0fA Crystal structure of the peptidase-containing abc transporter pcat1 e648q mutant complexed with atpgs in an occluded conformation
29% identity, 92% coverage of query (262 bits)
7selA E. Coli msba in complex with lps and inhibitor g7090 (compound 3)
28% identity, 92% coverage of query (262 bits)
MDL1_YEAST / P33310 ATP-dependent permease MDL1, mitochondrial; ABC transporter MDL1; Multidrug resistance-like protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
TC 3.A.1.212.1 / P33310 The mitochondrial peptide exporter, Mdl1p (exports peptides of 6-21 amino acyl residues from the mitochondrial matrix as well as degradation products of misassembled respiratory chain complexes) (Janas et al., 2003; van der Does et al., 2006; Gompf et al., 2007). A leaderless Mdl1p targets to the ER membrane instead of to the mitochondria from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
MDL1 / RF|NP_013289.1 ATP-dependent permease MDL1, mitochondrial; EC 3.6.3.43 from Saccharomyces cerevisiae (see paper)
33% identity, 83% coverage of query (262 bits)
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