Searching for up to 100 curated homologs for 5210989 FitnessBrowser__PV4:5210989 (268 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
HSD1 / P0DKC5 11β-, 17β-hydroxysteroid dehydrogenase / 17β-ketosteroid reductase (EC 1.1.1.62; EC 1.1.1.146) from Arabidopsis thaliana (see 3 papers)
HSD1A_ARATH / P0DKC5 11-beta-hydroxysteroid dehydrogenase 1A; 17-beta-hydroxysteroid dehydrogenase 1A; Hydroxysteroid dehydrogenase 1; AtHSD1; EC 1.1.1.146; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
HSD1B_ARATH / P0DKC6 11-beta-hydroxysteroid dehydrogenase 1B; 17-beta-hydroxysteroid dehydrogenase 1B; Hydroxysteroid dehydrogenase 1; AtHSD1; EC 1.1.1.146; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
33% identity, 99% coverage of query (155 bits)
HSDA_SESIN / Q93W57 11-beta-hydroxysteroid dehydrogenase A; 17-beta-hydroxysteroid dehydrogenase A; Seed oil body protein 2; Steroleosin-A; EC 1.1.1.-; EC 1.1.1.62 from Sesamum indicum (Oriental sesame) (Sesamum orientale) (see 3 papers)
33% identity, 97% coverage of query (154 bits)
HSDA_ARAHY / A7LB60 11-beta-hydroxysteroid dehydrogenase A; 17-beta-hydroxysteroid dehydrogenase A; Steroleosin-A; EC 1.1.1.146; EC 1.1.1.- from Arachis hypogaea (Peanut) (see paper)
35% identity, 97% coverage of query (149 bits)
DHRS7_HUMAN / Q9Y394 Dehydrogenase/reductase SDR family member 7; Retinal short-chain dehydrogenase/reductase 4; retSDR4; Short chain dehydrogenase/reductase family 34C member 1; Protein SDR34C1; EC 1.1.1.- from Homo sapiens (Human) (see 5 papers)
35% identity, 98% coverage of query (143 bits)
HSD_PINMS / A0A140FAN3 11-beta-hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase; Steroleosin; EC 1.1.1.146; EC 1.1.1.62 from Pinus massoniana (Chinese red pine) (see paper)
33% identity, 97% coverage of query (138 bits)
DRS7B_RAT / Q5RJY4 Dehydrogenase/reductase SDR family member 7B; Short-chain dehydrogenase/reductase family 32C member 1; Protein SDR32C1; EC 1.1.-.- from Rattus norvegicus (Rat) (see 2 papers)
31% identity, 96% coverage of query (130 bits)
V9NF79 diacetyl reductase [(R)-acetoin forming] (EC 1.1.1.303) from Paenibacillus polymyxa (see paper)
35% identity, 71% coverage of query (107 bits)
ACR1_ACIAD / Q6F7B8 Fatty acyl-CoA reductase; EC 1.2.1.n2 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6F7B8 hexadecanal dehydrogenase (acylating) (EC 1.2.1.42) from Acinetobacter baylyi (see paper)
30% identity, 95% coverage of query (105 bits)
phaB / BAC45231.1 3-keto-acyl-CoA reductase from Bacillus sp. INT005 (see paper)
36% identity, 72% coverage of query (103 bits)
HSDB_ARAHY / A7LB59 11-beta-hydroxysteroid dehydrogenase B; 17-beta-hydroxysteroid dehydrogenase B; Steroleosin-B; EC 1.1.1.146; EC 1.1.1.- from Arachis hypogaea (Peanut) (see paper)
30% identity, 82% coverage of query (103 bits)
3gmdA Structure-based design of 7-azaindole-pyrrolidines as inhibitors of 11beta-hydroxysteroid-dehydrogenase type i
32% identity, 87% coverage of query (103 bits)
Q8RR58 long-chain acyl-protein thioester reductase (EC 1.2.1.50) from Acinetobacter sp. (see paper)
30% identity, 95% coverage of query (102 bits)
4nmhA 11-beta-hsd1 in complex with a 3,3-di-methyl-azetidin-2-one
32% identity, 87% coverage of query (102 bits)
4k26A / P50172 4,4-dioxo-5,6-dihydro-[1,4,3]oxathiazines, a novel class of 11 -hsd1 inhibitors for the treatment of diabetes (see paper)
32% identity, 87% coverage of query (100 bits)
DHI1_MOUSE / P50172 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1; 11-beta-hydroxysteroid dehydrogenase/microsomal carbonyl reductase; 11-beta-HSD1A/MCR; 11beta-HSD1A; 7-oxosteroid reductase; Corticosteroid 11-beta-dehydrogenase isozyme 1; liver-type 11-beta-HSD; EC 1.1.1.146; EC 1.1.1.201 from Mus musculus (Mouse) (see 5 papers)
P50172 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146) from Mus musculus (see 14 papers)
32% identity, 87% coverage of query (100 bits)
bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
30% identity, 79% coverage of query (100 bits)
5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
30% identity, 79% coverage of query (100 bits)
5qijA Crystal structure of murine 11b- hydroxysteroiddehydrogenase complexed with 2-(3-(1-(4- chlorophenyl)cyclopropyl)-[1,2,4]triazolo[4,3- a]pyridin-8- yl)propan-2-ol
32% identity, 87% coverage of query (100 bits)
5pgzA Crystal structure of murine 11beta- hydroxysteroiddehydrogenase complexed with 2-[(5r,7s)-6-hydroxy-2-phenyladamantan-2-yl]-1-(3- hydroxyazetidin-1-yl)ethan-1-one (bms-816336)
32% identity, 87% coverage of query (100 bits)
1y5rA The crystal structure of murine 11b-hydroxysteroid dehydrogenase complexed with corticosterone
32% identity, 87% coverage of query (100 bits)
4ijuB / P28845 Crystal structure of 11b-hsd1 double mutant (l262r, f278e) in complex with (1s,4s)-4-[8-(2-fluorophenoxy)[1,2,4]triazolo[4,3-a]pyridin-3- yl]bicyclo[2.2.1]heptan-1-ol (see paper)
34% identity, 74% coverage of query (98.6 bits)
3fcoA Crystal structure of 11beta-hydroxysteroid dehydrogenase 1 (11b-hsd1) in complex with benzamide inhibitor
34% identity, 75% coverage of query (98.6 bits)
3hfgA Crystal structure of human 11-beta-hydroxysteroid-dehydrogenase bound to an sulfonyl-piperazine inhibitor
34% identity, 74% coverage of query (98.6 bits)
3byzA 2-amino-1,3-thiazol-4(5h)-ones as potent and selective 11- hydroxysteroid dehydrogenase type 1 inhibitors
34% identity, 74% coverage of query (98.6 bits)
3qqpA Crystal structure of 11beta-hydroxysteroid dehydrogenase 1 (11b-hsd1) in complex with urea inhibitor
34% identity, 74% coverage of query (98.6 bits)
PK81I_PSEFD / M2ZIX7 Short chain dehydrogenase MYCFIDRAFT_6125; PKS8-1 gene cluster protein MYCFIDRAFT_6125; EC 1.1.1.- from Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease fungus) (Mycosphaerella fijiensis) (see 2 papers)
35% identity, 78% coverage of query (98.2 bits)
HSD11B1 / P28845 corticosteroid 11-beta-dehydrogenase isozyme 1 (EC 1.1.1.146) from Homo sapiens (see 7 papers)
DHI1_HUMAN / P28845 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1; 7-oxosteroid reductase; Corticosteroid 11-beta-dehydrogenase isozyme 1; Short chain dehydrogenase/reductase family 26C member 1; EC 1.1.1.146; EC 1.1.1.201 from Homo sapiens (Human) (see 22 papers)
P28845 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146) from Homo sapiens (see 51 papers)
34% identity, 74% coverage of query (98.2 bits)
3ey4A Further studies with the 2-amino-1,3-thiazol-4(5h)-one class of 11- hydroxysteroid dehydrogenase type 1 (11-hsd1) inhibitors: reducing pregnane x receptor (pxr) activity and exploring activity in a monkey pharmacodynamic model
34% identity, 74% coverage of query (98.2 bits)
3pdjA Crystal structure of human 11-beta-hydroxysteroid dehydrogenase 1 (11b-hsd1) in complex with 4,4-disubstituted cyclohexylbenzamide inhibitor
34% identity, 74% coverage of query (98.2 bits)
2rbeA The discovery of 2-anilinothiazolones as 11beta-hsd1 inhibitors
34% identity, 74% coverage of query (98.2 bits)
5pgyA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-[(5r,7s)-6-hydroxy-2-phenyladamantan-2-yl]-1-(3- hydroxyazetidin-1-yl)ethan-1-one (bms-816336)
34% identity, 74% coverage of query (98.2 bits)
4ijwA Crystal structure of 11b-hsd1 double mutant (l262r, f278e) in complex with 3-[1-(4-chlorophenyl)cyclopropyl]-8-cyclopropyl[1,2, 4]triazolo[4,3-a]pyridine
34% identity, 74% coverage of query (98.2 bits)
5pgwA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-[(1r,3s,5r,7s)-2-[4-(4-fluorophenyl)phenyl]-6- hydroxyadamantan-2-yl]-1-(3- hydroxyazetidin-1-yl)ethan-1-one
34% identity, 74% coverage of query (98.2 bits)
3d3eA Crystal structure of human 11-beta-hydroxysteroid dehydrogenase (hsd1) in complex with benzamide inhibitor
34% identity, 74% coverage of query (98.2 bits)
4hx5A Crystal structure of 11 beta-hsd1 in complex with sar184841
34% identity, 74% coverage of query (98.2 bits)
3oq1A Crystal structure of 11beta-hydroxysteroid dehydrogenase-1 (11b-hsd1) in complex with diarylsulfone inhibitor
34% identity, 74% coverage of query (98.2 bits)
3h6kA Crystal structure of human 11-beta-hydroxysteroid-dehydrogenase bound to an ortho-chlro-sulfonyl-piperazine inhibitor
34% identity, 74% coverage of query (98.2 bits)
5qiiA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-(3-(1-(4-chlorophenyl)cyclopropyl) -[1,2, 4]triazolo[4,3-a]pyridin-8-yl)propan-2-ol
34% identity, 74% coverage of query (98.2 bits)
5pgxA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-(2-benzyl-6-hydroxyadamantan-2-yl)-1-(3- hydroxyazetidin-1-yl)ethan-1-one
34% identity, 74% coverage of query (98.2 bits)
5pgvA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 1-(3-hydroxyazetidin-1-yl)-2-[(2s,5r)-2-(4- fluorophenyl)-5-methoxyadamantan-2-yl]ethan-1-one
34% identity, 74% coverage of query (98.2 bits)
5pguA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-[2-(4-fluorophenyl)-2-adamantyl]-1-(3- methoxyazetidin-1-yl)ethanone
34% identity, 74% coverage of query (98.2 bits)
3tfqA Crystal structure of 11b-hsd1 double mutant (l262r, f278e) complexed with 8-{[(2-cyanopyridin-3-yl)methyl]sulfanyl}-6-hydroxy-3,4-dihydro- 1h-pyrano[3,4-c]pyridine-5-carbonitrile
34% identity, 74% coverage of query (98.2 bits)
3czrA Crystal structure of human 11-beta-hydroxysteroid dehydrogenase (hsd1) in complex with arylsulfonylpiperazine inhibitor
34% identity, 74% coverage of query (98.2 bits)
3frjB Crystal structure of 11b-hydroxysteroid dehydrogenase-1 (11b-hsd1) in complex with piperidyl benzamide inhibitor
34% identity, 74% coverage of query (98.2 bits)
4k1lA 4,4-dioxo-5,6-dihydro-[1,4,3]oxathiazines, a novel class of 11 beta- hsd1 inhibitors for the treatment of diabetes
34% identity, 74% coverage of query (98.2 bits)
2belA Structure of human 11-beta-hydroxysteroid dehydrogenase in complex with NADP and carbenoxolone
34% identity, 74% coverage of query (98.2 bits)
1xu7A Crystal structure of the interface open conformation of tetrameric 11b-hsd1
34% identity, 74% coverage of query (98.2 bits)
2iltA Human 11-beta-hydroxysteroid dehydrogenase (hsd1) with NADP and adamantane sulfone inhibitor
34% identity, 74% coverage of query (98.2 bits)
4yyzA 11b-hydroxysteroid dehydrogenase type i in complex with inhibitor
34% identity, 74% coverage of query (98.2 bits)
4ijvA Crystal structure of 11b-hsd1 double mutant (l262r, f278e) in complex with 3-[1-(4-chlorophenyl)cyclopropyl]-8-(2-fluorophenoxy)[1,2, 4]triazolo[4,3-a]pyridine
34% identity, 74% coverage of query (98.2 bits)
3ch6A Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with (3,3-dimethylpiperidin-1-yl)(6-(3-fluoro-4- methylphenyl)pyridin-2-yl)methanone
34% identity, 74% coverage of query (98.2 bits)
4c7kA 11b-hydroxysteroid dehydrogenase type i in complex with inhibitor
34% identity, 74% coverage of query (98.2 bits)
4c7jA 11b-hydroxysteroid dehydrogenase type i in complex with inhibitor
34% identity, 74% coverage of query (98.2 bits)
3bzuA Crystal structure of human 11-beta-hydroxysteroid dehydrogenase(hsd1) in complex with NADP and thiazolone inhibitor
34% identity, 74% coverage of query (98.2 bits)
2irwA Human 11-beta-hydroxysteroid dehydrogenase (hsd1) with NADP and adamantane ether inhibitor
34% identity, 74% coverage of query (98.2 bits)
DHI1_RAT / P16232 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1; 7-oxosteroid reductase; Corticosteroid 11-beta-dehydrogenase isozyme 1; EC 1.1.1.146; EC 1.1.1.201 from Rattus norvegicus (Rat) (see 6 papers)
P16232 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146) from Rattus norvegicus (see 4 papers)
33% identity, 74% coverage of query (97.8 bits)
DHI1_MESAU / Q6R0J2 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1; 7-alpha-hydroxycholesterol dehydrogenase; 7-alpha-HCD; 7-oxosteroid reductase; Corticosteroid 11-beta-dehydrogenase isozyme 1; EC 1.1.1.146; EC 1.1.1.201 from Mesocricetus auratus (Golden hamster) (see 2 papers)
Q6R0J2 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146) from Mesocricetus auratus (see paper)
33% identity, 79% coverage of query (97.8 bits)
4bb6A Free-wilson and structural approaches to co-optimising human and rodent isoform potency for 11b-hydroxysteroid dehydrogenase type 1 11b-hsd1 inhibitors
34% identity, 74% coverage of query (97.8 bits)
4bb5A Free-wilson and structural approaches to co-optimising human and rodent isoform potency for 11b-hydroxysteroid dehydrogenase type 1 11b-hsd1 inhibitors
34% identity, 74% coverage of query (97.8 bits)
4p38A Human 11beta-hydroxysteroid dehydrogenase type 1 in complex with azd8329
34% identity, 74% coverage of query (97.8 bits)
5ha5D Crystal structure of an NAD-bound oxidoreductase from brucella ovis
31% identity, 74% coverage of query (97.4 bits)
5itvD / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
32% identity, 71% coverage of query (97.1 bits)
Build an alignment for 5210989 and 62 homologs with ≥ 30% identity
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YI13_SCHPO / Q9P7B4 NADP-dependent 3-hydroxy acid dehydrogenase; L-allo-threonine dehydrogenase; EC 1.1.1.381 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
29% identity, 90% coverage of query (96.7 bits)
DHI1_BOVIN / Q8HZJ8 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1; 11HSD1; 7-oxosteroid reductase; Corticosteroid 11-beta-dehydrogenase isozyme 1; EC 1.1.1.146; EC 1.1.1.201 from Bos taurus (Bovine) (see 2 papers)
32% identity, 79% coverage of query (96.3 bits)
G0HY85 acetoacetyl-CoA reductase (EC 1.1.1.36) from Haloarcula hispanica (see paper)
33% identity, 71% coverage of query (96.3 bits)
fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
31% identity, 77% coverage of query (95.9 bits)
FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
31% identity, 79% coverage of query (94.7 bits)
3rkuA / Q05016 Substrate fingerprint and the structure of NADP+ dependent serine dehydrogenase from saccharomyces cerevisiae complexed with NADP+
33% identity, 89% coverage of query (94.0 bits)
YM71_YEAST / Q05016 NADP-dependent 3-hydroxy acid dehydrogenase; L-allo-threonine dehydrogenase; EC 1.1.1.-; EC 1.1.1.381 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
Q05016 3-hydroxy acid dehydrogenase (EC 1.1.1.381) from Saccharomyces cerevisiae (see paper)
33% identity, 89% coverage of query (94.0 bits)
AF255341 / Q9NBB5 3-dehydroecdysone-3α-reductase from Spodoptera littoralis (see 3 papers)
31% identity, 78% coverage of query (93.2 bits)
1xhlA / Q19774 Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
32% identity, 70% coverage of query (93.2 bits)
1xhlB Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
32% identity, 70% coverage of query (93.2 bits)
6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
31% identity, 73% coverage of query (92.0 bits)
FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
31% identity, 73% coverage of query (92.0 bits)
1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
31% identity, 73% coverage of query (92.0 bits)
3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
31% identity, 74% coverage of query (91.7 bits)
Q9AE70 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Pseudomonas putida (see 2 papers)
30% identity, 81% coverage of query (91.7 bits)
2q2qD / Q9AE70 Structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida (see paper)
30% identity, 81% coverage of query (91.7 bits)
SADH_MYCTU / P9WGP9 Putative oxidoreductase SadH; EC 1.-.-.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
34% identity, 75% coverage of query (91.3 bits)
6ci9D / A0QP46 Rmm microcompartment-associated aminopropanol dehydrogenase NADP + aminoacetone holo-structure (see paper)
32% identity, 72% coverage of query (91.3 bits)
Q2KIJ5 3-dehydrosphinganine reductase (EC 1.1.1.102) from Bos taurus (see paper)
30% identity, 84% coverage of query (90.9 bits)
KDSR_BACTN / Q8A945 3-ketodihydrosphingosine reductase; 3-KDSR; KDS reductase; EC 1.1.1.102 from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) (see paper)
29% identity, 80% coverage of query (90.9 bits)
aknA / Q9L553 aclacinomycin polyketide synthase reductase from Streptomyces galilaeus (see paper)
32% identity, 75% coverage of query (90.9 bits)
Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
31% identity, 70% coverage of query (90.5 bits)
FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
31% identity, 73% coverage of query (90.1 bits)
1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
30% identity, 73% coverage of query (90.1 bits)
4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
31% identity, 72% coverage of query (90.1 bits)
ACT3_STRCO / P16544 Putative ketoacyl reductase; EC 1.3.1.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 2 papers)
34% identity, 71% coverage of query (89.7 bits)
2rh4B / P16544 Actinorhodin ketoreductase, actkr, with NADPH and inhibitor emodin (see paper)
34% identity, 71% coverage of query (89.4 bits)
1edoA / Q93X62 The x-ray structure of beta-keto acyl carrier protein reductase from brassica napus complexed with NADP+ (see paper)
29% identity, 76% coverage of query (89.4 bits)
4qecA / I6ZQW6 Elxo with NADP bound (see paper)
28% identity, 72% coverage of query (89.4 bits)
6d9yB / B2JLJ0 Crystal structure of a short chain dehydrogenase/reductase sdr from burkholderia phymatum with partially occupied NAD
33% identity, 71% coverage of query (88.6 bits)
3rkrA / B2BKB1 Crystal structure of a metagenomic short-chain oxidoreductase (sdr) in complex with NADP (see paper)
32% identity, 71% coverage of query (88.2 bits)
7emgB / A0A0G8B235 Carbonyl reductase variant 4 (r123c/l209p/f183y/v61k) from serratia marcescens complexed with NADP+ (see paper)
30% identity, 73% coverage of query (87.4 bits)
2jahC / Q9LCV7 Biochemical and structural analysis of the clavulanic acid dehydeogenase (cad) from streptomyces clavuligerus (see paper)
36% identity, 71% coverage of query (85.9 bits)
2japA Clavulanic acid dehydrogenase: structural and biochemical analysis of the final step in the biosynthesis of the beta- lactamase inhibitor clavulanic acid
36% identity, 71% coverage of query (85.9 bits)
4dmmB / Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase from synechococcus elongatus pcc 7942 in complex with NADP
29% identity, 71% coverage of query (85.1 bits)
TR1 / P50162 tropinone reductase (EC 1.1.1.206) from Datura stramonium (see paper)
TRN1_DATST / P50162 Tropinone reductase 1; Tropine dehydrogenase; Tropinone reductase I; TR-I; EC 1.1.1.206 from Datura stramonium (Jimsonweed) (Common thornapple) (see 2 papers)
P50162 tropinone reductase I (EC 1.1.1.206) from Datura stramonium (see 2 papers)
30% identity, 79% coverage of query (84.3 bits)
1ae1B / P50162 Tropinone reductase-i complex with NADP (see paper)
30% identity, 79% coverage of query (84.3 bits)
4fn4A / Q4J9F2 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius (see paper)
31% identity, 72% coverage of query (84.3 bits)
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Lawrence Berkeley National Laboratory