Searching for up to 100 curated homologs for 5211244 FitnessBrowser__PV4:5211244 (451 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
5u1oB / Q87TK1 2.3 angstrom resolution crystal structure of glutathione reductase from vibrio parahaemolyticus in complex with fad.
75% identity, 100% coverage of query (696 bits)
5vdnA / Q8CZL0 1.55 angstrom resolution crystal structure of glutathione reductase from yersinia pestis in complex with fad
69% identity, 100% coverage of query (641 bits)
GorA / b3500 glutathione reductase (NADPH) (EC 1.8.1.7) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
gor / P06715 glutathione reductase (NADPH) (EC 1.8.1.7) from Escherichia coli (strain K12) (see 31 papers)
gor / GB|AAC76525.1 glutathione reductase; EC 1.8.1.7 from Escherichia coli K12 (see 6 papers)
68% identity, 100% coverage of query (630 bits)
P06715 Glutathione reductase; GR; GRase; EC 1.8.1.7 from Escherichia coli (strain K12)
68% identity, 100% coverage of query (630 bits)
1gerB / P06715 The structure of glutathione reductase from escherichia coli at 1.86 angstroms resolution: comparison with the enzyme from human erythrocytes (see paper)
68% identity, 100% coverage of query (627 bits)
1getA Anatomy of an engineered NAD-binding site
68% identity, 100% coverage of query (627 bits)
1geuA Anatomy of an engineered NAD-binding site
67% identity, 100% coverage of query (608 bits)
5v36A / Q8DUR5 1.88 angstrom resolution crystal structure of glutathione reductase from streptococcus mutans ua159 in complex with fad
66% identity, 100% coverage of query (601 bits)
6n7fA / Q9A0E2 1.90 angstrom resolution crystal structure of glutathione reductase from streptococcus pyogenes in complex with fad.
63% identity, 100% coverage of query (595 bits)
6b4oA / Q82Z09 1.73 angstrom resolution crystal structure of glutathione reductase from enterococcus faecalis in complex with fad
61% identity, 99% coverage of query (544 bits)
6du7A / A0A0U0ARX4 Glutathione reductase from streptococcus pneumoniae (see paper)
58% identity, 96% coverage of query (524 bits)
GSHR_DICDI / Q8T137 Glutathione reductase; GR; GRase; GSR; EC 1.8.1.7 from Dictyostelium discoideum (Social amoeba) (see paper)
51% identity, 99% coverage of query (458 bits)
Q9NL96 glutathione-disulfide reductase (EC 1.8.1.7) from Physarum polycephalum (see paper)
54% identity, 100% coverage of query (457 bits)
2rabA Structure of glutathione amide reductase from chromatium gracile in complex with NAD
51% identity, 100% coverage of query (456 bits)
GASHR_MARGR / D0VWY5 Glutathione amide reductase; GAR; EC 1.8.1.16 from Marichromatium gracile (Chromatium gracile) (see 2 papers)
51% identity, 100% coverage of query (455 bits)
5grtA Human glutathione reductase a34e, r37w mutant, glutathionylspermidine complex
52% identity, 99% coverage of query (454 bits)
4grtA Human glutathione reductase a34e, r37w mutant, mixed disulfide between trypanothione and the enzyme
52% identity, 99% coverage of query (454 bits)
3grtA Human glutathione reductase a34e, r37w mutant, oxidized trypanothione complex
52% identity, 99% coverage of query (454 bits)
2grtA Human glutathione reductase a34e, r37w mutant, oxidized glutathione complex
52% identity, 99% coverage of query (454 bits)
2r9zB / D0VWY5 Glutathione amide reductase from chromatium gracile (see paper)
51% identity, 100% coverage of query (450 bits)
GSHR_CAEEL / Q93379 Glutathione reductase, mitochondrial; GR; Glutathione disulfide reductase; EC 1.8.1.7 from Caenorhabditis elegans (see 2 papers)
Q93379 glutathione-disulfide reductase (EC 1.8.1.7) from Caenorhabditis elegans (see paper)
55% identity, 100% coverage of query (447 bits)
GSR / P00390 glutathione reductase subunit (EC 1.8.1.7) from Homo sapiens (see 6 papers)
GSHR_HUMAN / P00390 Glutathione reductase, mitochondrial; GR; GRase; EC 1.8.1.7 from Homo sapiens (Human) (see 2 papers)
52% identity, 99% coverage of query (446 bits)
3djjA / P00390 Catalytic cycle of human glutathione reductase near 1 a resolution (see paper)
52% identity, 99% coverage of query (446 bits)
4gr1A The binding of the retro-analogue of glutathione disulfide to glutathione reductase
52% identity, 99% coverage of query (446 bits)
3sqpA Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity
52% identity, 99% coverage of query (446 bits)
2gh5A Crystal structure of human glutathione reductase complexed with a fluoro-analogue of the menadione derivative m5
52% identity, 99% coverage of query (446 bits)
2aaqA Crystal structure analysis of the human glutahione reductase, complexed with gopi
52% identity, 99% coverage of query (446 bits)
1xanA Human glutathione reductase in complex with a xanthene inhibitor
52% identity, 99% coverage of query (446 bits)
1grbA Substrate binding and catalysis by glutathione reductase as derived from refined enzyme: substrate crystal structures at 2 angstroms resolution
52% identity, 99% coverage of query (446 bits)
1dncA Human glutathione reductase modified by diglutathione-dinitroso-iron
52% identity, 99% coverage of query (446 bits)
1bwcA Structure of human glutathione reductase complexed with ajoene inhibitor and subversive substrate
52% identity, 99% coverage of query (446 bits)
2hqmA / P41921 Crystal structure of glutathione reductase glr1 from the yeast saccharomyces cerevisiae (see paper)
51% identity, 100% coverage of query (442 bits)
GSHR_YEAST / P41921 Glutathione reductase; GR; GRase; EC 1.8.1.7 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
51% identity, 100% coverage of query (440 bits)
GSHR_SCHPO / P78965 Glutathione reductase; GR; GRase; EC 1.8.1.7 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
pgr1 / RF|NP_595589.1 glutathione reductase from Schizosaccharomyces pombe (see 2 papers)
51% identity, 100% coverage of query (429 bits)
Q59NQ5 glutathione-disulfide reductase (EC 1.8.1.7) from Candida albicans (see paper)
GLR1 glutathione oxidoreductase from Candida albicans (see paper)
49% identity, 99% coverage of query (429 bits)
F1LRE1 glutathione-disulfide reductase (EC 1.8.1.7) from Rattus norvegicus (see paper)
50% identity, 91% coverage of query (412 bits)
glrA hypothetical glutathione reductase (Eurofung) from Emericella nidulans (see paper)
48% identity, 100% coverage of query (386 bits)
P42770 glutathione-disulfide reductase (EC 1.8.1.7) from Arabidopsis thaliana (see 2 papers)
41% identity, 99% coverage of query (350 bits)
GSHRP_PEA / P27456 Glutathione reductase, chloroplastic/mitochondrial; GR; GRase; GOR1; EC 1.8.1.7 from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see paper)
41% identity, 99% coverage of query (349 bits)
1onfA / Q94655 Crystal structure of plasmodium falciparum glutathione reductase (see paper)
43% identity, 99% coverage of query (342 bits)
GSHR_PLAF7 / O15770 Glutathione reductase; GRase; PfGR; EC 1.8.1.7 from Plasmodium falciparum (isolate 3D7) (see 2 papers)
40% identity, 99% coverage of query (337 bits)
GSHR_PLAFK / Q94655 Glutathione reductase; GRase; PfGR; EC 1.8.1.7 from Plasmodium falciparum (isolate K1 / Thailand) (see 3 papers)
40% identity, 99% coverage of query (336 bits)
A8CCK2 glutathione-disulfide reductase (EC 1.8.1.7) from Hordeum vulgare (see paper)
39% identity, 99% coverage of query (336 bits)
GB|AAC43334 glutathione reductase; EC 1.8.1.7 from Burkholderia cepacia (see paper)
39% identity, 99% coverage of query (305 bits)
P48642 glutathione-disulfide reductase (EC 1.8.1.7) from Oryza sativa (see 2 papers)
38% identity, 99% coverage of query (305 bits)
A8CCK8 glutathione-disulfide reductase (EC 1.8.1.7) from Hordeum vulgare (see paper)
38% identity, 99% coverage of query (303 bits)
A0A068EUE1 glutathione-disulfide reductase (EC 1.8.1.7) from Cenchrus americanus (see paper)
37% identity, 99% coverage of query (303 bits)
TRXR1_EMIHU / B9A1H3 Thioredoxin reductase SEP1; EhSEP1; EC 1.8.1.9 from Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) (see paper)
B9A1H3 thioredoxin-disulfide reductase (EC 1.8.1.9) from Emiliania huxleyi (see paper)
40% identity, 99% coverage of query (300 bits)
D5LPR3 glutathione-disulfide reductase (EC 1.8.1.7) from Hevea brasiliensis (see paper)
38% identity, 99% coverage of query (297 bits)
GSHRC_BRARP / O04955 Glutathione reductase, cytosolic; GR; GRase; EC 1.8.1.7 from Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis) (see paper)
38% identity, 99% coverage of query (295 bits)
TRXR2_BOVIN / Q9N2I8 Thioredoxin reductase 2, mitochondrial; mt-TR; Thioredoxin reductase TR3; EC 1.8.1.9 from Bos taurus (Bovine) (see paper)
38% identity, 100% coverage of query (290 bits)
G5DA76 thioredoxin-disulfide reductase (EC 1.8.1.9) from Chironomus riparius (see paper)
39% identity, 99% coverage of query (289 bits)
3dh9A / P91938 Crystal structure of drosophila thioredoxin reductase, wild-type
39% identity, 99% coverage of query (288 bits)
TRXR1_DROME / P91938 Thioredoxin reductase 1, mitochondrial; EC 1.8.1.9 from Drosophila melanogaster (Fruit fly) (see 8 papers)
P91938 thioredoxin-disulfide reductase (EC 1.8.1.9) from Drosophila melanogaster (see 3 papers)
39% identity, 99% coverage of query (288 bits)
2nvkX Crystal structure of thioredoxin reductase from drosophila melanogaster
39% identity, 99% coverage of query (288 bits)
TRXR2_MOUSE / Q9JLT4 Thioredoxin reductase 2, mitochondrial; Thioredoxin reductase TR3; EC 1.8.1.9 from Mus musculus (Mouse) (see 3 papers)
Q9JLT4 thioredoxin-disulfide reductase (EC 1.8.1.9) from Mus musculus (see 6 papers)
37% identity, 99% coverage of query (286 bits)
1zdlA / Q9JLT4 Crystal structure of mouse thioredoxin reductase type 2 (see paper)
37% identity, 99% coverage of query (286 bits)
3dgzA Crystal structure of mouse mitochondrial thioredoxin reductase, c- terminal 3-residue truncation
37% identity, 99% coverage of query (286 bits)
W8VZ54 thioredoxin-disulfide reductase (EC 1.8.1.9) from Euglena gracilis (see paper)
40% identity, 99% coverage of query (283 bits)
3o0hB / A0A0H3LWY9 Crystal structure of glutathione reductase from bartonella henselae
38% identity, 99% coverage of query (283 bits)
2wpcA Trypanosoma brucei trypanothione reductase in complex with 3,4- dihydroquinazoline inhibitor (ddd00073357)
37% identity, 100% coverage of query (282 bits)
Q389T8 trypanothione-disulfide reductase (EC 1.8.1.12) from Trypanosoma brucei brucei (see paper)
6btlA / Q389T8 Crystal structure of trypanothione reductase from trypanosoma brucei in complex with inhibitor rd117 1-[2-(piperazin-1-yl)ethyl]-5-{5-[1- (pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1h-indole (see paper)
37% identity, 100% coverage of query (281 bits)
Q7XEM9 glutathione-disulfide reductase (EC 1.8.1.7) from Oryza sativa (see paper)
41% identity, 80% coverage of query (281 bits)
Q962Y6 glutathione-disulfide reductase (EC 1.8.1.7); thioredoxin-disulfide reductase (EC 1.8.1.9) from Schistosoma mansoni (see 2 papers)
37% identity, 99% coverage of query (281 bits)
8a1rA / Q962Y6 Cryo-em structure of thioredoxin glutathione reductase in complex with a non-competitive inhibitor (see paper)
37% identity, 99% coverage of query (281 bits)
8plwA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 33.
37% identity, 99% coverage of query (281 bits)
6bu7A Crystal structure of trypanothione reductase from trypanosoma brucei in complex with inhibitor rd130 1-[2-(piperidin-4-yl)ethyl]-5-{5-[1- (pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1h-indole
37% identity, 100% coverage of query (281 bits)
2wpfA Trypanosoma brucei trypanothione reductase in complex with 3,4- dihydroquinazoline inhibitor (ddd00085762)
37% identity, 100% coverage of query (281 bits)
2wpeA Trypanosoma brucei trypanothione reductase in complex with 3,4- dihydroquinazoline inhibitor (ddd00073359)
37% identity, 100% coverage of query (281 bits)
2wp6A Trypanosoma brucei trypanothione reductase in complex with 3,4- dihydroquinazoline inhibitor (ddd00071494)
37% identity, 100% coverage of query (281 bits)
2wowA Trypanosoma brucei trypanothione reductase with NADP and trypanothione bound
37% identity, 100% coverage of query (281 bits)
7nvpAAA N(1),N(8)-bis(glutathionyl)spermidine reductase
37% identity, 100% coverage of query (281 bits)
6rb5A Trypanothione reductase in complex with 4-(((3-(8-(2-((1r,2s,5r)-6,6- dimethylbicyclo[3.1.1]heptan-2-yl)ethyl)-4-oxo-1-phenyl-1,3,8- triazaspiro[4.5]decan-3-yl)propyl)(methyl)amino)methyl)-4- hydroxypiperidine-1-carboximidamide
37% identity, 100% coverage of query (281 bits)
6rtmA Thioredoxin glutathione reductase from schistosoma mansoni in complex with 1-[(dimethylamino)methyl]-2-naphthol at 2 hour of soaking
37% identity, 99% coverage of query (281 bits)
2wp5A Trypanosoma brucei trypanothione reductase in complex with 3,4- dihydroquinazoline inhibitor (ddd00065414)
37% identity, 100% coverage of query (281 bits)
8plvA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 32.
38% identity, 99% coverage of query (281 bits)
8pl1A Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 2.
37% identity, 99% coverage of query (281 bits)
8plyB Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 35.
37% identity, 99% coverage of query (281 bits)
8plxA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 34.
37% identity, 99% coverage of query (281 bits)
8pltA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 30.
37% identity, 99% coverage of query (281 bits)
8plsA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 29.
37% identity, 99% coverage of query (281 bits)
8plrA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 28.
37% identity, 99% coverage of query (281 bits)
8plqB Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 27.
37% identity, 99% coverage of query (281 bits)
8plpA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 26.
37% identity, 99% coverage of query (281 bits)
8plnA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 24.
37% identity, 99% coverage of query (281 bits)
8pljA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 20.
37% identity, 99% coverage of query (281 bits)
8pleA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 15.
37% identity, 99% coverage of query (281 bits)
8pldA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 14.
37% identity, 99% coverage of query (281 bits)
8plcA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 13.
37% identity, 99% coverage of query (281 bits)
8plbA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 12.
37% identity, 99% coverage of query (281 bits)
8plaA Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 11.
37% identity, 99% coverage of query (281 bits)
8pl9A Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 10.
37% identity, 99% coverage of query (281 bits)
8pl8A Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 9.
37% identity, 99% coverage of query (281 bits)
8pl7A Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 8.
37% identity, 99% coverage of query (281 bits)
8pl6A Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 7.
37% identity, 99% coverage of query (281 bits)
8pl5A Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 6.
37% identity, 99% coverage of query (281 bits)
8pl4A Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 5.
37% identity, 99% coverage of query (281 bits)
8pl3A Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 4.
37% identity, 99% coverage of query (281 bits)
8pl2B Thioredoxin glutathione reductase of schistosoma mansoni fragment screen hit 3.
37% identity, 99% coverage of query (281 bits)
8pddA Thioredoxin glutathione reductase of schistosoma mansoni at 1.25a resolution.
37% identity, 99% coverage of query (281 bits)
Build an alignment for 5211244 and 100 homologs with ≥ 30% identity
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Lawrence Berkeley National Laboratory