Sites on a Tree

 

Searching for up to 100 curated homologs for 6936996 Sama_1170 electron transfer flavoprotein, alpha subunit (RefSeq) (307 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ETFA_HUMAN / P13804 Electron transfer flavoprotein subunit alpha, mitochondrial; Alpha-ETF from Homo sapiens (Human) (see 9 papers)
    59% identity, 100% coverage of query (340 bits)

2a1uA / P13804 Crystal structure of the human etf e165betaa mutant (see paper)
    59% identity, 100% coverage of query (340 bits)

ETFA_MOUSE / Q99LC5 Electron transfer flavoprotein subunit alpha, mitochondrial; Alpha-ETF from Mus musculus (Mouse) (see paper)
    58% identity, 100% coverage of query (332 bits)

ETFA_RAT / P13803 Electron transfer flavoprotein subunit alpha, mitochondrial; Alpha-ETF from Rattus norvegicus (Rat) (see paper)
    58% identity, 100% coverage of query (325 bits)

1efpA / P38974 Electron transfer flavoprotein (etf) from paracoccus denitrificans (see paper)
    59% identity, 98% coverage of query (314 bits)

ETFA_ARATH / Q9C6I6 Electron transfer flavoprotein subunit alpha, mitochondrial; Alpha-ETF from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    50% identity, 100% coverage of query (301 bits)

ETFA_YEAST / Q12480 Probable electron transfer flavoprotein subunit alpha, mitochondrial; Alpha-ETF; Altered inheritance rate of mitochondria protein 45 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    49% identity, 85% coverage of query (250 bits)

ETFA_SYNWW / Q0AZ33 Electron transfer flavoprotein subunit alpha from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) (see 2 papers)
    40% identity, 99% coverage of query (196 bits)

CARE_ACEWD / H6LGM8 Caffeyl-CoA reductase-Etf complex subunit CarE; Electron transfer flavoprotein large subunit; ETFLS; Electron transfer flavoprotein subunit alpha; Alpha-ETF; EC 1.3.1.108 from Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) (see paper)
H6LGM8 caffeoyl-CoA reductase (subunit 1/3) (EC 1.3.1.108) from Acetobacterium woodii (see paper)
    38% identity, 92% coverage of query (177 bits)

6fahE / H6LGM8 Molecular basis of the flavin-based electron-bifurcating caffeyl-coa reductase reaction (see paper)
    38% identity, 92% coverage of query (177 bits)

D2RIQ3 butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin) (subunit 2/3) (EC 1.3.1.109); short-chain acyl-CoA dehydrogenase (EC 1.3.8.1) from Acidaminococcus fermentans (see paper)
    37% identity, 80% coverage of query (164 bits)

4kpuA / D2RIQ3 Electron transferring flavoprotein of acidaminococcus fermentans: towards a mechanism of flavin-based electron bifurcation (see paper)
    37% identity, 80% coverage of query (164 bits)

Q18AQ5 butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin) (subunit 1/3) (EC 1.3.1.109) from Clostridioides difficile (see paper)
    36% identity, 99% coverage of query (160 bits)

5ol2A / A0A125V455 The electron transferring flavoprotein/butyryl-coa dehydrogenase complex from clostridium difficile (see paper)
    36% identity, 99% coverage of query (160 bits)

5ow0A / Q39VG4 Crystal structure of an electron transfer flavoprotein from geobacter metallireducens (see paper)
    41% identity, 78% coverage of query (158 bits)

acrA / G3KIM6 electron-transferring flavoprotein α subunit from Anaerotignum propionicum (see paper)
ETFA_ANAPI / G3KIM6 Acryloyl-CoA reductase electron transfer subunit beta; Electron transfer flavoprotein large subunit; ETFLS; Electron transfer flavoprotein subunit beta; Beta-ETF from Anaerotignum propionicum (Clostridium propionicum) (see paper)
G3KIM6 acrylyl-CoA reductase (NADH) (EC 1.3.1.95) from Anaerotignum propionicum (see paper)
    33% identity, 99% coverage of query (148 bits)

LCTC_ACEWD / H6LBB1 Lactate dehydrogenase (NAD(+),ferredoxin) subunit LctC; Electron transfer flavoprotein large subunit; Electron transfer flavoprotein subunit alpha; EtfA; Lactate dehydrogenase-Etf complex subunit LctC; EC 1.1.1.436 from Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) (see paper)
H6LBB1 lactate dehydrogenase (NAD+, ferredoxin) (subunit 2/3) (EC 1.3.1.110) from Acetobacterium woodii (see paper)
    32% identity, 99% coverage of query (142 bits)

7qh2A / H6LBB1 Cryo-em structure of ldh-etfab complex from acetobacterium woodii (see paper)
    32% identity, 99% coverage of query (141 bits)

7koeB / R4P3F4 Electron bifurcating flavoprotein fix/etfabcx (see paper)
    34% identity, 98% coverage of query (126 bits)

YdiR / b1698 putative electron transfer flavoprotein subunit YdiR from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    31% identity, 77% coverage of query (97.4 bits)

Build an alignment

Build an alignment for 6936996 and 20 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory