Searching for up to 100 curated homologs for 6937359 FitnessBrowser__SB2B:6937359 (515 a.a.)
Found high-coverage hits (≥70%) to 90 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
aldH / AAA89078.1 fatty aldehyde dehydrogenase from Vibrio harveyi (see paper)
47% identity, 96% coverage of query (418 bits)
1eyyA / Q56694 Crystal structure of the NADP+ dependent aldehyde dehydrogenase from vibrio harveyi. (see paper)
47% identity, 95% coverage of query (416 bits)
lhpG / Q88NF5 α-ketoglutaric semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
45% identity, 96% coverage of query (411 bits)
Ga0059261_1896 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Sphingomonas koreensis DSMZ 15582
45% identity, 98% coverage of query (402 bits)
ACIAD0131 / Q6FFQ0 α-ketoglutarate semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
KGSDH_ACIAD / Q6FFQ0 Alpha-ketoglutaric semialdehyde dehydrogenase; alphaKGSA dehydrogenase; 2,5-dioxovalerate dehydrogenase; EC 1.2.1.26 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ0 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Acinetobacter baylyi (see paper)
45% identity, 91% coverage of query (396 bits)
PS417_11015 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas simiae WCS417
42% identity, 98% coverage of query (380 bits)
kgsD / Q9I1Q0 2-ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
44% identity, 98% coverage of query (379 bits)
KGSD2_AZOBR / Q08IC0 Alpha-ketoglutaric semialdehyde dehydrogenase 2; alphaKGSA dehydrogenase 2; 2,5-dioxovalerate dehydrogenase 2; KGSADH-II; EC 1.2.1.26 from Azospirillum brasilense (see paper)
Q08IC0 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see paper)
43% identity, 98% coverage of query (379 bits)
KGSD3_AZOBR / Q08IB7 Alpha-ketoglutaric semialdehyde dehydrogenase 3; alphaKGSA dehydrogenase 3; 2,5-dioxovalerate dehydrogenase 3; KGSADH-III; EC 1.2.1.26 from Azospirillum brasilense (see paper)
Q08IB7 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see paper)
44% identity, 94% coverage of query (375 bits)
Q88GW5 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Pseudomonas putida (see paper)
43% identity, 99% coverage of query (375 bits)
Pf6N2E2_612 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas fluorescens FW300-N2E2
43% identity, 98% coverage of query (372 bits)
HSERO_RS00735 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Herbaspirillum seropedicae SmR1
42% identity, 98% coverage of query (367 bits)
Build an alignment for 6937359 and 12 homologs with ≥ 30% identity
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SLAD_PSEPU / P0DOV9 3-sulfolactaldehyde dehydrogenase; SLA dehydrogenase; EC 1.2.1.97 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
28% identity, 78% coverage of query (103 bits)
3ty7B / Q99SD6 Crystal structure of aldehyde dehydrogenase family protein from staphylococcus aureus
25% identity, 82% coverage of query (100 bits)
B0JFD4 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Lucilia cuprina (see paper)
26% identity, 79% coverage of query (99.4 bits)
PS417_04200 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas simiae WCS417
27% identity, 91% coverage of query (96.3 bits)
Ac3H11_612 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Acidovorax sp. GW101-3H11
27% identity, 81% coverage of query (95.9 bits)
chnE / Q9R2F4 6-oxohexanoate dehydrogenase (EC 1.2.1.63) from Acinetobacter johnsonii (see 2 papers)
27% identity, 76% coverage of query (95.5 bits)
5ur2B / Q6MNK1 Crystal structure of proline utilization a (puta) from bdellovibrio bacteriovorus inactivated by n-propargylglycine (see paper)
25% identity, 92% coverage of query (92.0 bits)
PfGW456L13_1974 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) from Pseudomonas fluorescens GW456-L13
27% identity, 87% coverage of query (90.9 bits)
SSDH2_SCHPO / Q9UTM8 Putative succinate-semialdehyde dehydrogenase C139.05 [NADP(+)]; SSDH; EC 1.2.1.16 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
25% identity, 78% coverage of query (90.9 bits)
Pf1N1B4_1109 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas fluorescens FW300-N1B4
26% identity, 91% coverage of query (90.9 bits)
4neaA / A0A0H2X0S3 1.90 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) from staphylococcus aureus in complex with NAD+ and bme-free cys289 (see paper)
24% identity, 82% coverage of query (90.5 bits)
Q9L4P8 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Staphylococcus aureus (see paper)
24% identity, 82% coverage of query (90.5 bits)
tsaD / P94682 TsaD (EC 1.2.1.62) from Comamonas testosteroni (see paper)
TSAD1_COMTE / P94682 4-(hydroxymethyl)benzenesulfonate dehydrogenase TsaD1; Toluenesulfonate aldehyde dehydrogenase TsaD; EC 1.1.1.257 from Comamonas testosteroni (Pseudomonas testosteroni) (see 2 papers)
25% identity, 95% coverage of query (90.5 bits)
5gtkA NAD+ complex structure of aldehyde dehydrogenase from bacillus cereus
26% identity, 76% coverage of query (90.1 bits)
5gtlA NADPH complex structure of aldehyde dehydrogenase from bacillus cereus
26% identity, 76% coverage of query (90.1 bits)
KGSDH_BACSU / P42236 Alpha-ketoglutaric semialdehyde dehydrogenase; alphaKGSA dehydrogenase; 2,5-dioxovalerate dehydrogenase; EC 1.2.1.26 from Bacillus subtilis (strain 168) (see 2 papers)
26% identity, 94% coverage of query (88.6 bits)
ALDH5_BACSU / O06478 Benzaldehyde dehydrogenase YfmT; Vanillin dehydrogenase; EC 1.2.1.28; EC 1.2.1.67 from Bacillus subtilis (strain 168) (see 2 papers)
26% identity, 87% coverage of query (87.8 bits)
GABD_BACSU / P94428 Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis (strain 168) (see 3 papers)
P94428 succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) from Bacillus subtilis (see paper)
26% identity, 77% coverage of query (85.5 bits)
SM_b20891 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Sinorhizobium meliloti 1021
27% identity, 81% coverage of query (84.7 bits)
4u3wA / B4EFS9 X-ray crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase from burkholderia cenocepacia
25% identity, 81% coverage of query (83.2 bits)
GADH_PICTO / Q6L285 D-glyceraldehyde dehydrogenase (NADP(+)); GADH; Glyceraldehyde DH; EC 1.2.1.89 from Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3) (see paper)
Q6L285 D-glyceraldehyde dehydrogenase (NADP+) (EC 1.2.1.89) from Picrophilus torridus (see paper)
22% identity, 78% coverage of query (82.8 bits)
TGNE_ACIAD / Q6F9G0 Succinate semialdehyde dehydrogenase; SSA dehydrogenase; EC 1.2.1.24 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
25% identity, 78% coverage of query (81.6 bits)
ALDH_DAVTA / P40108 Aldehyde dehydrogenase; ALDDH; ALDH; Allergen Cla h 3; Allergen Cla h III; Allergen Cla h 10; EC 1.2.1.3 from Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum) (see paper)
24% identity, 93% coverage of query (81.6 bits)
padA / CAA66106.1 phenylacetaldehyde dehydrogenase from Escherichia coli (see paper)
26% identity, 79% coverage of query (81.6 bits)
cmpC / CAB06615.1 2-hydroxymuconic semialdehyde dehydrogenase from Sphingomonas sp (see 2 papers)
25% identity, 78% coverage of query (80.1 bits)
4npiA 1.94 angstroms x-ray crystal structure of NAD- and intermediate- bound alpha-aminomuconate-epsilon-semialdehyde dehydrogenase from pseudomonas fluorescens
24% identity, 79% coverage of query (79.7 bits)
4i2rA 2.15 angstroms x-ray crystal structure of NAD- and alternative substrate-bound 2-aminomuconate 6-semialdehyde dehydrogenase from pseudomonas fluorescens
24% identity, 79% coverage of query (79.7 bits)
4i25A 2.00 angstroms x-ray crystal structure of NAD- and substrate-bound 2- aminomuconate 6-semialdehyde dehydrogenase from pseudomonas fluorescens
24% identity, 79% coverage of query (79.7 bits)
5x5uA Crystal structure of alpha-ketoglutarate-semialdehyde dehydrogenase (kgsadh) complexed with NAD
25% identity, 89% coverage of query (79.0 bits)
5x5tA / Q1JUP4 Crystal structure of alpha-ketoglutarate semialdehyde dehydrogenase (kgsadh) from azospirillum brasilense (see paper)
25% identity, 89% coverage of query (79.0 bits)
5kj5B / Q83V33 Crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase n169d in complex with NAD+ (see paper)
23% identity, 79% coverage of query (78.2 bits)
5kllA Crystal structure of 2-hydroxymuconate-6-semialdehyde derived tautomeric intermediate in 2-aminomuconate 6-semialdehyde dehydrogenase n169d
23% identity, 79% coverage of query (77.8 bits)
4ou2A A 2.15 angstroms x-ray crystal structure of e268a 2-aminomuconate 6- semialdehyde dehydrogenase catalytic intermediate from pseudomonas fluorescens
23% identity, 79% coverage of query (77.0 bits)
2eiwA Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from thermus thermophilus with bound l-proline
25% identity, 87% coverage of query (75.9 bits)
2j5nA 1-pyrroline-5-carboxylate dehydrogenase from thermus thermophirus with bound inhibitor glycine and NAD.
25% identity, 87% coverage of query (74.3 bits)
2ej6A Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from thermus thermophilus with bound d-proline
25% identity, 87% coverage of query (74.3 bits)
2eitA Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from thermus thermophilus with bound l-alanine and NAD
25% identity, 87% coverage of query (74.3 bits)
2eiiA Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from thermus thermophilus with bound l-valine and NAD.
25% identity, 87% coverage of query (74.3 bits)
2ehuA Crystal analysis of 1-pyrroline-5-carboxylate dehydrogenase from thermus with bound NAD and inhibitor l-serine
25% identity, 87% coverage of query (74.3 bits)
2ehqA Crystal analysis of 1-pyrroline-5-carboxylate dehydrogenase from thermus with bound NADP
25% identity, 87% coverage of query (74.3 bits)
2bhqA Crystal analysis of 1-pyrroline-5-carboxylate dehydrogenase from thermus with bound product glutamate.
25% identity, 87% coverage of query (74.3 bits)
2bhpA / Q5SI02 Crystal analysis of 1-pyrroline-5-carboxylate dehydrogenase from thermus with bound NAD. (see paper)
25% identity, 87% coverage of query (74.3 bits)
ALDH8A1 / Q9H2A2 aminomuconate-semialdehyde dehydrogenase (EC 1.2.1.32) from Homo sapiens (see 2 papers)
AL8A1_HUMAN / Q9H2A2 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase 12; Aldehyde dehydrogenase family 8 member A1; EC 1.2.1.32 from Homo sapiens (Human) (see 2 papers)
Q9H2A2 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3); aminomuconate-semialdehyde dehydrogenase (EC 1.2.1.32) from Homo sapiens (see 2 papers)
24% identity, 81% coverage of query (73.2 bits)
4o6rA / B4EJX1 Crystal structure of a putative aldehyde dehydrogenase from burkholderia cenocepacia
26% identity, 75% coverage of query (67.4 bits)
2opxA Crystal structure of lactaldehyde dehydrogenase from escherichia coli
24% identity, 81% coverage of query (66.6 bits)
2impA Crystal structure of lactaldehyde dehydrogenase from e. Coli: the ternary complex with lactate (occupancy 0.5) and nadh. Crystals soaked with (l)-lactate.
24% identity, 81% coverage of query (65.9 bits)
2iluA / P25553 Crystal structure of lactaldehyde dehydrogenase from e. Coli: the binary complex with NADPH (see paper)
24% identity, 81% coverage of query (65.9 bits)
Ald / b1415 aldehyde dehydrogenase A (EC 1.2.1.22; EC 1.2.1.21) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
aldA / P25553 aldehyde dehydrogenase A (EC 1.2.1.22; EC 1.2.1.21) from Escherichia coli (strain K12) (see 19 papers)
ALDA_ECOLI / P25553 Lactaldehyde dehydrogenase; Aldehyde dehydrogenase A; Glycolaldehyde dehydrogenase; EC 1.2.1.22; EC 1.2.1.21 from Escherichia coli (strain K12) (see 8 papers)
P25553 lactaldehyde dehydrogenase (EC 1.2.1.22); D-glyceraldehyde dehydrogenase (NADP+) (EC 1.2.1.89) from Escherichia coli (see 2 papers)
24% identity, 81% coverage of query (65.5 bits)
5tjrD X-ray crystal structure of a methylmalonate semialdehyde dehydrogenase from pseudomonas sp. Aac (see paper)
24% identity, 76% coverage of query (65.5 bits)
4pxlA / Q8S532 Structure of zm aldh2-3 (rf2c) in complex with NAD (see paper)
24% identity, 84% coverage of query (63.2 bits)
4jz6A / Q1XGL7 Crystal structure of a salicylaldehyde dehydrogenase from pseudomonas putida g7 complexed with salicylaldehyde (see paper)
22% identity, 85% coverage of query (62.0 bits)
YiaX / b3588 aldehyde dehydrogenase B (EC 1.2.1.4) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
aldB / P37685 aldehyde dehydrogenase B (EC 1.2.1.4) from Escherichia coli (strain K12) (see 7 papers)
ALDB_ECOLI / P37685 Aldehyde dehydrogenase B; Acetaldehyde dehydrogenase; EC 1.2.1.4 from Escherichia coli (strain K12) (see 2 papers)
aldB / GB|AAC76612.2 aldehyde dehydrogenase B; EC 1.2.1.- from Escherichia coli K12 (see 5 papers)
aldB / AAC36939.1 aldehyde dehydrogenase B from Escherichia coli (see paper)
23% identity, 93% coverage of query (61.6 bits)
3hazA / Q89E26 Crystal structure of bifunctional proline utilization a (puta) protein (see paper)
24% identity, 78% coverage of query (61.2 bits)
ALD6 / P54115 magnesium-activated aldehyde dehydrogenase, cytosolic (EC 1.2.1.4) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
ALDH6_YEAST / P54115 Magnesium-activated aldehyde dehydrogenase, cytosolic; Mg(2+)-activated acetaldehyde dehydrogenase; Mg(2+)-ACDH; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P54115 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3); aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Saccharomyces cerevisiae (see 2 papers)
23% identity, 86% coverage of query (60.1 bits)
4i9bA / Q56R04 Structure of aminoaldehyde dehydrogenase 1 from solanum lycopersium (slamadh1) with a thiohemiacetal intermediate (see paper)
24% identity, 87% coverage of query (60.1 bits)
AADH1_SOLLC / Q56R04 Aminoaldehyde dehydrogenase 1; SlAMADH1; 4-trimethylammoniobutyraldehyde dehydrogenase AMADH1; Aminobutyraldehyde dehydrogenase AMADH1; Betaine aldehyde dehydrogenase AMADH1; Gamma-guanidinobutyraldehyde dehydrogenase AMADH1; EC 1.2.1.-; EC 1.2.1.47; EC 1.2.1.19; EC 1.2.1.8; EC 1.2.1.54 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
24% identity, 87% coverage of query (59.7 bits)
ALDH1_ELEED / Q28399 Aldehyde dehydrogenase, cytosolic 1; ALDH class 1; ETA-crystallin; EC 1.2.1.3 from Elephantulus edwardii (Cape long-eared elephant shrew) (see paper)
Q28399 retinal dehydrogenase (EC 1.2.1.36) from Elephantulus edwardii (see paper)
23% identity, 86% coverage of query (59.3 bits)
1o9jA / Q28399 The x-ray crystal structure of eta-crystallin (see paper)
23% identity, 86% coverage of query (58.9 bits)
6bsnA Structure of proline utilization a (puta) with proline bound in remote sites
24% identity, 78% coverage of query (58.2 bits)
4itbA / B1XMM6 Structure of bacterial enzyme in complex with cofactor and substrate (see paper)
25% identity, 77% coverage of query (56.2 bits)
6rtsA / O85725 Piperideine-6-carboxylate dehydrogenase from streptomyces clavuligerus complexed with NAD+ (see paper)
25% identity, 78% coverage of query (55.5 bits)
6rttA Piperideine-6-carboxylate dehydrogenase from streptomyces clavuligerus complexed with picolinic acid
25% identity, 78% coverage of query (55.5 bits)
1uxuA Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (gapn) from thermoproteus tenax
25% identity, 80% coverage of query (53.9 bits)
1uxtA Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (gapn) from thermoproteus tenax
25% identity, 80% coverage of query (53.9 bits)
1uxrA Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (gapn) from thermoproteus tenax
25% identity, 80% coverage of query (53.9 bits)
1uxqA Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (gapn) from thermoproteus tenax
25% identity, 80% coverage of query (53.9 bits)
1uxnA Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (gapn) from thermoproteus tenax
25% identity, 80% coverage of query (53.9 bits)
5ucdA / Q84DC3 Benzaldehyde dehydrogenase, a class 3 aldehyde dehydrogenase, with bound NADP+ and benzoate adduct (see paper)
24% identity, 71% coverage of query (53.9 bits)
3iwjA / Q93YB2 Crystal structure of aminoaldehyde dehydrogenase 2 from pisum sativum (psamadh2) (see paper)
23% identity, 83% coverage of query (53.1 bits)
GAPN_THETE / O57693 NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; Glyceraldehyde phosphate dehydrogenase (NAD(P)); GAPN; EC 1.2.1.90 from Thermoproteus tenax (see 4 papers)
O57693 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (EC 1.2.1.90) from Thermoproteus tenax (see 4 papers)
25% identity, 80% coverage of query (53.1 bits)
AADH2_PEA / Q93YB2 Aminoaldehyde dehydrogenase 2, peroxisomal; PsAMADH2; Aminobutyraldehyde dehydrogenase AMADH2; Gamma-guanidinobutyraldehyde dehydrogenase AMADH2; EC 1.2.1.-; EC 1.2.1.19; EC 1.2.1.54 from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see 2 papers)
Q93YB2 aminobutyraldehyde dehydrogenase (EC 1.2.1.19) from Pisum sativum (see 2 papers)
23% identity, 83% coverage of query (52.8 bits)
1ky8A / O57693 Crystal structure of the non-phosphorylating glyceraldehyde-3- phosphate dehydrogenase (see paper)
25% identity, 80% coverage of query (52.8 bits)
3vz3A Structural insights into substrate and cofactor selection by sp2771
24% identity, 77% coverage of query (52.4 bits)
6rtuA Piperideine-6-carboxylate dehydrogenase from streptomyces clavuligerus complexed with alpha-aminoadipic acid
25% identity, 78% coverage of query (48.9 bits)
6mvtA Structure of a bacterial aldh16 complexed with nadh
24% identity, 82% coverage of query (47.4 bits)
6mvsA Structure of a bacterial aldh16 complexed with NAD
24% identity, 82% coverage of query (47.4 bits)
5iuwA Crystal structure of indole-3-acetaldehyde dehydrogenase in complexed with NAD+ and iaa
24% identity, 85% coverage of query (47.4 bits)
5iuvA / Q88BC5 Crystal structure of indole-3-acetaldehyde dehydrogenase in complexed with NAD+ (see paper)
24% identity, 85% coverage of query (47.4 bits)
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