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Searching for up to 100 curated homologs for 6937577 FitnessBrowser__SB2B:6937577 (364 a.a.)

Found high-coverage hits (≥70%) to 32 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SerC / b0907 phosphoserine/phosphohydroxythreonine aminotransferase (EC 2.6.1.52; EC 2.6.1.17) from Escherichia coli K-12 substr. MG1655 (see 21 papers)
serC / P23721 phosphoserine/phosphohydroxythreonine aminotransferase (EC 2.6.1.52; EC 2.6.1.17) from Escherichia coli (strain K12) (see 21 papers)
SERC_ECOLI / P23721 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Escherichia coli (strain K12) (see 3 papers)
P23721 phosphoserine transaminase (EC 2.6.1.52) from Escherichia coli (see paper)
serC phosphoserine aminotransferase; EC 2.6.1.52 from Escherichia coli K12 (see 9 papers)
    57% identity, 99% coverage of query (418 bits)

1bjoA / P23721 The structure of phosphoserine aminotransferase from e. Coli in complex with alpha-methyl-l-glutamate (see paper)
    57% identity, 99% coverage of query (416 bits)

3qboB Crystal structure of phosphoserine aminotransferase from yersinia pestis co92
    57% identity, 99% coverage of query (409 bits)

7t7jB / A6T700 Crystal structure of phosphoserine aminotransferase from klebsiella pneumoniae subsp. Pneumoniae in complex with pyridoxal phosphate
    56% identity, 99% coverage of query (409 bits)

3qm2B / P55900 2.25 angstrom crystal structure of phosphoserine aminotransferase (serc) from salmonella enterica subsp. Enterica serovar typhimurium
    51% identity, 99% coverage of query (340 bits)

6xdkD / B2FKF0 Crystal structure of phosphoserine aminotransferase (serc) from stenotrophomonas maltophilia k279a
    47% identity, 98% coverage of query (334 bits)

6xdkB Crystal structure of phosphoserine aminotransferase (serc) from stenotrophomonas maltophilia k279a
    47% identity, 98% coverage of query (323 bits)

SERC_SPIOL / P52877 Phosphoserine aminotransferase, chloroplastic; PSAT; Phosphohydroxythreonine aminotransferase; EC 2.6.1.52 from Spinacia oleracea (Spinach) (see paper)
    47% identity, 99% coverage of query (321 bits)

PSAT / Q96255 phosphoserine aminotransferase (EC 2.6.1.52) from Arabidopsis thaliana (see paper)
SERB1_ARATH / Q96255 Phosphoserine aminotransferase 1, chloroplastic; AtPSAT1; Phosphohydroxythreonine aminotransferase; EC 2.6.1.52 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q96255 phosphoserine transaminase (EC 2.6.1.52) from Arabidopsis thaliana (see 3 papers)
    45% identity, 99% coverage of query (315 bits)

SERB2_ARATH / Q9SHP0 Phosphoserine aminotransferase 2, chloroplastic; AtPSAT2; EC 2.6.1.52 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9SHP0 phosphoserine transaminase (EC 2.6.1.52) from Arabidopsis thaliana (see paper)
    45% identity, 99% coverage of query (315 bits)

6czyA / Q96255 Crystal structure of arabidopsis thaliana phosphoserine aminotransferase isoform 1 (atpsat1) in complex with pyridoxamine-5'- phosphate (pmp) (see paper)
    45% identity, 99% coverage of query (315 bits)

6czzA Crystal structure of arabidopsis thaliana phosphoserine aminotransferase isoform 1 (atpsat1) in complex with plp- phosphoserine geminal diamine intermediate
    45% identity, 99% coverage of query (315 bits)

SERC_DROME / Q9VAN0 Probable phosphoserine aminotransferase; PSAT; Phosphohydroxythreonine aminotransferase; EC 2.6.1.52 from Drosophila melanogaster (Fruit fly) (see paper)
    45% identity, 98% coverage of query (306 bits)

1bt4A / Q59196 Phosphoserine aminotransferase from bacillus circulans subsp. Alkalophilus
    44% identity, 97% coverage of query (303 bits)

8a5vE / Q9Y617 Crystal structure of the human phosposerine aminotransferase (psat) (see paper)
    44% identity, 99% coverage of query (303 bits)

PSAT1 / Q9Y617 Phosphoserine aminotransferase (EC 2.6.1.52) from Homo sapiens (see 2 papers)
SERC_HUMAN / Q9Y617 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Homo sapiens (Human) (see 7 papers)
Q9Y617 glycine transaminase (EC 2.6.1.4); phosphoserine transaminase (EC 2.6.1.52) from Homo sapiens (see 5 papers)
    44% identity, 99% coverage of query (303 bits)

SERC_NIACI / Q59196 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Niallia circulans (Bacillus circulans) (see 2 papers)
Q59196 phosphoserine transaminase (EC 2.6.1.52) from Niallia circulans (see paper)
serC / CAA86558.2 phosphoserine aminotransferase from Bacillus circulans subsp. alkalophilus (see paper)
    44% identity, 97% coverage of query (303 bits)

8a5wC Crystal structure of the human phosphoserine aminotransferase (psat) in complex with o-phosphoserine
    44% identity, 99% coverage of query (303 bits)

8a5wA Crystal structure of the human phosphoserine aminotransferase (psat) in complex with o-phosphoserine
    44% identity, 99% coverage of query (303 bits)

8a5vA Crystal structure of the human phosposerine aminotransferase (psat)
    44% identity, 99% coverage of query (303 bits)

Q2F5M8 phosphoserine transaminase (EC 2.6.1.52) from Bombyx mori (see paper)
    46% identity, 100% coverage of query (298 bits)

V9NC98 phosphoserine transaminase (EC 2.6.1.52) from Acanthamoeba castellanii (see paper)
    43% identity, 99% coverage of query (298 bits)

8a5wE Crystal structure of the human phosphoserine aminotransferase (psat) in complex with o-phosphoserine
    44% identity, 99% coverage of query (297 bits)

PSAT1 / A2FXW5 phosphoserine transaminase (EC 2.6.1.52) from Trichomonas vaginalis (strain ATCC PRA-98 / G3) (see paper)
    43% identity, 97% coverage of query (295 bits)

3e77A Human phosphoserine aminotransferase in complex with plp
    44% identity, 96% coverage of query (295 bits)

SERC_ALKAL / Q9RME2 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Alkalihalobacillus alcalophilus (Bacillus alcalophilus) (see 3 papers)
Q9RME2 phosphoserine transaminase (EC 2.6.1.52) from Alkalihalobacillus alcalophilus (see paper)
    41% identity, 98% coverage of query (275 bits)

4azjA / Q9RME2 Structural basis of l-phosphoserine binding to bacillus alcalophilus phosphoserine aminotransferase (see paper)
    41% identity, 98% coverage of query (275 bits)

5yb0B / Q60I38 Crystal structure of wild type phosphoserine aminotransferase (psat) from e. Histolytica (see paper)
    41% identity, 98% coverage of query (273 bits)

1w23B Crystal structure of phosphoserine aminotransferase from bacillus alcalophilus
    41% identity, 98% coverage of query (272 bits)

SERC_YEAST / P33330 Phosphoserine aminotransferase; PSAT; Phosphohydroxythreonine aminotransferase; Serine requiring protein 1; EC 2.6.1.52 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
SERC / AAA20886.1 3-phosphoserine aminotransferase from Saccharomyces cerevisiae (see paper)
    39% identity, 98% coverage of query (259 bits)

Build an alignment

Build an alignment for 6937577 and 30 homologs with ≥ 30% identity

Select sequences

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Additional hits (identity < 30%)

SERC_MYCTU / P9WQ73 Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase; PSAT; EC 2.6.1.52 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WQ73 phosphoserine transaminase (EC 2.6.1.52) from Mycobacterium tuberculosis (see paper)
    23% identity, 86% coverage of query (60.1 bits)

2fyfA / P9WQ73 Structure of a putative phosphoserine aminotransferase from mycobacterium tuberculosis (see paper)
    23% identity, 86% coverage of query (59.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory