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Searching for up to 100 curated homologs for 6937839 FitnessBrowser__SB2B:6937839 (248 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
    74% identity, 98% coverage of query (367 bits)

1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
    74% identity, 98% coverage of query (366 bits)

1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
    74% identity, 98% coverage of query (365 bits)

3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
    72% identity, 98% coverage of query (355 bits)

6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
    72% identity, 98% coverage of query (355 bits)

FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    72% identity, 98% coverage of query (355 bits)

4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
    71% identity, 98% coverage of query (350 bits)

7emgB / A0A0G8B235 Carbonyl reductase variant 4 (r123c/l209p/f183y/v61k) from serratia marcescens complexed with NADP+ (see paper)
    70% identity, 98% coverage of query (345 bits)

Q4AE87 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Pseudomonas sp. (see paper)
fabG / BAE19680.1 3-oxoacyl-(acyl-carrier-protein) reductase from Pseudomonas sp. 61-3 (see paper)
    66% identity, 98% coverage of query (320 bits)

4ag3A Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with NADPH at 1.8a resolution
    65% identity, 98% coverage of query (313 bits)

O54438 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Pseudomonas aeruginosa (see paper)
    65% identity, 98% coverage of query (312 bits)

A5HIF6 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Pseudomonas putida (see paper)
    65% identity, 98% coverage of query (311 bits)

4bo4C / O54438 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with n-(2-methoxyphenyl)-3,4- dihydro-2h-quinoline-1-carboxamide at 2.7a resolution (see paper)
    64% identity, 98% coverage of query (299 bits)

3tzcA Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (fabg)(y155f) from vibrio cholerae (see paper)
    65% identity, 98% coverage of query (298 bits)

4bnzA Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 1-methyl-n-phenylindole- 3-carboxamide at 2.5a resolution
    62% identity, 98% coverage of query (291 bits)

4bnyA Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 4-(2-phenylthieno(3,2-d) pyrimidin-4-yl)morpholine at 1.8a resolution
    62% identity, 98% coverage of query (289 bits)

4bnxA Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 6-(4-(2-chloroanilino)- 1h-quinazolin-2-ylidene)cyclohexa-2, 4-dien-1-one at 2.3a resolution
    62% identity, 98% coverage of query (289 bits)

4bnuA Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 2-phenyl-4-(1,2,4- triazol-4-yl)quinazoline at 2.0a resolution
    62% identity, 98% coverage of query (287 bits)

4bo7A Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with n-(2,3-dihydro-1h-inden- 5-yl)tetrazolo(1,5-b)pyridazin-6-amine at 2.6a resolution
    61% identity, 98% coverage of query (284 bits)

4bo0A Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 1-(4-methoxy-1- methylindazol-3-yl)-3-(2-methoxyphenyl)urea at 2.4a resolution
    61% identity, 98% coverage of query (280 bits)

4bo8A Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 1-(2-amino-4- phenylimidazol-1-yl)-3-(2-fluorophenyl)urea at 2.7a resolution
    61% identity, 98% coverage of query (280 bits)

4bo2A Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 1-(1-ethylbenzimidazol-2- yl)-3-(2-methoxyphenyl)urea at 1.9a resolution
    61% identity, 98% coverage of query (279 bits)

4bo9A Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 5-(2-(furan-2-ylmethoxy) phenyl)-2-phenyltetrazole at 2.9a resolution
    60% identity, 98% coverage of query (277 bits)

4bo5A Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with n-(2-chlorophenyl)-4- pyrrol-1-yl-1,3,5-triazin-2-amine at 2.6a resolution
    61% identity, 98% coverage of query (277 bits)

6t62A / V5VHN7 Crystal structure of acinetobacter baumannii fabg in complex with NADPH at 1.8 a resolution (see paper)
    56% identity, 96% coverage of query (273 bits)

4bo3A Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 2-(3-(trifluoromethyl) anilino)pyridine-3-sulfonamide at 2.5a resolution
    60% identity, 98% coverage of query (273 bits)

6wprA Crystal structure of a putative 3-oxoacyl-acp reductase (fabg) with NADP(h) from acinetobacter baumannii
    56% identity, 96% coverage of query (273 bits)

4bo1A Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with n-(4-chloro-2,5- dimethoxyphenyl)quinoline-8-carboxamide at 2.2a resolution
    60% identity, 98% coverage of query (271 bits)

4bo6A Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 2,3-dihydroindol-1-yl-(2- thiophen-3-yl-1,3-thiazol-4-yl)methanone at 2.8a resolution
    60% identity, 98% coverage of query (268 bits)

4bnvA Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 1-(2-chlorophenyl)-3-(1- methylbenzimidazol-2-yl)urea at 2.5a resolution
    60% identity, 98% coverage of query (267 bits)

4bntB Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 2-(trifluoromethyl)-1h- benzimidazole at 2.3a resolution
    59% identity, 98% coverage of query (265 bits)

Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Staphylococcus aureus (see paper)
    55% identity, 96% coverage of query (262 bits)

FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
    55% identity, 96% coverage of query (261 bits)

FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
    52% identity, 98% coverage of query (261 bits)

3sj7A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
    55% identity, 96% coverage of query (257 bits)

fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
    51% identity, 97% coverage of query (254 bits)

Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
    49% identity, 95% coverage of query (250 bits)

4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
    52% identity, 98% coverage of query (250 bits)

FABG_RICPR / P50941 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Rickettsia prowazekii (strain Madrid E)
P50941 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Rickettsia prowazekii (see paper)
    49% identity, 98% coverage of query (241 bits)

Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Synechococcus elongatus PCC 7942 = FACHB-805 (see paper)
    51% identity, 98% coverage of query (236 bits)

FABG_SYNY3 / P73574 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
    52% identity, 97% coverage of query (232 bits)

4dmmB / Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase from synechococcus elongatus pcc 7942 in complex with NADP
    50% identity, 98% coverage of query (226 bits)

6t65C / V5VHN7 Crsytal structure of acinetobacter baumannii fabg inhibitor complex at 2.35 a resolution (see paper)
    51% identity, 96% coverage of query (226 bits)

1edoA / Q93X62 The x-ray structure of beta-keto acyl carrier protein reductase from brassica napus complexed with NADP+ (see paper)
    49% identity, 95% coverage of query (219 bits)

fabG / D4YGY5 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
    45% identity, 96% coverage of query (218 bits)

AT1G24360 / P33207 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic (EC 1.1.1.100) from Arabidopsis thaliana (see paper)
    48% identity, 95% coverage of query (215 bits)

phaB / Q3IZW0 (R)-3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.36) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see 3 papers)
    46% identity, 96% coverage of query (212 bits)

C7RM91 acetoacetyl-CoA reductase (EC 1.1.1.36) from Candidatus Accumulibacter phosphatis (see 2 papers)
    46% identity, 97% coverage of query (211 bits)

phaB / BAC45231.1 3-keto-acyl-CoA reductase from Bacillus sp. INT005 (see paper)
    47% identity, 98% coverage of query (209 bits)

Q4UN54 acetoacetyl-CoA reductase (EC 1.1.1.36) from Rickettsia felis (see paper)
    46% identity, 96% coverage of query (206 bits)

5ovlA Crystal structure of maba bound to NADP+ from m. Smegmatis
    47% identity, 95% coverage of query (206 bits)

5ovkA / P71534 Crystal structure maba bound to NADPH from m. Smegmatis (see paper)
    47% identity, 95% coverage of query (205 bits)

MABA_MYCS2 / P71534 3-oxoacyl-[acyl-carrier-protein] reductase MabA; 3-ketoacyl-acyl carrier protein reductase; Acetoacetyl-CoA reductase; Beta-ketoacyl-ACP reductase; Beta-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100; EC 1.1.1.36 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
P71534 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Mycolicibacterium smegmatis (see paper)
    47% identity, 95% coverage of query (205 bits)

phbB / P23238 acetoacetyl-CoA reductase subunit (EC 1.1.1.36) from Shinella zoogloeoides (see 2 papers)
PHAB_SHIZO / P23238 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Shinella zoogloeoides (Crabtreella saccharophila) (see paper)
    45% identity, 96% coverage of query (204 bits)

fabG1 / P9WGT2 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) (see paper)
MABA_MYCTU / P9WGT3 3-oxoacyl-[acyl-carrier-protein] reductase MabA; 3-ketoacyl reductase; 3-ketoacyl-acyl carrier protein reductase; Acetoacetyl-CoA reductase; Beta-ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; Mycolic acid biosynthesis A; EC 1.1.1.100; EC 1.1.1.36 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 10 papers)
P9WGT3 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Mycobacterium tuberculosis (see paper)
    45% identity, 95% coverage of query (199 bits)

phbB / AAA90983.1 acetoacetyl CoA reductase from Sinorhizobium meliloti (see 2 papers)
    45% identity, 96% coverage of query (199 bits)

1uznA / P9WGT3 Maba from mycobacterium tuberculosis (see paper)
    45% identity, 95% coverage of query (198 bits)

4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
    44% identity, 96% coverage of query (197 bits)

A0A5P1RES5 acetoacetyl-CoA reductase (subunit 1/2) (EC 1.1.1.36) from Neptunomonas concharum (see paper)
    40% identity, 97% coverage of query (196 bits)

4nbuB Crystal structure of fabg from bacillus sp (see paper)
    43% identity, 97% coverage of query (196 bits)

8jfgA / G2M827 Crystal structure of 3-oxoacyl-acp reductase fabg in complex with NADP+ and 3-keto-octanoyl-acp from helicobacter pylori (see paper)
    44% identity, 98% coverage of query (193 bits)

7caxD / A0A1K1L6W4 Crystal structure of bacterial reductase
    45% identity, 94% coverage of query (190 bits)

5vmlA / Q3JRS9 Crystal structure of acetoacetyl-coa reductase from burkholderia pseudomallei 1710b with bound NADP
    41% identity, 96% coverage of query (190 bits)

4iinA Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from helicobacter pylori 26695 complexed with NAD+
    41% identity, 98% coverage of query (189 bits)

phaB acetoacetyl-CoA reductase PhaB; EC 1.1.1.36 from Acinetobacter sp. RA3849 (see paper)
    42% identity, 96% coverage of query (187 bits)

7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
    41% identity, 99% coverage of query (186 bits)

phbB / D3UAK7 hydroxyvaleryl-CoA reductase (EC 1.1.1.36) from Cupriavidus necator (see 2 papers)
PHAB_CUPNH / P14697 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see 4 papers)
P14697 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); acetoacetyl-CoA reductase (EC 1.1.1.36) from Cupriavidus necator (see 3 papers)
    40% identity, 97% coverage of query (185 bits)

3vzsB / P14697 Crystal structure of phab from ralstonia eutropha in complex with acetoacetyl-coa and NADP (see paper)
    40% identity, 97% coverage of query (184 bits)

BWI76_RS23705 2-deoxy-D-ribonyl-CoA 3-dehydrogenase from Klebsiella michiganensis M5al
    41% identity, 98% coverage of query (182 bits)

8jfiC Crystal structure of 3-oxoacyl-acp reductase fabg in complex with NADP+ and 3-keto-hexanoyl-acp from helicobacter pylori
    42% identity, 98% coverage of query (181 bits)

4cqmF / Q8N4T8 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP (see paper)
    40% identity, 96% coverage of query (180 bits)

CBR4 / Q8N4T8 carbonyl reductase family member 4 (EC 1.1.1.100) from Homo sapiens (see 2 papers)
CBR4_HUMAN / Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; KAR beta subunit; Carbonyl reductase family member 4; CBR4; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; EC 1.1.1.100; EC 1.6.5.10 from Homo sapiens (Human) (see 3 papers)
    40% identity, 96% coverage of query (180 bits)

A0A5P1R8U8 acetoacetyl-CoA reductase (subunit 2/2) (EC 1.1.1.36) from Neptunomonas concharum (see paper)
    43% identity, 97% coverage of query (180 bits)

8jfhD Crystal structure of 3-oxoacyl-acp reductase fabg in complex with NADP+ and 3-keto-octanoyl-acp from helicobacter pylori in an inactive form that priors the acyl substrate delivery
    42% identity, 98% coverage of query (179 bits)

4k6fB / B4EAU4 X-ray crystal structure of a putative acetoacetyl-coa reductase from burkholderia cenocepacia bound to the co-factor NADP
    39% identity, 96% coverage of query (178 bits)

5vt6A / Q3JJT1 Crystal structure of acetoacetyl-coa reductase from burkholderia pseudomallei 1710b complexed with NADP
    39% identity, 96% coverage of query (178 bits)

PHAB_SYNY3 / P73826 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
    42% identity, 98% coverage of query (178 bits)

BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
    40% identity, 95% coverage of query (174 bits)

7pcsB / Q9KJF1 Structure of the heterotetrameric sdr family member bbscd (see paper)
    40% identity, 95% coverage of query (174 bits)

4iiuA / A0A0H2V833 Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from escherichia coli strain cft073 complexed with NADP+ at 2.1 a resolution
    43% identity, 94% coverage of query (174 bits)

7krmC / A0A077GFB1 Putative fabg bound to nadh from acinetobacter baumannii
    42% identity, 97% coverage of query (172 bits)

novJ / Q9L9F8 NovJ from Streptomyces niveus (see paper)
NOVJ_STRNV / Q9L9F8 Short-chain reductase protein NovJ; Novobiocin biosynthesis protein J; EC 1.1.1.- from Streptomyces niveus (Streptomyces spheroides) (see paper)
    42% identity, 94% coverage of query (172 bits)

4nbwA / A6G411 Crystal structure of fabg from plesiocystis pacifica (see paper)
    41% identity, 95% coverage of query (170 bits)

3o03A Quaternary complex structure of gluconate 5-dehydrogenase from streptococcus suis type 2 (see paper)
    40% identity, 98% coverage of query (163 bits)

7x5jC / A0A520KTT2 Acp-dependent oxoacyl reductase
    40% identity, 96% coverage of query (161 bits)

4cqmA Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP
    36% identity, 97% coverage of query (156 bits)

4is3C / P19337 Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (baia2) associated with secondary bile acid synthesis from clostridium scindens vpi12708 in complex with a putative NAD(+)-oh- adduct at 2.0 a resolution
    37% identity, 94% coverage of query (156 bits)

baiA2 / P19337 3α-hydroxysteroid dehydrogenase 2 (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 4 papers)
BAIA2_CLOSV / P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2; 3alpha-hydroxysteroid dehydrogenase 2; 3alpha-HSDH 2; Bile acid-inducible protein BaiA2; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase (EC 1.1.1.395) from [Clostridium] scindens (see paper)
    37% identity, 94% coverage of query (156 bits)

5vp5A / A0QPE7 Crystal structure of a 3-oxoacyl-acyl-carrier protein reductase fabg4 from mycobacterium smegmatis bound to NAD
    42% identity, 96% coverage of query (155 bits)

4cqlI / Q92506 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD (see paper)
    35% identity, 97% coverage of query (155 bits)

3v1uA Crystal structure of a beta-ketoacyl reductase fabg4 from mycobacterium tuberculosis h37rv complexed with NAD+ and hexanoyl-coa at 2.5 angstrom resolution
    40% identity, 96% coverage of query (154 bits)

4fw8A / O53665 Crystal structure of fabg4 complexed with coenzyme nadh (see paper)
    39% identity, 96% coverage of query (153 bits)

3q6iA Crystal structure of fabg4 and coenzyme binary complex
    39% identity, 96% coverage of query (153 bits)

FABG4_MYCTU / I6Y778 3-oxoacyl-[acyl-carrier-protein] reductase [NADH]; Beta-ketoacyl CoA reductase; FASII-like 3-oxoacyl-thioester reductase; HMwFabG; EC 1.1.1.212 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 6 papers)
O53665 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Mycobacterium tuberculosis (see 2 papers)
    39% identity, 96% coverage of query (153 bits)

HSD17B8 / Q92506 estradiol 17β-dehydrogenase 8 (EC 1.1.1.100) from Homo sapiens (see 4 papers)
DHB8_HUMAN / Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; HSD17B8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Protein Ke6; Ke6; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Homo sapiens (Human) (see 5 papers)
Q92506 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Homo sapiens (see paper)
    35% identity, 97% coverage of query (152 bits)

4za2D Crystal structure of pectobacterium carotovorum 2-keto-3-deoxy-d- gluconate dehydrogenase complexed with NAD+ (see paper)
    36% identity, 97% coverage of query (151 bits)

ACT3_STRCO / P16544 Putative ketoacyl reductase; EC 1.3.1.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 2 papers)
    37% identity, 95% coverage of query (147 bits)

2rh4B / P16544 Actinorhodin ketoreductase, actkr, with NADPH and inhibitor emodin (see paper)
    37% identity, 95% coverage of query (147 bits)

1w4zA Structure of actinorhodin polyketide (actiii) reductase
    37% identity, 95% coverage of query (147 bits)

3rwbA Crystal structure of complex of 4pal (4-pyridoxolactone) and pldh (tetrameric pyridoxal 4-dehydrogenase) from mesorhizobium loti
    40% identity, 96% coverage of query (146 bits)

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Build an alignment for 6937839 and 100 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory