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Searching for up to 100 curated homologs for 6937968 FitnessBrowser__SB2B:6937968 (554 a.a.)

Found high-coverage hits (≥70%) to 45 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AsnB / b0674 asparagine synthetase B (EC 6.3.5.4; EC 6.3.1.1; EC 3.5.1.38; EC 3.5.1.2) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
asnB / P22106 asparagine synthetase B (EC 6.3.5.4; EC 6.3.1.1; EC 3.5.1.38) from Escherichia coli (strain K12) (see 17 papers)
ASNB_ECOLI / P22106 Asparagine synthetase B [glutamine-hydrolyzing]; AS-B; EC 6.3.5.4 from Escherichia coli (strain K12) (see 6 papers)
asnB asparagine synthetase B, glutamine-hydrolyzing; EC 6.3.5.4 from Escherichia coli (see paper)
    70% identity, 100% coverage of query (820 bits)

1ct9A / P22106 Crystal structure of asparagine synthetase b from escherichia coli (see paper)
    69% identity, 93% coverage of query (729 bits)

ASNS1_ARATH / P49078 Asparagine synthetase [glutamine-hydrolyzing] 1; Glutamine-dependent asparagine synthetase 1; Protein DARK INDUCIBLE 6; EC 6.3.5.4 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    55% identity, 100% coverage of query (639 bits)

Q9SP19 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Helianthus annuus (see paper)
    56% identity, 100% coverage of query (637 bits)

E7EAQ2 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Pinus pinaster (see paper)
    55% identity, 100% coverage of query (634 bits)

Q6HA26 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Pinus sylvestris (see paper)
    55% identity, 100% coverage of query (633 bits)

F2CQ60 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare subsp. vulgare (see paper)
    55% identity, 100% coverage of query (632 bits)

F2DJ31 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare (see paper)
    55% identity, 100% coverage of query (630 bits)

ASNS2_ORYSJ / Q43011 Asparagine synthetase [glutamine-hydrolyzing] 2; Glutamine-dependent asparagine synthetase 2; EC 6.3.5.4 from Oryza sativa subsp. japonica (Rice) (see paper)
Q43011 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Oryza sativa Japonica Group (see paper)
    55% identity, 100% coverage of query (627 bits)

Q9SP20 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Helianthus annuus (see paper)
    55% identity, 100% coverage of query (625 bits)

A0A1D5VHV8 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Triticum aestivum (see paper)
    55% identity, 100% coverage of query (621 bits)

B3KYI2 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Phaseolus vulgaris (see paper)
    54% identity, 100% coverage of query (621 bits)

A9XS73 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Phaseolus vulgaris (see paper)
    55% identity, 100% coverage of query (621 bits)

D9IXC8 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Pinus pinaster (see paper)
    55% identity, 100% coverage of query (620 bits)

Q93XP9 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare subsp. vulgare (see paper)
    54% identity, 100% coverage of query (620 bits)

A0A1D5YL35 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Triticum aestivum (see paper)
    54% identity, 100% coverage of query (619 bits)

ASNS2_ARATH / Q9LV77 Asparagine synthetase [glutamine-hydrolyzing] 2; Glutamine-dependent asparagine synthetase 2; EC 6.3.5.4 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    55% identity, 99% coverage of query (618 bits)

Q9LKQ9 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Helianthus annuus (see paper)
    54% identity, 100% coverage of query (615 bits)

F2CWZ7 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare subsp. vulgare (see paper)
    55% identity, 100% coverage of query (614 bits)

Q14SM9 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Glycine max (see paper)
    54% identity, 100% coverage of query (613 bits)

Q9SM55 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Phaseolus vulgaris (see paper)
    54% identity, 100% coverage of query (612 bits)

Q10MX3 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Oryza sativa Japonica Group (see paper)
    56% identity, 99% coverage of query (612 bits)

Q84LA5 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare (see paper)
    54% identity, 100% coverage of query (609 bits)

ASNS_SCHPO / P78753 Probable asparagine synthetase [glutamine-hydrolyzing]; Glutamine-dependent asparagine synthetase; EC 6.3.5.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
asn1 / RF|NP_595291.1 asparagine synthetase; EC 6.3.5.4 from Schizosaccharomyces pombe (see 2 papers)
    52% identity, 98% coverage of query (579 bits)

ASN1 asparagine synthetase from Candida albicans (see paper)
    50% identity, 98% coverage of query (542 bits)

ASNS2_YEAST / P49090 Asparagine synthetase [glutamine-hydrolyzing] 2; Glutamine-dependent asparagine synthetase 2; EC 6.3.5.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    51% identity, 93% coverage of query (532 bits)

F2DDF6 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Hordeum vulgare subsp. vulgare (see paper)
    54% identity, 79% coverage of query (484 bits)

ASNS_MOUSE / Q61024 Asparagine synthetase [glutamine-hydrolyzing]; Glutamine-dependent asparagine synthetase; EC 6.3.5.4 from Mus musculus (Mouse) (see paper)
    41% identity, 93% coverage of query (359 bits)

Asns / P49088 asparagine synthetase subunit (EC 6.3.5.4) from Rattus norvegicus (see paper)
    41% identity, 93% coverage of query (353 bits)

ASNS_HUMAN / P08243 Asparagine synthetase [glutamine-hydrolyzing]; Cell cycle control protein TS11; Glutamine-dependent asparagine synthetase; EC 6.3.5.4 from Homo sapiens (Human) (see 2 papers)
P08243 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Homo sapiens (see 4 papers)
    42% identity, 92% coverage of query (349 bits)

6gq3A / P08243 Human asparagine synthetase (asns) in complex with 6-diazo-5-oxo-l- norleucine (don) at 1.85 a resolution (see paper)
    41% identity, 91% coverage of query (331 bits)

Q2L9S5 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) from Bombyx mori (see paper)
    37% identity, 92% coverage of query (308 bits)

asnO / Q92W82 N-acetylglutaminylglutamine amide synthase from Rhizobium meliloti (strain 1021) (see paper)
    30% identity, 82% coverage of query (192 bits)

Build an alignment

Build an alignment for 6937968 and 33 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

oxyD / L8EVF2 malonamoyl-CoA synthetase from Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234) (see 3 papers)
    27% identity, 86% coverage of query (180 bits)

asnB / GB|CAB15032.1 asparagine synthase (glutamine-hydrolysing) 1; EC 6.3.5.4 from Bacillus subtilis (see 4 papers)
    29% identity, 84% coverage of query (178 bits)

asnO / GI|1934835 asparagine synthase (glutamine-hydrolysing) 3; EC 6.3.5.4 from Bacillus subtilis (see 3 papers)
    26% identity, 84% coverage of query (175 bits)

asnH / Q9CDJ2 peptidoglycan asparagine synthase from Lactococcus lactis subsp. lactis (strain IL1403) (see paper)
    30% identity, 70% coverage of query (162 bits)

1mb9A Beta-lactam synthetase complexed with atp
    27% identity, 76% coverage of query (93.6 bits)

1mc1A Beta-lactam synthetase with product (dgpc), amp and ppi
    27% identity, 72% coverage of query (88.2 bits)

1mbzA Beta-lactam synthetase with trapped intermediate
    26% identity, 72% coverage of query (87.4 bits)

bls / P0DJQ7 β-lactam synthetase (EC 6.3.3.4) from Streptomyces clavuligerus (see 2 papers)
    26% identity, 72% coverage of query (86.3 bits)

1jgtB / P0DJQ7 Crystal structure of beta-lactam synthetase (see paper)
    26% identity, 76% coverage of query (85.1 bits)

carA / Q9XB61 carbapenam synthetase subunit (EC 6.3.3.6) from Pectobacterium carotovorum subsp. carotovorum (see 4 papers)
CARA_PECCC / Q9XB61 Carbapenam-3-carboxylate synthase; Carbapenam-3-carboxylate ligase; EC 6.3.3.6 from Pectobacterium carotovorum subsp. carotovorum (Erwinia carotovora subsp. carotovora) (see 4 papers)
Q9XB61 carbapenam-3-carboxylate synthase (EC 6.3.3.6) from Pectobacterium carotovorum (see 3 papers)
    23% identity, 74% coverage of query (82.0 bits)

1q19A / Q9XB61 Carbapenam synthetase (see paper)
    23% identity, 74% coverage of query (81.6 bits)

ASND1_YEAST / Q04489 Asparagine synthetase domain-containing protein YML096W from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    24% identity, 73% coverage of query (74.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory