Searching for up to 100 curated homologs for 6938090 FitnessBrowser__SB2B:6938090 (466 a.a.)
Found high-coverage hits (≥70%) to 25 curated proteins.
Removed hits that are identical to the query, leaving 24
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Shew_1444 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), large permease component from Shewanella loihica PV-4
89% identity, 100% coverage of query (761 bits)
DCTM_PSEAE / Q9HU16 C4-dicarboxylate TRAP transporter large permease protein DctM from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
61% identity, 98% coverage of query (496 bits)
PGA1_c20660 TRAP transporter for fumarate, succinate, L-malate, and 2-oxogulatarate, large permease component from Phaeobacter inhibens BS107
57% identity, 98% coverage of query (456 bits)
DCTM_RHOCA / O07838 C4-dicarboxylate TRAP transporter large permease protein DctM from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (see paper)
TC 2.A.56.1.1 / O07838 DctM, component of Tripartite dicarboxylate:H+ symporter (substrates include: fumarate, D- and L-malate, succinate, succinamide, orotate, iticonate and mesaconate) from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (see 2 papers)
47% identity, 98% coverage of query (384 bits)
DCTMQ_OLEA2 / Q312S1 Isethionate TRAP transporter permease protein DctMQ; TRAP transporter, fused DctMQ subunit from Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20) (Desulfovibrio alaskensis) (see paper)
35% identity, 97% coverage of query (257 bits)
PP_1167 D-glucuronate / D-galacturonate TRAP transporter, large permease component from Pseudomonas putida KT2440
35% identity, 96% coverage of query (223 bits)
TC 2.A.56.1.10 / Q6N8W8 TrapT family, dctM subunit, C4-dicarboxylate transport, component of Transporter for lignin derived aromatic compounds, TarPQM from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
35% identity, 97% coverage of query (218 bits)
SIAT1_HAEIN / P44543 Sialic acid TRAP transporter permease protein SiaT; N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
TC 2.A.56.1.3 / P44543 SiaT aka Sialic acid TRAP transporter permease protein, component of Na+-dependent (smf-driven) sialic acid (N-acetyl neuraminic acid) transporter, SiaTP (Allen et al., 2005; Severi et al., 2005; Johnston et al., 2008). SiaT is also called SiaQM from Haemophilus influenzae (see 2 papers)
30% identity, 97% coverage of query (209 bits)
SIAT2_HAEIF / Q4TVS0 Sialic acid TRAP transporter permease protein SiaT; N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease from Haemophilus influenzae (see paper)
30% identity, 97% coverage of query (209 bits)
Ac3H11_3227 gluconate TRAP transporter, large permease component from Acidovorax sp. GW101-3H11
33% identity, 94% coverage of query (199 bits)
AZOBR_RS15920 Large component of TRAP-type D-gluconate transporter from Azospirillum brasilense Sp245
32% identity, 97% coverage of query (187 bits)
8b01B / Q6LPW1 Cryo-em structure of the tripartite atp-independent periplasmic (trap) transporter siaqm from photobacterium profundum in a nanodisc (see paper)
31% identity, 95% coverage of query (185 bits)
SIAM_VIBCH / Q9KR66 Sialic acid TRAP transporter large permease protein SiaM from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
TC 2.A.56.1.6 / B9TSM9 TRAP dicarboxylate transporter DctM subunit, component of The Na+-dependent sialic acid uptake porter, SiaPQM. SiaQ and SiaM form a 1:1 stoichiometric complex from Vibrio cholerae (see paper)
32% identity, 95% coverage of query (184 bits)
UEHC_RUEPO / Q5LUA9 Ectoine/5-hydroxyectoine TRAP transporter large permease protein UehC; Uptake of ectoine and hydroxyectoine protein C from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
32% identity, 97% coverage of query (182 bits)
TC 2.A.56.1.7 / Q930W3 Putative uncharacterized protein, component of The malonate uptake transporter, MatPQM. Regulated by the GtrA transcriptional activator (Chen et al. 2010). MatM is fused in a single protein C-terminal to MatA (malonyl-CoA decarboxylase) from Rhizobium meliloti (strain 1021)
31% identity, 86% coverage of query (182 bits)
Psest_2124 D-gluconate TRAP transporter, large permease component from Pseudomonas stutzeri RCH2
31% identity, 97% coverage of query (175 bits)
YiaN / b3578 2,3-diketo-L-gulonate:Na+ symporter - membrane subunit from Escherichia coli K-12 substr. MG1655 (see 2 papers)
yiaN / P37675 2,3-diketo-L-gulonate:Na+ symporter - membrane subunit from Escherichia coli (strain K12) (see paper)
YIAN_ECOLI / P37675 2,3-diketo-L-gulonate TRAP transporter large permease protein YiaN from Escherichia coli (strain K12) (see paper)
TC 2.A.56.1.2 / P37675 YiaN, component of The 2,3-diketo-L-gulonate (2,3-DKG) transporter, YiaMNO [2,3-KDG is a breakdown product of L-ascorbate] from Escherichia coli (see 7 papers)
30% identity, 90% coverage of query (170 bits)
TEAC_HALED / E1VBK3 Ectoine TRAP transporter large permease protein TeaC from Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9) (see paper)
30% identity, 95% coverage of query (165 bits)
Build an alignment for 6938090 and 18 homologs with ≥ 30% identity
Or download the sequences
TC 2.A.56.3.2 / Q9RBQ9 FcbT3, component of Tripartite 4-chlorobenzoate symporter (also binds and may transport 4-bromo-, 4-iodo-, and 4-fluorobenzoate and with a lower affinity, 3-chlorobenzoate, 2-chlorobenzoate, 4-hydroxybenzoate, 3-hydroxybenzoate, and benzoate) (see paper)
29% identity, 95% coverage of query (147 bits)
TC 2.A.56.3.3 / Q8YSQ7 Alr3027 protein, component of The 2-oxo monocarboxylate transporter (Pernil et al., 2010). Transports pyruvate which is inhibited by various 2-ketoacids from Nostoc sp. (strain PCC 7120 / UTEX 2576) (see paper)
31% identity, 79% coverage of query (144 bits)
TC 2.A.56.1.9 / R4JQ65 TRAP transporter DctM subunit, component of The possible disulfide 3,3'-dithiodipropionic acid (DTDP) tripartite transporter, DctMPQ from Advenella mimigardefordensis DPN7
31% identity, 96% coverage of query (141 bits)
TC 2.A.56.3.1 / P74224 GtrB aka SLL1103, component of Tripartite glutamate:Na+ symporter (see paper)
29% identity, 94% coverage of query (137 bits)
TC 2.A.56.3.4 / D5ATK1 TRAP C4-dicarboxylate transport system permease, DctM-2 subunit, component of The 2-ketomonocarboxylate transporter (presented in order of affinity - 2-oxovalerate [highest affinity, KD=0.1 μM], 2-oxoisovalerate, 2-oxobutyrate, 2-oxoisocaproate, 2-oxo-3-methylvalerate, pyruvate [lowest affinity, KD=3 μM]) from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
31% identity, 88% coverage of query (114 bits)
TC 2.A.56.2.1 / O83924 Dicarboxylate transporter (DctM), component of TRAP transporter for a hydrophobic substrate (3-d structure known; tp0958 has 18-20 TMSs) (Deka et al., 2012). The substrate could be a lipoprotein, tp0956 (O83922) which is encoded in the same operon with tp0957 and tp058. This protein differs from all other members of the TRAP-T family in having 19 predicted TMSs with extra TMSs at its N-terminus from Treponema pallidum (strain Nichols) (see paper)
27% identity, 88% coverage of query (111 bits)
Or start over
Lawrence Berkeley National Laboratory