Searching for up to 100 curated homologs for 6939142 FitnessBrowser__SB2B:6939142 (445 a.a.)
Found high-coverage hits (≥70%) to 18 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
UhpC / b3667 inner membrane protein sensing glucose-6-phosphate from Escherichia coli K-12 substr. MG1655 (see 4 papers)
UHPC_ECOLI / P09836 Membrane sensor protein UhpC from Escherichia coli (strain K12) (see 5 papers)
TC 2.A.1.4.4 / P09836 Hexose-P:Pi antiporter regulatory protein; senses external glucose-6-P and transports it with high affinity and low efficiency from Escherichia coli (see 7 papers)
uhpC regulatory protein UhpC from Escherichia coli K12 (see 7 papers)
uhpC / ECOCYC|GLU-UHPC membrane protein regulates uhpT expression from Escherichia coli K12 (see 2 papers)
33% identity, 88% coverage of query (216 bits)
TC 2.A.1.4.6 / Q9Z7N9 Glucose-6-P:Pi antiporter, Hpt (may also transport other organophosphates including C3 organophosphates) from Chlamydia pneumoniae (Chlamydophila pneumoniae) (see 3 papers)
30% identity, 99% coverage of query (204 bits)
A0A0H3JLD7 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Staphylococcus aureus (see paper)
35% identity, 87% coverage of query (192 bits)
Q9HTV5 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Pseudomonas aeruginosa (see paper)
32% identity, 92% coverage of query (190 bits)
GlpT / b2240 sn-glycerol 3-phosphate:phosphate antiporter from Escherichia coli K-12 substr. MG1655 (see 24 papers)
glpT / P08194 sn-glycerol 3-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 48 papers)
TC 2.A.1.4.3 / P08194 Glycerol-P:Pi antiporter (may function by a 'rocker switch' mechanism; Law et al., 2007). The 3-d structure is known (3.3Å resolution) (Huang et al., 2003; Lemieux et al., 2005; Lemieux, 2007) from Escherichia coli (see 7 papers)
32% identity, 92% coverage of query (184 bits)
TC 2.A.1.4.11 / Q9ZE92 Glycerol-3-phosphate:inorganic phosphate antiporter, GlpT from Rickettsia prowazekii (strain Madrid E)
30% identity, 85% coverage of query (157 bits)
Build an alignment for 6939142 and 6 homologs with ≥ 30% identity
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TC 2.A.1.4.2 / P12681 P-glycerate:Pi antiporter, Pgt from Salmonella typhimurium (see 2 papers)
28% identity, 87% coverage of query (148 bits)
UhpT / b3666 hexose-6-phosphate:phosphate antiporter from Escherichia coli K-12 substr. MG1655 (see 12 papers)
uhpT / P0AGC0 hexose-6-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 14 papers)
UHPT_ECOLI / P0AGC0 Hexose-6-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 11 papers)
26% identity, 87% coverage of query (120 bits)
G6PT1_HUMAN / O43826 Glucose-6-phosphate exchanger SLC37A4; Glucose-5-phosphate transporter; Glucose-6-phosphate translocase; Solute carrier family 37 member 4; Transformation-related gene 19 protein; TRG-19 from Homo sapiens (Human) (see 24 papers)
TC 2.A.1.4.5 / O43826 Microsomal (ER/Golgi) glucose-6-P:Pi antiporter (glycogen storage disease (GSD1b and 1c); Gierke''s disease protein) (SLC37A2 in mice, associated with white adipose tissue obesity and expressed at high levels in macrophage) (4 isoforms present in humans (Chen et al., 2008)) from Homo sapiens (Human) (see 23 papers)
SLC37A4 / RF|NP_001458.1 glucose-6-phosphate translocase from Homo sapiens
24% identity, 91% coverage of query (110 bits)
TC 2.A.1.4.10 / O69759 2-phosphonoacetate/2-phosponopropionate uptake porter of 428 aas, PhnB from Pseudomonas fluorescens
25% identity, 86% coverage of query (107 bits)
SPX3_MOUSE / Q3TIT8 Sugar phosphate exchanger 3; Solute carrier family 37 member 3 from Mus musculus (Mouse) (see paper)
26% identity, 74% coverage of query (71.6 bits)
S17A9_RAT / P0DX21 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Rattus norvegicus (Rat) (see 2 papers)
22% identity, 84% coverage of query (56.6 bits)
AO356_28540 D-mannose transporter from Pseudomonas fluorescens FW300-N2C3
26% identity, 80% coverage of query (55.8 bits)
S17A9_MOUSE / Q8VCL5 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Mus musculus (Mouse) (see 5 papers)
23% identity, 84% coverage of query (53.9 bits)
TC 2.A.1.14.14 / Q8FDB7 Probable D-galactarate (glucarate?):H+ symporter, GarP or YhaU from Escherichia coli O6 (see paper)
23% identity, 89% coverage of query (52.4 bits)
GarP / b3127 galactarate/D-glucarate transporter GarP from Escherichia coli K-12 substr. MG1655 (see 6 papers)
garP / P0AA80 galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 5 papers)
GARP_ECOLI / P0AA80 Probable galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 2 papers)
23% identity, 89% coverage of query (52.4 bits)
GudP / b2789 galactarate/D-glucarate transporter GudP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gudP / Q46916 galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 5 papers)
GUDP_ECOLI / Q46916 Probable galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.14.40 / C4ZZU4 Glucarate transporter, GudP. Encoded in an operon with GudD, a glucarate dehydratase from Escherichia coli (strain K12 / MC4100 / BW2952)
22% identity, 79% coverage of query (51.2 bits)
S17A9_HUMAN / Q9BYT1 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Homo sapiens (Human) (see 4 papers)
TC 2.A.1.14.21 / Q9BYT1 The vesicular purine nucleotide (ADP, ATP, GTP) transporter, VNUT or SLC17A9. It is found in synaptic vesicles and chromafin granules (Sawada et al., 2008)) and is associated with disseminated superficial actinic porokeratosis (DSAP), a rare autosomal dominant genodermatosis (Cui et al. 2014). It plays a key role in purinergic signaling through its ability to transport nucleotides using the pmf. It catalyzes Cl--dependent transport activity involving essential arginines in the transmembrane region. Ketoacids inhibit these transporters through modulation of Cl- activation, but Cl- and the arginine residues are not important for ATP binding (Iwai et al. 2019). High expression of SLC17A9 correlates with a poor prognosis for colorectal cancer from Homo sapiens (Human) (see 5 papers)
22% identity, 77% coverage of query (50.1 bits)
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Lawrence Berkeley National Laboratory