Searching for up to 100 curated homologs for 6939481 FitnessBrowser__SB2B:6939481 (284 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.149.1 / F5AT04 ABC-transporter, component of ABC immunity system, TrnFG, protecting the bacteria from the bacteriocin, thuricin CD. TrnF is of 213 aas and 6 TMSs while TrnG is of 285 aas and 0 TMSs from Bacillus thuringiensis
34% identity, 76% coverage of query (144 bits)
MEATP_MYCTU / O86311 Multidrug efflux system ATP-binding protein Rv1218c; EC 7.6.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
38% identity, 79% coverage of query (138 bits)
Build an alignment for 6939481 and 2 homologs with ≥ 30% identity
Or download the sequences
YTRB_BACSU / O34641 ABC transporter ATP-binding protein YtrB from Bacillus subtilis (strain 168) (see paper)
29% identity, 83% coverage of query (122 bits)
TC 3.A.1.124.5 / Q09II0 SboF, component of The salivaricin exporter, SboEFG from Streptococcus salivarius (see paper)
35% identity, 77% coverage of query (118 bits)
YhiG / b3486 ribosome-associated ATPase from Escherichia coli K-12 substr. MG1655 (see 13 papers)
RBBA_ECOLI / P37624 Ribosome-associated ATPase; Ribosomal bound ATPase from Escherichia coli (strain K12) (see 5 papers)
yhiH / RF|YP_026225 uncharacterized ABC transporter ATP-binding protein yhiH from Escherichia coli K12 (see paper)
33% identity, 74% coverage of query (117 bits)
nodI / GB|AAB16898.1 nodulation ATP-binding protein I from Rhizobium sp. N33 (see paper)
34% identity, 76% coverage of query (117 bits)
TC 3.A.1.126.1 / Q8RME1 BerA, component of Exporter of β-exotoxin I, BerAB from Bacillus thuringiensis serovar thuringiensis (see 2 papers)
27% identity, 96% coverage of query (115 bits)
sagG / GI|23305059 ABC transporter, ATP-binding protein SagG from Streptococcus iniae (see paper)
33% identity, 73% coverage of query (114 bits)
TC 3.A.1.132.1 / O30489 GldA, component of The GldAFG putative ABC transporter required for ratchet-type gliding motility; may function in secretion of a macromolecule such as an exopolysaccharide. (Agarwal et al., 1997; Hunnicutt et al., 2002; McBride and Zhu 2013). Soluble GldG homologues (no TMSs) are found in eukaryotes (e.g. intraflagellar protein transporter, IPT52 of Chlamydomonas reinhardtii; XP_001692161) from Cytophaga johnsonae (Flavobacterium johnsoniae) (see paper)
29% identity, 75% coverage of query (113 bits)
TC 3.A.1.142.1 / Q8DNB9 Putative uncharacterized protein ABC-NBD, component of Glycolipid translocase (flippase) Spr1816/Spr1817 (R.Hakenbeck, personal communication) from Streptococcus pneumoniae (strain ATCC BAA-255 / R6) (see paper)
30% identity, 86% coverage of query (112 bits)
TC 3.A.1.132.2 / Q52900 NosF, component of The NosDFY Copper ABC transporter from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
nosF / AAC44025.1 NosF protein from Sinorhizobium meliloti (see paper)
33% identity, 78% coverage of query (112 bits)
TC 3.A.1.124.2 / Q45404 SpaF, component of The 3-component subtilin immunity exporter, SpaEFG from Bacillus subtilis (see paper)
33% identity, 75% coverage of query (111 bits)
LNRL_BACSU / P94440 Linearmycin resistance ATP-binding protein LnrL; EC 7.6.2.- from Bacillus subtilis (strain 168) (see 2 papers)
30% identity, 74% coverage of query (110 bits)
TC 3.A.1.105.4 / Q4VWC9 PltI, component of The pyoluteorin (a chlorinated polyketide) efflux pump, PltHIJKN (see 2 papers)
33% identity, 76% coverage of query (109 bits)
YbhF / b0794 ABC exporter ATP binding subunit YbhF (EC 7.6.2.2) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
ybhF / P0A9U1 ABC exporter ATP binding subunit YbhF (EC 7.6.2.2) from Escherichia coli (strain K12) (see 6 papers)
YBHF_ECOLI / P0A9U1 Probable multidrug ABC transporter ATP-binding protein YbhF from Escherichia coli (strain K12) (see paper)
ybhF / MB|P0A9U1 uncharacterized ABC transporter ATP-binding protein ybhF from Escherichia coli K12 (see paper)
32% identity, 79% coverage of query (107 bits)
TC 3.A.1.105.10 / F1QZ58 AbcG homologue, ABCH1 of 705 aas and 6 TMSs in a C-M arrangement from Danio rerio
29% identity, 82% coverage of query (107 bits)
gaaT / BAH08715.1 putative ABC-transporter ATP-binding protein from Lactobacillus gasseri (see 2 papers)
29% identity, 75% coverage of query (105 bits)
TC 3.A.1.124.6 / Q18BL2 ABC-type transport system,lantibiotic/multidrug-family ATP-binding protein, component of CprABC antimicrobial peptide resistance ABC exporter from Peptoclostridium difficile (strain 630)
30% identity, 75% coverage of query (104 bits)
LSRA_SALTY / Q8ZKQ4 Autoinducer 2 import ATP-binding protein LsrA; AI-2 import ATP-binding protein LsrA; EC 7.6.2.13 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
33% identity, 75% coverage of query (104 bits)
ECSA_BACSU / P55339 ABC-type transporter ATP-binding protein EcsA from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.143.1 / P55339 ABC-type transporter ATP-binding protein EcsA, component of The exoprotein (including α-amylase) secretion system, EcsAB(C) (Leskelä et al., 1999). Also may play roles in sporulation, competence (Leskelä et al., 1996) and transformation using purified DNA (Takeno et al., 2011). An involvement of EcsC in transport is not established, but it is homologous to the C-terminus of the P-type ATPase, 3.A.3.31.2 from Bacillus subtilis (strain 168) (see 3 papers)
30% identity, 76% coverage of query (100 bits)
7o12B / P19844 Abc transporter nosdfy, amppnp-bound in gdn (see paper)
35% identity, 76% coverage of query (98.2 bits)
7o17B Abc transporter nosdfy e154q, atp-bound in lipid nanodisc
34% identity, 76% coverage of query (97.1 bits)
ABC1_MYCTU / O65934 ABC transporter ATP-binding/permease protein Rv1747; EC 7.-.-.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
34% identity, 71% coverage of query (97.1 bits)
6xjhC Pmtcd abc exporter without the basket domain at c2 symmetry
26% identity, 73% coverage of query (91.7 bits)
6xjiC / X5EJW5 Pmtcd abc exporter at c1 symmetry (see paper)
26% identity, 73% coverage of query (90.9 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
33% identity, 76% coverage of query (89.0 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
30% identity, 74% coverage of query (88.6 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
30% identity, 74% coverage of query (88.6 bits)
2olkA Abc protein artp in complex with adp-beta-s
30% identity, 74% coverage of query (88.6 bits)
2oljA Abc protein artp in complex with adp/mg2+
30% identity, 74% coverage of query (88.6 bits)
RbsA / b3749 ribose ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsA / P04983 ribose ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 2 papers)
RBSA_ECOLI / P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.1 / P04983 RbsA aka B3749, component of Ribose porter from Escherichia coli (see 6 papers)
rbsA / GB|AAC76772.1 ribose transport, ATP-binding protein RbsA; EC 3.6.3.17 from Escherichia coli K12 (see 7 papers)
26% identity, 82% coverage of query (88.6 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
32% identity, 76% coverage of query (87.8 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
32% identity, 76% coverage of query (87.8 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
32% identity, 76% coverage of query (87.4 bits)
ABCAD_MOUSE / Q5SSE9 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Mus musculus (Mouse) (see 3 papers)
28% identity, 75% coverage of query (87.4 bits)
ABCA1_MOUSE / P41233 Phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ABC-1; ATP-binding cassette 1; EC 7.6.2.1 from Mus musculus (Mouse) (see 2 papers)
27% identity, 74% coverage of query (87.0 bits)
ABCA1_HUMAN / O95477 Phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ABC-1; ATP-binding cassette 1; Cholesterol efflux regulatory protein; EC 7.6.2.1 from Homo sapiens (Human) (see 34 papers)
TC 3.A.1.211.14 / O95477 cAMP-dependent and sulfonylurea-sensitive anion transporter, ABCA1 of 2261 aas. Key gatekeeper influencing and possibly catalyzing intracellular phospholipid and cholesterol transport from Homo sapiens
27% identity, 74% coverage of query (86.7 bits)
ABCA3_MOUSE / Q8R420 Phospholipid-transporting ATPase ABCA3; ATP-binding cassette sub-family A member 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Mus musculus (Mouse) (see 7 papers)
28% identity, 92% coverage of query (85.9 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
29% identity, 74% coverage of query (85.5 bits)
7tbwA / O95477 The structure of atp-bound abca1 (see paper)
26% identity, 74% coverage of query (85.1 bits)
6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
29% identity, 81% coverage of query (84.3 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
27% identity, 73% coverage of query (84.0 bits)
8ee6A / Q8IZY2 Cryo-em structure of human abca7 in pe/ch nanodiscs (see paper)
29% identity, 75% coverage of query (83.6 bits)
ABCAC_MOUSE / E9Q876 Glucosylceramide transporter ABCA12; ATP-binding cassette sub-family A member 12; EC 7.6.2.1 from Mus musculus (Mouse) (see 9 papers)
28% identity, 71% coverage of query (82.8 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
29% identity, 76% coverage of query (82.8 bits)
8eopA / Q8IZY2 Cryo-em structure of nanodisc reconstituted human abca7 eq mutant in atp bound closed state (see paper)
29% identity, 75% coverage of query (82.4 bits)
FhuC / b0151 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FhuC / P07821 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see paper)
FHUC_ECOLI / P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.3 / P07821 FhuC aka B0151, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 6 papers)
fhuC / GB|BAB96727.2 ferrichrome transport ATP-binding protein FhuC; EC 3.6.3.34 from Escherichia coli K12 (see 8 papers)
31% identity, 73% coverage of query (82.4 bits)
CED7_CAEEL / P34358 ABC transporter ced-7; Cell death protein 7 from Caenorhabditis elegans (see paper)
TC 3.A.1.211.4 / P34358 The aced cell death 7 (ced-7) protein (translocates molecules that mediate adhesion between dying and engulfing embryonic cells during programmed death) from Caenorhabditis elegans (see 4 papers)
ced-7 / RF|NP_001021226.1 ABC transporter ced-7 from Caenorhabditis elegans
29% identity, 74% coverage of query (82.0 bits)
ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
32% identity, 73% coverage of query (82.0 bits)
ABCA3_HUMAN / Q99758 Phospholipid-transporting ATPase ABCA3; ABC-C transporter; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Homo sapiens (Human) (see 18 papers)
TC 3.A.1.211.5 / Q99758 The surfactant-secreting porter, ABCA3 (exports lipids and proteins into lamellar bodies). Fatal surfactant deficiency (FSD) can result from mutations in ABCA3, causing abnormal intracellular localization (type I) or decreased ATP hydrolysis (type II). Other mutations cause pediatric interstitial lung disease (pILD) from Homo sapiens (Human) (see 7 papers)
ABCA3 / RF|NP_001080.2 ATP-binding cassette sub-family A member 3 from Homo sapiens (see paper)
29% identity, 81% coverage of query (81.6 bits)
1ji0A / Q9X0M3 Crystal structure analysis of the abc transporter from thermotoga maritima
30% identity, 74% coverage of query (81.6 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
24% identity, 74% coverage of query (80.9 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
29% identity, 72% coverage of query (80.9 bits)
6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
30% identity, 74% coverage of query (79.7 bits)
6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
30% identity, 74% coverage of query (79.7 bits)
6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
30% identity, 74% coverage of query (79.7 bits)
6b89A E. Coli lptb in complex with adp and novobiocin
30% identity, 74% coverage of query (79.7 bits)
4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
30% identity, 74% coverage of query (79.7 bits)
6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
30% identity, 74% coverage of query (79.7 bits)
1g6hA / Q58663 Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
28% identity, 74% coverage of query (79.0 bits)
6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
29% identity, 74% coverage of query (78.6 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
27% identity, 73% coverage of query (78.2 bits)
1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter
28% identity, 74% coverage of query (77.8 bits)
3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
29% identity, 73% coverage of query (77.4 bits)
ABCA2_HUMAN / Q9BZC7 ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette 2; EC 7.6.2.- from Homo sapiens (Human) (see 10 papers)
29% identity, 72% coverage of query (76.6 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
26% identity, 77% coverage of query (76.6 bits)
7t55A / A3DCU1 Cryo-em structure of pcat1 in the inward-facing wide conformation under atp turnover condition (see paper)
27% identity, 73% coverage of query (76.3 bits)
7lkzA Structure of atp-bound human abca4
26% identity, 83% coverage of query (75.9 bits)
4s0fA Crystal structure of the peptidase-containing abc transporter pcat1 e648q mutant complexed with atpgs in an occluded conformation
26% identity, 73% coverage of query (75.5 bits)
7ahhC Opua inhibited inward-facing, sbd docked
24% identity, 89% coverage of query (75.5 bits)
7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
24% identity, 89% coverage of query (75.5 bits)
7w02A / Q99758 Cryo-em structure of atp-bound abca3 (see paper)
29% identity, 74% coverage of query (74.7 bits)
8f5bA / P78363 Human abca4 structure in complex with amp-pnp
26% identity, 92% coverage of query (74.7 bits)
7ahdC Opua (e190q) occluded
25% identity, 71% coverage of query (74.3 bits)
2pclA / O66646 Crystal structure of abc transporter with complex (aq_297) from aquifex aeolicus vf5
30% identity, 76% coverage of query (74.3 bits)
8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
29% identity, 79% coverage of query (74.3 bits)
ABCA4_HUMAN / P78363 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM proteinv; RmP; Retinal-specific ATP-binding cassette transporter; Stargardt disease protein; EC 7.6.2.1 from Homo sapiens (Human) (see 38 papers)
TC 3.A.1.211.2 / P78363 The retinal-specific ABC transporter (RIM protein, ABCR or ABCA4) (Stargardt's disease protein, involved in retinal/macular degeneration) in the rod outer segment. Changes in the oligomeric state of the nucleotide binding domains of ABCR are coupled to ATP hydrolysis and might represent a signal for the TMDs of ABCR to export the bound substrate (Biswas-Fiss 2006). The ABCA4 porter flips N-retinylidene-phosphatidylethanolamine, a product generated from the photobleaching of rhodopsin, from the lumen to the cytoplasmic side of disc membranes following the photobleaching of rhodopsin, insuring that retinoids do not accumulate in disc membranes (Molday, 2007; Molday et al. 2009; Tsybovsky et al. 2013). It also transports several vitamin A derivatives (Sun, 2011) and phosphatidylethanolamine in the same direction. Mutations, known to cause Stargardt disease, decrease N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine transport activities (Quazi et al. 2012). It functions as an inwardly directed retinoid flippase in the visual cycle from Homo sapiens (Human) (see 28 papers)
26% identity, 77% coverage of query (74.3 bits)
7e7oA / P78363 Cryo-em structure of human abca4 in nrpe-bound state (see paper)
26% identity, 77% coverage of query (73.9 bits)
7lkpA Structure of atp-free human abca4
26% identity, 77% coverage of query (73.9 bits)
5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
29% identity, 79% coverage of query (73.9 bits)
ABCA4_BOVIN / F1MWM0 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM protein; RmP; Retinal-specific ATP-binding cassette transporter; EC 7.6.2.1 from Bos taurus (Bovine) (see 11 papers)
26% identity, 74% coverage of query (73.9 bits)
8i6rB / Q9I6C0 Cryo-em structure of pseudomonas aeruginosa ftse(e163q)x/envc complex with atp in peptidisc (see paper)
27% identity, 70% coverage of query (73.6 bits)
ABCA9_HUMAN / Q8IUA7 ATP-binding cassette sub-family A member 9; EC 7.6.2.- from Homo sapiens (Human) (see paper)
TC 3.A.1.211.16 / Q8IUA7 ATP-binding cassette sub-family A member 9, ABCA9 of 1624 aas. May play a role in monocyte differentiation and lipid homeostasis. Expressed in fetal tissues with highest expression in fetal heart and kidney. Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages from Homo sapiens
27% identity, 74% coverage of query (73.6 bits)
MacB / b0879 ABC-type tripartite efflux pump ATP binding/membrane subunit from Escherichia coli K-12 substr. MG1655 (see 14 papers)
MacB / P75831 ABC-type tripartite efflux pump ATP binding/membrane subunit from Escherichia coli (strain K12) (see 16 papers)
MACB_ECOLI / P75831 Macrolide export ATP-binding/permease protein MacB; EC 7.6.2.- from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.122.1 / P75831 MacB aka B0879, component of Macrolide (14- and 15- but not 16-membered lactone macrolides including erythromycin) exporter, MacAB (formerly YbjYZ). Both MacA and MacB are required for activity (Tikhonova et al., 2007). MacAB functions with TolC to export multiple drugs and heat-stable enterotoxin II (enterotoxin STII) (Yamanaka et al., 2008). The crystal structure of MacA is available (Yum et al., 2009). MacB is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA (Lin et al., 2009). Xu et al. (2009) have reported the crystal structure of the periplasmic region of MacB which they claim resembles the periplasmic domain of RND-type transporters such as AcrB (TC# 2.A.6.2.2). Also exports L-cysteine (Yamada et al., 2006). The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by the MacB transporter from Escherichia coli (see 5 papers)
macB / BAB64542.1 macrolide-specific ABC-type efflux carrier from Escherichia coli (see paper)
29% identity, 73% coverage of query (72.8 bits)
7e7qA / P78363 Cryo-em structure of human abca4 in atp-bound state (see paper)
26% identity, 85% coverage of query (72.8 bits)
8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
29% identity, 79% coverage of query (72.4 bits)
7m1qA / P78363 Human abca4 structure in complex with n-ret-pe (see paper)
22% identity, 92% coverage of query (72.0 bits)
7z15I / P16678 E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
27% identity, 76% coverage of query (71.6 bits)
1g291 / Q9YGA6 Malk (see paper)
27% identity, 73% coverage of query (71.6 bits)
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp
27% identity, 76% coverage of query (71.6 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
28% identity, 73% coverage of query (71.2 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
28% identity, 73% coverage of query (71.2 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
28% identity, 73% coverage of query (71.2 bits)
ABCA6_HUMAN / Q8N139 ATP-binding cassette sub-family A member 6; EC 7.6.2.- from Homo sapiens (Human) (see 3 papers)
TC 3.A.1.211.15 / Q8N139 ATP-binding cassette sub-family A member 6, ABCA6 of 1617 aas. This transporter may play a role in macrophage lipid homeostasis. It is up-regulated during monocyte differentiation into macrophages but down-regulated by cholesterol loading of macrophages from Homo sapiens
23% identity, 73% coverage of query (70.9 bits)
LolD / b1117 lipoprotein release complex - ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 2 papers)
LolD / P75957 lipoprotein release complex - ATP binding subunit from Escherichia coli (strain K12) (see paper)
LOLD_ECOLI / P75957 Lipoprotein-releasing system ATP-binding protein LolD; EC 7.6.2.- from Escherichia coli (strain K12) (see paper)
TC 3.A.1.125.1 / P75957 LolD aka B1117, component of Lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope) (see 1.B.46; Narita et al., 2003; Ito et al., 2006; Watanabe et al., 2007). The structure of ligand-bound LolCDE has been solved (Ito et al., 2006). LolC and LolE each have 4 TMSs (1+3). Unlike most ATP binding cassette transporters mediating the transmembrane flux of substrates, the LolCDE complex catalyzes the extrusion of lipoproteins anchored to the outer leaflet of the inner membrane. The LolCDE complex is unusual in that it can be purified as a liganded form, which is an intermediate of the lipoprotein release reaction (Taniguchi and Tokuda, 2008). LolCDE has been reconstituted from separated subunits from Escherichia coli (see 5 papers)
lolD / GB|BAA35937.2 lipoprotein releasing system, ATP-binding protein; EC 3.6.3.- from Escherichia coli K12 (see 5 papers)
28% identity, 73% coverage of query (70.5 bits)
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation
26% identity, 76% coverage of query (70.5 bits)
7arlD Lolcde in complex with lipoprotein and adp
28% identity, 73% coverage of query (70.5 bits)
7mdyC Lolcde nucleotide-bound
28% identity, 73% coverage of query (70.1 bits)
ETTA_ECOL6 / A0A0H2VFI8 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
29% identity, 71% coverage of query (70.1 bits)
YjjK / b4391 energy-dependent translational throttle protein EttA from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ETTA_ECOLI / P0A9W3 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Escherichia coli (strain K12) (see 2 papers)
CH_004211 ABC transporter, ATP-binding protein YjiK from Escherichia coli K12 (see paper)
29% identity, 71% coverage of query (69.7 bits)
Or start over
Lawrence Berkeley National Laboratory