Sites on a Tree

 

Searching for up to 100 curated homologs for 7023263 FitnessBrowser__ANA3:7023263 (348 a.a.)

Found high-coverage hits (≥70%) to 21 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

NOSF_STUST / P19844 Probable ABC transporter ATP-binding protein NosF from Stutzerimonas stutzeri (Pseudomonas stutzeri) (see 2 papers)
nosF / CAA37716.1 NosF ATPase from Pseudomonas stutzeri (see 13 papers)
    42% identity, 85% coverage of query (199 bits)

7o12B / P19844 Abc transporter nosdfy, amppnp-bound in gdn (see paper)
    42% identity, 85% coverage of query (199 bits)

7o17B Abc transporter nosdfy e154q, atp-bound in lipid nanodisc
    42% identity, 85% coverage of query (198 bits)

TC 3.A.1.132.2 / Q52900 NosF, component of The NosDFY Copper ABC transporter from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
nosF / AAC44025.1 NosF protein from Sinorhizobium meliloti (see paper)
    37% identity, 86% coverage of query (194 bits)

nodI / GB|AAB16898.1 nodulation ATP-binding protein I from Rhizobium sp. N33 (see paper)
    30% identity, 84% coverage of query (134 bits)

TC 3.A.1.132.1 / O30489 GldA, component of The GldAFG putative ABC transporter required for ratchet-type gliding motility; may function in secretion of a macromolecule such as an exopolysaccharide. (Agarwal et al., 1997; Hunnicutt et al., 2002; McBride and Zhu 2013). Soluble GldG homologues (no TMSs) are found in eukaryotes (e.g. intraflagellar protein transporter, IPT52 of Chlamydomonas reinhardtii; XP_001692161) from Cytophaga johnsonae (Flavobacterium johnsoniae) (see paper)
    31% identity, 78% coverage of query (132 bits)

TC 3.A.1.102.1 / P50332 NodI, component of Lipooligosaccharide exporter (nodulation proteins, NodIJ) from Rhizobium galegae (see paper)
    33% identity, 84% coverage of query (130 bits)

Build an alignment

Build an alignment for 7023263 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

ABCA7_MOUSE / Q91V24 ATP-binding cassette sub-family A member 7 from Mus musculus (Mouse) (see 10 papers)
    28% identity, 93% coverage of query (127 bits)

DRRA_STRPE / P32010 Daunorubicin/doxorubicin resistance ATP-binding protein DrrA; EC 7.6.2.- from Streptomyces peucetius (see 2 papers)
P32010 ABC-type xenobiotic transporter (EC 7.6.2.2) from Streptomyces peucetius (see paper)
TC 3.A.1.105.1 / P32010 DrrA, component of Daunorubicin, doxorubicin etc. (multidrug resistance) exporter, DrrAB from Streptomyces peucetius (see 2 papers)
    29% identity, 85% coverage of query (125 bits)

4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
    28% identity, 83% coverage of query (125 bits)

7tbwA / O95477 The structure of atp-bound abca1 (see paper)
    28% identity, 79% coverage of query (119 bits)

8ee6A / Q8IZY2 Cryo-em structure of human abca7 in pe/ch nanodiscs (see paper)
    27% identity, 87% coverage of query (114 bits)

ABCAD_MOUSE / Q5SSE9 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Mus musculus (Mouse) (see 3 papers)
    27% identity, 92% coverage of query (113 bits)

ABCA1_MOUSE / P41233 Phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ABC-1; ATP-binding cassette 1; EC 7.6.2.1 from Mus musculus (Mouse) (see 2 papers)
    25% identity, 77% coverage of query (107 bits)

ABCA9_HUMAN / Q8IUA7 ATP-binding cassette sub-family A member 9; EC 7.6.2.- from Homo sapiens (Human) (see paper)
TC 3.A.1.211.16 / Q8IUA7 ATP-binding cassette sub-family A member 9, ABCA9 of 1624 aas. May play a role in monocyte differentiation and lipid homeostasis. Expressed in fetal tissues with highest expression in fetal heart and kidney. Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages from Homo sapiens
    27% identity, 79% coverage of query (105 bits)

ABCA1_HUMAN / O95477 Phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ABC-1; ATP-binding cassette 1; Cholesterol efflux regulatory protein; EC 7.6.2.1 from Homo sapiens (Human) (see 34 papers)
TC 3.A.1.211.14 / O95477 cAMP-dependent and sulfonylurea-sensitive anion transporter, ABCA1 of 2261 aas. Key gatekeeper influencing and possibly catalyzing intracellular phospholipid and cholesterol transport from Homo sapiens
    25% identity, 77% coverage of query (104 bits)

8f5bA / P78363 Human abca4 structure in complex with amp-pnp
    25% identity, 80% coverage of query (102 bits)

7e7qA / P78363 Cryo-em structure of human abca4 in atp-bound state (see paper)
    24% identity, 80% coverage of query (101 bits)

7lkzA Structure of atp-bound human abca4
    25% identity, 80% coverage of query (100 bits)

CED7_CAEEL / P34358 ABC transporter ced-7; Cell death protein 7 from Caenorhabditis elegans (see paper)
TC 3.A.1.211.4 / P34358 The aced cell death 7 (ced-7) protein (translocates molecules that mediate adhesion between dying and engulfing embryonic cells during programmed death) from Caenorhabditis elegans (see 4 papers)
ced-7 / RF|NP_001021226.1 ABC transporter ced-7 from Caenorhabditis elegans
    25% identity, 88% coverage of query (97.1 bits)

7tbyA / O95477 The structure of human abca1 in nanodisc (see paper)
    24% identity, 77% coverage of query (88.2 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory