Searching for up to 100 curated homologs for 7023736 FitnessBrowser__ANA3:7023736 (270 a.a.)

Found high-coverage hits (≥70%) to 37 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

1drvA Escherichia coli dhpr/acnadh complex
    67% identity, 99% coverage of query (351 bits)

1druA Escherichia coli dhpr/nadh complex
    67% identity, 99% coverage of query (351 bits)

1arzA Escherichia coli dihydrodipicolinate reductase in complex with nadh and 2,6 pyridine dicarboxylate
    67% identity, 99% coverage of query (351 bits)

1arzB Escherichia coli dihydrodipicolinate reductase in complex with nadh and 2,6 pyridine dicarboxylate
    67% identity, 99% coverage of query (351 bits)

1dihA / P04036 Three-dimensional structure of e. Coli dihydrodipicolinate reductase (see paper)
    67% identity, 99% coverage of query (350 bits)

DapB / b0031 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
dapB / P04036 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Escherichia coli (strain K12) (see 17 papers)
DAPB_ECOLI / P04036 4-hydroxy-tetrahydrodipicolinate reductase; HTPA reductase; EC 1.17.1.8 from Escherichia coli (strain K12) (see 6 papers)
dapB / GB|BAB96600.1 dihydrodipicolinate reductase; EC 1.3.1.26 from Escherichia coli K12 (see paper)
    67% identity, 99% coverage of query (350 bits)

1drwA Escherichia coli dhpr/nhdh complex
    67% identity, 99% coverage of query (350 bits)

5tejA / Q8DEM0 Structure of 4-hydroxy-tetrahydrodipicolinate reductase from vibrio vulnificus with 2,5 furan dicarboxylic and nadh (see paper)
    63% identity, 99% coverage of query (347 bits)

5tejB Structure of 4-hydroxy-tetrahydrodipicolinate reductase from vibrio vulnificus with 2,5 furan dicarboxylic and nadh
    63% identity, 99% coverage of query (347 bits)

5temA Structure of 4-hydroxy-tetrahydrodipicolinate reductase from vibrio vulnificus with 2,6 pyridine dicarboxylic and nadh
    63% identity, 98% coverage of query (344 bits)

4ywjA / P38103 Crystal structure of 4-hydroxy-tetrahydrodipicolinate reductase (htpa reductase) from pseudomonas aeruginosa
    60% identity, 98% coverage of query (314 bits)

Q9K1F1 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Neisseria meningitidis (see paper)
    59% identity, 99% coverage of query (300 bits)

3ijpB / Q6G2G3 Crystal structure of dihydrodipicolinate reductase from bartonella henselae at 2.0a resolution (see paper)
    42% identity, 99% coverage of query (213 bits)

Q6G2G3 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Bartonella henselae (see paper)
    42% identity, 99% coverage of query (213 bits)

Q2YJN7 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Brucella abortus (see paper)
    47% identity, 97% coverage of query (213 bits)

3ijpA Crystal structure of dihydrodipicolinate reductase from bartonella henselae at 2.0a resolution
    42% identity, 99% coverage of query (211 bits)

DvMF_0450 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Desulfovibrio vulgaris Miyazaki F
    42% identity, 97% coverage of query (196 bits)

DAPB_THEMA / Q9X1K8 4-hydroxy-tetrahydrodipicolinate reductase; HTPA reductase; EC 1.17.1.8 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    35% identity, 73% coverage of query (141 bits)

1vm6B / Q9X1K8 Crystal structure of dihydrodipicolinate reductase (tm1520) from thermotoga maritima at 2.27 a resolution
    35% identity, 73% coverage of query (140 bits)

Q5HG24 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Staphylococcus aureus (see paper)
    38% identity, 70% coverage of query (123 bits)

5z2eA / A0A3B6UER2 Dipicolinate bound dihydrodipicolinate reductase from paenisporosarcina sp. Tg-14 (see paper)
    30% identity, 97% coverage of query (110 bits)

5z2fA NADPH/pda bound dihydrodipicolinate reductase from paenisporosarcina sp. Tg-14
    30% identity, 97% coverage of query (110 bits)

Q3MFY8 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Trichormus variabilis (see paper)
    31% identity, 97% coverage of query (109 bits)

dapB / P42976 dihydrodipicolinate reductase subunit (EC 1.17.1.8) from Bacillus subtilis (strain 168) (see 3 papers)
    30% identity, 97% coverage of query (109 bits)

dapB / CAA79712.1 dihydrodipicolinate reductase from Corynebacterium glutamicum (see paper)
    30% identity, 98% coverage of query (100 bits)

CA265_RS15670 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Pedobacter sp. GW460-11-11-14-LB5
    31% identity, 72% coverage of query (100 bits)

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Build an alignment for 7023736 and 26 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

dapB / P40110 dihydropicolinate reductase subunit (EC 1.17.1.8) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 2 papers)
P40110 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Corynebacterium glutamicum (see paper)
    29% identity, 98% coverage of query (98.6 bits)

5eerA / P40110 Crystal structure of dapb from corynebacterium glutamicum (see paper)
    29% identity, 98% coverage of query (98.6 bits)

5eesA Crystal structure of dapb in complex with NADP+ from corynebacterium glutamicum
    29% identity, 98% coverage of query (98.6 bits)

1p9lA Structure of m. Tuberculosis dihydrodipicolinate reductase in complex with nadh and 2,6 pdc
    29% identity, 95% coverage of query (98.2 bits)

1c3vA Dihydrodipicolinate reductase from mycobacterium tuberculosis complexed with NADPH and pdc
    29% identity, 95% coverage of query (98.2 bits)

5ugvA Dapb from mycobacterium tuberculosis
    29% identity, 95% coverage of query (98.2 bits)

5tjzA Structure of 4-hydroxytetrahydrodipicolinate reductase from mycobacterium tuberculosis with NADPH and 2,6 pyridine dicarboxylic acid
    29% identity, 95% coverage of query (98.2 bits)

dapB / P9WP23 dihydropicolinate reductase subunit (EC 1.17.1.8) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
DAPB_MYCTU / P9WP23 4-hydroxy-tetrahydrodipicolinate reductase; HTPA reductase; EC 1.17.1.8 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WP23 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Mycobacterium tuberculosis (see 3 papers)
    29% identity, 95% coverage of query (97.8 bits)

1yl5A / P9WP23 Crystal structure of mycobacterium tuberculosis dihydrodipicolinate reductase (rv2773c) (crystal form a) (see paper)
    30% identity, 94% coverage of query (97.4 bits)

Echvi_2395 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Echinicola vietnamensis KMM 6221, DSM 17526
    31% identity, 80% coverage of query (94.0 bits)

5wolA / P24703 Crystal structure of dihydrodipicolinate reductase dapb from coxiella burnetii
    28% identity, 97% coverage of query (80.9 bits)

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