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Searching for up to 100 curated homologs for 7025626 FitnessBrowser__ANA3:7025626 (216 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SO1671 Maleylacetoacetate isomerase (EC 5.2.1.2) from Shewanella oneidensis MR-1
    96% identity, 100% coverage of query (432 bits)

Psest_3511 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas stutzeri RCH2
    62% identity, 100% coverage of query (267 bits)

Ac3H11_2306 Maleylacetoacetate isomerase (EC 5.2.1.2) from Acidovorax sp. GW101-3H11
    53% identity, 99% coverage of query (220 bits)

Q5K5T6 glutathione transferase subunit (EC 2.5.1.18) from Escherichia coli (see 8 papers)
    50% identity, 100% coverage of query (210 bits)

2v6kA / O86043 Structure of maleyl pyruvate isomerase, a bacterial glutathione-s- transferase in zeta class, in complex with substrate analogue dicarboxyethyl glutathione (see paper)
    53% identity, 100% coverage of query (206 bits)

nagL / O86043 glutathion-dependent maleylpyruvate isomerase (EC 5.2.1.4) from Ralstonia sp. (see paper)
NAGL_RALSP / O86043 Maleylpyruvate isomerase; MPI; Naphthalene degradation protein L; EC 5.2.1.4 from Ralstonia sp. (see 2 papers)
    53% identity, 100% coverage of query (206 bits)

2jl4A Holo structure of maleyl pyruvate isomerase, a bacterial glutathione- s-transferase in zeta class
    53% identity, 100% coverage of query (206 bits)

MAAI2_DROME / Q9VHD2 Probable maleylacetoacetate isomerase 2; MAAI 2; Glutathione S-transferase zeta 2; EC 5.2.1.2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    46% identity, 99% coverage of query (198 bits)

1fw1A / O43708 Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
    48% identity, 99% coverage of query (191 bits)

GSTZ1 / O43708 maleylacetoacetate isomerase/glutathione transferase ζ monomer (EC 2.5.1.18; EC 5.2.1.2) from Homo sapiens (see 11 papers)
MAAI_HUMAN / O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
O43708 glutathione transferase (EC 2.5.1.18); maleylacetoacetate isomerase (EC 5.2.1.2) from Homo sapiens (see 8 papers)
    48% identity, 99% coverage of query (189 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    46% identity, 99% coverage of query (185 bits)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
    46% identity, 99% coverage of query (185 bits)

Pf6N2E2_5292 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E2
    50% identity, 99% coverage of query (183 bits)

AO356_16835 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2C3
    50% identity, 99% coverage of query (183 bits)

MAAI_RAT / P57113 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Rattus norvegicus (Rat) (see paper)
    45% identity, 99% coverage of query (181 bits)

AO353_15560 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E3
    46% identity, 99% coverage of query (181 bits)

GSTZ1_ARATH / Q9ZVQ3 Glutathione S-transferase Z1; AtGSTZ1; GST class-zeta member 1; Glutathione S-transferase 18; Maleylacetone isomerase; MAI; EC 2.5.1.18; EC 5.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    45% identity, 100% coverage of query (180 bits)

MAAI1_DROME / Q9VHD3 Probable maleylacetoacetate isomerase 1; MAAI 1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    38% identity, 99% coverage of query (160 bits)

4pxoA / C5ATQ9 Crystal structure of maleylacetoacetate isomerase from methylobacteriu extorquens am1 with bound malonate and gsh (target efi-507068)
    42% identity, 100% coverage of query (160 bits)

4kdyA / B8J605 Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans 2cp-1, target efi-507175, with bound gsh in the active site
    43% identity, 100% coverage of query (154 bits)

4kaeA Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans 2cp-1, target efi-507175, with bound dicarboxyethyl glutathione and citrate in the active site
    43% identity, 100% coverage of query (154 bits)

3n5oA / D2YW48 Crystal structure of putative glutathione transferase from coccidioides immitis bound to glutathione (see paper)
    39% identity, 100% coverage of query (149 bits)

D2YW48 Probable glutathione S-transferase; EC 2.5.1.18 from Coccidioides immitis (strain RS) (Valley fever fungus)
    39% identity, 100% coverage of query (148 bits)

MAIA_ASPFU / Q4WHT7 Maleylacetoacetate isomerase maiA; EC 5.2.1.2 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 3 papers)
    40% identity, 90% coverage of query (143 bits)

maiA / O43123 maleylacetoacetate isomerase (EC 5.2.1.2) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (see paper)
MAAI_EMENI / O43123 Maleylacetoacetate isomerase; MAAI; EC 5.2.1.2 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
O43123 maleylacetoacetate isomerase (EC 5.2.1.2) from Aspergillus nidulans (see paper)
GI|2832725 maleylacetoacetate isomerase; EC 5.2.1.2 from Emericella nidulans (see paper)
maiA / CAA05041.1 maleylacetoacetate isomerase from Aspergillus nidulans (see paper)
maiA / CAA05044.1 maleylacetoacetate isomerase from Aspergillus nidulans (see paper)
    40% identity, 90% coverage of query (140 bits)

O04437 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    39% identity, 99% coverage of query (134 bits)

Build an alignment

Build an alignment for 7025626 and 26 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

A0A4Y5QZX9 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 81% coverage of query (62.8 bits)

GSTD5_DROME / Q9VG95 Glutathione S-transferase D5; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    30% identity, 75% coverage of query (62.4 bits)

GSTD7_DROME / Q9VG93 Glutathione S-transferase D7; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    27% identity, 89% coverage of query (62.0 bits)

GSTD3_DROME / Q9VG97 Inactive glutathione S-transferase D3 from Drosophila melanogaster (Fruit fly) (see paper)
    28% identity, 76% coverage of query (62.0 bits)

B3VQJ6 glutathione transferase (EC 2.5.1.18) from Phanerodontia chrysosporium (see paper)
    29% identity, 80% coverage of query (61.2 bits)

4pnfB / Q7JZM3 Glutathione s-transferase from drosophila melanogaster - isozyme e6 (see paper)
    30% identity, 96% coverage of query (60.5 bits)

Q59721 4-chlorobenzoate dehalogenase (EC 3.8.1.6) from Burkholderia sp. (see paper)
bphK / CAA54033.1 glutathione S-transferase from Paraburkholderia xenovorans LB400 (see paper)
    27% identity, 88% coverage of query (59.7 bits)

2gdrA / Q59721 Crystal structure of a bacterial glutathione transferase (see paper)
    27% identity, 88% coverage of query (59.3 bits)

3qawA / B9VX79 Crystal structure of a glutathione-s-transferase from antarctic clam laternula elliptica in a complex with glutathione (see paper)
    26% identity, 99% coverage of query (59.3 bits)

2dsaA Ternary complex of bphk, a bacterial gst
    27% identity, 88% coverage of query (59.3 bits)

3m3mA / Q4K8I0 Crystal structure of glutathione s-transferase from pseudomonas fluorescens [pf-5]
    26% identity, 88% coverage of query (58.9 bits)

Q9FQE8 glutathione transferase (EC 2.5.1.18) from Glycine max (see paper)
    29% identity, 79% coverage of query (58.9 bits)

4chsA Crystal structure of a tau class glutathione transferase 10 from glycine max
    29% identity, 79% coverage of query (58.9 bits)

5zwpA / P28338 Crystal structure of the delta-class glutathione transferase from musca domestica (see paper)
    29% identity, 80% coverage of query (58.5 bits)

A0A4Y5R0C1 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    28% identity, 79% coverage of query (58.2 bits)

GSTF3_MAIZE / P04907 Glutathione S-transferase 3; GST class-phi member 3; GST-III; EC 2.5.1.18 from Zea mays (Maize) (see 2 papers)
    31% identity, 94% coverage of query (57.8 bits)

GSTD2_DROME / Q9VG98 Glutathione S-transferase D2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
Q9VG98 glutathione transferase (EC 2.5.1.18) from Drosophila melanogaster (see paper)
    29% identity, 72% coverage of query (57.4 bits)

A0A4Y5R0K8 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 78% coverage of query (56.6 bits)

A0A4Y5R032 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    28% identity, 98% coverage of query (56.2 bits)

D2WL57 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    28% identity, 78% coverage of query (56.2 bits)

GstB / b0838 glutathione S-transferase GstB from Escherichia coli K-12 substr. MG1655 (see 6 papers)
gstB / P0ACA7 glutathione S-transferase GstB from Escherichia coli (strain K12) (see 3 papers)
GSTB_ECOLI / P0ACA7 Glutathione S-transferase GstB; EC 2.5.1.18 from Escherichia coli (strain K12) (see paper)
yliJ / MB|P0ACA7 uncharacterized GST-like protein yliJ from Escherichia coli K12 (see paper)
    29% identity, 78% coverage of query (56.2 bits)

3touA / Q8XVV6 Crystal structure of glutathione transferase (target efi-501058) from ralstonia solanacearum gmi1000 with gsh bound
    31% identity, 79% coverage of query (56.2 bits)

A0A4Y5QZX3 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    30% identity, 77% coverage of query (55.8 bits)

D2WL48 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    25% identity, 98% coverage of query (55.8 bits)

4g9hA / Q8D0L3 Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target efi-501894, with bound glutathione
    29% identity, 94% coverage of query (55.8 bits)

SSPA_COXBU / Q83AY0 Stringent starvation protein A homolog from Coxiella burnetii (strain RSA 493 / Nine Mile phase I) (see paper)
    28% identity, 87% coverage of query (55.8 bits)

4kh7B / Q8Z859 Crystal structure of a glutathione transferase family member from salmonella enterica ty2, target efi-507262, with bound glutathione
    29% identity, 77% coverage of query (55.5 bits)

7dw4A / A0A4Y5R032 Crystal structure of a glutathione s-transferase mutant sbgstu6(i55t) from salix babylonica in complex with glutathione
    28% identity, 98% coverage of query (55.5 bits)

3ublA / Q8F2Y8 Crystal structure of glutathione transferase (target efi-501770) from leptospira interrogans with gsh bound
    29% identity, 78% coverage of query (55.1 bits)

GSTD4_DROME / Q9VG96 Glutathione S-transferase D4; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    25% identity, 93% coverage of query (54.7 bits)

5agyA / I1MJ34 Crystal structure of a tau class gst mutant from glycine (see paper)
    29% identity, 79% coverage of query (54.7 bits)

GST1D_ANOGA / Q93113 Glutathione S-transferase 1, isoform D; AgGst1-alpha; Aggst1-1; Aggst1-6; Aggst2-1; DDT-dehydrochlorinase; GST class-theta; EC 2.5.1.18; EC 4.5.1.1 from Anopheles gambiae (African malaria mosquito) (see 3 papers)
1pn9A / Q93113 Crystal structure of an insect delta-class glutathione s-transferase from a ddt-resistant strain of the malaria vector anopheles gambiae (see paper)
GSTd1-6 / CAB03593.1 GSTD1-6 protein, partial from Anopheles gambiae (see 2 papers)
    31% identity, 75% coverage of query (54.7 bits)

Q56AY1 glutathione transferase (EC 2.5.1.18) from Vitis vinifera (see paper)
    32% identity, 81% coverage of query (54.7 bits)

Q2G4B4 glutathione transferase (subunit 2/2) (EC 2.5.1.18) from Novosphingobium aromaticivorans (see paper)
    25% identity, 89% coverage of query (54.3 bits)

GSTO1_PIG / Q9N1F5 Glutathione S-transferase omega-1; GSTO-1; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase; SPG-R; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Sus scrofa (Pig) (see paper)
    25% identity, 80% coverage of query (54.3 bits)

GST1 / AAA29287.1 glutathione transferase from Lucilia cuprina (see paper)
    28% identity, 84% coverage of query (53.5 bits)

P42860 glutathione transferase (EC 2.5.1.18) from Lucilia cuprina (see paper)
    28% identity, 84% coverage of query (53.5 bits)

Q6DNI8 glutathione transferase (EC 2.5.1.18) from Pinus tabuliformis (see paper)
    28% identity, 80% coverage of query (53.1 bits)

gst3b / CAB38119.1 Glutathione transferase III(b) from Zea mays (see paper)
    33% identity, 78% coverage of query (53.1 bits)

6srbB / A0A1M2V359 Crystal structure of glutathione transferase omega 3c from trametes versicolor (see paper)
    28% identity, 80% coverage of query (53.1 bits)

O49235 glutathione transferase (EC 2.5.1.18) from Glycine max (see paper)
    28% identity, 79% coverage of query (53.1 bits)

4topA Glycine max glutathione transferase
    28% identity, 79% coverage of query (53.1 bits)

3makA / P20432 Crystal structure of glutathione transferase dmgstd1 from drosophila melanogaster, in complex with glutathione (see paper)
    30% identity, 84% coverage of query (52.8 bits)

7rhpA / A0A7M7GUY7 Crystal structure of honeybee (apis mellifera) glutathione s- transferase amgstd1 (see paper)
    27% identity, 79% coverage of query (52.8 bits)

A1ZB72 glutathione transferase (EC 2.5.1.18) from Drosophila melanogaster (see paper)
4pngB / A1ZB72 Glutathione s-transferase from drosophila melanogaster - isozyme e7 (see paper)
    29% identity, 95% coverage of query (52.8 bits)

GSTD1_DROME / P20432 Glutathione S-transferase D1; DDT-dehydrochlorinase; EC 2.5.1.18; EC 4.5.1.1 from Drosophila melanogaster (Fruit fly) (see 2 papers)
    30% identity, 84% coverage of query (52.8 bits)

7y55A / A0A9E8RZN7 Crystal structure of a glutathione s-transferase tau1 from pinus densata in complex with gsh
    28% identity, 80% coverage of query (52.4 bits)

5j4uA / B9I0G5 Crystal structure of a glutathione s-transferase ptgstu30 from populus trichocarpa in complex with gsh
    28% identity, 79% coverage of query (52.4 bits)

3uarA / Q60CN1 Crystal structure of glutathione transferase (target efi-501774) from methylococcus capsulatus str. Bath with gsh bound
    27% identity, 93% coverage of query (52.0 bits)

3wywB / Q8N0B3 Structural characterization of catalytic site of a nilaparvata lugens delta-class glutathione transferase (see paper)
    26% identity, 93% coverage of query (51.6 bits)

4hz2B / A7ILT8 Crystal structure of glutathione s-transferase xaut_3756 (target efi- 507152) from xanthobacter autotrophicus py2
    29% identity, 89% coverage of query (51.2 bits)

4gf0A / A3STM0 Crystal structure of glutahtione transferase homolog from sulfitobacter, target efi-501084, with bound glutathione
    27% identity, 71% coverage of query (51.2 bits)

3pr8A / Q88RE7 Structure of glutathione s-transferase(pp0183) from pseudomonas putida in complex with gsh
    26% identity, 94% coverage of query (50.8 bits)

4mk3A / Q1LJ46 Crystal structure of a glutathione transferase family member from cupriavidus metallidurans ch34, target efi-507362, with bound glutathione sulfinic acid (gso2h)
    27% identity, 98% coverage of query (50.1 bits)

1jlvA / Q7KIF2 Anopheles dirus species b glutathione s-transferases 1-3 (see paper)
    30% identity, 74% coverage of query (49.3 bits)

3vlnA Human glutathione transferase o1-1 c32s mutant in complex with ascorbic acid
    26% identity, 90% coverage of query (48.9 bits)

4hojA / O33374 Crystal structure of glutathione transferase homolog from neisseria gonorrhoeae, target efi-501841, with bound glutathione
    24% identity, 86% coverage of query (48.9 bits)

1r5aA / Q9GQG7 Glutathione s-transferase (see paper)
    30% identity, 73% coverage of query (48.5 bits)

4qq7A / B4E6Q3 Crystal structure of putative stringent starvation protein a from burkholderia cenocepacia with bound glutathione
    27% identity, 86% coverage of query (48.1 bits)

6mhbA Glutathione s-transferase omega 1 bound to covalent inhibitor 18
    25% identity, 90% coverage of query (47.8 bits)

4is0A Structural insights into omega-class glutathione transferases: a snapshot of enzyme reduction and identification of the non-catalytic ligandin site.
    25% identity, 90% coverage of query (47.8 bits)

4yquA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-31
    25% identity, 90% coverage of query (47.8 bits)

6pnnA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n-(2- methoxyethyl)-n-methylsulfamoyl)phenyl)acetamide
    25% identity, 90% coverage of query (47.0 bits)

6pnoA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n- isopropylsulfamoyl)phenyl)acetamide
    25% identity, 90% coverage of query (47.0 bits)

6pnmA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3- (morpholinosulfonyl)phenyl)acetamide
    25% identity, 90% coverage of query (47.0 bits)

5v3qA Human gsto1-1 complexed with ml175
    25% identity, 90% coverage of query (47.0 bits)

5uehA Structure of gsto1 covalently conjugated to quinolinic acid fluorosulfate
    25% identity, 90% coverage of query (47.0 bits)

6mhdA Glutathione s-transferase omega 1 bound to covalent inhibitor 44
    25% identity, 90% coverage of query (47.0 bits)

6mhcA / P78417 Glutathione s-transferase omega 1 bound to covalent inhibitor 37 (see paper)
    25% identity, 90% coverage of query (47.0 bits)

GSTO1 / P78417 glutathione transferase, Ω class subunit (EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2) from Homo sapiens (see 2 papers)
GSTO1_HUMAN / P78417 Glutathione S-transferase omega-1; GSTO-1; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase; SPG-R; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Homo sapiens (Human) (see 5 papers)
P78417 methylarsonate reductase (EC 1.20.4.2); glutathione dehydrogenase (ascorbate) (EC 1.8.5.1); glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 7 papers)
    25% identity, 90% coverage of query (47.0 bits)

4yqvA Glutathione s-transferase omega 1 bound to covalent inhibitor c4-10
    25% identity, 90% coverage of query (47.0 bits)

4yqmA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-27
    25% identity, 90% coverage of query (47.0 bits)

1eemA Glutathione transferase from homo sapiens
    25% identity, 90% coverage of query (47.0 bits)

7db0A Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in dimedone-bound form
    27% identity, 94% coverage of query (45.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory