Sites on a Tree

 

Searching for up to 100 curated homologs for 7025629 FitnessBrowser__ANA3:7025629 (112 a.a.)

Found high-coverage hits (≥70%) to 8 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q02I31 Putative pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Pseudomonas aeruginosa (strain UCBPP-PA14)
    72% identity, 98% coverage of query (180 bits)

Q48G05 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Pseudomonas syringae (see paper)
    69% identity, 96% coverage of query (177 bits)

PDL2_ARATH / Q6QJ72 Pterin-4-alpha-carbinolamine dehydratase 2, mitochondrial; 4-alpha-hydroxy-tetrahydropterin dehydratase; PCD/DCoH-like protein 2; EC 4.2.1.96 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    36% identity, 96% coverage of query (77.8 bits)

Build an alignment

Build an alignment for 7025629 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

ATP1_ARATH / Q9LU63 Probable pterin-4-alpha-carbinolamine dehydratase, chloroplastic; 4-alpha-hydroxy-tetrahydropterin dehydratase; PCD/DCoH-like protein 1; Protein AIRP2 TARGET PROTEIN 1; Protein SDIR1-INTERACTING PROTEIN 1; EC 4.2.1.96 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    28% identity, 96% coverage of query (57.0 bits)

Q2Q449 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Toxoplasma gondii (see paper)
    30% identity, 80% coverage of query (48.1 bits)

2v6tB / Q2Q449 Crystal structure of a complex of pterin-4a-carbinolamine dehydratase from toxoplasma gondii with 7,8-dihydrobiopterin (see paper)
    31% identity, 78% coverage of query (48.1 bits)

PHS_DROME / O76454 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Drosophila melanogaster (Fruit fly) (see paper)
    33% identity, 78% coverage of query (45.1 bits)

PHS2_MOUSE / Q9CZL5 Pterin-4-alpha-carbinolamine dehydratase 2; PHS 2; 4-alpha-hydroxy-tetrahydropterin dehydratase 2; DcoH-like protein DCoHm; Dimerization cofactor of hepatocyte nuclear factor 1 from muscle; HNF-1-alpha dimerization cofactor; EC 4.2.1.96 from Mus musculus (Mouse) (see paper)
    34% identity, 84% coverage of query (44.7 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory