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Searching for up to 100 curated homologs for 7026062 FitnessBrowser__ANA3:7026062 (221 a.a.)

Found high-coverage hits (≥70%) to 39 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

murU / Q88QT2 N-acetyl-α-D-muramate 1-phosphate uridylyltransferase (EC 2.7.7.99) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
MURU_PSEPK / Q88QT2 N-acetylmuramate alpha-1-phosphate uridylyltransferase; MurNAc-1P uridylyltransferase; MurNAc-alpha-1P uridylyltransferase; EC 2.7.7.99 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
Q88QT2 N-acetyl-alpha-D-muramate 1-phosphate uridylyltransferase (EC 2.7.7.99) from Pseudomonas putida (see 5 papers)
    55% identity, 99% coverage of query (219 bits)

4y7uA / Q88QT2 Structural analysis of muru (see paper)
    55% identity, 99% coverage of query (218 bits)

MURU_NEIMB / Q9JXY0 N-acetylmuramate alpha-1-phosphate uridylyltransferase; MurNAc-1P uridylyltransferase; MurNAc-alpha-1P uridylyltransferase; EC 2.7.7.99 from Neisseria meningitidis serogroup B (strain MC58) (see paper)
    54% identity, 99% coverage of query (216 bits)

4y7vA Structural analysis of muru
    54% identity, 99% coverage of query (213 bits)

MURU_PSEAE / Q9I5U0 N-acetylmuramate alpha-1-phosphate uridylyltransferase; MurNAc-1P uridylyltransferase; MurNAc-alpha-1P uridylyltransferase; EC 2.7.7.99 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    52% identity, 100% coverage of query (199 bits)

CUGP_SYNY3 / P74285 UTP--glucose-1-phosphate uridylyltransferase; Cyanobacterial UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase; UDP-Glc PPase; EC 2.7.7.9 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
P74285 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Synechocystis sp. (see paper)
    32% identity, 100% coverage of query (92.4 bits)

MURU_CAUVC / Q9A2M1 N-acetylmuramate alpha-1-phosphate uridylyltransferase; MurNAc-1P uridylyltransferase; MurNAc-alpha-1P uridylyltransferase; EC 2.7.7.99 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see paper)
    37% identity, 93% coverage of query (89.7 bits)

MPG1_SCHPO / O74484 Mannose-1-phosphate guanyltransferase; GDP-mannose pyrophosphorylase; GTP-mannose-1-phosphate guanylyltransferase; EC 2.7.7.13 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
mpg1 / RF|NP_588405.1 mannose-1-phosphate guanyltransferase Mpg1; EC 2.7.7.13 from Schizosaccharomyces pombe (see 2 papers)
    33% identity, 94% coverage of query (89.0 bits)

Build an alignment

Build an alignment for 7026062 and 8 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

GMPPB_DANRE / Q6DBU5 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
Q6DBU5 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Danio rerio (see paper)
    29% identity, 94% coverage of query (87.4 bits)

mtmD / Q194R4 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces argillaceus (see paper)
mtmD / CAK50774.1 dTDP-glucose synthase from Streptomyces argillaceus (see 21 papers)
    31% identity, 95% coverage of query (78.2 bits)

Q54K39 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Solanum lycopersicum (see paper)
    29% identity, 94% coverage of query (77.8 bits)

Q6Z9A3 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Oryza sativa Japonica Group (see paper)
    30% identity, 94% coverage of query (77.4 bits)

agl11 / D4GU70 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
AGL11_HALVD / D4GU70 Low-salt glycan biosynthesis nucleotidyltransferase Agl11; EC 2.7.7.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    31% identity, 94% coverage of query (75.5 bits)

GLMU_METJA / Q58501 Bifunctional protein GlmU; EC 2.7.7.23; EC 2.3.1.157 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
    31% identity, 94% coverage of query (75.5 bits)

A0A4Y1W0P1 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Bacillus anthracis (see paper)
    28% identity, 97% coverage of query (74.3 bits)

3hl3A / A0A6L8PCC3 2.76 angstrom crystal structure of a putative glucose-1-phosphate thymidylyltransferase from bacillus anthracis in complex with a sucrose.
    28% identity, 97% coverage of query (74.3 bits)

4ecmA 2.3 angstrom crystal structure of a glucose-1-phosphate thymidylyltransferase from bacillus anthracis in complex with thymidine-5-diphospho-alpha-d-glucose and pyrophosphate
    28% identity, 97% coverage of query (73.9 bits)

B9WNA1 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Trypanosoma brucei (see paper)
    29% identity, 94% coverage of query (73.2 bits)

ptmE / Q0P8S9 glucosamine-1-phosphate guanylyltransferase from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
    26% identity, 93% coverage of query (72.0 bits)

cps19fL / AAC44969.1 glucose-1-phosphate thymidyl transferase from Streptococcus pneumoniae (see 2 papers)
    29% identity, 95% coverage of query (69.7 bits)

rmlA / AAA16191.1 glucose-1-phosphate thymidyltransferase from Xanthomonas campestris pv. campestris (see 4 papers)
    32% identity, 86% coverage of query (66.6 bits)

rmlA / Q6E7F3 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Escherichia coli (see paper)
    29% identity, 95% coverage of query (66.2 bits)

GMPPA_HUMAN / Q96IJ6 Mannose-1-phosphate guanyltransferase alpha; GDP-mannose pyrophosphorylase A; GMPP-alpha; GTP-mannose-1-phosphate guanylyltransferase alpha from Homo sapiens (Human) (see paper)
    30% identity, 100% coverage of query (64.7 bits)

RMLA_BACSU / P39629 Glucose-1-phosphate thymidylyltransferase; Spore coat polysaccharide biosynthesis protein SpsI; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase; EC 2.7.7.24 from Bacillus subtilis (strain 168) (see paper)
    27% identity, 95% coverage of query (64.7 bits)

3pkqA Q83d variant of s. Enterica rmla with dgtp
    29% identity, 94% coverage of query (63.5 bits)

6n0uA / B2JFC5 Crystal structure of a glucose-1-phosphate thymidylyltransferase from burkholderia phymatum bound to 2'-deoxy-thymidine-b-l-rhamnose
    27% identity, 95% coverage of query (62.4 bits)

RMLA_SALTY / P26393 Glucose-1-phosphate thymidylyltransferase; dTDP-glucose pyrophosphorylase; Ep; dTDP-glucose synthase; EC 2.7.7.24 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    29% identity, 94% coverage of query (61.2 bits)

GMPPA_MOUSE / Q922H4 Mannose-1-phosphate guanyltransferase alpha; GDP-mannose pyrophosphorylase A; GTP-mannose-1-phosphate guanylyltransferase alpha from Mus musculus (Mouse) (see paper)
    27% identity, 100% coverage of query (61.2 bits)

3pkpB Q83s variant of s. Enterica rmla with datp
    29% identity, 94% coverage of query (60.5 bits)

3pkpA Q83s variant of s. Enterica rmla with datp
    29% identity, 94% coverage of query (60.5 bits)

RMLA3_ECOLX / P55253 Glucose-1-phosphate thymidylyltransferase; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase; EC 2.7.7.24 from Escherichia coli (see paper)
rmlA / AAC63614.1 RmlA from Escherichia coli (see 6 papers)
    28% identity, 94% coverage of query (60.1 bits)

1iinA Thymidylyltransferase complexed with udp-glucose
    28% identity, 94% coverage of query (60.1 bits)

1iimA Thymidylyltransferase complexed with ttp
    28% identity, 94% coverage of query (60.1 bits)

4hocA Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with udp-n- acetylglucosamine
    28% identity, 95% coverage of query (59.7 bits)

4ho9A / Q9AGY4 Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with udp-galactose and utp
    28% identity, 95% coverage of query (58.5 bits)

4ho6A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with udp-glucose and utp
    28% identity, 95% coverage of query (58.5 bits)

4ho5A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with tdp-glucose
    28% identity, 95% coverage of query (58.5 bits)

4ho3A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with thymidine triphosphate
    28% identity, 95% coverage of query (58.5 bits)

6b5kA Mycobacterium tuberculosis rmla in complex with mg/dttp
    31% identity, 76% coverage of query (58.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory