Searching for up to 100 curated homologs for 7026138 FitnessBrowser__ANA3:7026138 (326 a.a.)
Found high-coverage hits (≥70%) to 60 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
FhuC / b0151 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FhuC / P07821 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see paper)
FHUC_ECOLI / P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.3 / P07821 FhuC aka B0151, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 6 papers)
fhuC / GB|BAB96727.2 ferrichrome transport ATP-binding protein FhuC; EC 3.6.3.34 from Escherichia coli K12 (see 8 papers)
39% identity, 78% coverage of query (193 bits)
FepC / b0588 ferric enterobactin ABC transporter ATP binding subunit (EC 7.2.2.17) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
FepC / P23878 ferric enterobactin ABC transporter ATP binding subunit (EC 7.2.2.17) from Escherichia coli (strain K12) (see 3 papers)
FEPC_ECOLI / P23878 Ferric enterobactin transport ATP-binding protein FepC; EC 7.2.2.17 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.2 / P23878 FepC aka B0588, component of Iron (Fe3+)-enterobactin porter from Escherichia coli (see 3 papers)
37% identity, 76% coverage of query (184 bits)
TC 3.A.1.14.10 / Q99YA4 Putative ABC transporter aka SiaC, component of The heme porter, Shp/SiaABC (HtsABC). Shp is a cell surface heme binding protein that transfers the heme directly to HstA (Nygaard et al., 2006). The crystal structure of the heme binding domain of Shp has been solved (Aranda et al., 2007). HtsABC is required for the uptake of staphyloferrin A (Beasley et al. 2009). The Shp cell surface heme receptor feeds iron-heme to the transporter in preparation for uptake from Streptococcus pyogenes serotype M1 (see 2 papers)
39% identity, 71% coverage of query (177 bits)
TC 3.A.1.14.8 / Q8GRB0 PvuE, component of The iron-vibrioferrin uptake porter from Vibrio parahaemolyticus (see paper)
36% identity, 75% coverage of query (172 bits)
TC 3.A.1.14.6 / Q9RCF3 ViuC, component of The iron-vibriobactin/enterobactin uptake porter from Vibrio cholerae (see 2 papers)
36% identity, 80% coverage of query (169 bits)
FecE / b4287 ferric citrate ABC transporter ATP binding subunit (EC 7.2.2.18) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
FecE / P15031 ferric citrate ABC transporter ATP binding subunit (EC 7.2.2.18) from Escherichia coli (strain K12) (see 2 papers)
FECE_ECOLI / P15031 Fe(3+) dicitrate transport ATP-binding protein FecE; Iron(III) dicitrate transport ATP-binding protein FecE; EC 7.2.2.18 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.1 / P15031 Fe(3+) dicitrate transport ATP-binding protein FecE, component of Iron (Fe3+) or ferric-dicitrate porter from Escherichia coli (strain K12) (see 4 papers)
fecE / GB|AAC77243.1 iron(III) dicitrate transport ATP-binding protein FecE from Escherichia coli K12 (see 6 papers)
34% identity, 76% coverage of query (167 bits)
BTUDA_HALSA / Q9HQ18 Cobalamin import ATP-binding protein BtuD; Vitamin B12-transporting ATPase; EC 7.6.2.8 from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) (see paper)
37% identity, 83% coverage of query (166 bits)
TC 3.A.1.14.14 / Q9A197 Putative ferrichrome ABC transporter aka SiuA aka Spy0386, component of The Fe3+ /Fe3+ferrichrome/Fe3+heme uptake porter; SiuABDG (FTSABCD) from Streptococcus pyogenes serotype M1 (see 2 papers)
36% identity, 74% coverage of query (165 bits)
TC 3.A.1.14.7 / Q9X665 FhuC aka FhuA, component of Iron (Fe3+)-hydroxamate porter (transports Fe3+-ferrichrome and Fe3+-ferrioxamine B with FhuD1, and these compounds plus aerobactin and coprogen with FhuD2) (see 2 papers)
36% identity, 72% coverage of query (161 bits)
YUSV_BACSU / O32188 Probable siderophore transport system ATP-binding protein YusV from Bacillus subtilis (strain 168) (see 2 papers)
35% identity, 76% coverage of query (160 bits)
FPUD_BACAN / Q81V82 Petrobactin import ATP-binding protein FpuD; EC 7.2.2.- from Bacillus anthracis (see paper)
34% identity, 76% coverage of query (158 bits)
TC 3.A.1.14.4 / Q47087 CbrD, component of Iron-chrysobactine porter from Erwinia chrysanthemi (see paper)
cbrD / GB|CAA60669.1 achromobactin ABC transporter, ATP-binding protein CbrD from Erwinia chrysanthemi str. 3937 (see paper)
35% identity, 73% coverage of query (155 bits)
TC 3.A.1.14.20 / Q7W025 Hemin import ATP-binding protein HmuV, component of Heme-iron (hemin) utilization transporter BhuTUV from Bordetella pertussis (see paper)
36% identity, 74% coverage of query (154 bits)
TC 3.A.1.14.19 / Q93SS1 Hemin import ATP-binding protein hmuV, component of Heme uptake porter, HugBCD (Villarreal et al., 2008); also called HmuTUV from Plesiomonas shigelloides (see paper)
38% identity, 71% coverage of query (152 bits)
fhuC / GI|2832798 ferrichrome transport ATP-binding protein FhuC from Bacillus subtilis (see paper)
33% identity, 76% coverage of query (152 bits)
TC 3.A.1.14.21 / O68877 Hemin import ATP-binding protein HmuV, component of The heme uptake porter, PhuTUV (transports one heme per reaction cycle) from Pseudomonas aeruginosa (see 2 papers)
40% identity, 76% coverage of query (152 bits)
TC 3.A.1.14.18 / Q32AY3 Hemin import ATP-binding protein hmuV, component of The heme uptake porter, ShuTUV (Burkhard and Wilks, 2008). Transports a single heme per reaction cycle (Mattle et al., 2010). (3-d structure of ShuT is known (2RG7) from Shigella dysenteriae serotype 1 (strain Sd197) (see paper)
34% identity, 74% coverage of query (151 bits)
TC 3.A.1.14.5 / Q56993 HmuV aka YPO0279 aka Y0539, component of Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle from Yersinia pestis (see 4 papers)
hmuV hemin import ATP-binding protein hmuV; EC 3.6.3.- from Yersinia pestis KIM (see paper)
33% identity, 76% coverage of query (150 bits)
TC 3.A.1.14.12 / Q9L177 DesC, component of Desferrioxamine B uptake porter, DesABC from Streptomyces coelicolor (see paper)
34% identity, 75% coverage of query (149 bits)
FPUC_BACAN / Q81LM1 Petrobactin import ATP-binding protein FpuC; EC 7.2.2.- from Bacillus anthracis (see paper)
32% identity, 79% coverage of query (145 bits)
TC 3.A.1.14.16 / A8GDS6 HemV, component of The heme-specific uptake porter, HemTUV from Serratia proteamaculans (strain 568)
35% identity, 76% coverage of query (137 bits)
hmuV / CAC34395.1 HmuV protein from Rhizobium leguminosarum (see paper)
30% identity, 79% coverage of query (132 bits)
YCLP_BACSU / P94420 Petrobactin import ATP-binding protein YclP; EC 7.2.2.- from Bacillus subtilis (strain 168) (see paper)
32% identity, 71% coverage of query (131 bits)
5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
30% identity, 78% coverage of query (110 bits)
ABC1_MYCTU / O65934 ABC transporter ATP-binding/permease protein Rv1747; EC 7.-.-.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
31% identity, 72% coverage of query (107 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
30% identity, 78% coverage of query (106 bits)
7vgfA / O75027 Cryo-em structure of amp-pnp bound human abcb7
32% identity, 70% coverage of query (104 bits)
ABCB7_HUMAN / O75027 Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette transporter 7; ABC transporter 7 protein from Homo sapiens (Human) (see 8 papers)
TC 3.A.1.210.4 / O75027 ABC7 or ABCB7 iron transporter (X-linked sideroblastis anemia protein, XLSA/A (Fujiwara and Harigae 2013)) from Homo sapiens (Human) (see 9 papers)
32% identity, 70% coverage of query (103 bits)
Build an alignment for 7026138 and 28 homologs with ≥ 30% identity
Or download the sequences
sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
28% identity, 74% coverage of query (103 bits)
AB25B_ARATH / Q9LVM1 ABC transporter B family member 25, mitochondrial; ABC transporter ABCB.25; AtABCB25; ABC transporter of the mitochondrion 3; AtATM3; Iron-sulfur clusters transporter ATM3; Protein STARIK 1 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
TC 3.A.1.210.8 / Q9LVM1 Mitochondrial ABC transporter, ATM3, involved in iron homeostasis (Chen et al. 2007) and heavy metal resistance (Kim et al. 2006). There are three isoforms: ATM1, ATM2 and ATM3 (Chen et al., 2007). ATM3 can replace the yeast iron/sulfur cluster exporter better than ATM1 or ATM2. Atm3 is most similar to the human and yeast homologues, TC# 3.A.1.210.4 and 3.A.1.210.1, 51% and 47% identical, respectively from Arabidopsis thaliana (Mouse-ear cress) (see 11 papers)
GB|AAN13224.1 putative ABC transporter protein from Arabidopsis thaliana (see paper)
29% identity, 72% coverage of query (99.4 bits)
8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
29% identity, 73% coverage of query (95.9 bits)
7sgrE / Q8FDZ8 Structure of hemolysin a secretion system hlyb/d complex (see paper)
28% identity, 72% coverage of query (95.5 bits)
8hprD Lpqy-sugabc in state 4
29% identity, 72% coverage of query (94.7 bits)
8hprC Lpqy-sugabc in state 4
29% identity, 72% coverage of query (94.7 bits)
6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
26% identity, 71% coverage of query (94.4 bits)
8dckA Structure of hemolysin a secretion system hlyb/d complex, atp-bound
28% identity, 72% coverage of query (94.0 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
26% identity, 82% coverage of query (91.7 bits)
6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
26% identity, 71% coverage of query (89.4 bits)
6b89A E. Coli lptb in complex with adp and novobiocin
26% identity, 71% coverage of query (89.4 bits)
4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
26% identity, 71% coverage of query (89.4 bits)
6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
26% identity, 71% coverage of query (89.4 bits)
6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
26% identity, 71% coverage of query (89.4 bits)
6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
26% identity, 71% coverage of query (89.4 bits)
8t1pD Heterodimeric abc transporter bmrcd in the occluded conformation bound to adpvi: bmrcd_oc-adpvi
30% identity, 71% coverage of query (89.0 bits)
6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
26% identity, 71% coverage of query (87.8 bits)
8fpfD / O07549 Heterodimeric abc transporter bmrcd in the inward-facing conformation bound to atp: bmrcd_if-atp (see paper)
29% identity, 71% coverage of query (87.4 bits)
8fmvD Heterodimeric abc transporter bmrcd in the inward-facing conformation bound to substrate and atp: bmrcd_if-2ht/atp
29% identity, 71% coverage of query (87.4 bits)
2ixfA / P36370 Crystal structure of the atpase domain of tap1 with atp (d645q, q678h mutant) (see paper)
29% identity, 72% coverage of query (86.3 bits)
8ipsA / P23886 Cryo-em structure of heme transporter cyddc from escherichia coli in the inward facing heme loading state (see paper)
30% identity, 71% coverage of query (84.3 bits)
7zdaC If(apo/asym) conformation of cyddc in adp+pi(cydc)/atp(cydd) bound state (dataset-2)
30% identity, 71% coverage of query (83.2 bits)
7zdkC If(apo/asym) conformation of cyddc in amp-pnp(cydc)/amp-pnp(cydd) bound state (dataset-8)
30% identity, 71% coverage of query (83.2 bits)
7zdfC If(heme/confined) conformation of cyddc in amp-pnp(cydd) bound state (dataset-4)
30% identity, 71% coverage of query (83.2 bits)
7zdtC Occ(apo/return) conformation of cyddc mutant (e500q.C) in atp(cydc) bound state (dataset-18)
30% identity, 71% coverage of query (81.6 bits)
P0A9U3 Probable ATP-binding protein YbiT from Escherichia coli (strain K12)
28% identity, 71% coverage of query (80.5 bits)
YbiT / b0820 putative ATP-binding protein YbiT from Escherichia coli K-12 substr. MG1655 (see 7 papers)
YBIT_ECOL6 / P0A9U4 Probable ATP-binding protein YbiT from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
ybiT / MB|P0A9U3 uncharacterized ABC transporter ATP-binding protein ybiT from Escherichia coli K12 (see 2 papers)
28% identity, 71% coverage of query (80.5 bits)
ABCBB_HUMAN / O95342 Bile salt export pump; ATP-binding cassette sub-family B member 11; EC 7.6.2.- from Homo sapiens (Human) (see 21 papers)
TC 3.A.1.201.2 / O95342 Bile salt export pump, BSEP, ABCB11 or SPGP in the canalicular membrane of liver cells, is associated with progressive familial intrahepatic cholestasis-2 and benign recurrent intrahepatic cholestasis (Kagawa et al., 2008; Stindt et al. 2013; Park et al. 2016). It exports unconjugaged bile salts and glycine conjugates > taurine conjugates as well as the statin, pravastatin (Nigam 2015). BSEP mediates biliary excretion of bile acids from hepatocytes. Compounds based on GW4064 (Q96RI1), a representative farnesoid X receptor (RXR) agonist, enhance E297G BSEP transport activity from Homo sapiens (Human) (see 11 papers)
27% identity, 81% coverage of query (77.4 bits)
CFTR_MOUSE / P26361 Cystic fibrosis transmembrane conductance regulator; CFTR; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel; EC 5.6.1.6 from Mus musculus (Mouse) (see 12 papers)
P26361 adenylate kinase (EC 2.7.4.3); channel-conductance-controlling ATPase (EC 5.6.1.6) from Mus musculus (see 2 papers)
27% identity, 72% coverage of query (75.1 bits)
5dgxA / Q14JW6 1.73 angstrom resolution crystal structure of the abc-atpase domain (residues 357-609) of lipid a transport protein (msba) from francisella tularensis subsp. Tularensis schu s4 in complex with adp
26% identity, 70% coverage of query (74.3 bits)
6uy0A Cryo-em structure of wild-type bovine multidrug resistance protein 1 (mrp1) under active turnover conditions
23% identity, 79% coverage of query (57.4 bits)
RbsA / b3749 ribose ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsA / P04983 ribose ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 2 papers)
RBSA_ECOLI / P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.1 / P04983 RbsA aka B3749, component of Ribose porter from Escherichia coli (see 6 papers)
rbsA / GB|AAC76772.1 ribose transport, ATP-binding protein RbsA; EC 3.6.3.17 from Escherichia coli K12 (see 7 papers)
23% identity, 71% coverage of query (57.0 bits)
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Lawrence Berkeley National Laboratory