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Searching for up to 100 curated homologs for 7026927 FitnessBrowser__ANA3:7026927 (368 a.a.)

Found high-coverage hits (≥70%) to 15 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ProB / b0242 glutamate 5-kinase (EC 2.7.2.11) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
proB / P0A7B5 glutamate 5-kinase (EC 2.7.2.11) from Escherichia coli (strain K12) (see 32 papers)
PROB_ECOLI / P0A7B5 Glutamate 5-kinase; Gamma-glutamyl kinase; GK; EC 2.7.2.11 from Escherichia coli (strain K12) (see 3 papers)
P0A7B5 glutamate 5-kinase (EC 2.7.2.11) from Escherichia coli (see 2 papers)
proB glutamate 5-kinase; EC 2.7.2.11 from Escherichia coli K12 (see 6 papers)
    34% identity, 97% coverage of query (211 bits)

2j5tD / P0A7B5 Glutamate 5-kinase from escherichia coli complexed with glutamate (see paper)
    34% identity, 95% coverage of query (209 bits)

Q6E235 glutamate 5-kinase (EC 2.7.2.11) from Bacillus subtilis (see paper)
    36% identity, 89% coverage of query (201 bits)

proB / BAA05044.1 gamma-glutamyl kinase from Bacillus subtilis (see paper)
    34% identity, 89% coverage of query (186 bits)

Echvi_4033 glutamate 5-kinase (EC 2.7.2.11) from Echinicola vietnamensis KMM 6221, DSM 17526
    34% identity, 88% coverage of query (176 bits)

Build an alignment

Build an alignment for 7026927 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

2j5vB / P0A7B5 Glutamate 5-kinase from escherichia coli complexed with glutamyl-5- phosphate and pyroglutamic acid (see paper)
    29% identity, 95% coverage of query (161 bits)

2j5vA Glutamate 5-kinase from escherichia coli complexed with glutamyl-5- phosphate and pyroglutamic acid
    28% identity, 95% coverage of query (155 bits)

YHJ3_YEAST / P38690 Uncharacterized protein YHR033W from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    31% identity, 81% coverage of query (152 bits)

CA265_RS20855 glutamate 5-kinase (EC 2.7.2.11) from Pedobacter sp. GW460-11-11-14-LB5
    33% identity, 83% coverage of query (150 bits)

PROB_YEAST / P32264 Glutamate 5-kinase; GK; Gamma-glutamyl kinase; EC 2.7.2.11 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P32264 glutamate 5-kinase (EC 2.7.2.11) from Saccharomyces cerevisiae (see 5 papers)
    30% identity, 89% coverage of query (146 bits)

BT3719 glutamate 5-kinase (EC 2.7.2.11) from Bacteroides thetaiotaomicron VPI-5482
    29% identity, 88% coverage of query (141 bits)

P9WHU9 glutamate 5-kinase (EC 2.7.2.11) from Mycobacterium tuberculosis (see paper)
    29% identity, 97% coverage of query (140 bits)

Ga0059261_3512 glutamate 5-kinase (EC 2.7.2.11) from Sphingomonas koreensis DSMZ 15582
    34% identity, 91% coverage of query (137 bits)

P5CS_MOUSE / Q9Z110 Delta-1-pyrroline-5-carboxylate synthase; P5CS; Aldehyde dehydrogenase family 18 member A1; EC 2.7.2.11; EC 1.2.1.41 from Mus musculus (Mouse) (see paper)
Q9Z110 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Mus musculus (see paper)
    29% identity, 82% coverage of query (116 bits)

ALDH18A1 / P54886 δ-1-pyrroline-5-carboxylate synthase (EC 1.2.1.41; EC 2.7.2.11) from Homo sapiens (see 4 papers)
P5CS_HUMAN / P54886 Delta-1-pyrroline-5-carboxylate synthase; P5CS; Aldehyde dehydrogenase family 18 member A1; EC 2.7.2.11; EC 1.2.1.41 from Homo sapiens (Human) (see 8 papers)
    28% identity, 82% coverage of query (115 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory