Searching for up to 100 curated homologs for 8499247 FitnessBrowser__Miya:8499247 (572 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
pdc / Q5NYJ8 phenylpyruvate decarboxylase (EC 4.1.1.43) from Aromatoleum aromaticum (strain EbN1) (see 2 papers)
59% identity, 99% coverage of query (640 bits)
ipdC / P51852 phenylpyruvate decarboxylase (EC 4.1.1.43) from Azospirillum brasilense (see 2 papers)
P51852 indolepyruvate decarboxylase (EC 4.1.1.74) from Azospirillum brasilense (see 2 papers)
57% identity, 99% coverage of query (580 bits)
2q5qA X-ray structure of phenylpyruvate decarboxylase in complex with 3- deaza-thdp and 5-phenyl-2-oxo-valeric acid
57% identity, 99% coverage of query (579 bits)
2q5oA X-ray structure of phenylpyruvate decarboxylase in complex with 3- deaza-thdp and phenylpyruvate
57% identity, 99% coverage of query (576 bits)
2q5lA / P51852 X-ray structure of phenylpyruvate decarboxylase in complex with 2-(1- hydroxyethyl)-3-deaza-thdp (see paper)
56% identity, 99% coverage of query (564 bits)
2nxwA Crystal structure of phenylpyruvate decarboxylase of azospirillum brasilense
56% identity, 99% coverage of query (561 bits)
2q5jA X-ray structure of phenylpyruvate decarboxylase in complex with 3- deaza-thdp
55% identity, 99% coverage of query (557 bits)
ipdC / CAA67899.1 indole-3-pyruvate decarboxylase from Azospirillum brasilense (see paper)
55% identity, 99% coverage of query (556 bits)
Build an alignment for 8499247 and 8 homologs with ≥ 30% identity
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Q2UKV4 phenylpyruvate decarboxylase (EC 4.1.1.43) from Aspergillus oryzae (see paper)
28% identity, 93% coverage of query (183 bits)
5npuA Inferred ancestral pyruvate decarboxylase (see paper)
26% identity, 98% coverage of query (169 bits)
2vbfB / Q6QBS4 The holostructure of the branched-chain keto acid decarboxylase (kdca) from lactococcus lactis (see paper)
24% identity, 95% coverage of query (165 bits)
2vbgA The complex structure of the branched-chain keto acid decarboxylase (kdca) from lactococcus lactis with 2r-1-hydroxyethyl-deazathdp
24% identity, 95% coverage of query (165 bits)
6vgsBBB / A0A0B8QZ66 6vgsBBB (see paper)
24% identity, 95% coverage of query (164 bits)
ipdC / P23234 indole-3-pyruvate decarboxylase subunit (EC 4.1.1.74) from Enterobacter cloacae (see 2 papers)
DCIP_ENTCL / P23234 Indole-3-pyruvate decarboxylase; Indolepyruvate decarboxylase; EC 4.1.1.74 from Enterobacter cloacae (see paper)
P23234 indolepyruvate decarboxylase (EC 4.1.1.74) from Enterobacter cloacae (see paper)
27% identity, 97% coverage of query (161 bits)
PDC4_SCHPO / O42873 Putative pyruvate decarboxylase C3G9.11c; EC 4.1.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
26% identity, 95% coverage of query (159 bits)
A0A068LJY3 pyruvate decarboxylase (subunit 2/3) (EC 4.1.1.1) from Hevea brasiliensis (see paper)
25% identity, 97% coverage of query (158 bits)
2vbiA / Q8L388 Holostructure of pyruvate decarboxylase from acetobacter pasteurianus
25% identity, 97% coverage of query (157 bits)
1ovmA / P23234 Crystal structure of indolepyruvate decarboxylase from enterobacter cloacae (see paper)
26% identity, 97% coverage of query (157 bits)
PDC6 / P26263 pyruvate decarboxylase 3 monomer (EC 4.1.1.1; EC 4.1.1.80; EC 4.1.1.43; EC 4.1.1.74; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 9 papers)
PDC6_YEAST / P26263 Pyruvate decarboxylase isozyme 3; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
P26263 pyruvate decarboxylase (EC 4.1.1.1) from Saccharomyces cerevisiae (see 2 papers)
24% identity, 95% coverage of query (155 bits)
Q92345 Probable pyruvate decarboxylase C1F8.07c; EC 4.1.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
24% identity, 99% coverage of query (155 bits)
PDC2_ARATH / Q9FFT4 Pyruvate decarboxylase 2; AtPDC2; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9FFT4 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see 2 papers)
26% identity, 97% coverage of query (154 bits)
A0A125STX6 pyruvate decarboxylase (EC 4.1.1.1) from Phanerochaete sordida (see paper)
26% identity, 87% coverage of query (154 bits)
A0A068LQF7 pyruvate decarboxylase (EC 4.1.1.1) from Hevea brasiliensis (see paper)
26% identity, 97% coverage of query (153 bits)
PDC1_CANGA / Q6FJA3 Pyruvate decarboxylase; EC 4.1.1.1 from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus) (see paper)
25% identity, 95% coverage of query (153 bits)
Q8L388 pyruvate decarboxylase (EC 4.1.1.1) from Acetobacter pasteurianus (see paper)
24% identity, 97% coverage of query (152 bits)
Q93EN4 pyruvate decarboxylase (EC 4.1.1.1) from Sarcina ventriculi (see paper)
24% identity, 96% coverage of query (151 bits)
PDC3_ARATH / Q9M039 Pyruvate decarboxylase 3; AtPDC3; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9M039 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see paper)
25% identity, 98% coverage of query (151 bits)
PDC5 / P16467 pyruvate decarboxylase 2 monomer (EC 4.1.1.1; EC 4.1.1.43; EC 4.1.1.74; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 8 papers)
PDC5_YEAST / P16467 Pyruvate decarboxylase isozyme 2; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 15 papers)
P16467 pyruvate decarboxylase (EC 4.1.1.1) from Saccharomyces cerevisiae (see 2 papers)
25% identity, 95% coverage of query (150 bits)
A0A068LJJ5 pyruvate decarboxylase (subunit 3/3) (EC 4.1.1.1) from Hevea brasiliensis (see paper)
25% identity, 97% coverage of query (150 bits)
PDC4_ARATH / Q9M040 Pyruvate decarboxylase 4; AtPDC4; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9M040 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see paper)
25% identity, 99% coverage of query (150 bits)
A0A068LJB0 pyruvate decarboxylase (subunit 1/3) (EC 4.1.1.1) from Hevea brasiliensis (see paper)
26% identity, 98% coverage of query (150 bits)
C7JF72 pyruvate decarboxylase (EC 4.1.1.1) from Acetobacter pasteurianus (see paper)
24% identity, 97% coverage of query (149 bits)
PDC13 / AAP75899.1 pyruvate decarboxylase from Lachancea kluyveri (see paper)
24% identity, 95% coverage of query (149 bits)
PDC1 / P51850 pyruvate decarboxylase (EC 4.1.1.1) from Pisum sativum (see paper)
25% identity, 97% coverage of query (149 bits)
V6RPS5 pyruvate decarboxylase (EC 4.1.1.1) from Fusarium graminearum (see paper)
26% identity, 92% coverage of query (147 bits)
PDC1 / P06169 pyruvate decarboxylase (EC 4.1.1.1; EC 4.1.1.80; EC 4.1.1.43; EC 4.1.1.74; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 8 papers)
PDC1_YEAST / P06169 Pyruvate decarboxylase isozyme 1; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 20 papers)
P06169 pyruvate decarboxylase (EC 4.1.1.1) from Saccharomyces cerevisiae (see 4 papers)
24% identity, 95% coverage of query (147 bits)
1qpbA Pyruvate decarboyxlase from yeast (form b) complexed with pyruvamide
24% identity, 95% coverage of query (147 bits)
2vjyA / Q12629 Pyruvate decarboxylase from kluyveromyces lactis in complex with the substrate analogue methyl acetylphosphonate (see paper)
24% identity, 95% coverage of query (145 bits)
Q12629 pyruvate decarboxylase (EC 4.1.1.1) from Kluyveromyces lactis (see paper)
24% identity, 95% coverage of query (145 bits)
6efhA Pyruvate decarboxylase from kluyveromyces lactis soaked with pyruvamide
24% identity, 95% coverage of query (145 bits)
B0ZS79 pyruvate decarboxylase (EC 4.1.1.1) from Prunus armeniaca (see paper)
26% identity, 98% coverage of query (144 bits)
Q9UUT6 pyruvate decarboxylase (EC 4.1.1.1) from Zygosaccharomyces bisporus (see paper)
24% identity, 95% coverage of query (143 bits)
PDC1_ARATH / O82647 Pyruvate decarboxylase 1; AtPDC1; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
O82647 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see paper)
25% identity, 97% coverage of query (143 bits)
2vk1A / P06169 Crystal structure of the saccharomyces cerevisiae pyruvate decarboxylase variant d28a in complex with its substrate (see paper)
24% identity, 95% coverage of query (141 bits)
Q8KTX6 pyruvate decarboxylase (EC 4.1.1.1) from Zymobacter palmae (see paper)
25% identity, 99% coverage of query (137 bits)
2w93A Crystal structure of the saccharomyces cerevisiae pyruvate decarboxylase variant e477q in complex with the surrogate pyruvamide
24% identity, 95% coverage of query (137 bits)
5eujE / Q8KTX6 5eujE (see paper)
25% identity, 99% coverage of query (136 bits)
Q659I2 pyruvate decarboxylase (EC 4.1.1.1) from Wickerhamomyces anomalus (see paper)
23% identity, 86% coverage of query (135 bits)
PDC1_CANAL / P83779 Pyruvate decarboxylase; EC 4.1.1.1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see paper)
PDC11 pyruvate decarboxylase from Candida albicans (see 5 papers)
24% identity, 98% coverage of query (133 bits)
THI3 / Q07471 keto-isocaproate decarboxylase subunit (EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 4 papers)
THI3_YEAST / Q07471 Thiamine metabolism regulatory protein THI3; Keto isocaproate decarboxylase 1; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.72 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
Q07471 branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) from Saccharomyces cerevisiae (see 2 papers)
22% identity, 91% coverage of query (126 bits)
ilvB / AAB38426.1 acetolactate synthase from Mycobacterium avium (see paper)
26% identity, 93% coverage of query (123 bits)
6efgD / Q12629 Pyruvate decarboxylase from kluyveromyces lactis
24% identity, 95% coverage of query (123 bits)
pdc / P06672 pyruvate decarboxylase monomer (EC 4.1.1.1) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
P06672 pyruvate decarboxylase (EC 4.1.1.1) from Zymomonas mobilis (see 5 papers)
24% identity, 90% coverage of query (122 bits)
2wvgA Structural insights into the pre-reaction state of pyruvate decarboxylase from zymomonas mobilis
24% identity, 90% coverage of query (122 bits)
2wvaE Structural insights into the pre-reaction state of pyruvate decarboxylase from zymomonas mobilis
24% identity, 90% coverage of query (122 bits)
2wvaA Structural insights into the pre-reaction state of pyruvate decarboxylase from zymomonas mobilis
24% identity, 90% coverage of query (122 bits)
1zpdA Pyruvate decarboxylase from zymomonas mobilis
24% identity, 90% coverage of query (122 bits)
P06672 Pyruvate decarboxylase; PDC; EC 4.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
24% identity, 90% coverage of query (122 bits)
3oe1A Pyruvate decarboxylase variant glu473asp from z. Mobilis in complex with reaction intermediate 2-lactyl-thdp
24% identity, 90% coverage of query (122 bits)
A9H275 pyruvate decarboxylase (EC 4.1.1.1) from Gluconacetobacter diazotrophicus (see paper)
25% identity, 98% coverage of query (121 bits)
D9J047 pyruvate dehydrogenase system (EC 1.2.1.104); pyruvate decarboxylase (EC 4.1.1.1) from Zymomonas mobilis (see paper)
24% identity, 90% coverage of query (121 bits)
ipdC / P71323 indolepyruvate decarboxylase subunit (EC 4.1.1.74) from Enterobacter agglomerans (see paper)
25% identity, 92% coverage of query (120 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
27% identity, 98% coverage of query (120 bits)
4cokB / A9H275 Functional and structural characterization of pyruvate decarboxylase from gluconoacetobacter diazotrophicus (see paper)
25% identity, 98% coverage of query (119 bits)
A0A075Q354 pyruvate decarboxylase (EC 4.1.1.1) from Gluconacetobacter diazotrophicus (see paper)
25% identity, 98% coverage of query (118 bits)
ilv1 / RF|NP_595382.1 acetolactate synthase catalytic subunit; EC 2.2.1.6 from Schizosaccharomyces pombe (see 2 papers)
25% identity, 92% coverage of query (116 bits)
Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
23% identity, 93% coverage of query (114 bits)
thzk0150 / BAO66169.1 2-hydroxy-4-methyl-2-(2-phenylacetyl)pentanoic acid synthase from Thermosporothrix hazakensis (see paper)
25% identity, 93% coverage of query (114 bits)
8hp4A / C5MDS4 Ctpdc complex
24% identity, 98% coverage of query (113 bits)
ilvB / Q0KCU4 acetohydroxyacid synthase subunit B (EC 2.2.1.6) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
23% identity, 95% coverage of query (110 bits)
G0ZSE6 acetolactate synthase (EC 2.2.1.6) from Pseudomonas sp. (see paper)
23% identity, 96% coverage of query (108 bits)
5tmaA / P06672 Zymomonas mobilis pyruvate decarboxylase mutant pdc-2.3 (see paper)
25% identity, 90% coverage of query (107 bits)
Q5SJ01 acetolactate synthase (EC 2.2.1.6); pyruvate decarboxylase (EC 4.1.1.1) from Thermus thermophilus (see paper)
25% identity, 92% coverage of query (105 bits)
Q5S3P7 acetolactate synthase (EC 2.2.1.6) from Streptomyces cinnamonensis (see 2 papers)
ilvB / AAV52901.1 acetohydroxy acid synthase large subunit from Streptomyces cinnamonensis (see paper)
26% identity, 97% coverage of query (105 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
22% identity, 94% coverage of query (105 bits)
ilvB / AAA93098.1 acetolactate synthase from Streptomyces avermitilis (see paper)
25% identity, 86% coverage of query (105 bits)
P42463 acetolactate synthase (EC 2.2.1.6) from Corynebacterium glutamicum (see paper)
23% identity, 95% coverage of query (103 bits)
Q8RL88 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvB / AAL99356.1 acetohydroxy acid synthase large subunit from Geobacillus stearothermophilus (see paper)
25% identity, 92% coverage of query (103 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
23% identity, 84% coverage of query (92.8 bits)
1powA The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from lactobacillus plantarum
22% identity, 93% coverage of query (87.0 bits)
4feeA High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal b (see paper)
22% identity, 93% coverage of query (86.7 bits)
2ezuA Pyruvate oxidase variant f479w in complex with reaction intermediate 2-acetyl-thiamin diphosphate
22% identity, 93% coverage of query (86.7 bits)
2ez9A Pyruvate oxidase variant f479w in complex with reaction intermediate analogue 2-phosphonolactyl-thiamin diphosphate
22% identity, 93% coverage of query (86.7 bits)
2ez8A Pyruvate oxidase variant f479w in complex with reaction intermediate 2-lactyl-thiamin diphosphate
22% identity, 93% coverage of query (86.7 bits)
2ez4B Pyruvate oxidase variant f479w
22% identity, 93% coverage of query (86.7 bits)
1y9dD / P37063 Pyruvate oxidase variant v265a from lactobacillus plantarum (see paper)
22% identity, 93% coverage of query (82.0 bits)
P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
22% identity, 95% coverage of query (80.9 bits)
P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
22% identity, 95% coverage of query (78.2 bits)
3ea4A Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron-ester
23% identity, 95% coverage of query (77.4 bits)
3e9yA Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron
23% identity, 95% coverage of query (77.4 bits)
7tzzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase p197t mutant in complex with bispyribac-sodium
22% identity, 95% coverage of query (76.6 bits)
5k3sA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, bispyribac-sodium
22% identity, 95% coverage of query (76.3 bits)
ILVB_ARATH / P17597 Acetolactate synthase, chloroplastic; AtALS; Acetohydroxy-acid synthase; Protein CHLORSULFURON RESISTANT 1; EC 2.2.1.6 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
P17597 acetolactate synthase (EC 2.2.1.6) from Arabidopsis thaliana (see 8 papers)
22% identity, 95% coverage of query (76.3 bits)
8et4A Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
22% identity, 95% coverage of query (76.3 bits)
5wj1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam
22% identity, 95% coverage of query (76.3 bits)
5k6tA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, propoxycarbazone-sodium
22% identity, 95% coverage of query (76.3 bits)
5k6rA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl
22% identity, 95% coverage of query (76.3 bits)
1z8nA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with an imidazolinone herbicide, imazaquin
22% identity, 95% coverage of query (76.3 bits)
1yi1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
22% identity, 95% coverage of query (76.3 bits)
1yi0A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
22% identity, 95% coverage of query (76.3 bits)
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Lawrence Berkeley National Laboratory