Searching for up to 100 curated homologs for 8499800 FitnessBrowser__Miya:8499800 (521 a.a.)
Found high-coverage hits (≥70%) to 42 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q0PC50 aspartate ammonia-lyase (EC 4.3.1.1) from Campylobacter jejuni (see paper)
56% identity, 89% coverage of query (542 bits)
Q9HTD7 aspartate ammonia-lyase (EC 4.3.1.1) from Pseudomonas aeruginosa (see paper)
58% identity, 90% coverage of query (521 bits)
6wngA / A0A077EBQ3 Crystal structure of an aspartate ammonia-lyase from elizabethkingia anophelis nuhp1
56% identity, 89% coverage of query (509 bits)
3oceA / Q2YLW1 Crystal structure of fumarate lyase:delta crystallin from brucella melitensis bound to cobalt
57% identity, 88% coverage of query (499 bits)
3r6qA A triclinic-lattice structure of aspartase from bacillus sp. Ym55-1
53% identity, 88% coverage of query (497 bits)
3r6vG / Q9LCC6 Crystal structure of aspartase from bacillus sp. Ym55-1 with bound l- aspartate (see paper)
53% identity, 88% coverage of query (496 bits)
Q9LCC6 aspartate ammonia-lyase (EC 4.3.1.1) from Bacillus sp. (in: Bacteria) (see 4 papers)
53% identity, 88% coverage of query (495 bits)
AspA / b4139 aspartate ammonia-lyase (EC 4.3.1.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
aspA / P0AC38 aspartate ammonia-lyase (EC 4.3.1.1) from Escherichia coli (strain K12) (see paper)
ASPA_ECOLI / P0AC38 Aspartate ammonia-lyase; Aspartase; EC 4.3.1.1 from Escherichia coli (strain K12) (see paper)
P0AC38 aspartate ammonia-lyase (EC 4.3.1.1) from Escherichia coli (see 2 papers)
aspA / RF|NP_418562 aspartate ammonia-lyase from Escherichia coli K12 (see 3 papers)
53% identity, 88% coverage of query (469 bits)
A5Y6J1 fumarate hydratase (EC 4.2.1.2) from Streptomyces thermovulgaris (see paper)
51% identity, 89% coverage of query (386 bits)
FUMH_YEAST / P08417 Fumarate hydratase, mitochondrial; Fumarase; EC 4.2.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 7 papers)
P08417 fumarate hydratase (EC 4.2.1.2) from Saccharomyces cerevisiae (see 2 papers)
45% identity, 88% coverage of query (385 bits)
A0A251UZF1 fumarate hydratase (EC 4.2.1.2) from Helianthus annuus (see paper)
44% identity, 89% coverage of query (379 bits)
FUM2 / Q9FI53 fumarase (EC 4.2.1.2) from Arabidopsis thaliana (see paper)
FUM2_ARATH / Q9FI53 Fumarate hydratase 2; AtFUM2; Fumarase 2; EC 4.2.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9FI53 fumarate hydratase (EC 4.2.1.2) from Arabidopsis thaliana (see 4 papers)
45% identity, 89% coverage of query (377 bits)
FUMH_RAT / P14408 Fumarate hydratase, mitochondrial; Fumarase; EC 4.2.1.2 from Rattus norvegicus (Rat) (see paper)
P14408 fumarate hydratase (EC 4.2.1.2) from Rattus norvegicus (see paper)
44% identity, 90% coverage of query (373 bits)
FUMC_RHIME / Q92PB6 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
45% identity, 89% coverage of query (372 bits)
FUMH_MOUSE / P97807 Fumarate hydratase, mitochondrial; Fumarase; EF-3; EC 4.2.1.2 from Mus musculus (Mouse) (see 3 papers)
45% identity, 90% coverage of query (372 bits)
FH / P07954 fumarate hydratase monomer (EC 4.2.1.2) from Homo sapiens (see 7 papers)
FUMH_HUMAN / P07954 Fumarate hydratase, mitochondrial; Fumarase; HsFH; EC 4.2.1.2 from Homo sapiens (Human) (see 10 papers)
P07954 fumarate hydratase (EC 4.2.1.2) from Homo sapiens (see 3 papers)
44% identity, 90% coverage of query (370 bits)
FUMH_PIG / P10173 Fumarate hydratase, mitochondrial; Fumarase; EC 4.2.1.2 from Sus scrofa (Pig) (see paper)
45% identity, 90% coverage of query (370 bits)
A0A251UH44 fumarate hydratase (EC 4.2.1.2) from Helianthus annuus (see paper)
43% identity, 89% coverage of query (370 bits)
P55250 fumarate hydratase (EC 4.2.1.2) from Rhizopus arrhizus (see 2 papers)
44% identity, 89% coverage of query (369 bits)
7lubB / P07954 Crystal structure of recombinant human fumarase in complex with d-2- amino-3-phosphono-propionic acid (see paper)
44% identity, 88% coverage of query (369 bits)
FUM1_ARATH / P93033 Fumarate hydratase 1, mitochondrial; AtFUM1; Fumarase 1; EC 4.2.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
P93033 fumarate hydratase (EC 4.2.1.2) from Arabidopsis thaliana (see 4 papers)
44% identity, 89% coverage of query (364 bits)
Q13VI0 fumarate hydratase (EC 4.2.1.2) from Paraburkholderia xenovorans (see paper)
43% identity, 88% coverage of query (362 bits)
fumC / O25883 fumarase (EC 4.2.1.2) from Helicobacter pylori (strain ATCC 700392 / 26695) (see paper)
40% identity, 89% coverage of query (359 bits)
7c18B / Q65UJ3 Crystal structure of fumarasec from mannheimia succiniciproducens in complex with fumarate
43% identity, 88% coverage of query (357 bits)
Q5SKT5 fumarate hydratase (EC 4.2.1.2) from Thermus thermophilus (see paper)
42% identity, 89% coverage of query (354 bits)
FumC / b1611 fumarase C (EC 4.2.1.2) from Escherichia coli K-12 substr. MG1655 (see 28 papers)
fumC / P05042 fumarase C (EC 4.2.1.2) from Escherichia coli (strain K12) (see 26 papers)
FUMC_ECOLI / P05042 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Escherichia coli (strain K12) (see 8 papers)
43% identity, 88% coverage of query (349 bits)
1fuoA / P05042 FumarasE C with bound citrate (see paper)
43% identity, 88% coverage of query (347 bits)
1fuqA Fumarase with bound 3-trimethylsilylsuccinic acid
43% identity, 88% coverage of query (347 bits)
1fupA Fumarase with bound pyromellitic acid
43% identity, 88% coverage of query (347 bits)
Q8NRN8 fumarate hydratase (EC 4.2.1.2) from Corynebacterium glutamicum (see 2 papers)
43% identity, 87% coverage of query (343 bits)
FUMC_RICPR / Q9ZCQ4 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Rickettsia prowazekii (strain Madrid E) (see paper)
Q9ZCQ4 fumarate hydratase (EC 4.2.1.2) from Rickettsia prowazekii (see paper)
40% identity, 89% coverage of query (334 bits)
FUMC_MYCTU / P9WN93 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
P9WN93 fumarate hydratase (EC 4.2.1.2) from Mycobacterium tuberculosis (see paper)
44% identity, 88% coverage of query (328 bits)
4adlA Crystal structures of rv1098c in complex with malate
44% identity, 88% coverage of query (328 bits)
4apbD / P9WN93 Crystal structure of mycobacterium tuberculosis fumarase (rv1098c) s318c in complex with fumarate (see paper)
44% identity, 88% coverage of query (325 bits)
6s88A Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(2-methoxy-5-((1,2,4,5-tetrahydro- 3h-benzo[d]azepin-3-yl)sulfonyl)phenyl)-2-(4-oxo-3,4- dihydrophthalazin-1-yl)acetamide
42% identity, 88% coverage of query (303 bits)
6s7wA Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(5-(azepan-1-ylsulfonyl)-2- methoxyphenyl)-2-(quinolin-4-yl)acetamide
42% identity, 88% coverage of query (303 bits)
6s7sA Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(2-methoxy-5-(n-phenylsulfamoyl) phenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide
42% identity, 88% coverage of query (303 bits)
6s7uA Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(5-(azepan-1-ylsulfonyl)-2- methoxyphenyl)-2-(1h-indol-3-yl)acetamide
42% identity, 88% coverage of query (303 bits)
6s7kA Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(2-methoxy-5-(n-methylsulfamoyl) phenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide
42% identity, 88% coverage of query (303 bits)
6s43A Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(5-(azocan-1-ylsulfonyl)-2- methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide
42% identity, 88% coverage of query (303 bits)
6s7zA Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(5-((3,4-dihydroisoquinolin-2(1h)- yl)sulfonyl)-2-methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl) acetamide
42% identity, 88% coverage of query (300 bits)
5f91A Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator (n-(5-(azepan-1-ylsulfonyl)-2- methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide)
42% identity, 88% coverage of query (291 bits)
Build an alignment for 8499800 and 42 homologs with ≥ 30% identity
Or download the sequences
Or start over
Lawrence Berkeley National Laboratory